scholarly journals Clinical and epidemiological features of papillomavirus infection manifestations on the example of cervical cancer and genital warts

2020 ◽  
Vol 75 (1) ◽  
pp. 77-82 ◽  
Author(s):  
Nikolay I. Briko ◽  
Marina I. Sekacheva ◽  
Platon D. Lopukhov ◽  
Gleb S. Kobzev ◽  
Andrey D. Kaprin ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cervical Screening ◽  
Genital Warts ◽  
Hpv Infection ◽  
Epidemiological Features ◽  
Papillomavirus Infection ◽  
Significant Damage ◽  
Wide Range ◽  
Barrier Contraception ◽  
Epidemiological Characteristics

Background: Cervical cancer and genital warts (GWs) are some of the most common manifestations of human papillomavirus infection (HPV). These lesions cause significant damage to the reproductive health of the population, which leads to increased attention to the prevention of HPV infection among various population groups. Aims: To determine the clinical and epidemiological features of the HPV manifestations by the example of cervical cancer and genital warts. Methods: A retrospective analysis of anamnestic information of 115 women with an established diagnosis of cervical cancer and 177 patients with an established diagnosis of GWs was performed. The clinical and epidemiological characteristics of patients with diagnoses of GWs and cervical cancer were based on the development of outpatient admission cards and inpatient histories, as well as test data for HPV. Results: HPV 16 was the most common HPV type among patients with GWs and cervical cancer ― it was detected in 37.6% of cases. Also the most frequently encountered: HPV 6/18/11/31/51/52. In 43.2% cases of HPV detection, two or more types were detected at once, the most common combinations: HPV16 and HPV18, HPV6 and HPV16, HPV6 and HPV11. Analysis of the frequency of screening for cervical cancer and visits to the gynecologist for 5 years before establishing the diagnosis showed that among those who did not screen for cervical cancer, the risk of diagnosing stage IIIV was 5.2 times higher than among individuals who underwent cervical screening 2 years ago, or once a year for the last five years. Among patients with GWs who had 2 or more sexual partners for 1 year, 13.5% of patients regularly used barrier contraception methods (condoms) during sexual contact, not regularly ― 61.5%, did not use them at all ― 25.0%. Conclusions: Identifying the clinical and epidemiological features of HPV infection should contribute to the development of new and optimize existing prevention programs for a wide range of HPV-associated diseases.

scholarly journals Working towards a comprehensive understanding of HPV and cervical cancer among Indigenous women: a qualitative systematic review

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e050113
Author(s):  
Sneha Sethi ◽  
Brianna Poirier ◽  
Karen Canfell ◽  
Megan Smith ◽  
Gail Garvey ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Prevention ◽  
Ecological Model ◽  
Cervical Screening ◽  
Hpv Infection ◽  
Cervical Cancer Prevention ◽  
Social Ecological Model ◽  
Indigenous Women ◽  
Indigenous Populations ◽  
Social Ecological

RationaleIndigenous peoples carry a disproportionate burden of infectious diseases and cancers and are over-represented among the socially disadvantaged of most countries. Human papillomavirus (HPV) is a risk factor and causative agent of cervical, oropharyngeal and other cancers. Recent literature shows evidence of Indigenous populations being at increased risk of HPV infections and its associated cancers.ObjectiveThis is a qualitative systematic review. The objective of this study was to explore the experiences and barriers Indigenous women face in relation to HPV awareness, knowledge and cervical screening, in order to better understand factors that may mitigate against or facilitate prevention efforts for HPV infection and associated cancers.MethodsTwo investigators independently searched MEDLINE, PubMed, SCOPUS and Web of Science databases (for articles published from inception until 30 June 2020) using a prespecified search strategy to identify qualitative studies on narratives of Indigenous women regarding HPV infection awareness, knowledge and cervical screening, across all geographic and income-level settings. Using a ‘meta-study’ approach, a social ecological model of cervical screening, infection and associated cancer prevention among Indigenous populations was formulated.ResultsFive core themes were identified and formulated within the social ecological model; intrapersonal factors, interpersonal factors, institutional/organisational factors, sociocultural/community factors and public policy. These collectively formed the proposed social ecological model of HPV infection awareness and cervical cancer prevention among Indigenous women. This model has been synthesised by taking into account personal stories of Indigenous women and healthcare workers, thus offering a more nuanced, organised, structured and culturally sensitive approach to policy translation.ConclusionThe social ecological model of HPV infection awareness and cervical cancer prevention among Indigenous women offers a holistic and practical approach for Indigenous health policy makers. It clearly addresses the high risk of Indigenous populations at a global level in experience of both HPV infection and HPV-related cancers.PROSPERO registration numberCRD42020207643.

