scholarly journals Influence of arterial hypertension treated with losartan on skin healing in rats

2006 ◽  
Vol 21 (3) ◽  
pp. 144-150 ◽  
Author(s):  
Maria de Lourdes Pessole Biondo-Simões ◽  
Ana Denise Zazula ◽  
Ariana Braga Gomes ◽  
Caroline Poncio ◽  
Luiz Fernando Bleggi Torres ◽  
...  
Keyword(s):  
Type I Collagen ◽  
Isotonic Saline ◽  
Skin Incision ◽  
Lower Percentage ◽  
Left Renal Artery ◽  
Type I ◽  
Group Iii ◽  
Group I ◽  
Group Ii ◽  
Skin Healing

PURPOSE: To evaluate the role of Losartan in skin healing repair. METHODS: One hundred and eleven male Wistar rats were distributed into four groups, at random. Group I (n=31) underwent a laparotomy to induce hypertension by stenosis of the left renal artery, and 48 hours later it received Losartan (10 mg/Kg) daily. Group II (n=30) went through the same procedure and received isotonic saline solution. Group III (n=30) underwent a simulated laparotomy. Group IV (n=20) to confirm the induced hypertension method. Ketamine and Xylazin anesthesia was used in every painful/stressful procedure. After 15 days, skin healing repair was studied by a dorsal midline skin incision and second layer-skin incision in groups I, II and III, that was sutured in one layer with 4-0 nylon suture. Samples of the dorsal wall scar were taken 4, 7 and 14 days after the last procedure, and sent to strength and displacement analysis and histological preparation. RESULTS: By the 4th and 7th days of the analysis, group II scars showed to be less resistant than group III scars (p<0,05). The total amount of collagen was higher in group III on the three studied periods. The percentage occupied by total collagen in the wound area, on the 14th day, was lower in group I, due to its lower percentage of type I collagen CONCLUSION: Scars treated with Losartan were initially less resistant and had a lower collagen deposition.

Effect of Enamel Deproteinization in Primary Teeth

2018 ◽  
Vol 42 (1) ◽  
pp. 45-49 ◽  
Author(s):  
Ananthi Christopher ◽  
R Krishnakumar ◽  
N Venugopal Reddy ◽  
G Rohini
Keyword(s):  
Surface Area ◽  
Group Iv ◽  
Enamel Surface ◽  
Tooth Surface ◽  
Type I ◽  
Group Iii ◽  
Group I ◽  
Electron Microscope Analysis ◽  
Group Ii ◽  
Quality Type

Objective: To evaluate and compare the topographical features of enamel surface, etched with different materials. Study Design: 10 extracted human primary molars were randomly selected and cut and trimmed to 1 mm2. Each group comprised of 10 blocks and the enamel was treated as follows: Group I–35% H3PO4; Group II–5.25% NaOCl + 35% H3PO4 ;Group III–5.25% NaOCl; Group IV no treatment was carried out. All the samples were prepared for Scanning electron microscope analysis. The images were obtained and evaluated for the quality type I–II etching of the enamel surface using Auto-CAD 2011 software. Statistical Analysis Used: Wilcoxon Signed Ranks Test (p&lt;0.001). Results: The mean surface area of type I and II etching pattern values for Group- I was 39608.18 μm2 and Group- II was 45051.34 μm2. Conclusion: Deproteinization with 5.25% Sodium hypochlorite prior to acid etching could be used to increase the surface area of adhesion of composite material with the tooth surface.

Effect of parathyroid hormone on renal excretion of sodium and hydrogen ions

1977 ◽  
Vol 55 (3) ◽  
pp. 628-638 ◽  
Author(s):  
Hubert Hermkens ◽  
Tewfik Nawar ◽  
Claude Caron ◽  
Gerard E. Plante
Keyword(s):  
Parathyroid Hormone ◽  
Renal Plasma Flow ◽  
Extracellular Volume ◽  
Phosphate Transport ◽  
Left Renal Artery ◽  
Group Iii ◽  
Titratable Acid ◽  
Group I ◽  
Group Ii ◽  
The Right

