scholarly journals Neutropenia, agranulocytosis and dipyrone

2005 ◽  
Vol 123 (5) ◽  
pp. 247-249 ◽  
Author(s):  
Nelson Hamerschlak ◽  
Alexandre Biasi Cavalcanti
Keyword(s):  
Latin America ◽  
Side Effects ◽  
Mortality Rate ◽  
Case Control Study ◽  
Case Control ◽  
Serious Disease ◽  
Control Study

CONTEXT: Neutropenia and agranulocytosis may be defined as granulocyte counts of less than 1,500/mm³ and 500/mm³, respectively. Agranulocytosis is a rare and serious disease often caused by drugs. Its mortality rate is around 10%. The most common manifestations are infections such as tonsillitis, pharyngitis, stomatitis or pneumonia. Although dipyrone is one of the drugs known to be associated with agranulocytosis, the strength of the association has been a matter of much debate. Moreover, alternative analgesic and antipyretic agents are not devoid of serious side effects. CONCLUSIONS: It is therefore necessary to establish the incidence of agranulocytosis in Latin America and the role of dipyrone. The ongoing LATIN Study is a multicenter international case-control study that will provide answers for these questions.

scholarly journals P2-233: The role of hippocampal atrophy for the differentiation between MCI subtypes: Results of a case-control study

2012 ◽  
Vol 8 (4S_Part_9) ◽  
pp. P341-P341
Author(s):  
Martha Dlugaj ◽  
Christoph Mönninghoff ◽  
Hans-Jürgen Huppertz ◽  
Isabel Wanke ◽  
Daniel Jokisch ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Hippocampal Atrophy ◽  
Control Study

Risk factors for perinatal mortality: a case control study from Thiruvananthapuram, Kerala, India

2017 ◽  
Vol 6 (6) ◽  
pp. 2452 ◽  
Author(s):  
Mayadevi Brahmanandan ◽  
Lekshmi Murukesan ◽  
Bindu Nambisan ◽  
Shaila Salmabeevi
Keyword(s):  
Risk Factors ◽  
Mortality Rate ◽  
Perinatal Mortality ◽  
Case Control Study ◽  
Gestational Hypertension ◽  
Significant Risk ◽  
Case Control ◽  
Maternal Risk ◽  
Perinatal Mortality Rate ◽  
Control Study

Background: The greatest risks to life are in its very beginning. Although a good start in life begins well before birth, it is just before, during, and in the very first hours and days after birth that life is most at risk. This prospective case control study was designed on maternal risk factors for perinatal mortality.Methods: This was a case control study conducted in the Department of Obstetrics and Gynecology and Department of Paediatrics, Medical College Trivandrum for one year period in 2004-2005. The cases were all the fresh and macerated still births and early neonatal death cases during the study period. The controls were chosen as the next delivery entry in the OR register.Results: During this period, the total number of deliveries was 14,796 and there were 431 perinatal deaths. The perinatal mortality rate was 29.12. This was much higher compared to Kerala’s perinatal mortality rate of 10, the reason being that the study is conducted in a tertiary referral hospital with one of the best new born care nurseries and a large number of referrals. The most significant risk factors for perinatal mortality were low socio-economic status, referrals, late registration, prematurity, low birth weight, intra-uterine growth restriction, maternal diseases like gestational hypertension and gestational diabetes and intrapartum complications like abruption.Conclusions: Perinatal mortality rate serves as the most sensitive index of maternal and neonatal care. Good antenatal care and prevention of preterm birth may play a key role in further reduction of PMR.

scholarly journals Results from an International Case-Control Study of Childhood Brain Tumors: The Role of Prenatal Vitamin Supplementation

1998 ◽  
Vol 106 ◽  
pp. 887 ◽  
Author(s):  
Susan Preston-Martin ◽  
Janice M. Pogoda ◽  
Beth A. Mueller ◽  
Flora Lubin ◽  
Baruch Modan ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Case Control Study ◽  
Case Control ◽  
Vitamin Supplementation ◽  
Childhood Brain Tumors ◽  
Control Study

scholarly journals Fascin-1 and its role as a serological marker in prostate cancer: a prospective case–control study

