scholarly journals Comparative efficacy of kneading massage and pulsed mode ultrasound in the management of chronic knee osteoarthritis

2021 ◽  
Vol 18 (4) ◽  
pp. 275-280
Author(s):  
Adesola O. Ojoawo ◽  
◽  
Wasiu Abiodun Fatai ◽  
Keyword(s):  
Knee Osteoarthritis ◽  
Joint Stiffness ◽  
The Elderly ◽  
Treatment Session ◽  
Osteoarthritis Of The Knee ◽  
Pulsed Ultrasound ◽  
Pulsed Mode ◽  
Significant Difference ◽  
Massage Group ◽  
Ultrasound Group

Introduction. Osteoarthritis of the knee is the most common presentation of osteoarthritis with prevalence between 12% and 35% of general population and is considered the leading cause of musculoskeletal disability in the elderly population worldwide. Aim. The study compared efficacy of kneading massage and pulsed ultrasound on pain, joint stiffness and difficulty in knee osteoarthritis (KOA). Material and methods. Fifty subjects with radiological evidence of KOA participated in the study. They were randomly allocated into kneading massage group (KMG) (25) and Ultrasound group (USG) (25). KMG received kneading massage for 7 minutes while USG received pulsed mode ultrasound for 15 minutes. Treatment was twice in a week for six weeks. Pain intensity (PI), joint stiffness and difficulty were assessed pre, 3rd and 6th weeks of treatment session with semantic differential scale and WOMAC. The data were analyzed using descriptive and inferential statistics, alpha level was set at 0.05 Results. There was a significant difference in present PI (F=11.45,P=0.001) and stiffness (F= 11.32, P=0.003) in USG. There was a significant reduction in PI (F=7.95, P=0.001) and joint stiffness (F=8.86, P=0.003) in KMG. At the 6th week, there was a significant differences in PI (t=12.23,P=0.000) and stiffness (t=8.08, P=0.000) when USG (3.00+0.4, vs 7.14+ 1.49) was compared with KMG (3.16+0.5 vs 7.50+1.5). Conclusion. Ultrasound (US) and kneading massage (KM) reduced PI and joint stiffness of KOA effectively; however US reduced PI than KM while KM reduces joint stiffness than US.

scholarly journals Evaluating Meridian-Sinew Release Therapy for the Treatment of Knee Osteoarthritis

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Song Wei ◽  
Zhi-Huang Chen ◽  
Wei-Feng Sun ◽  
Geng-Peng Zhang ◽  
Xiao-Hao Li ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Symptom Score ◽  
Joint Stiffness ◽  
The Elderly ◽  
Outcome Evaluation ◽  
Total Symptom Score ◽  
Control Group ◽  
Osteoarthritis Of The Knee ◽  
Functional Movement ◽  
The Impact

Objective. In recent years, public health experts have concluded that the impact of osteoarthritis is equal in magnitude to that of cardiovascular disease. Osteoarthritis of the knee is prevalent in the elderly population; however, there are currently no effective treatments for this condition. In this study, we investigated the efficacy of “meridian-sinew release,” a newly developed technique which entails using a meridian-sinew scope and a meridian-sinew knife to treat osteoarthritis of the knee.Methods. Patients (N=90) with knee osteoarthritis were prospectively randomized to meridian-sinew release therapy, acupuncture therapy, or drug therapy groups, respectively. Outcome evaluation included pain, stiffness, physiological function, total symptom score, and overall changes in the condition.Results. After 12 weeks, patients' general assessment (GA) and doctors' general assessment (GA) of the condition were not significantly different among the three groups. However, significant differences in primary endpoint pain, joint stiffness, and total symptom score were found between the meridian-sinew group and the acupuncture group and between the meridian-sinew group and the control group (P<0.05). No adverse events occurred during the trial.Conclusion. Our study suggests that meridian-sinew release therapy can improve knee osteoarthritis, alleviate joint pain, and improve functional movement disorder. It is a safe and effective treatment for knee osteoarthritis.

scholarly journals Comparative Observational Study on the Effects of Intra-articular Hominis Placenta Pharmacopuncture and Acupoint Hominis Placenta Pharmacopuncture for Knee Osteoarthritis Patients

2021 ◽  
Vol 38 (1) ◽  
pp. 60-65
Author(s):  
Yeo-bin Park ◽  
Chang Beohm Ahn ◽  
Yun-Leong Park ◽  
Ji-Won Baek ◽  
Won-Ho Kong ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Medical Records ◽  
Joint Space ◽  
Osteoarthritis Of The Knee ◽  
Analog Scale ◽  
Degenerative Osteoarthritis ◽  
Significant Difference ◽  
Group A ◽  
Vas Scores ◽  
Group B