The contribution of parathyroid hormone (PTH) to the renal adjustment of phosphate transport has been extensively investigated, whereas the action of this hormone on bicarbonate and hydrogen excretion has not received as much attention.Nineteen dogs were studied before and during a 2-h infusion of PTH in the left renal artery (8 mU/min per kilogram) under slight expansion of extracellular volume (fractional sodium excretion = U/FNa = 3.8 ± 0.3%). Group I (n = 7) was studied under normal acid–base condition while group II (n = 6) was studied during metabolic acidosis. Bicarbonate titration curves were obtained from group III (n = 6) in which the right kidney was used as control. In all studies, plasma pCO2 was kept constant.[Formula: see text] rose from 4.2 ± 1.1 to 15.6 ± 3.0% and from 3.8 ± 0.4 to 25.0 ± 3.5% in groups I and II, respectively. U/FNa was unchanged in both groups. [Formula: see text] rose from 5.8 ± 0.6 to 10.1 ± 0.7% in group I but remained at 1.0 ± 0.2% in group II during PTH. Urinary titratable acid and ammonium were not influenced by PTH in group II. In group III, plasma HCO3 was progressively increased from 15 to 40 mM/litre. For all plasma values exceeding 22 mM/litre, HCO3 reabsorption was 1 mM/litre of filtrate lower in the left than in the right kidney. Glomerular filtration and renal plasma flow remained constant during PTH.The results indicate that PTH affects sodium and hydrogen excretion in a very modest fashion. Bicarbonaturia obtains whenever plasma HCO3 exceeds 22 mM/litre during PTH. This phenomenon is associated with a demonstrable reduction in tubular HCO3 reabsorption per unit of filtrate.

scholarly journals Study on Role of Oral Clonidine in Laparoscopic Cholecystectomy Surgery – A Comparative Study

2009 ◽  
Vol 21 (1) ◽  
pp. 12-20 ◽  
Author(s):  
Amirul Islam ◽  
Mozaffer Hossain ◽  
AKM Akhtaruzzaman ◽  
UH Shahera Khatun
Keyword(s):  
Heart Rate ◽  
Laparoscopic Cholecystectomy ◽  
Skin Incision ◽  
Mean Difference ◽  
Group Iii ◽  
Oral Clonidine ◽  
Group I ◽  
The Mean ◽  
Group Ii

Laparoscopic surgical techniques have been rapidly accepted by the surgeon worldwide e.g. especially laparoscopic cholecystectomy, with published reports describing the benefits of less postoperative pain, reduced hospital stay and an earlier return to work. The hall mark of laparoscopic surgery is the creation of pneumoperitoneum with pressurized CO2. The high solubility of CO2 increases systemic absorption by the vasculature of the peritoneum. This, combined with smaller tidal volumes because of poor lung complication, leads to increased arterial CO2 levels which is known as hypercarbia. If hypercarbia allowed to develop, will stimulate the sympathetic nervous system and thus increase heart rate, blood pressure, and the risk of dysrhythmias. These effects can prove especially challenging in patients with restrictive lung disease, impaired cardiac function, or intravascular volume depletion . The present study was to evaluate the role of oral clonidine and atenolol in controlling tachycardia and hypertension associated with pneumoperitoneum with CO2 during laparoscopic cholecystectomy under general anaesthesia and also to find out the best premedicant in controlling heamodynamic instability in laparo-scopic cholecystomy. 75 patients schedule for laparoscopic cholecystectomy were randomly selected by blind envelop method. Patients were divided equally into three groups, which were Group-I: Oral clonidine(150ìgm), Group-II: oral atenolol(25mg) and Group-III: placebo (vitamin-c tablet), twenty five patients were in each group The mean difference of pulse rate at different times was significant (p<0.05), however just before induction, just after skin incision and just after insufflations CO2 were not significant (p>0.05). The mean differences of systolic, diastolic BP at different times were not significant (p>0.05), however BP was almost stable just before induction to the end of the operation in group I patients. The mean difference of SPO2 at different times was not significant(p>0.05) but just after intubations (99.6%±0.5% in group I, 99.3% ±0.5% in group II and 98.7%±1.1% in group III) and just after skin incision (99.5%±0.6% in group I, 98.9%± 0.6% in group II and 98.3% ±0.9 % in group III) was significant (p<0.05). The mean difference of ETCO2 at different times was not significant (p>0.05) however after 5 minutes insufflations (35.8±0.8 mmHg in group I, 36.5±0.5 mmHg in group II and 35.5±0.8 mmHg in group III) was significant (p<0.05). The mean (±SD) halothane intake of group I patients was 0.49±0.06%, 0.56±0.10% in group II and 0.66±0.09% in group III. The mean (±SD) duration of first analegesic demand of the patents was 90.8±8.5 minutes in group I, 74.0±8.5 minutes in group II and 72.2±8.7 minutes in group III. The mean difference of halothane requirement & duration of first analegesic demand were significant (p<0.05). The aldrete recovery status of original criteria were almost similar in three groups (p>0.05). We can conclude that oral clonidine and atenolol to control heart rate & haemodynamic instability in laparoscopic cholecystectomy under general anaesthesia is better than placebo.   Journal of BSA, Vol. 21, No. 1, January 2008 12-20

