scholarly journals Prevalence of metabolic components in university students

2014 ◽  
Vol 22 (6) ◽  
pp. 1041-1047 ◽  
Author(s):  
Ana Roberta Vilarouca da Silva ◽  
Luana Savana Nascimento de Sousa ◽  
Telma de Sousa Rocha ◽  
Ramiro Marx Alves Cortez ◽  
Layla Gonçalves do Nascimento Macêdo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Fasting Blood Glucose ◽  
Significant Proportion ◽  
Hdl Cholesterol ◽  
Clinical Analysis ◽  
Abdominal Circumference ◽  
Sample Collection ◽  
Glucose Levels ◽  
Low Hdl

OBJECTIVE: to identify the frequency of components of Metabolic Syndrome (MetS) among university students.METHOD: descriptive study with 550 students, from various courses run by a public university. The socioeconomic data, lifestyle, and components of MetS were filled out using a questionnaire. Blood sample collection was undertaken in the university itself by a contracted clinical analysis laboratory.RESULTS: 66.2% were female, with a mean age of 22.6±4.41; 71.7% were sedentary; 1.8% stated that they smoke; and 48.5% were classified as at medium risk for alcoholism. 5.8% had raised abdominal circumference and 20.4% had excess weight; 1.3% and 18.9% had raised fasting blood glucose levels and triglycerides, respectively; 64.5% had low HDL cholesterol and 8.7% had blood pressure levels compatible with borderline high blood pressure. Thus, of the sample, 64.4% had at least one component for MetS; 11.6% had two, and 3.5% had three or more.CONCLUSION: a significant proportion of the population already has the components for metabolic syndrome, and this profile reinforces the importance of early diagnosis so as to reduce the risk of developing chronic comorbidities.

scholarly journals Heritability of the metabolic syndrome and its components in the Tehran Lipid and Glucose Study (TLGS)

2012 ◽  
Vol 94 (6) ◽  
pp. 331-337 ◽  
Author(s):  
MARYAM ZARKESH ◽  
MARYAM SADAT DANESHPOUR ◽  
BITA FAAM ◽  
MOHAMMAD SADEGH FALLAH ◽  
NIMA HOSSEINZADEH ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Hdl Cholesterol ◽  
Age And Gender ◽  
The Metabolic Syndrome ◽  
Biological Parents ◽  
Heritability Estimation ◽  
Low Hdl ◽  
And Gender ◽  
Continuous Traits

SummaryGrowing evidence suggests that metabolic syndrome (MetS) has both genetic and environmental bases. We estimated the heritability of the MetS and its components in the families from the Tehran Lipid and Glucose Study (TLGS). We investigated 904 nuclear families in TLGS with two biological parents and at least one offspring (1565 parents and 2448 children), aged 3–90 years, for whom MetS information was available and had at least two members of family with MetS. Variance component methods were used to estimate age and sex adjusted heritability of metabolic syndrome score (MSS) and MetS components using SOLAR software. The heritability of waist circumference (WC), HDL-cholesterol (HDL-C), triglycerides (TGs), fasting blood sugar (FBS), systolic blood pressure (SBP) and diastolic blood pressure (DBP) as continuous traits after adjusting for age and gender were 27, 46, 36, 29, 25, 26 and 15%, respectively, and MSS had a heritability of 15%. When MetS components were analysed as discrete traits, the estimates of age and gender adjusted heritability for MetS, abdominal obesity, low HDL-C, high TG, high FBS and high blood pressure (BP) were 22, 40, 34, 38 and 23%, respectively (P < 0·05). Three factors were extracted from the six continuous traits of the MetS including factor I (BP), factor II (lipids) and factor III (obesity and FBS). Heritability estimation for these three factors were 7, 13 (P < 0·05) and 2%, respectively. The highest heritability was for HDL-C and TG. The results strongly encourage efforts to identify the underlying susceptibility genes.

scholarly journals Metabolic characteristics and nutrition intake on women with normal body mass index