The aim of this case report was to observe the effects of intra-articular hominis placenta pharmacopuncture (HPP). Based on the medical records patients who received intra-articular treatment or received acupoint pharmacopuncture treatment, a comparison was made. There were 35 patients who were hospitalized for degenerative osteoarthritis of the knee joint from the 1<sup>st</sup> October 2019 to 26<sup>th</sup> September 2020. There were 14 patients who were treated with HPP in the intra-articular joint space (Group A), and 14 patients who were treated with HPP at specific acupoints (Group B). The outcome effects were measured using the Korean Western Ontario and Mc (KWOMAC) the visual analog scale (VAS) before the first treatment, and after the fifth treatment. The KWOMAC (<i>p</i> < 0.001) and the VAS scores (<i>p</i> < 0.001) in Groups A and B significantly improved after treatment compared with before treatment. When comparing Group A improvement with Group B improvement using the KWOMAC there was no statistically significant difference however, when using the VAS scores, Group A treatment was statistically more effective compared with Group B (<i>p</i> = 0.002). This study indicated that HPP may be an effective treatment for knee osteoarthritis. Moreover, intra-articular HPP may be more effective than acupoint HPP for knee osteoarthritis.

scholarly journals Functional and Radiological Comparison of Umbilical Cord Mesenchymal Stem Cells, Somatotropin, and Hyaluronic Acid Injection for Cartilage Repair in Early Osteoarthritis of the Knee: A Randomized Controlled Trial

2020 ◽  
Vol 8 (5_suppl5) ◽  
pp. 2325967120S0004
Author(s):  
J Fiolin ◽  
IH Dilogo ◽  
AMT Lubis ◽  
JA Pawitan ◽  
IK Liem ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Hyaluronic Acid ◽  
Knee Osteoarthritis ◽  
Umbilical Cord ◽  
Controlled Trial ◽  
Osteoarthritis Of The Knee ◽  
Significant Difference ◽  
Group A ◽  
Ikdc Score

The umbilical cord-mesenchymal stem cells (UC-MSC) has been shown to improve the viability of degenerated chondrocytes in knee osteoarthritis (KOA) in cellular level. Additional somatotropin injection also shown clinical improvement in patients. The present trial is conducted to assess the efficacy of umbilical cord mesenchymal stem cells (UC-MSC) in comparison to somatotropin and hyaluronic acid (HA) injection to treat and slow the progression of knee osteoarthritis. Methods: This study was conducted from January 2016 to April 2018 in Cipto Mangunkusumo General Hospital. A total of 28 knees from 15 patients with early KOA Kellgren Lawrence I-II were randomized into three groups. Group A was treated with 1x106 units of intra-articular UC-MSCs + 2 ml HA followed with 2 consecutive weeks of HA injection; group B was treated with the same dose of HA with additional 8 IU of Somatotropin; group C was treated as control. The International Knee Documentation Committee (IKDC) score, The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), visual analogue score (VAS), were assessed on the 1st and 3rd month, then every 3rd month until 12 months. Cartilage evaluation using MRI cartigram were performed at pre-implantation, and after the 6th and 12th month after implantation Results: General improvement were observed in all groups after 6 and 12 months. The IKDC score improved significantly among groups after 12 months (69.43 [48.3-89.66], 79.31 [51.72-90.08], and 75.9 [67.82-97.7] in group A, B, and C, respectively, p =0.005). We did not find a significant difference between groups in VAS and WOMAC results. However, we observed a medial T2 improvement in group A (39.55 [32.65-67.85] initially and 45.64 [38.12-70.65] 12 months after implantation). Conclusion: Injection of UC-MSC could improve knee function and cartilage profile in early KOA. However, further multicenter studies with larger samples are required to investigate the efficacy of such treatment for treating knee osteoarthritis.

scholarly journals Effectiveness of Combination Myofascial Release and Kinesio Taping Intervention on Range of Motion Improvement in Elderly with Knee Osteoarthritis

2020 ◽  
Vol 1 (1) ◽  
pp. 13-16
Author(s):  
Afif Zainuri Wafiq ◽  
Atika Yulianti
Keyword(s):  
Knee Osteoarthritis ◽  
Range Of Motion ◽  
Cartilage Damage ◽  
The Elderly ◽  
Rank Test ◽  
Control Group ◽  
Case Group ◽  
Myofascial Release ◽  
Kinesio Taping ◽  
Significant Difference