Ultrastructural Lesions Produced by Alcohol and Sucrose in the Heart and Liver of C57BL Mice

1970 ◽  
Vol 28 ◽  
pp. 208-209
Author(s):  
K.K. SEKHRI ◽  
C.S. ALEXANDER ◽  
H.T. NAGASAWA
Keyword(s):  
Osmium Tetroxide ◽  
Male Mice ◽  
Alcohol Group ◽  
Group Iii ◽  
Group I ◽  
C57bl Mice ◽  
Group Ii

C57BL male mice (Jackson Lab., Bar Harbor, Maine) weighing about 18 gms were randomly divided into three groups: group I was fed sweetened liquid alcohol diet (modified Schenkl) in which 36% of the calories were derived from alcohol; group II was maintained on a similar diet but alcohol was isocalorically substituted by sucrose; group III was fed regular mouse chow ad lib for five months. Liver and heart tissues were fixed in 2.5% cacodylate buffered glutaraldehyde, post-fixed in 2% osmium tetroxide and embedded in Epon-araldite.

Heterogeneity and Immunochemical Properties of Anti-β2-glycoprotein I Autoantibodies

1998 ◽  
Vol 80 (09) ◽  
pp. 393-398 ◽  
Author(s):  
V. Regnault ◽  
E. Hachulla ◽  
L. Darnige ◽  
B. Roussel ◽  
J. C. Bensa ◽  
...  
Keyword(s):  
Fluid Phase ◽  
Anticardiolipin Antibodies ◽  
Dual Reactivity ◽  
Group Iii ◽  
Important Group ◽  
Epitope Specificity ◽  
Glycoprotein I ◽  
Group I ◽  
Group Ii ◽  
Sufficient Concentration

SummaryMost anticardiolipin antibodies (ACA) associated with antiphospholipid syndrome (APS) are directed against epitopes expressed on β2-glycoprotein I (β2GPI). Despite a good correlation between standard ACA assays and those using purified human β2GPI as the sole antigen, some sera from APS patients only react in the latter. This is indicative of heterogeneity in anti-β2GPI antibodies. To characterize their reactivity profiles, human and bovine β2GPI were immobilized on γ-irradiated plates (β2GPI-ELISA), plain polystyrene precoated with increasing cardiolipin concentrations (CL/β2GPI-ELISA), and affinity columns. Fluid-phase inhibition experiments were also carried out with both proteins. Of 56 selected sera, restricted recognition of bovine or human β2GPI occurred respectively in 10/29 IgA-positive and 9/22 IgM-positive samples, and most of the latter (8/9) were missed by the standard ACA assay, as expected from a previous study. Based on species specificity and ACA results, IgG-positive samples (53/56) were categorized into three groups: antibodies reactive to bovine β2GPI only (group I) or to bovine and human β2GPI, group II being ACA-negative, and group III being ACA-positive. The most important group, group III (n = 33) was characterized by (i) binding when β2GPI was immobilized on γ-irradiated polystyrene or cardiolipin at sufficient concentration (regardless of β2GPI density, as assessed using 125I-β2GPI); (ii) and low avidity binding to fluid-phase β2GPI (Kd in the range 10–5 M). In contrast, all six group II samples showed (i) ability to bind human and bovine β2GPI immobilized on non-irradiated plates; (ii) concentration-dependent blockade of binding by cardiolipin, suggesting epitope location in the vicinity of the phospholipid binding site on native β2GPI; (iii) and relative avidities approximately 100-fold higher than in group III. Group I patients were heterogeneous with respect to CL/β2GPI-ELISA and ACA results (6/14 scored negative), possibly reflecting antibody differences in terms of avidity and epitope specificity. Affinity fractionation of 23 sera showed the existence, in individual patients, of various combinations of antibody subsets solely reactive to human or bovine β2GPI, together with cross-species reactive subsets present in all samples with dual reactivity namely groups III and II, although the latter antibodies were poorly purified on either column. Therefore, the mode of presentation of β2GPI greatly influences its recognition by anti-β2GPI antibodies with marked inter-individual heterogeneity, in relation to ACA quantitation and, possibly, disease presentation and pathogenesis.