Food Research ◽  
2020 ◽  
Vol 4 (S3) ◽  
pp. 6-12
Author(s):  
D.Y. Fitranti ◽  
F.F. Dieny ◽  
D.M. Kurniawati ◽  
R. Purwanti ◽  
B. Kusumaningnastiti ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Hdl Cholesterol ◽  
Normal Weight ◽  
Normal Body Mass Index ◽  
Metabolic Characteristics ◽  
Low Hdl ◽  
Nutrition Intake

Metabolic syndrome can be found on an individual with normal weight (Metabolically Obese Normal Weight/MONW). Eating habits and lifestyle changing in early adulthood can be the risk of metabolic syndrome in person with a normal body mass index (BMI). The purpose of this study was to identify metabolic characteristics in women with normal BMI and to analyze the correlation of nutrition intake with metabolic syndrome on women with normal BMI. This is an observational study with a cross-sectional design at five offices in Semarang. The sample in this study was 64 subjects. Inclusion criteria of study subject were women aged 25-40 years and BMI <25 kg/m2 . Study subject was chosen by using a consecutive sampling method. The data of nutrition intake was obtained by using the Food Frequency Questionnaire. HDL cholesterol, fasting blood glucose and triglyceride were analyzed. Analysis data was conducted by using Pearson correlation and Rank Spearman. MONW was present in 10.9% and more than 50% had pre metabolic syndrome. A total of 51.6% of the subjects had central obese and 26.6% had low HDL cholesterol. About 14.1% of the subjects have hypertension. There was a positive correlation between energy, fat intake and waist circumference. Carbohydrate intake was positively correlated with fasting blood glucose and triglyceride. The higher protein intake, the higher HDL cholesterol. The most common indicator of metabolic syndrome on women with normal BMI was central obesity and low HDL cholesterol. The factors related to the prevalence of metabolic syndrome on women with normal BMI was macronutrient intake.

Abstract MP19: Higher Parity is Associated With Components of the Metabolic Syndrome Among U.S. Hispanic/Latina Women: Results From the HCHS/SOL Study

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Catherine J Vladutiu ◽  
Anna Maria Siega-Riz ◽  
Alison M Stuebe ◽  
Daniela Sotres-Alvarez ◽  
Andy Ni ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Hispanic Women ◽  
Hdl Cholesterol ◽  
Latina Women ◽  
Live Births ◽  
The Metabolic Syndrome ◽  
Elevated Glucose ◽  
Low Hdl

Background: Physiologic adaptations occurring across successive pregnancies may increase the risk of adverse cardiovascular health outcomes in later life. Previous studies have found an association between higher parity and the metabolic syndrome (MetS). However, no studies have examined this association in a Hispanic/Latina population. Hispanic women have a higher prevalence of the MetS and higher birth rates than non-Hispanic women. Hypothesis: We assessed the hypothesis that higher parity is associated with the prevalence of components of the MetS in a cohort of Hispanic/Latina women. Methods: There were 9,482 Hispanic/Latina women of diverse backgrounds, aged 18-74 years, who participated in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) from 2008-2011. Components of the MetS were defined according to the AHA/NHLBI criteria and included abdominal obesity (waist circumference ≥88cm), elevated triglycerides (≥150 mg/dL), low HDL cholesterol (<50mg/dL), high blood pressure (systolic ≥130mmHg or diastolic ≥85mmHg or on medication), and elevated fasting glucose (≥100mg/dL or on medication). Logistic regression models were used to estimate odds ratios for the association between parity and components of the MetS, adjusting for sociodemographic, behavioral, and reproductive characteristics, and accounting for the complex survey design and sampling weights. Results: At HCHS/SOL baseline, women reported none (19.2%), one (18.9%), two (25.3%), three (19.7%), four (9.3%), and five or more (7.6%) prior live births. Compared to women with only one live birth, women with four live births had the highest odds of abdominal obesity (OR=2.5, 95% CI 1.8, 3.3) and those with five or more live births had the highest odds of low HDL cholesterol (OR=1.5, 95% CI 1.2, 1.9), elevated glucose (OR=1.8, 95% CI 1.3, 2.3), elevated triglycerides (OR=1.4, 95% CI 1.01, 1.8), and high blood pressure (OR=1.5, 95% CI 1.1, 2.0), after adjusting for age, Hispanic background, education, marital status, income, nativity, smoking, physical activity, menopause status, oral contraceptive use, hormone replacement therapy, and field center. Further adjustment for body mass index attenuated these associations for all MetS components, including abdominal obesity (OR=1.5, 95% CI 1.1, 2.2), low HDL cholesterol (OR=1.3, 95% CI 1.03, 1.7), and elevated glucose (OR=1.6, 95% CI 1.2, 2.1), but the associations for triglycerides and blood pressure were no longer statistically significant. Conclusion: Higher parity is associated with the prevalence of selected components of the MetS among U.S. Hispanic/Latina women. High parity among Latinas with a high prevalence of abdominal obesity suggests a context of high risk for metabolic dysregulation. A better characterization of the links between pregnancy, adiposity, and body fat distribution is needed.

