scholarly journals PHOSPHOCREATINE IMPROVES MUSCLE MICROCIRCULATION DURING EXERCISE

2021 ◽  
Vol 27 (8) ◽  
pp. 770-772
Author(s):  
Lei Ma

ABSTRACT Introduction: Phosphate (CP) its biosynthesis begins with the kidney. Glycocianine was synthesized from glycocianine, then methylated in the liver, and finally formed in each tissue. Objective: To study the effects of phosphatic acid in exercise training. Methods: This paper uses 50 pure male mice, 2 month old, weight at 22 ± 3 g, and mice per day, 5 minutes each time. After exercise training, dry dry with a towel and blow it with a hair dryer, and move it to the end of each other. Results: The average time of motion B mouse to give phosphate creatine is significantly longer than the average time of the non-administration of the A group, and the motion time is prolonged to extend 23.20%. Phosphate has improved motor endurance and promotes improvement in muscle microcirculation during exercise. Conclusions: Motion can be used to improve the maximum aerobic capacity of exercise in motion. Level of evidence II; Therapeutic studies - investigation of treatment results.

2021 ◽  
Vol 27 (7) ◽  
pp. 670-673
Author(s):  
Guohai Zhou

ABSTRACT Introduction: There have been many reports on athletes’ cardiovascular function, but there are very few methods used to evaluate the case. Objective: This article studies the relationship between sports fatigue and the cardiovascular response of athletes so that athletes can exercise and train more scientifically and safely. Methods: The paper selected some national athletes from 2017 to 2020 to carry out the VO2max, step test, YoYo test, 12-minute running, and other tests related to the cardiovascular function. Results: Athletes can promote the improvement of their cardiovascular function when they perform aerobic exercise training. Conclusion: Public physical education and amateur physical training should focus on the development of aerobic endurance. This can improve athletes’ cardiovascular function. Level of evidence II; Therapeutic studies - investigation of treatment results.


2019 ◽  
Vol 25 (2) ◽  
pp. 137-141 ◽  
Author(s):  
Emy Suelen Pereira ◽  
Walter Krause Neto ◽  
Atilio Sersun Calefi ◽  
Mariana Georgetti ◽  
Larissa Guerreiro ◽  
...  

ABSTRACT Introduction: The search for strategies aimed at reducing daily stress is increasing in the current literature. As a result, several types of fitness training are constantly being investigated for their influence on mood states. However, we know little about strategies that use higher intensities. Objective: To investigate the acute effects of an extreme conditioning training (ECT) session on the mood states of individuals with or without prior experience in this type of training. Methods: Volunteers were divided into TRAINED (n = 10) and CONDITIONED (n = 10) groups, undergoing a single 9-minute ECT session. Mood states (BRUMS scale) were analyzed at baseline, immediately afterwards, and after 30 minutes. Results: Anger, confusion and tension were significantly reduced in both groups immediately afterwards and post 30 minutes. The TRAINED group showed a significant reduction in fatigue 30 minutes after the end of the session. Effect size for all variables was considered small to moderate. The TRAINED group had significantly increased vigor immediately after the end of the session compared to baseline. However, the CONDITIONED group had significantly reduced vigor 30 minutes afterwards, in comparison to baseline. The increase in vigor in the TRAINED group was considered moderate (ES = 0.68), while the decrease in vigor in the CONDITIONED group was considered major (ES = −0.88). Conclusion: An ECT session is powerful enough to induce significant, albeit small and moderate, changes in mood states in both trained and untrained individuals in this particular type of exercise. Level of evidence II, Therapeutic studies-investigation of treatment results.


Metabolism ◽  
1984 ◽  
Vol 33 (8) ◽  
pp. 743-749 ◽  
Author(s):  
James O. Hill ◽  
Steven B. Heymsfield ◽  
Cliff McMannus ◽  
Mario DiGirolamo

2020 ◽  
Vol 9 (02) ◽  
pp. 153-165
Author(s):  
François Carré

AbstractThe benefits of regular physical activity whether in primary- or secondary prevention of cardiovascular disease are now irrefutable. Despite its well proven benefits, exercise training remains underused because of lack of insight and familiarity of the majority of cardiologists. This review offers cardiologists the necessary informations about the pathophysiological mechanisms, effects and limitations of the predominantly used training methods in various kardiovascular diseases.


Author(s):  
Tieh-Cheng Fu ◽  
Ming-Lu Lin ◽  
Chih-Chin Hsu ◽  
Shu-Chun Huang ◽  
Yu-Ting Lin ◽  
...  

AbstractExercise training influences the risk of vascular thrombosis in patients with peripheral arterial disease (PAD). Mitochondrial functionalities in platelets involve the cellular bioenergetics and thrombogenesis. This study aimed to elucidate the effect of cycling exercise training (CET) on platelet mitochondrial bioenergetics in PAD patients. Forty randomly selected patients with PAD engaged in general rehabilitation (GR) with CET (i.e., cycling exercise at ventilation threshold for 30 minute/day, 3 days/week) (GR + CET, n = 20) or to a control group that only received GR course (n = 20) for 12 weeks. Systemic aerobic capacity and platelet mitochondrial bioenergetics that included oxidative phosphorylation (OXPHOS) and electron transport system (ETS) were measured using automatic gas analysis and high-resolution respirometry, respectively. The experimental results demonstrated that GR + CET for 12 weeks significantly (1) elevated VO2peak and lowered VE-VCO2 slope, (2) raised resting ankle-brachial index and enhanced cardiac output response to exercise, (3) increased the distance in 6-minute walk test and raised the Short Form-36 physical/mental component scores, and (4) enhanced capacities of mitochondrial OXPHOS and ETS in platelets by activating FADH2 (complex II)-dependent pathway. Moreover, changes in VO2peak levels were positively associated with changes in platelet OXPHOS and ETS capacities. However, no significant changes in systemic aerobic capacity, platelet mitochondrial bioenergetics, and health-related quality of life (HRQoL) occurred following GR alone. Hence, we conclude that CET effectively increases the capacities of platelet mitochondrial bioenergetics by enhancing complex II activity in patients with PAD. Moreover, the exercise regimen also enhanced functional exercise capacity, consequently improving HRQoL in PAD patients.