Introduction: Knee Osteoarthritis is a condition that frequently occurs in elderly which has a major impact on the elderly’s disability. As a degenerative disease, knee osteoarthritis occurs due to cartilage damage which is then accompanied by inflammation, pain, stiff joints and muscles thereby limiting the range of motion. This research aims to compare the effect of Kinesio taping and a combination of myofascial release and Kinesio taping intervention on ROM improvement in elderly with knee osteoarthritis.Methods: This study applies a quasi-experimental design with a non-equivalent group approach. Goniometer is applied as a measurement instrument. 25 people participated in this study who were recruited through purposive sampling. The sample was then divided into 2 groups which were given treatment 3 times a week in one month. The control group with Kinesio Taping treatment consisted of 14 samples and the case group with a combination treatment of myofacial release and Kinesio taping consisted of 11 samples. Furthermore, data analysis was performed with the Shapiro Wilk test, Wilcoxon rank test, and the Mann-Whitney test using SPSS version 25.Results: The comparison test results show that the significance value of p yields 0.6> 0.05, therefore H1 is rejected, and H0 is accepted. The interpretation of these results is that there is no significant difference between the effects of Kinesio taping and the combination of myofacial release and Kinesio taping on increasing ROM in the elderly with the risk of knee osteoarthritis.Conclusion: This study shows that there is no significant difference in the effect of the treatment of Kinesio taping and the combination of myofacial release and Kinesio taping in increasing ROM in the elderly with osteoarthritis.

scholarly journals Influence of the physical activity in the elderly people diagnosed with knee osteoarthritis during the pandemic period caused by COVID-19

2021 ◽  
Vol 12 (Vol.12, no.1) ◽  
pp. 87-93
Author(s):  
Sînziana Călina SILIŞTEANU ◽  
Andrei Emanuel SILIŞTEANU ◽  
Juliánna SZAKÁCS
Keyword(s):  
Physical Activity ◽  
Knee Osteoarthritis ◽  
Elderly People ◽  
Functional Capacity ◽  
Joint Stiffness ◽  
The Elderly ◽  
Movement Behavior ◽  
Study Group ◽  
Outpatient Basis ◽  
Joint Stability

Introduction. Knee osteoarthritis is considered to be a chronic disease that affects the joints by causing pain, joint stiffness and decreased functional capacity. Regular physical activity can keep and increase functional capacity, it can reduce pain by improving movement behavior. The disruption of the sedentary behavior of the elderly patients with knee osteoarthritis can lead to improved physical function and general health. The purpose of this paper is to point out the role of physical activity in the elderly people diagnosed with knee osteoarthritis during the COVID-19 pandemic. Material and method. A total of 155 patients diagnosed (clinical and imaging) with knee ostoarthritis, who were treated on an outpatient basis, from May to September 2020, were studied. The parameters assessed in the study were pain, joint stiffness, the ability to carry out daily activities, anxiety and quality of life. Results and discussion.The studied group of patients was homogeneous in terms of the weight by age group and gender. Higher values were recorded in the study group in the evaluation of patients based on scales, the results being statistically significant, with value for p<0.05, which means that the hypothesis was validated. Conclusions. Patients of the study group recorded improvementin of functional capacity, joint stability and static and dynamic balance, which allowed a faster reintegration into the family and society. Keywords: physical activity, pain, elderly people, knee osteoarthritis,

Efficacy of tele-rehabilitation compared with office-based physical therapy in patients with knee osteoarthritis: A randomized clinical trial

2017 ◽  
Vol 24 (8) ◽  
pp. 560-565 ◽  
Author(s):  
Kamran Azma ◽  
Zahra RezaSoltani ◽  
Farid Rezaeimoghaddam ◽  
Afsaneh Dadarkhah ◽  
Sarasadat Mohsenolhosseini
Keyword(s):  
Clinical Trial ◽  
Physical Therapy ◽  
Knee Osteoarthritis ◽  
Randomized Clinical Trial ◽  
Age Groups ◽  
Repeated Measure ◽  
Osteoarthritis Of The Knee ◽  
Post Intervention ◽  
Significant Difference ◽  
The Mean