scholarly journals Association of normoalbuminuria and microalbuminuria with the components of metabolic syndrome in Bangladeshi adults

2020 ◽  
Vol 10 (3) ◽  
pp. 152-158
Author(s):  
Muntakim Mahmud Saadi ◽  
Farida Akhter Tania ◽  
Manindra Nath Roy ◽  
Rubena Haque ◽  
Farzana Akonjee Mishu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Blood Glucose ◽  
Urinary Albumin Excretion ◽  
Fasting Blood Glucose ◽  
Urinary Albumin ◽  
Normal Range ◽  
Low Hdl

Background: Metabolic syndrome (MetS) is clustering of metabolic abnormalities characterized by obesity, hypertension, dyslipidemia and glucose intolerance that collectively increases the risk of diabetes mellitus, cardiovascular disease, stroke and overall mortality. Microalbuminuria is associated with diabetes mellitus, hypertention, obesity all are components of metabolic syndrome. Microalbuminuria and MetS have both been linked to chronic kidney disease and cardiovascular disease. Before development of microalbuminuria there is a wide normal range for urinary albumin excretion. By comparing the strength of the association between MetS and its components with normoalbuminuria and microalbuminuria, we can assess the risk of cardiovascular and renal diseases. This study aimed to evaluate the association of normoalbuminuria and microalbuminuria with the components of MetS in Bangladeshi adult subjects. Methods: It was a cross-sectional analytical study, carried out in the Department of Biochemistry of Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh during the period of March 2017 to January 2018. Total 175 patients with MetS attending the outpatient department of Medicine and Endocrinology of Mitford Hospital were included. Collected data was checked, edited and analyzed with the help of software SPSS (Statistical Package for Social Sciences) version 22. Results: This study showed, among the total 175 study subjects, 125 subjects were with normoalbuminuria (71.43%) and 50 subjects had microalbuminuria (28.57%). With an average age 42.4 years, female were 52% in this study. There was also female predominance among microalbuminuric subjects (13.71% vs 14.75%). Participants with microalbuminuria were more likely to have higher systolic blood pressure (SBP), diastolic blood pressure (DBP) and fasting blood glucose (FBG) than those with normoalbuminuria. The albumin creatinine ratio (ACR) of study subjects ranged from 3.00 to 270.39 mg/g and mean ACR was 27.14 mg/g. The mean ACR for participants with three (n=34), four (n=72) and five (n=69) components of MetS were 14.73, 19.94 and 40.77 mg/g respectively and corresponding prevalence of microalbuminuria was 10%, 32% and 58% respectively. Normal range of urinary albumin excretion rate (normoalbuminuria) were classified into four quartiles according to their ACR values and ranges for Q1, Q2, Q3 & Q4 were respectively Q1 = 3.00 to 5.1, Q2 = 5.1 to 8.2, Q3 = 8.2 to 13.89, Q4 = 13.89 to 28.1mg/g. The means of elevated DBP, SBP, FBG and tri-acyl glycerol (TAG) among the components of MetS showed increasing trend from lower to upper quartiles within normal range. Q1 was considered as base line in comparison to other quartiles. Odds of elevated WC, FBG, TAG, BP and low HDL-C were high across increasing quartiles of ACR (1.00 vs 1.33 vs 2.24 vs 1.79 respectively for central obesity; 1.00 vs 1.07 vs 1.97 vs 2.07 respectively for elevated fasting blood glucose; 1.00 vs 1.51 vs 1.69 vs 1.69 respectively for elevated TAG; 1.00 vs 6.86 vs 3.87 vs 2.88 respectively for elevated BP and 1.00 vs 1.35 vs 2.79 vs 2.79 respectively for low HDL-C; p-values <0.05 for all). Among the components of MetS, most significant relationship was observed between elevated BP and increasing ACR quartile within normal range. Conclusions: In conclusion, we demonstrated that microalbuminuria was strongly associated with MetS and its components. Microalbuminuria should be reconsidered as a component of MetS as it shows incremental effect with severity of MetS. Even upper normal range of albuminuria (higher normoalbuminuria) is strongly associated with elevated BP, FBG and TAG among the components of MetS. So, normal range of albuminuria should be rearranged after performing large scale population study in this regard. Birdem Med J 2020; 10(3): 152-158

