scholarly journals Schwannomatosis: report of a new case

1992 ◽  
Vol 50 (4) ◽  
pp. 539-542 ◽  
Author(s):  
Nélida S. Garretto ◽  
David Monteverde ◽  
Héctor Giócoli ◽  
Blanca I. Ravera ◽  
Hugo A. Molina ◽  
...  

Schwannomatosis is a rare disorder, still not quite well defined, seldom described in the literature. In this paper we report the case of male. Patient, 52 years old, who in the last 30 years developed five subcutaneous tumors within his limbs peripheral nerves, which histologically proved to be schwannomas. A brain computed tomography showed a partially calcified tumor in the left temporal lobe which most likely was a meningioma. A thorough clinical examination was unable to find signs of type I or type II neurofibromatosis. The present condition, probably a form of phacomatosis, has to be distinguished from neurofibromatosis and is considered as an independent clinical entity whose origin still awaits further detailed investigations.

2021 ◽  
Author(s):  
Ping Wang ◽  
Heng Ma ◽  
Qinglin Yang ◽  
Chengzhou Zhang

Abstract Objective The aim of the present study is to investigate the relationship between pulmonary hamartomas (PHs) and bronchi on multislice spiral computed tomography (MSCT) images. Methods The MSCT scans of 218 PHs from 216 pathologically confirmed patients were reviewed. The PHs were divided into two groups, namely, the central endobronchial and intraparenchymal groups, in accordance with location. Multiplanar reconstruction was used to demonstrate PH–bronchus relationship patterns. The PH–bronchus relationships in the intraparenchymal group were classified into five patterns: type I, the bronchus was cut off by the tumor; type II, the bronchus was contained within the tumor (air bronchogram sign); type III, the bronchus ran at the tumor periphery or was compressed by the tumor; and type IV, no tumor–bronchus relationship was observed. Results Nine (4.1%) PHs were assigned to the central endobronchial group and 209 (95.9%) PHs were assigned to the intraparenchymal group. In the endobronchial group, 1 (11.1%) PH was located in the trachea with the partial stenosis of the trachea, whereas the remaining 8 (88.9%) PHs were located in the lobar or segmental bronchus with the complete occlusion of the corresponding bronchus. In the intraparenchymal group, type IV (147, 70.3%) was most common pattern, followed by type III (54, 25.8%). Type I (8, 3.8%) was rare, and type II was not observed. Conclusion Central endobronchial PHs often obstructed bronchi, whereas only a few intraparenchymal PHs cut off bronchi. No air bronchogram sign was observed.


2018 ◽  
Vol 88 (6) ◽  
pp. 819-829 ◽  
Author(s):  
Wentian Sun ◽  
Kai Xia ◽  
Li Tang ◽  
Chenlu Liu ◽  
Ling Zou ◽  
...  

ABSTRACT Objective: To investigate the accuracy of panoramic radiography (PR) in diagnosing maxillary sinus-root relationships (SRRs). Materials and Methods: PubMed, EMBASE, CENTRAL, Web of Science, ScienceDirect, CBM, Baidu Scholar, and SIGLE were searched. The studies comparing the diagnostic accuracy of PR and computed tomography/cone-beam computed tomography (CT/CBCT) for SRR were included. Results: Eleven studies were included. Meta-analyses showed that, for type I SRR, PR had the highest specificity, positive likelihood ratio (+LR), diagnostic odds ratio (DOR), and area under the curve (AUC), with a high sensitivity and a low negative LR (−LR). For type IV, PR had a high DOR and AUC, with the highest sensitivity but a low +LR, the lowest –LR, and the lowest specificity. For type II, PR had the lowest AUC, with a low sensitivity, +LR, and DOR and a high −LR. For type III, PR had the lowest sensitivity, +LR, and DOR and the highest −LR. The distance from root tips to the maxillary sinus floor on PR was significantly longer (mean difference: −1.88 mm; 95% confidence interval: −2.19 to −1.57; P < .0001) than that on CT/CBCT. Conclusions: Currently available evidence suggests PR could be reliable for detecting type I SRR. PR has a good ability to confirm true type IV SRR but a poor ability to rule out false type IV SRR. For type II and III SRR, PR shows poor accuracy and tends to overestimate the extent of protrusion of the roots into the maxillary sinus. When PRs display type II, III, or IV SRR and related treatment is needed, CBCT should be used for further examinations.


