Left ventricular thickness may be affected by higher arterial blood pressure and body-mass index in asymptomatic adolescents

Abstract Background: The use of contraceptives has become prevalent among women in Ethiopia. Oral contraceptive use has been suggested to trigger changes in glucose metabolism, energy expenditure, blood pressure, and body weight, among the various populations and ethnic groups. Objective: To elucidate the pattern of fasting blood sugar (FBS), blood pressure and body mass index (BMI) among combined oral contraceptive (COC) pills users, taking into account other confounding factors including socioeconomic conditions and physical activity status. Methods: An institution based cross-sectional study design was employed. A total of 110 healthy women using pills were recruited as cases. Another 110 healthy women not using any hormonal contraceptives were recruited as matched controls. A study was conducted between October 2018 and January 2019. Fasting Capillary blood sample was collected from the study participants for the estimation of the FBS level. Systolic and diastolic blood pressures were measured and means arterial blood pressure was calculated for each participant. Body weight and height were measured to compute body mass index. Data obtained was entered and analyzed using IBM SPSS version 23 software packages. Results: FBS level in users was significantly increased compared to controls (88.55 ± 7.89 vs. 86.00 ± 9.85 in users and controls respectively, P = 0.025). There was a significant difference in mean arterial blood pressure of users compared to controls (88.2 ± 8.48 vs. 86.0 ± 6.74 respectively, P=0.04). The mean weight and body mass index of users were significantly increased (P = 0.03 and P = 0.003, respectively). Changes in mean fasting blood sugar level and mean weight of users were independent (P = 0.27 and P = 0.46) to the duration of use (3-12, 13-24 and ≥ 25 months). On the other hand, changes in mean body mass index and mean arterial blood pressure of users were dependent of the duration of use (P = 0.03 and P = 0.000 respectively). Conclusions: Overall, oral contraceptive pills use appears to cause a 2.9% increase in fasting blood glucose level, a 2.5% increase in mean arterial blood pressure and a 3.9% increase in body mass index among the users.

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Platelet count, mean platelet volume and size distribution in relation to arterial blood pressure, age, smoking habits and body mass index

Fibrinolysis and Proteolysis ◽

10.1016/0268-9499(90)90284-q ◽

1990 ◽

Vol 4 ◽

pp. 102

Author(s):

U. Harbrecht ◽

B. Graulich ◽

R. Düsing

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Platelet Count ◽

Size Distribution ◽

Arterial Blood Pressure ◽

Body Mass ◽

Mean Platelet Volume ◽

Smoking Habits ◽

Platelet Volume ◽

Arterial Blood

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Five-Year Change in Intraocular Pressure Associated with Changes in Arterial Blood Pressure and Body Mass Index. The Beijing Eye Study

PLoS ONE ◽

10.1371/journal.pone.0077180 ◽

2013 ◽

Vol 8 (10) ◽

pp. e77180 ◽

Cited By ~ 17

Author(s):

Ya Xing Wang ◽

Liang Xu ◽

Xiao Hui Zhang ◽

Qi Sheng You ◽

Liang Zhao ◽

...

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Intraocular Pressure ◽

Arterial Blood Pressure ◽

Body Mass ◽

Beijing Eye Study ◽

Arterial Blood

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Relation among Left Ventricular Mass, Insulin Resistance, and Blood Pressure in Nonobese Subjects1

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jcem.83.12.5331 ◽

1998 ◽

Vol 83 (12) ◽

pp. 4284-4288

Author(s):

Robert A. Phillips ◽

Lawrence R. Krakoff ◽

Andrea Dunaif ◽

Diane T. Finegood ◽

Richard Gorlin ◽

...

Keyword(s):

Insulin Resistance ◽

Blood Pressure ◽

Body Mass Index ◽

Insulin Sensitivity ◽

Body Mass ◽

Tolerance Test ◽

Left Ventricular ◽

Sensitivity Index ◽

Consecutive Series ◽

Arterial Blood

Because left ventricular (LV) mass (LVM) is a powerful predictor of future cardiovascular events, it is important to identify hemodynamic and nonhemodynamic factors that increase LVM. We studied the separate contribution to LVM of daily arterial blood pressure (BP) and insulin resistance in a consecutive series of 29 (mean ± sd age, 43 ± 13 yr) nonobese (body mass index, 24 ± 1.8 kg/m2), nondiabetic, glucose-tolerant subjects with untreated borderline or mild hypertension. The insulin sensitivity index (SI) was quantitatively determined from the frequently sampled iv glucose tolerance test. BP was characterized by ambulatory 24-h BP monitoring, and LVM index (LVMI) was determined by two-dimensional directed M-mode echocardiography. LVMI was directly related to 24-h mean BP (r = 0.47; P = 0.01). LMVI was also significantly related to SI (r = −0.43; P = 0.02). In this nonobese group, neither LVMI nor SI was related to body mass index or age. After adjustment for the influence of BP on LVMI, a significant relation remained between LVMI and SI (P < 0.05). We conclude that in nonobese subjects with high normal BP, insulin sensitivity is related to LVM independently of BP and may be an important modulator of LV growth. In addition to a reduction of arterial BP, optimal prevention of LV hypertrophy in hypertensives may require improved insulin sensitivity.

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Ageing, Arterial Blood Pressure, Body Mass Index, and Diet

Archives of Industrial Hygiene and Toxicology ◽

10.2478/10004-1254-63-2012-2164 ◽

2012 ◽

Vol 63 (Supplement-1) ◽

pp. 3-9 ◽

Cited By ~ 3

Author(s):

Mladen Pavlović ◽

Sanja Milković-Kraus ◽

Veljko Jovanović ◽

Mira Hercigonja-Szekeres

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Arterial Blood Pressure ◽

Body Mass ◽

Healthy Aging ◽

Linear Models ◽

Dietary Habits ◽

Arterial Blood ◽

Log Linear

Ageing, Arterial Blood Pressure, Body Mass Index, and Diet For three decades we followed up for longevity indicators, including diet, arterial blood pressure, and body mass index 379 mobile, long-living persons from Croatia, now aged 70 to 92 years, of whom 167 men aged (78.6±4.0) years and 212 women aged (77.9±4.1) years. One hundred and ninety-five were from the continental and 184 from the coastal Croatia. The participants were examined in 1972, 1982, and again in 2006/7. Changes in body mass index (BMI), arterial blood pressure (ABP), and in answers to our Food Frequency Questionnaire about dietary habits were analysed using log-linear models. Over the last 24 years of aging (age 55 to 78 years) the subjects showed a statistically significant decrease in body mass and height and a significant increase in the systolic blood pressure. Diastolic blood pressure and BMI showed no significant changes over this period. Consumption of preserved and fresh meat, bread, and starch (potato, pastry and rice) dropped significantly with age, while the consumption of fish, fresh and cooked vegetables, fruit, and dairy products significantly increased. These dietary changes were not associated with changes in the systolic and diastolic ABP. About 80 % were overweight (BMI >25 kg m-2) throughout the follow-up, even though their body mass dropped significantly after the age of 55. However, their survival suggests that BMI may not be the best indicator of longevity or healthy aging.

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