Clinical manifestations of reproductive health and life quality in fertile age women with subclinical hypothyroidism in conditions of comorbidity

2017 ◽  
pp. 54-56
Author(s):  
L.M. Varchenko ◽  

The objective: to evaluate the clinical manifestations of reproductive health and quality of life (QOL) disorders in women of reproductive age with high comorbidity against subclinical hypothyroidism (SHT) and manifest hypothyroidism (MHT). Materials and methods. 113 cases of SHT (1st group) and 65 cases of MHT (2 nd group) in women of reproductive age were analyzed. The diagnosis of hypothyroidism is established on the basis of data of anamnesis, physical examination, ultrasound of the thyroid gland and determination of thyroid-stimulating hormone levels and free thyroxine in the blood by electroluminescence. Results. Assessment of QoL using the MOS SF-36 questionnaire was performed in women of reproductive age with SHT, with a high (61.9%) level of menstrual irregularities, gynecological (74.3%) and extragenital (82.3%) diseases, which indicates High comorbidity. It was revealed mainly the average values of QoL on almost all scales, except for emotional functioning. In women with MHT, with extremely high comorbidity (in 100% of cases), the QL values were reduced and only on the scale of "pain" - within the average. The conclusion. The data obtained make it possible to recommend the definition of quality of life indicators in women of reproductive age with subclinical hypothyroidism in the practice of a gynecologist as an integral characteristic of health. Key words: subclinical hypothyroidism, menstrual irregularities, comorbid conditions, quality of life, MOS SF-36 questionnaire, integral health indicators.

2019 ◽  
Vol 35 (2) ◽  
Author(s):  
Semra Kocaoz ◽  
Rabiye Cirpan ◽  
Arife Zuhal Degirmencioglu

Objectives: To investigate the prevalence and impacts of heavy menstrual bleeding (HMB) on anemia, fatigue, and the quality of life (QoL) in women of reproductive age. Methods: This study was conducted among 306 women of reproductive age who presented at the internal medicine outpatient departments of the training and research hospital of a university. The data of the study were collected by the “Data collection form”, “SF-36 Quality of Life Scale (SF-36 QoLS)” and “Brief Fatigue Inventory (BFI)”. Results: The prevalence of HMB in women of reproductive age was 37.9%. The ferritin level and physical functions were found to decrease significantly as the duration of menstruation increased (p<0.05). Besides, a positive but very weak relationship was found between the menstruation duration and the subdimensions of the global BFI and the general health perception subscale of the SF-36 QoLS (p<0.05). Conclusion: It was determined that HMB is common and has negative effects on anemia, fatigue and some subdimensions of the QoL. Regular screening for HMB that may not be expressed by many women may therefore be useful in preventing and resolving the health problems that it will cause. How to cite this:Kocaoz S, Cirpan R, Degirmencioglu AZ. The prevalence and impacts heavy menstrual bleeding on anemia, fatigue and quality of life in women of reproductive age. Pak J Med Sci. 2019;35(2):---------. doi: https://doi.org/10.12669/pjms.35.2.644 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Author(s):  
Kaminskiy Viacheslav Volodymyrovych ◽  
Suslikova Lidiya Viktorivna ◽  
Serbeniuk Anastasia Valeriivna ◽  
Dercach Andriy Dmytrovych

The article presents data on the prevalence of thyroid hormonal disorders and the establishment of their relationship between the state of mental health and the functional state of body systems in women who participated in hostilities who suffered contusions. We aimed to assessing the prevalence and effectiveness of the diagnosis of thyroid dysfunction in women of childbearing age with impaired reproductive health who participated in hostilities and suffered contusions, to improve treatment and rehabilitation measures and quality of life of these women.


2020 ◽  
pp. 59-63
Author(s):  
I. Ventskivska ◽  
◽  
О. Proshchenko ◽  
Ya. Vitovsky ◽  
S. Markitanyuk ◽  
...  

Hysterectomy, performed in reproductive age, undoubtedly causes a decrease in all parameters of quality of life and contributes to the development of imbalance of hormonal homeostasis, psycho-emotional, vegetative-neurotic symptoms, increasing sexual and urogenital dysfunction, impeding psycho-social adaptation in the family,the professional and intellectual spheres of a woman’s life. This aspect is often overlooked by surgeons when evaluating the effectiveness of treatment, although it has a significant impact on recovery from surgery. The article presents data on experimental psychological research, evaluation of the severity of urogenital dysfunction using a standardized POP-Q system, characteristics of quality of life parameters both at the stage of preoperative observation and within 1, 3 and 5 years after surgery in 80 women of reproductive age with uterine fibroids who have undergone vaginal hysterectomy. The comparison group included 60 patients with hysterectomy performed by abdominal access. According to the results of this study, in women of reproductive age after radical surgery for fibroids, it was determined that the leading violations of quality of life after hysterectomy are general somatic symptoms, psycho-emotional disorders, genitourinary and sexual disorders. Radical operations for uterine fibroids cause an increase in the proportion of urogenital disorders, among which the most important are urinary incontinence and prolapse, the clinical manifestations of which have a negative impact on, including the psychosocial sphere, while reducing quality of life. Today there is no consensus on the degree of impact of radical surgery for uterine fibroids on the versatility of metabolic and hormonal homeostasis, the formation of psychovegetative symptom complex, and as a consequence, the impact on quality of life, which necessitates a validated method of quality of life optimization of the rehabilitation program with personalized consideration of the leading factors of status comorbidity when planning surgical treatment. Keywords: uterine fibroids, hysterectomy, quality of life parameters.