2020 ◽  
Vol 48 (9) ◽  
pp. 030006052095099
Author(s):  
Chengyang Chen ◽  
Xing Wang ◽  
Jia Dong ◽  
Dianer Nie ◽  
Qianlan Chen ◽  
...  

Objective To evaluate temporal lung changes in coronavirus disease 2019 (COVID-19) in high-resolution computed tomography (HRCT) and to determine the appropriate computed tomographic (CT) follow-up time. Methods Eighty-six patients with two or more HRCT scans who were diagnosed with COVID-19 were included. The CT score and major CT findings were evaluated. Results Eighty-two (95.3%) patients had lesions on the initial HRCT scans. Most scans showed bilateral, multifocal lung lesions, with multiple lobes involved and diffuse distribution. For fifty-seven patients with type I (progress compared with the initial CT score), the CT score reached a peak at 12 days and the nadir at 36 days. For twenty-nine patients with type II (no progress compared with the initial CT score), the lowest CT score was reached at 23 days. On the final HRCT scans (>21 days), patients with a reticular pattern were older than those without a reticular pattern. Conclusion The appropriate follow-up time of CT scans is during the second week (approximately 12 days) and the fourth to fifth weeks (approximately 23–36 days) from the onset of illness. These times could help reduce the CT radiation dose and show timely changes in the course of the disease by CT.


2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Andre Luiz Ferreira Costa ◽  
Aline Kataki Paixão ◽  
Bianca Costa Gonçalves ◽  
Celso Massahiro Ogawa ◽  
Thiago Martinelli ◽  
...  

This study aimed to investigate the olfactory fossa according to the Keros classification using cone beam computed tomography. This cross-sectional study analysed cone beam computed tomography images selected from a database belonging to a radiology centre. The scans of 174 healthy patients were analysed by using the Xoran software. Gender, age, and side were correlated with the Keros classification. The mean age of the 174 patients was 45.3 years. The most prevalent Keros classification was type II (65.52%), followed by type III (20.69%) and type I (13.79%). No significant differences were found between Keros classification and the variables age, right side (pvalue = 0.4620), and left side (pvalue = 0.5709). There were also no significant differences between gender and the variables right side (pvalue = 0.1421) and left side (pvalue = 0.2136). Based on these results, we suggest that cone beam computed tomography can be recommended for analysis of the anterior skull base. Keros type II was the most prevalent type in our sample.


2019 ◽  
pp. 1-15 ◽  
Author(s):  
Eugene J. Koay ◽  
Matthew H.G. Katz ◽  
Huamin Wang ◽  
Xuemei Wang ◽  
Laura Prakash ◽  
...  

PURPOSE Effective preoperative regimens and biomarkers for pancreatic ductal adenocarcinoma (PDAC) are lacking. We prospectively evaluated fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX)-based treatment and imaging-based biomarkers for borderline resectable PDAC. METHODS Eligible patients had treatment-naïve, histology-confirmed PDAC and one or more high-risk features: mesenteric vessel involvement, CA 19-9 level of 500 mg/dL or greater, and indeterminate metastatic lesions. Patients received modified FOLFIRINOX and chemoradiation before anticipated pancreatectomy. Tumors were classified on baseline computed tomography as high delta (well-defined interface with parenchyma) or low delta (ill-defined interface). We designated computed tomography interface response after therapy as type I (remained or became well defined) or type II (became ill defined). The study had 80% power to differentiate a 60% from 40% resection rate (α = .10). Overall survival (OS) and progression-free survival (PFS) were estimated using the Kaplan-Meier method, and subgroups were compared using log-rank tests. RESULTS Thirty-three patients initiated therapy; 45% underwent pancreatectomy. The median OS was 24 months (95% CI, 16.2 to 29.6 months). For patients who did and did not undergo pancreatectomy, the median OS was 42 months (95% CI, 17.7 months to not estimable) and 14 months (95% CI, 9.0 to 24.8 months), respectively. Patients with high-delta tumors had lower 3-year PFS (4% v 40%) and 3-year OS rates (20% v 60%) than those with low-delta tumors (both P < .05). Patients with type II interface responses had lower 3-year PFS (0% v 29%) and 3-year OS rates (16% v 47%) than those with type I responses (both P < .001). CONCLUSION Preoperative FOLFIRINOX followed by chemoradiation for high-risk borderline resectable PDAC was associated with a resection rate of 45% and median OS of approximately 2 years. Our imaging-based biomarker validation indicates that personalized treatment may be achieved using these biomarkers at baseline and post-treatment.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Eman Al Mheiri ◽  
Jahanzeb Chaudhry ◽  
Salma Abdo ◽  
Rashid El Abed ◽  
Amar Hasan Khamis ◽  
...  