Author(s):  
Lauren C. Chasland ◽  
Bu B Yeap ◽  
Andrew J. Maiorana ◽  
Yi X Chan ◽  
Barbara A Maslen ◽  
...  

As men age, serum testosterone (T) concentrations decrease, as do fitness, strength and lean mass. Whether testosterone treatment confers additive benefit to reverse these changes when combined with exercise training in middle-to-older aged men remains unclear. We assessed the effects of T treatment and exercise, alone and in combination, on aerobic capacity (VO2peak), body composition and muscular strength in men 50-70yrs, waist circumference ≥95cm and low-normal serum T (6-14nmol·L−1). Participants (n=80) were randomised to AndroForte5® (Testosterone 5.0%w/v, 100mg/2mL) cream (T), or matching placebo (P), applied transdermally daily, and supervised centre-based exercise (Ex) or no additional exercise (NEx), for 12-weeks. Exercise increased VO2peak and strength vs non-exercise (VO2peak: T+Ex:+2.5, P+Ex:+3.2mL·kg−1·min−1, P<0.001; leg press: T+Ex:+31, P+Ex:+24kg, P=0.006). T treatment did not affect VO2peak or strength. Exercise decreased total (T+Ex:-1.7, P+Ex-2.3kg, P<0.001) and visceral fat (T+Ex:-0.1, P+Ex:-0.3kg, P=0.003), and increased total (T+Ex:+1.4, P+Ex:+0.7kg, P=0.008) and arm lean mass (T+Ex:+0.5, P+Ex:+0.3kg, P=0.024). T treatment did not affect total or visceral fat, but increased total (T+Ex:+1.4, T+NEx:+0.7kg, P=0.015), leg (T+Ex:+0.3, T+NEx:+0.2kg, P=0.024) and arm lean mass (T+Ex:+0.5, T+NEx:+0.2kg, P=0.046). T+Ex increased arm lean mass (T+Ex:+0.5kg vs P+NEx:-0.0kg, P=0.001) and leg strength (T+Ex:+31 vs P+NEx:+12kg, P=0.032) compared to P+NEx, with no other additive effects. Exercise training was more effective than T treatment in increasing aerobic capacity and decreasing total and visceral fat mass. T treatment at therapeutic doses increased lean mass but conferred limited additional benefit when combined with exercise. Exercise should be evaluated as an anti-ageing intervention in preference to testosterone treatment in men.


2021 ◽  
Vol 15 (2) ◽  
pp. 128-132
Author(s):  
Rodrigo Guimarães Huyer ◽  
Mário Sérgio Paulillo Cillo ◽  
Carlos Daniel Cândido Castro Filho ◽  
Hallan Douglas Bertelli ◽  
Renato Morelli Berg

Objective: To assess postoperative clinical functional outcomes, based on the American Orthopaedic Foot & Ankle Society (AOFAS) score, of tendoscopies performed in the treatment of foot and ankle pathologies. Methods: Our comparative assessment used AOFAS scores obtained preoperatively and at early and late postoperative stages - 1 month and 6 to 12 months after surgery - of 14 patients with foot and ankle tendinopathies. These included peroneal tendon dislocation, peroneal tendonitis, and tearing of the peroneus longus or brevis, all treated with tendoscopy for peroneal reconstruction and tenorrhaphy. The AOFAS score was obtained by functional assessment during outpatient physical examination. We presented a descriptive analysis of cases, comparing scores over time through the Friedman test followed by Dunn’s test. The relationship between score variations and sex was assessed using the Mann-Whitney test; their comparison with age used Spearman’s linear correlation coefficient. Significance levels were 5%.Results: The AOFAS score showed important improvements such as preoperative scores of 56 and 67 followed by postoperative scores of 100 both in the early and late stages, supporting the efficacy and persistence of this treatment strategy. The p-value obtained after statistical analysis was <0.0001. Conclusion: We concluded that the treatment of foot and ankle comorbidities with tendoscopy, in addition to being less invasive, shows consistency and efficacy as demonstrated by the AOFAS score and functional assessment via postoperative physical examinations. AOFAS scores were increased and maintained at high levels in the postoperative period, demonstrating the efficacy of this procedure and the duration of treatment results. Level of Evidence IV; Case Series; Therapeutic Studies - Investigation of Treatment Results.


2021 ◽  
Vol 27 (3) ◽  
pp. 315-318
Author(s):  
Fanfan Li

ABSTRACT Introduction Human motor dysfunction can affect the quality of life, especially waist dysfunction. And an effective means to improve muscle strength during exercise. Object This article compares and analyzes the effectiveness of human muscle exercise on the decline in quality of life caused by motor dysfunction. Method The article divides patients with motor dysfunction into trunk isokinetic training group (experimental group) and waist and abdominal muscle functional training group (control group), and comparative analysis of related indicators before and after treatment. Results Before treatment, the specific indicators of the two were different (P>0.05). After treatment, the patients’ quality of life indicators and motor function indicators were significantly different (P<0.05). Conclusion Exercise has an obvious curative effect for patients with human motor dysfunction, and it is worthy of clinical promotion. Level of evidence II; Therapeutic studies - investigation of treatment results.


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