scholarly journals Intimate Stories: Aboriginal Women’s Lived Experiences of Health Services in Northern British Columbia and the Potential of Creative Arts to Raise Awareness About HPV, Cervical Cancer, and Screening

2013 ◽  
Vol 8 (1) ◽  
pp. 18 ◽  
Author(s):  
Virginia L. Russell ◽  
Sarah De Leeuw
Keyword(s):  
Cervical Cancer ◽  
British Columbia ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Health Care Services ◽  
Formal Education ◽  
Cervical Screening ◽  
Sexual Health Care ◽  
Wide Range ◽  
Screening Services

Guided by feminist and community-based participatory methodologies and by efforts to decolonize health research practices, and undertaken with qualitative research methods (interviews, open-ended questionnaires, and analysis of arts-based expressions like storytelling, journaling, and picture-making), this research identified challenges and barriers that (predominantly Aboriginal) women in northern British Columbia faced when trying to access sexual health care services related to HPV and cervical cancer screening. The research also examined the possible effectiveness of creative or arts-based strategies to promote cervical health and screening awareness among young and/or traditionally underserved or marginalized women. We review findings from data gathered over six months during multiple interactions with 22 women from a wide range of ethnic backgrounds. Results confirm that ethnicity, finances, and formal education are determinants in women’s awareness about, access to, and use of cervical screening services, and that experiences of gendered victimization, feelings of disempowerment, and life circumstances all influenced women’s comfort levels with, access to, and use of cervical cancer screening services.

Are Muslim women less susceptible to oncogenic human papillomavirus infection? A study from rural eastern India

2004 ◽  
Vol 14 (2) ◽  
pp. 293-303 ◽  
Author(s):  
C. Duttagupta ◽  
S. Sengupta ◽  
M. Roy ◽  
D. Sengupta ◽  
P. Bhattacharya ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Muslim Women ◽  
Epidemiological Data ◽  
Hpv Infection ◽  
Abnormal Cytology ◽  
Papillomavirus Infection ◽  
Atypical Cells ◽  
Hindu Women ◽  
Undetermined Significance

Muslim women are known to have lower incidences of cervical cancer and/or human papillomavirus (HPV) infection. Here we aim to determine any association that may be present between the oncogenic HPV16/18 infections and abnormal cytological lesions along with demographic and other attributes among Indian Muslim women (n = 478) and compare with the neighboring Hindus (n = 534) from a prospective cohort study. Agewise distribution of both subject-groups is similar. HPV16/18 infection is present in 9.6% Muslims and 7.5% Hindu women. Jointly atypical cells of undetermined significance (a typical cells of undetermined significance) and HPV16/18 are present in seven Muslim and two Hindu women. No high squamous intraepithelial lesions or cervical cancer is detected at the baseline. HPV16/18 infections show trends that varied with age, a nonlinear trend among Muslim women. In Hindu women the prevalence is highest at age ≤24 years, which linearly drops with increasing age. Abnormal cytology increases significantly in both religion-groups with increasing age. The data show that these Indian Muslim women are equally susceptible to HPV16/18 infection and for the development of abnormal cytology. There is a paucity in epidemiological data, which justifies the need to screen women of all religions for cervical cancer (that includes oncogenic HPV testing).

Risk factors associated with human papillomavirus infection status in a Korean cohort

2013 ◽  
Vol 142 (8) ◽  
pp. 1579-1589 ◽  
Author(s):  
H. LEE ◽  
D.-H. LEE ◽  
Y.-M. SONG ◽  
K. LEE ◽  
J. SUNG ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Contraceptive Use ◽  
Transmitted Disease ◽  
Multivariate Regression Analysis ◽  
Hpv Infection ◽  
Sexually Transmitted ◽  
Papillomavirus Infection ◽  
Behavioural Factors ◽  
Epidemiological Characteristics