Abstract Background The aim of this study was to analyze the root and canal morphology of the maxillary permanent first molars in an Emirati population using cone-beam computed tomography (CBCT). Methods Two hundred and sixty-one CBCT scans were acquired. The data were extracted and anonymized to remove all patient identifiers. Two observers (an endodontic resident and an endodontist) evaluated all scans on diagnostic quality monitors. Results The prevalence of a second mesiobuccal canal (MB2) was 80.1% in all examined samples. Type II Vertucci classification, was the most common canal configuration (59%) in the mesiobuccal root, followed by Types I (19.9%) and IV (15.3%), while Type III was the least common (5.7%). Types I, II, and IV were significantly more common in the 21–40-year age group (P < 0.001), while Type III was observed significantly more often in the < 20-year age group (P < 0.001). No significant effect of gender on the prevalence of Vertucci classification in the mesiobuccal root of maxillary first molars (P = 0.74) was found. Analysis of bilateral symmetry showed that 80% teeth had perfect bilateral symmetry, whereas 20% were asymmetrical. Type II canal configuration showed the highest prevalence of bilateral symmetry (48.7%), followed by Type I (15%) and Type IV (10%), while Type III showed the least prevalence of symmetry (3%). Conclusions This was the first study to analyze the prevalence of MB2 canal in an Emirati population. Our results indicate high prevalence of MB2 (80.1%) and emphasize the importance of using advanced techniques to locate the MB2 canal.


2022 ◽  
Vol 30 (3) ◽  
pp. 95-99
Author(s):  
Karina Sarango-Amay ◽  
Alberth Muñoz-Gualan

Schizencephaly is a rare congenital brain malformation characterized by clefts in the cerebral cortex, it is classified in Type I (open lip) and Type II (close-lip). Patients with schizencephaly present seizures, hydrocephalus, motor and mental deficits. Ultrasound is used for in-utero and newborns patients’ diagnosis, and MRI or CT for already born patients. The management of schizencephaly is conservative, with rehabilitation in motor or mental deficits, medication or surgery for seizures and shunt in hydrocephalus with increased intracranial pressure. In the literature, only few giant bilateral cases have been reported. We report a case of giant bilateral open lip schizencephaly, in a 10-day old male patient, presenting with mild hypotonia and no seizures. This case is rare because the relatively benign features compared to other reported cases.


Author(s):  
Jaynit Tandon ◽  
Sonali Taneja ◽  
Vidhi Kiran Bhalla ◽  
Akshay Rathore