Oxygen Fraction Adjustment According to Body Surface Area during Extracorporeal Circulation

2015 ◽  
Vol 18 (3) ◽  
pp. 098
Author(s):  
Cem Arıtürk ◽  
Serpil Ustalar Özgen ◽  
Behiç Danışan ◽  
Hasan Karabulut ◽  
Fevzi Toraman
Keyword(s):  
Body Temperature ◽  
Surface Area ◽  
Body Surface Area ◽  
Body Surface ◽  
Extracorporeal Circulation ◽  
Group Iii ◽  
Oxygen Fraction ◽  
Arterial Blood ◽  
Group I ◽  
Group Ii

<p class="p1"><span class="s1"><strong>Background:</strong> The inspiratory oxygen fraction (FiO<sub>2</sub>) is usually set between 60% and 100% during conventional extracorporeal circulation (ECC). However, this strategy causes partial oxygen pressure (PaO<sub>2</sub>) to reach hyperoxemic levels (&gt;180 mmHg). During anesthetic management of cardiothoracic surgery it is important to keep PaO<sub>2</sub> levels between 80-180 mmHg. The aim of this study was to assess whether adjusting FiO<sub>2</sub> levels in accordance with body temperature and body surface area (BSA) during ECC is an effective method for maintaining normoxemic PaO<sub>2</sub> during cardiac surgery.</span></p><p class="p1"><span class="s1"><strong>Methods:</strong> After approval from the Ethics Committee of the University of Acıbadem, informed consent was given from 60 patients. FiO<sub>2</sub> adjustment strategies applied to the patients in the groups were as follows: FiO<sub>2</sub> levels were set as 0.21 × BSA during hypothermia and 0.21 × BSA + 10 during rewarming in Group I; 0.18 × BSA during hypothermia and 0.18 × BSA + 15 during rewarming in Group II; and 0.18 × BSA during hypothermia and variable with body temperature during rewarming in Group III. Arterial blood gas values and hemodynamic parameters were recorded before ECC (T1); at the 10th minute of cross clamp (T2); when the esophageal temperature (OT) reached 34°C (T3); when OT reached 36°C (T4); and just before the cessation of ECC (T5).</span></p><p class="p1"><span class="s1"><strong>Results:</strong> Mean PaO<sub>2</sub> was significantly higher in Group I than in Group II at T2 and T3 (<em>P</em> = .0001 and <em>P</em> = .0001, respectively); in Group I than in Group III at T1 (<em>P</em> = .02); and in Group II than in Group III at T2, T3, and T4 <br /> (<em>P</em> = .0001 for all). </span></p><p class="p1"><span class="s1"><strong>Conclusion: </strong>Adjustment of FiO<sub>2</sub> according to BSA rather than keeping it at a constant level is more appropriate for keeping PaO<sub>2</sub> between safe level limits. However, since oxygen consumption of cells vary with body temperature, it would be appropriate to set FiO<sub>2</sub> levels in concordance with the body temperature in the <br /> rewarming period.</span></p>

Features of the cervix uteri in women of reproductive age with endometrial polyps and micropolyps

2016 ◽  
pp. 108-111
Author(s):  
T.F. Tatarchuk ◽  
◽  
D.G. German ◽  
Keyword(s):  
Reproductive Age ◽  
Cervix Uteri ◽  
Control Group ◽  
Women Of Reproductive Age ◽  
Endometrial Polyps ◽  
Group Iii ◽  
Aggressive Form ◽  
Group I ◽  
Group Ii ◽  
Control Group Group

The article presents the comparative analysis of the state of the cervix in women with endometrial polyps and micropolyps. Patients and methods. The study involved 130 patients aged 18-35 years: 70 patients with endometrial polyps (group I), 30 patients with micropolyps (group II) and 30 patients of the control group (group III). Results. According to the anamnesis of women in the I group were significantly more frequent diseases of the cervix, which corrected physical surgery methods, in particular cryodestruction. In group II, the representatives of these indicators were similar to healthy. Normal colposcopic picture met significantly less frequently in patients and I, and II group. The differences in the incidence of HPV high oncogenic risk in all groups were not statistically significant. Conclusion. Destructive methods used in the detection of any changes in the cervix are often overly aggressive, form scars and contributing to inflamaciones process. In the chain of events leading to the formation of PE, cervical pathology and its correction can take the basic place. Key words: endometrial polyp, micropolyps, chronic endometritis, uterine cervix, colposcopy.