2020 ◽  
Vol 18 (6) ◽  
pp. 43-48
Author(s):  
R. I. GABIDULLINA ◽  
◽  
E. I. GALIMYANOVA ◽  
V. I. EREMKINA ◽  
A. M. SHARAPOVA ◽  
...  

The purpose — to evaluate the effect of combined oral contraceptive containing 17β-estradiol on sexuality, severity of depression and quality of life in women of reproductive age. Material and methods. The study involved 53 women in need of contraception aged 18 to 50 years. For the contraceptive purpose women used COC containing 1,5 mg of 17 β -estradiol (E2) and 2,5 mg of nomegestrol acetate (NOMAC) (E2/NOMAC). The questionnaires used in the study are: Female Sexuality Function Index (FSFI-6), Beck Depression Inventory, SF-36 — for evaluating Health-Related Quality of Life. The survey was conducted before and after six months of E2/NOMAC intake; the correlations between the studied parameters and the level of sex hormones in patient’s blood sample were determined. Results. The intake of E2/NOMAC for 6 months did not have negative effect on Female Sexuality Function Index. At the same time, a statistically significant improvement up to 5 points was revealed in such parameters as sexual satisfaction (p = 0,03) and lubrication (p < 0,001). There was a significant decrease in the frequency and severity of depression measured by the Beck Depression Inventory. The Short Form-36 Health Survey revealed a tendency to improve the physical and mental health components of the quality of life (p> 0,05). The change in total testosterone level had a moderate negative relationship with the change in Female Sexuality Function Index (r = — 0,32; p = 0,02). Conclusion. The intake of combined oral contraceptive containing 17β-estradiol for 6 months was associated with no adverse impact on female sexuality and quality of life in women of reproductive age, and reduced the levels of frequency and severity of depression.


2020 ◽  
Author(s):  
Kizito Omona

Fibroid, also called leiomyomas, is common tumor of the uterus. Usually, women of reproductive age are at risk of getting it. However, majority of these women develop fibroid (s) by the age of 50 years. This condition usually causes painful and unpleasant symptoms such as; heavy bleeding, prolonged periods, inter-menstrual bleeding, abdominal pain and cramps, anemia, pelvic pain and pain during sexual intercourse, among others. Abnormal bleeding, such as bleeding that occurs with fibroids and heavy periods, often lasts more than 10 days per month. This fibroid symptom involves persistent bleeding between cycles, which can severely impact one’s quality of life. Abnormal bleeding, especially in fibroids, can be taken as missing three or more periods in a woman who had been having regular monthly period, or periods that last less than 21 days or more than 35 days apart from each other. Another indication of an abnormal period is bleeding through multiple pads and tampons in a short amount of time.


Author(s):  
O.E. Fedorenko ◽  
K.V. Koladenko ◽  
L.V. Sologub

The COVID-19 pandemic, political and economic factors, the latest technological advances, environmental changes in the world — all this significantly influenced the awareness of the quality of life by most of the population. For us, as clinicians and lecturers of the Department of Dermatology and Venereology with a course of cosmetology at Bogomolets National Medical University, this became obvious after the forced abandonment of the usual «live» teaching and the transition to distance learning at Zoom in March 2020, and at the same time the re-profiling of the clinical base of the department for inpatient treatment of only COVID-19 patients with the simultaneous discharge of specialized dermatological patients.During the pandemic, we were in fact deprived of the possibility of further professional contact with specialized patients with dermatological diseases. We only had the technical ability to contact the 4th year students of NMU online. It was decided to take advantage of this opportunity not only for their distance teaching of the basics of dermatovenerology, but also for determining (clarifying) their psychostatus with the help of appropriate tests. Objective — to conduct a remote monitoring study of the quality of life (QOL) indicators in young medical workers (students) against the background of the negative informative influence of the media due to the forced long-term stay in a stressful situation of lockdown and strict multi-week quarantine caused by the COVID19 pandemic. Materials and methods. QOL was assessed using the Health Status Survey (SF36) which is one of general (non-specialized) questionnaires. Results and discussion. During the period from March to June, there were noticeable changes in the self-esteem of somatically quite healthy fourth-year medical students of their own QOL, both on several SF-36 scales and in general. This was despite the fact that none of them and their family members were infected with COVID-19 or had any clinical manifestations of this disease for all 3 months. In general, during this time, the existing changes were negative, albeit to varying degrees, according to individual scales. In conditions of remote contact, it became technically possible and scientifically justified to use questionnaires to determine QOL in statistically significant samples of voluntary respondents. Conclusions. We find it hypothetically possible to consider changes in QOL self-esteem in general and according to individual SF-36 scales as a kind of unconventional but quite objective and visual diagnostic test for preclinical (early) determination of the threat of formation and development of psychosomatic disorders in any adult patient who saw a family doctor.


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