2021 ◽  
pp. FSO745
Author(s):  
Octavian Sabin Tătaru ◽  
Orsolya Martha ◽  
Felice Crocetto ◽  
Biagio Barone ◽  
Septimiu Voidazan ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Case Control Study ◽  
Sandwich Elisa ◽  
Case Control ◽  
Elisa Method ◽  
Diagnostic Role ◽  
The Difference ◽  
Blood Specimens ◽  
Control Study

Aim: This study aims to investigate any modification of serological FSCN1 in prostate cancer patients compared with patients without neoplasia. Material & methods: Clinical data and blood specimens from patients with and without prostate cancer were obtained. A quantitative sandwich ELISA method was used to determine serological values of FSCN1. Results: Although serum values of FSCN1 were dissimilar in the two cohorts of patients (6.90 vs 7.33 ng/ml), the difference was not statistically significant (p = 0.20). Serum values of FSCN1 stratified for Gleason score groups were not significantly distinguishable (p = 0.65). A negative correlation (rho = -0.331; p = 0.009) was reported between FSCN1 and age. Conclusion: Further studies are required to evaluate a possible diagnostic role of FSCN1 in prostate cancer.

scholarly journals FAKTOR YANG MEMPENGARUHI PENERAPAN INISIASI MENYUSU DINI (IMD) DI WILAYAH KERJA PUSKESMAS JUMPANDANG BARU KOTA MAKASSAR

2020 ◽  
Vol 15 (2) ◽  
pp. 207
Author(s):  
Nurjaya Nurjaya ◽  
Djuhadiah Saadong ◽  
Subriah Subriah
Keyword(s):  
Health Center ◽  
Case Control Study ◽  
Case Control ◽  
The Philippines ◽  
Breastfeeding Initiation ◽  
Test Results ◽  
Birth Attendants ◽  
Consecutive Sampling ◽  
Control Study

ABSTRAK Latar Belakang :  IMD sangat bermanfaat bukan hanya bagi bayi yang baru lahir tetapi juga bagi ibu yang melakukan IMD. Jika bayi berada dalam dekapan ibu, maka bayi tersebut dengan sendirinya merangkak ke payudara ibu dan akan mulai menghisap puting susu ibunya. Data menunjukkan bahwa di Indonesia, persentase pemberian Air Susu Ibu (ASI) dalam 1 jam pertama setelah bayi dilahirkan masih rendah yaitu sebesar 38%. Angka tersebut masih jauh tertinggal bila dibandingkan dengan negara-negara berkembang lainnya seperti Oman (85%), Srilangka (75%), Filipina (54%), dan Turki (54%)(SDKI 2017). Oleh karena itu tujuan dari penelitian ini adalah untuk Mengetahui faktor yang mempengaruhi penerapan inisiasi menyusu dini di wilayah kerja Puskesmas Jumpandang Baru Makassar tahun 2018..Jenis penelitian ini: Penelitian ini menggunakan desain case control study. Populasi pada penelitian ini adalah semua ibu yang melahirkan di Wilayah kerja Puskesmas Jumpandang Baru. Pengambilan sampel dilakukan dengan Consecutive Sampling yaitu dengan perbandingan 1 : 2 yang dibutuhkan adalah 30 kasus dan 60 kontrol.. Pengumpulan data dilakukan menggunakan lembaran kuesioner. Data dianalisis secara univariat, bivariat dan multivariat dengan menggunakan uji Regresi Berganda LogistikHasil penelitian : Ada pengaruh pengetahuan ( OR = 5,5), peran bidan/penolong persalinan (OR = 12,571), dukungan dari suami ( OR = 3,3) terhadap penerapan inisiasi menyusu dini dan Hasil uji multivariat menunjukkan bahwa variabel peran bidan/penolong persalinan merupakan faktor yang paling berpengaruh terhadap penerapan inisiasi menyusu dini dengan nilai Wald sebesar 13 dan signifikansi sebesar 0,010.Kesimpulan : Terdapat pengaruh pengetahuan, peran bidan/penolong persalinan , dukungan dari suami terhadap penerapan inisiasi menyusu dini, dan variable peran bidan/penolong persalinan yang paling berpengaruh terhadap penerapan inisiasi menyusu dini. Kata Kunci: Penerapan Inisiasi Menyusu DiniABSTRACT Background: IMD is very beneficial not only for newborns but also for mothers who do IMD. If the baby is in the mother's arms, the baby naturally crawls into the mother's breast and will start sucking her mother's nipples. Data shows that in Indonesia, the percentage of breastfeeding in the first 1 hour after the baby is born is still low at 38%. This figure is far behind when compared to other developing countries such as Oman (85%), Sri Lanka (75%), the Philippines (54%), and Turkey (54%) (IDHS 2017) . Therefore the purpose of the research This is to find out the factors that influence the application of early breastfeeding initiation in the working area of the Jumpandang Baru Makassar Health Center in 2018 ..Type of research: This study uses a case control study design. The population in this study were all mothers who gave birth in the Working Area of the Jumpandang Baru Health Center. Sampling was done by Consecutive Sampling, which is a ratio of 1: 2. It takes 30 cases and 60 controls. Data collection is done using a questionnaire sheet. Data were analyzed by univariate, bivariate and multivariate using the Multiple Logistic Regression testResults: There was influence of knowledge (OR = 5,5), role of midwife / birth attendant (OR = 13), support from husband (OR = 3,3) on the application of early breastfeeding initiation and multivariate test results showed that the role of midwives / birth attendants was a factor the most influential on the application of early breastfeeding initiation with a Wald value of 12,956 and a significance of 0.010.Conclusion: There is an influence of knowledge, the role of midwives / birth attendants, support from husbands on the application of early breastfeeding initiation, and the role variables of midwives / birth attendants who most influence the application of early breastfeeding initiation. Keywords: Application of Early Breastfeeding Initiation 