THE USE OF BOLUSES REDUCES THE NEGATIVE EFFECT OF SUBCLINICAL KETOSIS ON THE REPRODUCTIVE FUNCTION OF HIGHLY PRODUCTIVE COWS

2020 ◽  
Author(s):  
Г.В. ШИРЯЕВ ◽  
Ю.Г. ТУРЛОВА ◽  
Г.С. НИКИТИН
Keyword(s):  
Reproductive Function ◽  
Sexual Cycle ◽  
Feed Additive ◽  
Hydroxybutyric Acid ◽  
Subclinical Ketosis ◽  
Group Iii ◽  
Group I ◽  
Negative Effect ◽  
Group Ii ◽  
Reproductive Indices

Изучено влияние кормовой добавки в форме индивидуальных болюсов Метраболь на возможность снижения негативного влияния субклинического кетоза (СКК) и результативность искусственного осеменения высокопродуктивных молочных коров в посттранзитный период. Животные были подобраны по принципу условных аналогов и разделены на 3 группы в зависимости от концентрации β-оксимасляной кислоты в их крови. В I группе (n=18) у коров не было СКК, концентрация кислоты составляла <1,0 ммоль/л, во II группе (n=21) у животных зарегистрирован СКК, концентрация кислоты — 1,0…1,4 ммоль/л. С целью поиска решения по снижению негативного влияния СКК на репродуктивные показатели была сформирована III группа коров, переболевших СКК (n=24) с концентрацией β-оксимасляной кислоты в крови 1,0…1,4 ммоль/л, но с использованием болюсов, применяемых для ускоренного восстановления репродуктивной функции коров после отела. Важной составляющей опыта явилось то, что к моменту гормональной синхронизации у коров всех 3 групп фиксировалось отсутствие СКК (снижение β-оксимасляной кислоты до уровня <1,0 ммоль/л). Для синхронизации полового цикла выбрана схема Пресинх-овсинх. Установлено, что гормональная синхронизация животных, перенесших СКК, в сравнении со здоровыми, не позволяет снизить негативное влияние данного нарушения обмена веществ. Во II группе у животных зафиксированы самые низкие репродуктивные показатели (количество использованных доз; индекс осеменения, сервис-период; время от первого до успешного осеменения; результат первичного осеменения; количество животных, осемененных 3 и более раз). В III группе применение болюсов позволило, в сравнении с животными II группы, не только избежать отрицательного воздействия СКК, но и превзойти по изучаемым параметрам животных из I группы. The effect of the feed additive in the form of individual boluses Metrabol on the possibility of reducing the negative effect of subclinical ketosis (CCK) and the effectiveness of artificial insemination of highly productive dairy cows in the post-transit period was studied. The animals were selected according to the principle of conditional analogs and divided into 3 groups depending on the concentration of β-hydroxybutyric acid in their blood. In group I (n=18), the cows did not have SSC, the acid concentration was <1.0 mmol/L, in group II (n=21), SSC was registered in animals — 1.0...1.4 mmol / L. In order to find a solution to reduce the negative effect of CCB on reproductive indices, a group III of cows was formed who had CCB (n = 24) with a concentration of β-hydroxybutyric acid in their blood of 1.0...1.4 mmol/L, but using boluses, used to accelerate the restoration of the reproductive function of cows after calving. An important component of the experiment was that by the time of hormonal synchronization, cows of all 3 groups had no SSC (decrease in β-hydroxybutyric acid to a level of <1.0 mmol/L). To synchronize the sexual cycle, the Pressinh-ovsinh scheme was chosen. It was found that hormonal synchronization of animals that underwent SSC, in comparison with healthy ones, does not allow reducing the negative effect of this metabolic disorder. In group II, animals had the lowest reproductive indices (number of doses used; insemination index, service period; time from first to successful insemination; result of primary insemination; number of animals inseminated 3 or more times). In group III, the use of boluses made it possible, in comparison with animals of group II, not only to avoid the negative effect of SSC, but also to surpass the animals from group I in terms of the studied parameters.