SUMMARYBy surveying extensive epidemiological behavioural and sexual risk factors in a Korean twin cohort, risk factors for human papillomavirus (HPV) infection were investigated in South Korea. A total of 912 vaginal specimens were collected from the Healthy Twin Study, consisting of twins and their families. A range of epidemiological, behavioural, and sexual activity characteristics were evaluated using multivariate logistic regression analyses of family and twin relationships, adjusted to elucidate the risk factors for HPV infection. Of the various epidemiological characteristics, the possibility of extramarital affairs [odds ratio (OR) 2·48, 95% confidence interval (CI) 1·02–6·02] significantly increased the prevalence of HPV infection. Our multivariate regression analysis indicated that oral contraceptive use (OR 40·64, 95% CI 0·99–1670·7) and history of sexually transmitted disease (OR 2·56, 95% CI 0·93–7·10) were strongly associated with an increase in HPV infection. On the other hand, more frequent vaginal douching (OR 0·32, 95% CI 0·13–0·77) significantly decreased the prevalence of HPV infection. Our results suggested that HPV infection is associated with both biological and behavioural factors.

Australian women's needs and preferences for information about human papillomavirus in cervical screening

2005 ◽  
Vol 12 (3) ◽  
pp. 134-141 ◽  
Author(s):  
Kirsten McCaffery ◽  
Les Irwig
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Information Needs ◽  
Pap Smear ◽  
Cervical Screening ◽  
Hpv Infection ◽  
Sexual Partners ◽  
Policy And Practice ◽  
Management Options ◽  
Multiple Sexual Partners

Objective: The role of human papillomavirus (HPV) in cervical cancer and developments in medical technology to prevent cervical cancer has changed information needs for women participating in cervical screening. Design: Qualitative face-to-face interviews were conducted with 19 women diagnosed with HPV infection on their Pap smear following routine cervical screening. Setting: Family planning clinics, general practice and specialist gynaecologist practices in Sydney and the surrounding area, Australia. Main outcome measures: Women's information needs, preferences and experiences of HPV diagnosis. Results: Women wanted further information on different HPV viral types, transmission, implications for sexual partners, prevalence, latency and regression of HPV, their management options and the implications of infection for cancer risk and fertility. Uncertainty about the key aspects of HPV, the style in which the clinician communicated the result and the mode of delivering the result (letter, telephone or consultation) influenced women's psychological response to the diagnosis of HPV. The delivery of results by letter alone was linked to considerable anxiety among the women interviewed. Women's experience of searching the Internet for further information about HPV was reported as difficult, anxiety provoking and contributing to the stigma of the infection because information was often located in the context of other sexually transmitted infections, with multiple sexual partners highlighted as a risk factor for infection. Conclusion: Women participating in cervical screening need high-quality information about HPV and its role in cervical cancer prior to screening rather than afterwards, when they face an abnormal result. The clinician potentially plays an important role in moderating the effects of diagnosis through the manner and mode in which an HPV diagnosis is delivered. Revision of cervical screening policy and practice in light of the changes in the understanding of HPV is recommended.

scholarly journals Rural community’s perspectives on cervical cancer screening: Report of a consensus-planning workshop

2017 ◽  
Vol 3 (s1) ◽  
pp. 73
Author(s):  
Smita Asthana ◽  
Satyanarayana Labani
Keyword(s):  
Cervical Cancer ◽  
Rural Community ◽  
Rural Women ◽  
Elderly Women ◽  
Screening Programme ◽  
Cervical Screening ◽  
Community Setting ◽  
The Elderly ◽  
Hpv Infection ◽  
Using Data

<p>The success of any screening programme depends largely on the acceptability of the community to undergo screening. This study is an attempt to explore the perspectives of rural women on screening through qualitative research,<br />using data generated in a consensus workshop for an unscreened population prior to the start of a screening programme. The study adopted a qualitative method in the form of consensus-planning workshop prior to the start of the <em>care</em>HPV screening project. Knowledge about cervical cancer and human papillomavirus (HPV) infection was found to be very low. Special efforts are needed to educate the elderly women of the family and the peers of the rural community so that the project runs successfully, as their views can influence community participation. The response by rural women in undertaking selfsamplings was good. Cervical screening is acceptable and can be implemented in a rural community setting. The success of screening programme depends on health education of the rural community.</p>

scholarly journals Human papillomavirus infection and risk factors to cervical cancer in asymptomatic women in the region of the Northeast of Brazil

