scholarly journals BIODEGRADABLE GELATIN DECORATED Fe3O4 NANOPARTICLES FOR PACLITAXEL DELIVERY

2018 ◽  
Vol 55 (1B) ◽  
pp. 7 ◽  
Author(s):  
Dai Hai Nguyen
Keyword(s):  
Fe3o4 Nanoparticles ◽  
Drug Loading ◽  
Spherical Shape ◽  
Average Diameter ◽  
Precipitation Method ◽  
Loop Analysis ◽  
Transmission Electron ◽  
Potential Applications ◽  
Size And Morphology ◽  
Co Precipitation

The objective of this study is to prepare biodegradable iron oxide nanoparticles with gelatin (GEL) for paclitaxel (PTX) delivery. In detail, Fe3O4 nanoparticles were prepared and then coated them with GEL (Fe3O4@GEL) conjugate by co–precipitation method. Furthermore, the formation of Fe3O4@GEL was demonstrated by Fourier transform infrared (FT–IR) and powder X–ray diffraction (XRD). The superparamagnetic property of Fe3O4@GEL was also showed by hysteresis loop analysis, the saturation magnetization reached 20.36 emu.g–1. In addition, size and morphology of Fe3O4@GEL nanoparticles were determined by transmission electron microscopy (TEM). The results indicated that Fe3O4@GEL nanoparticles were spherical shape with average diameter of 10 nm. Especially, PTX was effectively loaded into the coated magnetic nanoparticles, 86.7 ± 3.2 % for drug loading efficiency and slowly released up to 5 days. These results suggest that the potential applications of Fe3O4@GEL nanoparticles in the development of stable drug delivery systems for cancer therapy.

SYNTHESIS OF MO-CO ALLOY NANOPOWDER BY CO-PRECIPITATION METHOD FOLLOWED BY H2 REDUCTION

2012 ◽  
Vol 05 ◽  
pp. 142-150
Author(s):  
KAMAL SABERYAN ◽  
SADEGH FIROOZI ◽  
AMIN MORADMAND ◽  
ALI REYHANI
Keyword(s):  
Electron Microscope ◽  
Aqueous Media ◽  
Spherical Shape ◽  
Xrd Analysis ◽  
Hydrogen Gas ◽  
Precipitation Method ◽  
Transmission Electron ◽  
Bed Materials ◽  
Size And Morphology ◽  
Co Precipitation

Cobalt-Molybdenum alloy nanopowder has magnetic properties and is used as catalyst for production of carbon nanotubes. Properties of this nanopowder depend on, for example, its size, morphology and internal residual stress. Synthesis of nanopowder of Molybdenum-Cobalt alloy by co-precipitation in an aqueous media using NH 4 OH as precipitating agent followed by calcination and reduction was investigated. The synthesis was started by dissolving salts of Cobalt and Molybdenum in water. A suspension of alumina or silica powders was used as a bed for precipitation. The effect of bed materials on size and morphology of the precipitate was investigated. The particles observed with scanning electron microscope possess a spherical shape and a needle shape for the samples participated on alumina and silica beds, respectively. XRD analysis of the calcined precipitate showed the formation of mixed oxide of CoMoO 4 as well as single oxides of Co 3 O 4 and MoO 3. Particle size of the precipitate observed with transmission electron microscope was about 100 nm. Finally, the powders were reduced by hydrogen gas in a tubular furnace to prepare metallic nanopowder with composition of Co 3 Mo .

Synthesis of Fe3O4 Nanoparticles Prepared by Various Surfactants and Studying their Characterizations

2008 ◽  
Vol 273-276 ◽  
pp. 22-27 ◽  
Author(s):  
Ali Shokuhfar ◽  
S. Alibeigi ◽  
Mohammad Reza Vaezi ◽  
Sayed Khatiboleslam Sadrnezhaad
Keyword(s):  
Fe3o4 Nanoparticles ◽  
Cetyl Trimethyl Ammonium Bromide ◽  
Precipitation Method ◽  
Ammonium Bromide ◽  
X Ray Diffraction ◽  
Mixed Salt ◽  
Magnetite Fe3o4 ◽  
Cetyl Trimethyl Ammonium ◽  
Size And Morphology ◽  
Co Precipitation