Introduction: Adequate knowledge of the anatomic variation and root canal morphology is paramount for long term endodontic success. The presence of two canals in Mesiobuccal (MB) root is commonly associated with maxillary molars in various populations. Aim: To retrospectively evaluate the prevalence of a second mesiobuccal canal (MB2) in maxillary first and second molars in Delhi-National Capital Region (NCR) population using Cone Beam Computed Tomography (CBCT) analysis. Materials and Methods: This retrospective study evaluated the records of complete maxillary CBCT scans of 204 maxillary first and second molars from January 2016 till May 2019 from different CBCT centres in Delhi-NCR region to determine the anatomy and morphology in June 2019. The prevalence of second MB2 canals was recorded and associated with age, gender and symmetry. The z-test for proportions was used to assess the differences among the subgroups. Results: The number of roots in 204 teeth in both maxillary molars were determined. The prevalence of 3-rooted configuration was 98.55% in maxillary first molars and 79.4% in maxillary 2nd molars. Also, in maxillary 2nd molars, 7.4% were single rooted and 13.2% had 2-rooted configuration. Three rooted configuration and variable canal number was commonly reported in maxillary molars. Prevalence of MB2 canal was 87.2% in maxillary 1st molars and 64.2% in maxillary 2nd molars. Also, the prevalence was 87.2% bilaterally in maxillary first molars and 65.7% on the right and 53.9% on the left in maxillary second molars respectively. Type IV canal configuration was most prevalent in 44.60% of maxillary first molars and type 1 configuration (35.78%) for the maxillary second molars. Conclusion: Prevalence of MB2 canals in maxillary first and second molars was found to be high in North Indian population and the clinician should suspect its presence in all cases. Prevalence of MB2 had bilaterally symmetrical distribution without any association with age or gender. The MB roots were more likely to exhibit type IV and type II canal configurations in maxillary first molars and type I and type II configurations in second molars.


2020 ◽  
Vol 10 (9) ◽  
pp. 2223-2227
Author(s):  
Rui Mei ◽  
Fang Fan ◽  
Lu Lv ◽  
Fang Wang ◽  
Xiaobo Liu ◽  
...  

The purpose of this study is to investigate the effects of family therapy on brain computed tomography (CT) information in unipolar depression patients. In this study, 35 cases of unipolar depression patients who visited xxx hospital from March 2017 to August 2019 but received no systematic treatment were taken as the study subjects. CT scan was used to detect and compare the CT values of left frontal lobe, right frontal lobe, left temporal lobe and right temporal lobe of patients with depression before and three months after family treatment. Patients’ levels of depression and anxiety before and after treatment were determined by Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA). The cognitive function of patients before and after treatment was evaluated by Mini Mental State Examination (MMSE). The physical and social function, and mental health of them were assessed by health status questionnaire (SF-36). The correlation between CT values of each lobe and clinical characteristics of patients was analyzed by multivariate linear regression model. The results showed that the CT values and SF-36 scores of the left and right frontal lobe after treatment were significantly higher than that before treatment (P < 0.05), while the HAMD MMSE scores were significantly lower than those before treatment (P < 0.05). The linear-regression analysis results showed that CT values of the left frontal lobe were negatively correlated with the patient’s age and disease course (P < 0.05), and CT values of the right frontal lobe were negatively correlated with the patient’s age (P < 0.05), and CT values of the left temporal lobe were negatively correlated with the patient’s disease course (P < 0.05). It indicates that the pathogenesis of depression is related to the function of brain structure. However, the social ability of unipolar depression patients and their emotional depression and psychological state can be effectively improved by family therapy, which also has a significant effect on the recovery of the disease.


2014 ◽  
Vol 2014 ◽  
pp. 1-7
Author(s):  
Raed Hakam Mukhaimer

Aim. The purpose of this study was to investigate the number of canals and variations in root canal configuration in the mandibular permanent first molar teeth of a Palestinian population using cone-beam computed tomography (CBCT). Methods. A sample of 320 extracted double-rooted mandibular permanent first molars from Palestinian population was collected for this study and scanned with CBCT scanner. The following observations were made: number of root canals per root and canal configuration in each root based on Vertucci’s classification. Results. Of the 320 mandibular first molars analyzed, 174 (54.4%) had three canals, 132 teeth (41.3%) had four canals, and only four teeth had two canals. The most common canal configuration in the mesial roots was Vertucci type IV (53.8%) followed by type II (38.8%). In the distal roots, the most prevalent canal configuration was Vertucci type I (57.5%) followed by type II ( 22.5%) and type III (10.6%). Conclusion. Our results showed that the number of canals and canal configuration in Palestinian population were consistent with previously reported data. The present study also indicates that CBCT is helpful as a diagnostic tool for the investigation of root canal morphology.


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