scholarly journals HUBUNGAN KUALITAS TIDUR DENGAN 5 INDIKATOR SINDROMA METABOLIK PADA PERAWAT DI RUMAH SAKIT UMUM PUSAT HAJI ADAM MALIK MEDAN

2021 ◽  
Vol 20 (2) ◽  
Author(s):  
Simon Simon
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Blood Glucose ◽  
Sleep Quality ◽  
Fasting Blood Glucose ◽  
Hdl Cholesterol ◽  
T Test ◽  
Human Beings ◽  
Glucose Content ◽  
Significant Difference

 ABSTRACTHigh death rate caused by non-transmitted diseases in the world is begun with metabolic syndrome in human beings such the increase in IMT (Body Mass Index) to be obesity, the increase in blood pressure to be hypertension, the increase in blood glucose to be diabetes mellitus, and abnormality of triglycerides, and  HDL cholesterol. Many factors which trigger the indicator abnormality, and of them is bad sleep quality. The research used cross sectional design by analyzing the correlation between sleep quality and 5 metabolic syndrome indicator in female nurses in the operation room of Adam Malik Medan hospital. Sleep quality was measured by using questionnaire of Pittsburg Sleep Quality Index (PSQI), body height and weight were measured to get IMT value, blood pressure was measured by using tensimeter, blood glucose and blood lipid were measured by getting the respondent’s vena blood samples. The data were processed and analysis with independent t-test.The result with independent t-test showed that there was significant difference in IMT (sig=0,003), systolic blood pressure (sig=0,028), and fasting blood glucose content (sig=0,00). However, there was no significant difference in trigliyceride content (sig=0,519), HDL cholesterol content (sig=0,300),). The conclusion was that sleep quality was correlated with three metabolic syndrome indicators: IMT, blood pressure, and blood glucose content, but there was no correlation with trigliyceride and HDL cholesterol.Keywords: Sleep Quality, Metabolic Syndrome , T-Test, 

Physiological and Therapeutic Outcomes of Intermittent Fasting versus Calorie-Restriction Diet in Patients suffering from Metabolic Syndrome

2019 ◽  
Vol 3 (1) ◽  
pp. 4-19
Author(s):  
Doreen Susanne Micallef
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Weight Loss ◽  
Blood Glucose ◽  
Calorie Restriction ◽  
Fasting Blood Glucose ◽  
Hdl Cholesterol ◽  
Intermittent Fasting ◽  
Retrospective Case ◽  
Restriction Diet