Magnetite (Fe3O4) nanoparticles were prepared simply by the reverse co-precipitation method from the solution of ferrous/ferric mixed salt in the presence of cationic surfactant (cetyl trimethyl ammonium bromide, CTAB) and nonionic surfactant (Polyethylene glycol, PEG) in two concentrations. Meanwhile, Fe3O4 nanoparticles without surfactant are also synthesized under the same condition for comparison. In addition via the reverse co-precipitation method, the pH which is an important factor in synthesis of magnetite was controlled at high values easily. The experimental results reveal that addition of surfactants affected on the size and morphology of the nanoparticles based on the X-ray diffraction (XRD) and scanning electron microscope (SEM) characterizations.

scholarly journals Synthesis, surface modification, and characterization of Fe3O4@SiO2 core@shell nanostructure

2021 ◽  
Vol 10 (1) ◽  
pp. 384-391
Author(s):  
Seham S. Alterary ◽  
Anfal AlKhamees
Keyword(s):  
Particle Size ◽  
Malonic Acid ◽  
Environmental Science ◽  
Focal Point ◽  
Spherical Shape ◽  
Core Shell ◽  
Xrd Diffraction ◽  
Transmission Electron ◽  
Potential Applications ◽  
Co Precipitation

Abstract In recent times, nanoparticles have been the focal point of research in nanoscience due to their wide scope of potential applications in all fields of science. Iron oxide (Fe3O4) nanoparticles (NPs) show incredible magnetic saturation, stability, biocompatibility, and intuitive properties on the surface, which makes them ideal for being utilized in several ways. In the present study, Fe3O4 NPs were synthesized by co-precipitation and further coated with silica (SiO2) to avoid aggregation. Synthesized nanoparticles (Fe3O4@SiO2) were individually functionalized using glycine and malonic acid and characterized by various spectroscopies and microscopies techniques. XRD diffraction analysis showed that the presence of SiO2 did not alter the diffraction pattern peaks, which represented the existence of Fe3O4. The presence of Fe3O4 and SiO2 nanoparticles were further confirmed using EDS. Transmission electron microscope micrographs of the synthesized nanoparticles exhibited spherical shape and confirmed the increase in particle size after coating with SiO2. Also, the analysis of dynamic light scattering showed that the particle size of Fe3O4@SiO2 functionalized with malonic acid (229.433 nm) was greater than those functionalized with glycine (57.2496 nm). However, the surface area was greater in Fe3O4@SiO2-glycine (104.8 m2/g) than Fe3O4@SiO2-malonic acid (26.15 m2/g). The key findings suggest that the synthesized core-shell Fe3O4@SiO2 nanoparticles are a promising candidate for a wide array of applications in the field of medicine and environmental science.

scholarly journals A New Synthesis Route to Prepare Polyaniline (PANI) Nanotubes Containing Magnetic Nanoparticles

2008 ◽  
Vol 54 ◽  
pp. 325-330 ◽  
Author(s):  
Ana Claudia V. De Araújo ◽  
S. Alves ◽  
W.M. Azevedo
Keyword(s):  
Electron Microscopy ◽  
Fe3o4 Nanoparticles ◽  
In Situ Polymerization ◽  
Average Diameter ◽  
Transmission Electron ◽  
New Synthesis ◽  
Co Precipitation ◽  
Tubular Morphology

In this work we report the preparation and characterization of a polyaniline/magnetite (PANI)-Fe3O4 nanocomposite, with average diameter around 50 nm and tubular morphology. The tubular nanocomposite was synthesized by an in situ polymerization of aniline using Fe3O4 nanoparticles as an oxidant agent. The Fe3O4 nanoparticles with narrow size distribution were synthesized by co-precipitation technique and the products were characterized by powder X-ray diffractometry (XRD), Fourier transform infrared (FTIR), scanning electron microscopy (SEM), and transmission electron microscopy (TEM).

Fabrication and Up-Conversion Luminescence of Er3+:Y2O3 Nanoparticles

2008 ◽  
Vol 8 (3) ◽  
pp. 1211-1213 ◽  
Author(s):  
Luo Jun-Ming ◽  
Li Yong-Xiu ◽  
Deng Li-Ping ◽  
Yuan Yong-Rui ◽  
Chen Wei-Fan
Keyword(s):  
Doping Concentration ◽  
Green Emission ◽  
Average Diameter ◽  
Precipitation Method ◽  
Cubic Phase ◽  
X Ray Diffraction ◽  
X Ray ◽  
Radiative Transitions ◽  
Transmission Electron ◽  
Co Precipitation