Role of parity and human papillomavirus in cervical cancer: the IARC multicentric case-control study

The Lancet ◽  
2002 ◽  
Vol 359 (9312) ◽  
pp. 1093-1101 ◽  
Author(s):  
Nubia Muñoz ◽  
Silvia Franceschi ◽  
Cristina Bosetti ◽  
Victor Moreno ◽  
Rolando Herrero ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Allium vegetables intake and endometrial cancer risk

2009 ◽  
Vol 12 (9) ◽  
pp. 1576-1579 ◽  
Author(s):  
Carlotta Galeone ◽  
Claudio Pelucchi ◽  
Luigino Dal Maso ◽  
Eva Negri ◽  
Maurizio Montella ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Wide Spectrum ◽  
Protective Role ◽  
Case Control ◽  
Endometrial Cancer Risk ◽  
Allium Vegetables ◽  
Control Study

AbstractObjectiveThe potential role of allium vegetables on endometrial cancer risk has been scarcely investigated and the results of previous Chinese studies are not easily applicable to Western populations. Therefore, we evaluated the relationship between onion and garlic intake and endometrial cancer, using data from an Italian case–control study.SettingWe analysed data from a multi-centre case–control study of 454 endometrial cancer cases and 908 controls, admitted to the same hospitals for a wide spectrum of acute, non-neoplastic conditions. Information was collected by trained interviewers using a validated and reproducible FFQ. Multivariate odds ratios and 95 % confidence intervals were obtained after allowance for recognized confounding factors.ResultsCompared with non-users, the OR of endometrial cancer for successive categories of onion intake were 0·94 (95 % CI 0·72, 1·21) for <2 portions/week and 0·40 (95 % CI 0·22, 0·72) for ≥2 portions/week, with a significant inverse trend in risk (P = 0·01). The OR for an increment of one portion (i.e. 80 g) of onions per week was 0·81 (95 % CI 0·70, 0·95). For garlic, the OR for successive categories of intake were 0·89 (95 % CI 0·68, 1·15) for intermediate use and 0·62 (95 % CI 0·42, 0·92) for high use, with a significant inverse trend in risk (P = 0·02).ConclusionsOur study found a moderate protective role of allium vegetables on the risk of endometrial cancer.

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