The main objective of this study was to determine whether an intermittent fasting diet in combination with a CR diet results in better outcomes on risk factors associated with metabolic syndrome (such as lowering of triglycerides, fasting blood glucose, and blood pressure decrease in abdominal obesity and an increase in HDL-cholesterol and related weight loss for both male and female patients) than with a conventional CR diet alone. A 12-week retrospective case-control study was carried out and involved 78 females and 22 males who exhibited or were receiving medications for three or more conditions related to metabolic syndrome and who completed the study out of 120 participants at baseline. These were randomly assigned to either a conventional calorie-restriction diet or to an intermittent-fasting diet. Relevant baseline parameters were measured during the first encounter and were then repeated after twelve weeks. Professional contact was maintained on a fortnightly basis for both groups. Subjects randomly assigned to the intermittent fasting diet lost more weight than subjects on a conventional calorie-restriction diet after 12 weeks (mean ± SD, 5.7 ± 3.2 kg vs 11.4 ± 6.4 kg; p < 0.001). There were also statistically significant decreases in waist circumference (10.1 ± 7.2 cm vs 4.5 ± 3.3 cm; p < 0.001), serum triglycerides (0.31 ± 0.29 mmol/l vs 0.16 ± 0.16 mmol/l; p = 0.002), and systolic blood pressure (11.1 ± 8.2 mm Hg vs 5.2 ± 4.8 mm Hg; p < 0.001) and an increase in HDL-cholesterol (0.25 ± 0.16 vs 0.14 ± 0.15 mmol/l; p = 0.001). However, no statistically significant changes in diastolic blood pressure and fasting blood glucose were recorded. The intermittent fasting diet gave better weight loss outcomes (6.67% vs 12.35%) than did the conventional calorie restriction diet when compared to the baseline weight after the conclusion of the 12-week programme. The intermittent fasting diet was also associated with statistically significant improvements in four out of the six parameters measured and associated with metabolic syndrome. Longer-term studies are required to determine whether these outcomes will be maintained over longer periods of time assuming that there is compliance by the participants.

scholarly journals Association between 24 h urinary sodium and potassium excretion and the metabolic syndrome in Chinese adults: the Shandong and Ministry of Health Action on Salt and Hypertension (SMASH) study

2015 ◽  
Vol 113 (6) ◽  
pp. 996-1002 ◽  
Author(s):  
Zeng Ge ◽  
Xiaolei Guo ◽  
Xiaorong Chen ◽  
Junli Tang ◽  
Liuxia Yan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Central Obesity ◽  
Hdl Cholesterol ◽  
Elevated Blood Pressure ◽  
Potassium Excretion ◽  
Elevated Blood ◽  
Chinese Adults ◽  
The Metabolic Syndrome ◽  
Low Hdl

The association of 24 h urinary Na and potassium excretion with the risk of the metabolic syndrome (MetS) has not been studied in China. The aim of the present study was to examine this association by analysing the data from 1906 study participants living in north China. To this end, 24 h urine samples were collected. Of the 1906 participants, 471 (24·7 %) had the MetS. The mean urinary Na and K excretion was 228·7 and 40·8 mmol/d, respectively. After multivariate adjustment, the odds of the MetS significantly increased across the increasing tertiles of urinary Na excretion (1·00, 1·40 and 1·54, respectively). For the components of the MetS, the odds of central obesity, elevated blood pressure and elevated TAG, but not the odds of low HDL-cholesterol and elevated fasting glucose, significantly increased with the successive tertiles of urinary Na excretion. Furthermore, for every 100 mmol/d increase in urinary Na excretion, the odds of the MetS, central obesity, elevated blood pressure and elevated TAG was significantly increased by 29, 63, 22 and 21 %, respectively. However, urinary K excretion was not significantly associated with the risk of the MetS. These findings suggest that high Na intake might be an important risk factor for the MetS in Chinese adults.

scholarly journals The Prevalence of Metabolic Syndrome in the Different Phenotypes of Polycystic Ovarian Syndrome

2019 ◽  
Vol 41 (01) ◽  
pp. 037-043 ◽  
Author(s):  
Aleide Tavares ◽  
Romualda Rêgo Barros
Keyword(s):  
Metabolic Syndrome ◽  
Polycystic Ovarian Syndrome ◽  
Fasting Blood Glucose ◽  
Serum Triglyceride ◽  
Hdl Cholesterol ◽  
Abdominal Circumference ◽  
Polycystic Ovaries ◽  
Ovulatory Dysfunction ◽  
Significant Difference ◽  
Ovarian Syndrome