Y2O3 nanoparticles doped with different concentrations of Er3+ were prepared by the co-precipitation method. X-ray diffraction and transmission electron microscopy results show that Er3+ dissolves completely in the Y2O3 cubic phase. The Er3+:Y2O3 nanoparticles are homogeneous in size and nearly spherical, and the average diameter of the particles after being calcined at 1,000 °C for 2 h is in the range of 40–60 nm. When Er3+:Y2O3 nanoparticles are excited under a 980 nm diode laser, there are two main emission bands: green emission centered at 562 nm corresponding to the 4S3/2/2H11/2 → 4I15/2 radiative transitions and red emission centered at 660 nm corresponding to the 4F9/2 ∼ 4I15/2 radiative transitions. By changing the doping concentration of Er3+ ions, the up-conversion luminescence can be gradually tuned from green to red.

scholarly journals Structural, Optical, Magnetic, Photocatalytic Activity and Related Biological Effects of CoFe2O4 Ferrite Nanoparticles

2021 ◽  
Author(s):  
B. Yalcin ◽  
S. Ozcelik ◽  
K. Icin ◽  
K. Senturk ◽  
B. Ozcelik ◽  
...  
Keyword(s):  
Photocatalytic Activity ◽  
Biological Effects ◽  
Spherical Shape ◽  
Biological Properties ◽  
Heme Iron ◽  
Morphological Properties ◽  
Precipitation Method ◽  
Sem Images ◽  
Potential Applications ◽  
Co Precipitation

Abstract The synthesis of magnetic nano-size spinel ferrites has become an important area of research, due to their several potential applications. In this work, CoFe2O4 nanoparticles were synthesized by the co-precipitation method. Structural, magnetic and photocatalytic properties of cobalt ferrites were analyzed based on their chemical composition considering their biological properties. Structural and morphological properties were investigated by X-ray diffraction analysis (XRD) and SEM respectively. Lattice parameters and cell volumes were calculated from XRD data. SEM images revealed uniform surface morphology and spherical shape of nanoparticles. Magnetization measurements were measured by using Lake Shore 7304 model Vibrating Sample Magnetometer. In hemolytic activity tests, formation of a precipitate with a characteristic black color provided an explicit evidence to the formation of heme-iron complexes. Undesirable hemolytic effect of CoFe2O4 nanoparticles on human erythrocytes at both concentrations was attributed to the comparatively high amount of reactive oxygen species formed by CoFe2O4 nanoparticles. The theoretical concentration Co (theory) obtained by second-order model (0.82 mg/L) fit with the experimental value of Co (experimental) (0.95 mg/L) well in photocatalytic activity tests.

Magnetic and dielectric properties of BiFeO3 nanoparticles

2015 ◽  
Vol 7 (2) ◽  
pp. 1393-1403
Author(s):  
Dr R.P VIJAYALAKSHMI ◽  
N. Manjula ◽  
S. Ramu ◽  
Amaranatha Reddy
Keyword(s):  
Diffuse Reflectance Spectrum ◽  
Precipitation Method ◽  
Secondary Phases ◽  
X Ray Diffraction ◽  
Bifeo3 Nanoparticles ◽  
Transmission Electron ◽  
Multiferroic Bifeo3 ◽  
Pure Phase ◽  
Simple Chemical ◽  
Co Precipitation

Single crystalline nano-sized multiferroic BiFeO3 (BFO) powders were synthesized through simple chemical co-precipitation method using polyethylene glycol (PEG) as capping agent. We obtained pure phase BiFeO3 powder by controlling pHand calcination temperature. From X-ray diffraction studies the nanoparticles were unambiguously identified to have a rhombohedrally distorted perovskite structure belonging to the space group of R3c. No secondary phases were detected. It indicates single phase structure. EDX spectra indicated the appearance of three elements Bi, Fe, O in 1:1:3. From the UV-Vis diffuse reflectance spectrum, the absorption cut-off wavelength of the BFO sample is around 558nm corresponding to the energy band gap of 2.2 eV. The size (60-70 nm) and morphology of the nanoparticles have been analyzed using transmission electron microscopy (TEM).   Linear M−H behaviour and slight hysteresis at lower magnetic field is observed for BiFeO3 nanoparticles from Vibrating sample magnetometer studies. It indicates weak ferromagnetic behaviour at room temperature. From dielectric studies, the conductivity value is calculated from the relation s = L/RbA Sm-1 and it is around 7.2 x 10-9 S/m.