Introduction Knee osteoarthritis is a major cause of disability among the middle to senior age groups. Despite being effective, office-based physical therapy (OBPT) needs professional human resources and is both costly and time-consuming. We aimed to compare the efficacy of tele-rehabilitation (tele-rehab) compared with OBPT in patients with knee osteoarthritis. Methods In this randomized clinical trial, patients with symptomatic osteoarthritis of the knee were assigned to participate in either a 6-week home-based tele-rehab or an OBPT program between 2015 and 2016. Our primary outcome was the mean change from the baseline until 1 and 6 month's post-intervention in scores of the Knee injury and Osteoarthritis Outcome Score (KOOS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). We used analysis of variance for the repeated measure statistical test. Results A total of 54 patients entered the final analysis, with 27 in each group. The mean age of the patients was 58.2 ± 7.41 years and 60.2% were female. In the tele-rehab and OBPT group, KOOS scores increased from baseline to 6 months post-intervention (50.6 to 83.1 and 49.8 to 81.8) respectively. There was no significant difference between tele-rehab and OBPT groups in any of the studied scales. Discussion The tele-rehab program is as effective as OBPT in improving the function of patients with knee osteoarthritis. Considering the much lower time and cost consumed by tele-rehab, it is the recommended program for the older population living in remote sites.

scholarly journals Efficacy and Safety of Sahastara Remedy Extract Capsule in Primary Knee Osteoarthritis: A Randomized Double-Blinded Active-Controlled Trial

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Narin Kakatum ◽  
Piya Pinsornsak ◽  
Puritat Kanokkangsadal ◽  
Buncha Ooraikul ◽  
Arunporn Itharat
Keyword(s):  
Blood Pressure ◽  
Knee Osteoarthritis ◽  
Controlled Trial ◽  
Essential Medicine ◽  
Ethanolic Extract ◽  
Blood Chemistry ◽  
Osteoarthritis Of The Knee ◽  
Efficacy And Safety ◽  
Double Blind ◽  
Significant Difference

Sahastara (SHT) remedy is a Thai traditional medicine described in the Thai National List of Essential Medicine (NLEM) for the relief of muscle pain. The purpose of this study was to investigate the efficacy and safety of SHT remedy extract capsule for treating primary OA. A phase 2, double-blind, randomized, and controlled trial study was used to determine the clinical efficacy and safety of SHT in comparison with diclofenac for the treatment of knee OA. The outcome of reduce pain was measured from VAS, 100 meter time walk, and the WOMAC score of day 14 and day 28 which should reduce significantly when compared with day 0 and should be equal with or better than diclofenac. Blood pressure and blood chemistry values at day 14 and day 28 did not change when compared with day 0. The results found that SHT remedy ethanolic extract capsule can reduce all OA knee scores at day 14 and day 28 significantly when compared with day 0 and also no significant difference with diclofenac ( P > 0.05 ). The SHT also showed safety values on blood pressure and blood chemistry. The SHT was observed that it had no serious side effect. The results of this study are the first report of using the SHT ethanolic extract capsule in the treatment of primary osteoarthritis of the knee. It can be recommended as an anti-inflammatory herbal drug for reducing pain in knee osteoarthritis patients.

Osteoarthritis of the knee

2018 ◽  
Vol 11 (4) ◽  
pp. 190-197 ◽  
Author(s):  
Raymond Leung
Keyword(s):  
Knee Joint ◽  
Knee Osteoarthritis ◽  
Clinical Assessment ◽  
Elderly Population ◽  
The Elderly ◽  
Osteoarthritis Of The Knee ◽  
Evidence Based ◽  
Management Options ◽  
Common Features ◽  
Athletic Population

Osteoarthritis of the knee is a degenerative condition that is commonly seen in the elderly population and sometimes occurs earlier in the athletic population. Pain and stiffness are common features, which can be debilitating. Clinical assessment of the knee joint requires consideration of its associated muscles, ligaments, tendons, bursae and menisci. The aim of this article is to provide an overview of knee pain assessment, to discuss the diagnosis of knee osteoarthritis, and to review some evidence-based management options.

scholarly journals Efficacy of Piroxicam Mesotherapy in Treatment of Knee Osteoarthritis: A Randomized Clinical Trial

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Hamid Reza Farpour ◽  
Fahime Estakhri ◽  
Mohadese Zakeri ◽  
Reyhaneh Parvin
Keyword(s):  
Knee Osteoarthritis ◽  
The Elderly ◽  
Degenerative Diseases ◽  
Short Term ◽  
Persian Version ◽  
Significant Difference ◽  
Oral Group ◽  
And Function ◽  
Effective Drugs