Objective To evaluate the prevalence of metabolic syndrome (MetS) in the phenotypes of polycystic ovarian syndrome (PCOS). Methods This was a cross-sectional study involving 111 women aged between 18 and 39 years old diagnosed with PCOS, according to the Rotterdam Criteria, and grouped into four phenotypes: A: ovulatory dysfunction + hyperandrogenism + polycystic ovaries; B: ovulatory dysfunction + hyperandrogenism; C: hyperandrogenism + polycystic ovaries; D: ovulatory dysfunction + polycystic ovaries. To evaluate the presence of MetS, we measured serum triglyceride levels, HDL cholesterol, fasting blood glucose, blood pressure, and waist circumference. Results The prevalence of MetS found in this sample was 33.6%, and there was no statistically significant difference (p < 0.05) among the 4 phenotypes. However, phenotype D presented a significantly higher mean glucose level after fasting (93.6 mg/dL) and 2 hours after ingesting a solution with 75 g of anhydrous glucose (120 mg/dL), as well as the lowest mean level of high-density lipoprotein (HDL) cholesterol (44.7 mg/dL). The women in this group demonstrated a high prevalence of abdominal circumference ≥ 80 cm (68.2%), as well as the highest mean abdominal circumference (90.1 cm). Amongst the women with an abdominal circumference ≥ 80 cm, phenotype A increased approximately six-fold the chance of developing metabolic syndrome in relation to phenotype C. Conclusion The four phenotypes of PCOS demonstrated similar prevalence rates of metabolic syndrome; abdominal obesity presented a relevant role in the development of metabolic alterations, regardless of the phenotype.

scholarly journals Waist:height ratio, waist circumference and metabolic syndrome abnormalities in Colombian schooled adolescents: a multivariate analysis considering located adiposity

2015 ◽  
Vol 114 (5) ◽  
pp. 700-705 ◽  
Author(s):  
Ricardo Antonio Agredo-Zúñiga ◽  
Cecilia Aguilar-de Plata ◽  
Milton Fabian Suárez-Ortegón
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Cardiometabolic Risk ◽  
Subcutaneous Fat ◽  
Prevalence Ratio ◽  
Hdl Cholesterol ◽  
Female Adolescents ◽  
Low Hdl ◽  
High Fasting Glucose

Very few large studies in Latin America have evaluated the association between waist:height ratio (W-HtR) and cardiometabolic risk in children and adolescents. Further, multivariable analyses verifying the independence of located subcutaneous fat have not been conducted so far. The aim of this study was to evaluate the associations of W-HtR and waist circumference (WC) with metabolic syndrome abnormalities and high LDL-cholesterol levels in schooled adolescents before and after adjusting for trunk skinfolds and BMI. The sample consisted of 831 boys and 841 girls aged 10–17 years. Biochemical, blood pressure and anthropometrical variables were measured. Age- and sex-specific quartiles of W-HtR and WC were used in Poisson regression models to evaluate the associations. High WC values (highest quartilev. quartiles 1–3) were associated with high TAG levels in both sexes (prevalence ratio, boys: 2·57 (95 % CI 1·91, 3·44); girls: 1·92 (95 % CI 1·49, 2·47);P<0·05), and with high blood pressure specifically in female adolescents (3·07 (95 % CI 1·58, 5·98);P<0·05), independently of trunk skinfolds or BMI (P<0·05). Associations of high WC with high fasting glucose (boys), low HDL-cholesterol and having at least two abnormalities did not remain significant in most of the adjustments for trunk skinfolds or BMI (P>0·05). High W-HtR (highest quartilev. quartiles 1–3) was only independently associated with high TAG in female adolescents (1·99 (95 % CI 1·55, 2·56);P<0·05). In conclusion, WC showed better association with cardiometabolic risk than W-HtR in the children of this study. This observation does not support W-HtR as a relevant adiposity marker for cardiovascular and metabolic risk in adolescence.

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