Microstructure Characterization of Metal Mixed Oxides

MRS Advances ◽  
2017 ◽  
Vol 2 (64) ◽  
pp. 4025-4030 ◽  
Author(s):  
T. Kryshtab ◽  
H. A. Calderon ◽  
A. Kryvko
Keyword(s):  
Mixed Oxides ◽  
Profile Analysis ◽  
Atomic Resolution ◽  
Precipitation Method ◽  
X Ray Diffraction ◽  
Reconstruction Procedure ◽  
Transmission Electron ◽  
Xrd Patterns ◽  
Co Precipitation

ABSTRACTThe microstructure of Ni-Mg-Al mixed oxides obtained by thermal decomposition of hydrotalcite-like compounds synthesized by a co-precipitation method has been studied by using X-ray diffraction (XRD) and atomic resolution transmission electron microscopy (TEM). XRD patterns revealed the formation of NixMg1-xO (x=0÷1), α-Al2O3 and traces of MgAl2O4 and NiAl2O4 phases. The peaks profile analysis indicated a small grain size, microdeformations and partial overlapping of peaks due to phases with different, but similar interplanar spacings. The microdeformations point out the presence of dislocations and the peaks shift associated with the presence of excess vacancies. The use of atomic resolution TEM made it possible to identify the phases, directly observe dislocations and demonstrate the vacancies excess. Atomic resolution TEM is achieved by applying an Exit Wave Reconstruction procedure with 40 low dose images taken at different defocus. The current results suggest that vacancies of metals are predominant in MgO (NiO) crystals and that vacancies of Oxygen are predominant in Al2O3 crystals.

Template Induced Synthesis of Nano-Hydroxyapatite by Co-Precipitation Method

2011 ◽  
Vol 311-313 ◽  
pp. 1713-1716 ◽  
Author(s):  
Yan Rong Sun ◽  
Tao Fan ◽  
Chang An Wang ◽  
Li Guo Ma ◽  
Feng Liu
Keyword(s):  
Electron Microscope ◽  
Chondroitin Sulfate ◽  
Aspartic Acid ◽  
Transmission Electron Microscope ◽  
Precipitation Method ◽  
X Ray Diffraction ◽  
X Ray ◽  
Structure And Morphology ◽  
Transmission Electron ◽  
Co Precipitation

Nano-hydroxyapatite with different morphology was synthesized by the co-precipitation method coupled with biomineralization using Ca(NO3)2•4H2O and (NH4)2HPO4 as reagents, adding chondroitin sulfate, agarose and aspartic acid as template. The structure and morphology of the prepared powders were characterized by X-ray diffraction (XRD) and transmission electron microscope (TEM).

Monodisperse Fe3O4/Fe Core/Shell Nanoparticles with Enhanced Magnetic Property

2011 ◽  
Vol 306-307 ◽  
pp. 410-415
Author(s):  
Li Sun ◽  
Fu Tian Liu ◽  
Qi Hui Jiang ◽  
Xiu Xiu Chen ◽  
Ping Yang
Keyword(s):  
Average Diameter ◽  
Chemical Precipitation ◽  
Precipitation Method ◽  
Core Shell ◽  
X Ray Diffraction ◽  
Shell Nanoparticles ◽  
X Ray ◽  
Transmission Electron ◽  
Shell Particles ◽  
Core Shell Nanoparticles

Core/shell type nanoparticles with an average diameter of 20nm were synthesized by chemical precipitation method. Firstly, Monodisperse Fe3O4 nanoparticles were synthesized by solvethermal method. FeSO4ž7H2O and NaBH4 were respectively dissolved in distilled water, then moderated Fe3O4 particles and surfactant(PVP) were ultrasonic dispersed into the FeSO4ž7H2O solution. The resulting solution was stirred 2 h at room temperature. Fe could be deposited on the surface of monodispersed Fe3O4 nanoparticles to form core-shell particles. The particles were characterized by using various experimental techniques, such as transmission electron microscopy (TEM), X-ray diffraction (XRD), AGM and DTA. The results suggest that the saturation magnetization of the nanocomposites is 100 emu/g. The composition of the samples show monodisperse and the sides of the core/shell nanoparticles are 20-30nm. It is noted that the formation of Fe3O4/Fe nanocomposites magnetite nanoparticles possess superparamagnetic property.

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