Introduction. Knee osteoarthritis (KOA) is one of the most common degenerative diseases that lead to pain and disability. Oral NSAIDs are effective drugs used to alleviate symptoms in patients with KOA, but they have several important complications, especially in the elderly. In this study, we evaluated the effectiveness of mesotherapy on pain reduction and improvement of functioning in patients with KOA. Methods. Sixty-two patients with KOA, grade 2-3 of the Kellgren–Lawrence scale, were randomized into two groups: the mesotherapy group, in which two injections were applied with piroxicam at a 10-day interval, and the oral group, in which piroxicam was prescribed for 10 days. The patients were evaluated before the treatment and 2, 4, and 8 weeks after it using the Visual Analogue Scale (VAS), Oxford Knee Scare (OKS), and Western Ontario McMaster University Osteoarthritis Index (WOMAC, Persian version). Results. There was no significant difference in demographic characteristics and baseline pain and function scores between the two groups. After 2, 4, and 8 weeks of follow-up, VAS, WOMAC, and OKS scores significantly improved in both groups (in the mesotherapy group: p value <0.001 in all three scores and in the oral group: p value <0.001 in the VAS scale and p value <0.05 in WOMAC and OKS scores). There was no significant difference between the two groups at any time in the VAS score, but improvement in WOMAC and OKS scales in the mesotherapy group was significantly better (p value <0.05 in both scales [p value <0.03 in OKS and p value <0.02 in WOMAC scales]). Side effects in both groups were not serious: limited heart burn in 32.2% of the total subjects in the oral group and pain at the injection site in 3.2% and bruises in 38.7% of the total subjects in the mesotherapy group. Conclusion. Mesotherapy is an effective and safe treatment modality in patients with mild-to-moderate KOA in the short term. This trial is registered with IRCT2017052434113N1.

scholarly journals Alpha-2-Macroglobulin Not Significantly Better Than Regular PRP For Knee Arthritis Symptoms

2020 ◽  
Vol 8 (7_suppl6) ◽  
pp. 2325967120S0045
Author(s):  
David Klein ◽  
David Bloom ◽  
Kirk Campbell ◽  
Guillem Gonzalez-Lomas ◽  
Michael Alaia ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Platelet Rich Plasma ◽  
Statistical Significance ◽  
The United States ◽  
Joint Disease ◽  
Osteoarthritis Of The Knee ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee ◽  
Significant Difference ◽  
Patient Reported

Objectives: Osteoarthritis, a degenerative and debilitating joint disease, is one of the most prevalent diseases in the United States. Despite the significant burden osteoarthritis can place on an individual and society, nonoperative treatment options are still very limited. Little clinical data exists on the use of injectable macromolecules for the treatment of osteoarthritis of the knee. Alpha-2-macroglobulin (A2M), a naturally occurring macromolecule, inhibits the many endogenous and exogenous proteinases presenting in the pathogenesis of osteoarthritis. To date, no studies exist evaluating the effectiveness of A2M with other intra-articular injectables. The purpose of this study is to compare the clinical effectiveness of intra-articular injection of A2M against both platelet-rich plasma (PRP) and corticosteroids. Methods: This prospective randomized control trial was conducted at a single medical center. Seventy-five patients with symptomatic knee osteoarthritis with Kellgren-Lawrence grade 2 or 3 were randomized into one of three cohorts receiving intra-articular injection. One group was given PRP, one group was given A2M, and one group was given corticosteroids. All groups had blood drawn to simulate A2M preparation. Patient reported outcomes were collected prior to injection, 6 weeks and 12 weeks following injection. Several measures were used for clinical assessment including the visual analog scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Knee Injury and Osteoarthritis Outcome Score (KOOS), Lysholm, and Tegner scores. Results: Seventy-five patients with a mean age of 61.08 (± 8.48) were enrolled between June 2018 and February 2019. At six weeks, the A2M group had the greatest decrease in VAS (-1.60) and WOMAC (-10.9), however, the differences were not statistically significant. Between the injection and the twelve week visit, the A2M group had a statistically significant difference in WOMAC score compared with PRP (-18.43 vs -5.70, p <0.02). Overall, both corticosteroid (-1.57) and A2M (-1.70) had a similar improvement in VAS when compared with PRP (-0.61). These differences were also not statistically significant. Conclusions: Our study demonstrates Alpha 2 Macroglobulin shows similar effectiveness to corticosteroids in the treatment of knee osteoarthritis. Both A2M and corticosteroids appear to show marginally better effectiveness than PRP injection, however the differences are small and did not reach statistical significance in most outcome measures.

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