2021 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Karol Fireman de Farias ◽  
Adrielle Sonara Gomes Silva ◽  
Ana Caroline Melo dos Santos ◽  
Adriely Ferreira da Silva ◽  
Denise Macedo da Silva ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cervical Cancer ◽  
Oral Contraceptives ◽  
Hpv Infection ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Hpv Dna ◽  
Papillomavirus Infection ◽  
Behavioral Variables ◽  
Asymptomatic Women

Objective: This study sought to identify the presence of HPV infection and the risk factors related to susceptibility to cervical cancer in asymptomatic women. Methods: It is a cross-sectional study with 428 users attended Basic Health Units, in Arapiraca, Alagoas, Brazil. Sociodemographic, behavioral variables, and cytopathological reports were collected. Molecular detection of the HPV virus was performed by Nested-PCR. Statistical analysis was conducted with SPSS version 22.0. Results: A total of 428 women were studied, HPV DNA detected in 39.2% (n = 168), with a mean age of 41 years old. There was an association of HPV with use of oral contraceptives (p <0.016) and alcoholism (p <0.038). It was showed a higher frequency of positive HPV in women older than 25 years old (88.7%), up to 5 sexual partners (93.4%), up to 3 pregnancies (71.4%), and with the cytopathologic results within the limits of normality (61.9%). HPV was identified in 40.3% (104/258) of the women with results within the limits of normality. Conclusion: Our results suggest that the use of oral contraceptives and alcoholism may be considered as possible risk factors related to cervical oncogenesis. With this, it is necessary to propose interventions aimed at the health education of this population, actions of prevention, and early detection.

Human Papillomavirus Infection and Prevention In The Adolescent

2020 ◽  
Author(s):  
Alexandria Richards ◽  
Joanna Stacey
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccination ◽  
Transmitted Disease ◽  
Cervical Dysplasia ◽  
Vaccine Safety ◽  
Genital Warts ◽  
Hpv Infection ◽  
Sexually Transmitted ◽  
Papillomavirus Infection

Human papillomavirus, or HPV, is a common sexually transmitted disease, most often acquired during the adolescence or the early 20s. It can be divided into oncogenic and nononcogenic serotypes. It is responsible for genital warts as well as pathologic diseases that can lead to genital cancers and cancers of the oropharyngeal tract in both males and females. The majority of adolescents who acquire HPV infections do not go on to develop cancer. New discoveries about the virus’ persistence and latency direct how we treat adolescents with HPV infections. Recommendations for prevention of HPV include use of the 9-valent vaccine against the most common oncogenic HPV serotypes. Screening should be delayed until the age of 21, with the exception of immunocompromised women. The HPV vaccination is safe and effective, and does not encourage sexual activity among adolescents. Both boys and girls should be vaccinated against HPV at 11 to 12 years of age but may receive the vaccination as early as 9 or as late as 21 (males) or 26 (females) years of age. The vaccine may now also be given in only two doses if the series was started before the age of 15. Follow-up studies in the years after the vaccine’s introduction have shown large decreases in HPV infection rates. This review contains 7 figures, 7 tables and 63 references Key Words: Oncogenic subtype, Oropharyngeal cancer, Infection persistence, Immune tolerance, Cervical dysplasia, Genital warts, 9-valent vaccine, Vaccine safety  

scholarly journals Unresolved questions concerning human papillomavirus infection and transmission: a modelling perspective

Sexual Health ◽  
2010 ◽  
Vol 7 (3) ◽  
pp. 368 ◽  
Author(s):  
David G. Regan ◽  
David J. Philp ◽  
Edward K. Waters
Keyword(s):  
Cervical Cancer ◽  
Health Policy ◽  
Human Papillomavirus ◽  
Hpv Infection ◽  
Acquired Immunity ◽  
Knowledge Gaps ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Potential Impact ◽  
Transmission Models

Mathematical transmission models are widely used to forecast the potential impact of interventions such as vaccination and to inform the development of health policy. Effective vaccines are now available for the prevention of cervical cancer and other diseases attributable to human papillomavirus (HPV). Considerable uncertainties remain regarding the characterisation of HPV infection and its sequelae, infectivity, and both vaccine-conferred and naturally-acquired immunity. In this review, we discuss the key knowledge gaps that impact on our ability to develop accurate models of HPV transmission and vaccination.

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