Serum Endocrine Profile in Relation to Estrus Synchronization in Surti Does

2018 ◽  
Vol 13 (03) ◽  
Author(s):  
M. M. Chaudhary ◽  
C. T. Khasatiya ◽  
S. B. Patel ◽  
S. S. Chaudhary ◽  
V. B. Atara ◽  
...  
Keyword(s):  
Jugular Vein ◽  
Estrus Synchronization ◽  
Progesterone Concentration ◽  
Serum Progesterone ◽  
Blood Samples ◽  
Group Iii ◽  
Group I ◽  
Endocrine Profile ◽  
Group Ii ◽  
And Control

The serum progesterone and estradiol profiles during synchronization of estrus by buck effect and PGF2α treatments were monitored in Surti does. Total eighteen non-pregnant does selected were evenly divided into 3 groups, 6 does in each group. The does of Group I were teased with a sexuallyactive- apronized buck; and those of Group II were treated with PGF2α, i.e., Inj. Lutalyse® @ 7.5 mg/doe IM twice 11 days apart, while the Group III served as untreated control. Blood samples were collected from all the animals on day 0 (before 1st PGF2α injection), 3rd day (during treatment), 11th day (before 2nd PGF2α injection), 14th day (after treatment) and 40th day (post-service) by jugular vein puncture. The serum separated was stored at -20°C till further analysis. In all the three groups, 83.33% does, conceived at first service in the sampling cycle. The overall mean serum progesterone concentration of Group I does (5.82±0.72 ng/ml) was significantly higher (p less than 0.01) as compared to Group II (2.93±0.38 ng/ml) and III (2.88±0.30 ng/ml). Similarly, the overall mean serum progesterone concentration of Surti does on day 0 (2.65±0.46 ng/ml), 3rd (2.56±0.80 ng/ml), 11th (4.45±0.84 ng/ml) and 14th (3.40±0.63 ng/ml) did not differ significantly, but the overall mean level at day 40 (6.31±0.45 ng/ml) was significantly (p less than 0.01) higher, because most of animals became pregnant at that time. The overall mean serum oestradiol-17β levels of Group I (24.40±2.98 pg/ ml) was significantly higher (p less than 0.01) than in Group II (15.77±1.77 pg/ml) and III (12.21±1.45 pg/ ml). On the other hand, the overall mean serum oestradiol-17β levels of Surti does on day 0 (12.89±1.21 pg/ml), 3rd (15.84±1.74 pg/ml), 11th (14.81±1.96 pg/ml), 14th (22.15±2.97 pg/ml) and 40th (21.64±5.16 pg/ml) did not differ significantly (p>0.05) and the slightly higher overall mean level found at 40th day might be the influence of the non-pregnant does at first service in the cumulative animals. The hormonal profile reflected the initiation of cyclicity and establishment of pregnancy in treated and control animals.

Bridging the gap between perioperative pelvic floor training and urologic surgeries with risk of incontinence by digital technologies: a survey. (Preprint)

2020 ◽  
Author(s):  
Jan Niclas Mumm ◽  
Lucas Bohn ◽  
Lennert Eismann ◽  
Alexander Buchner ◽  
Theresa Vilsmaier ◽  
...  
Keyword(s):  
At Risk ◽  
Pelvic Floor ◽  
Digital Technologies ◽  
Preventive Treatment ◽  
Final Analysis ◽  
Chi Square ◽  
Group Iii ◽  
Pelvic Floor Training ◽  
Group I ◽  
Group Ii

BACKGROUND Pelvic floor training (PFT) is the gold standard for conservative treatment of male stress urinary incontinence. OBJECTIVE To evaluate patients´ perspective at risk of incontinence on PFT and application of digital technologies for PFT. METHODS Patients undergoing transurethral surgery of the prostate (group I), radical prostatectomy (group II) or treatment at a specialized incontinence outpatient clinic (group III) were surveyed anonymously. Chi-Square test and Kruskal-Wallis-analysis were used for statistical analysis. RESULTS 180 patients were included in the final analysis. In group I (n=35) no patient underwent PFT prior to transurethral surgery. 23.5% of patients in group II (n=51) and 95.7% of patients in group III (n=94) performed PFT. 11.4% in group I, 80.4% in group II and 91.5% in group III have been advised to perform PFT by their urologist. Regarding the information level on PFT, patients from group I (median 1, range 0-5) are less satisfied than patients from group II (median 3, 0-9) or group III (median 5, range 0-10, p<0.001). 88.6% of patients from group I are willing to perform PFT as preventive treatment or to avoid incontinence surgery, 100% from group II and 68.4% from group III (p<0.001). The likelihood to use digital PFT is higher in group I (median: 9, range 0-10) and II (median: 9, range 0-10) than in group III (median: 4, range 0-10, p<0.001). CONCLUSIONS Patients at risk of incontinence currently have limited access to PFT, although they are willing to perform PFT. Digital PFT is highly accepted by patients preoperatively and might be a valuable tool to increase PFT participation.

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