scholarly journals Staphylococcus spp. in the oral cavity and periodontal pockets of chronic periodontitis patients

2004 ◽  
Vol 35 (1-2) ◽  
Author(s):  
Jussara Cia S. Loberto ◽  
Clélia Ap. de Paiva Martins ◽  
Silvana S. Ferreira dos Santos ◽  
José Roberto Cortelli ◽  
Antonio Olavo Cardoso Jorge
Keyword(s):  
Oral Cavity ◽  
Chronic Periodontitis ◽  
Staphylococcus Spp

scholarly journals In vitro minocycline activity on superinfecting microorganisms isolated from chronic periodontitis patients

2006 ◽  
Vol 20 (3) ◽  
pp. 202-206 ◽  
Author(s):  
Luciana Fernandes de Oliveira ◽  
Antonio Olavo Cardoso Jorge ◽  
Silvana Soléo Ferreira dos Santos
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Chronic Periodontitis ◽  
Periodontal Pocket ◽  
Dilution Method ◽  
Agar Dilution Method ◽  
Periodontal Pathogens ◽  
Candida Spp ◽  
Systemic Antibiotic Therapy ◽  
Staphylococcus Spp

Chronic periodontitis is the most common type of periodontitis and it is associated with various species of microorganisms. Enteric rods, Pseudomonas, Staphyloccocus and Candida have been retrieved from periodontal pockets of patients with chronic periodontitis and correlated to cases of superinfection. Local or systemic antibiotic therapy is indicated to reinforce the effects of the conventional mechanical therapy. Minocycline has been suggested as one of the most effective drugs against periodontal pathogens. The aim of this work was to evaluate the minimal inhibitory concentration (MIC) of minocycline on superinfecting microorganisms isolated from the periodontal pocket and the oral cavity of individuals with chronic periodontitis. Isolates of Enterobacteriaceae (n = 25), Staphylococcus spp. (n = 25), Pseudomonas aeruginosa (n = 9) and Candida spp. (n = 25) were included in the study. Minimal inhibitory concentrations (MIC) of minocycline were determined using the Müeller-Hinton agar dilution method. Staphylococcus spp. isolates were the most sensitive to minocycline with a MIC of 8 µg/mL, followed by Enterobacteriaceae with a MIC of 16 µg/mL. The concentration of 16 µg/mL inhibited 96% of Candida spp. isolates. The MIC for 88.8% of the isolates of Pseudomonas aeruginosa was 128 µg/mL. A concentration of 1,000 µg/mL was not enough to inhibit 100% of the tested isolates.

scholarly journals Association between Chronic Periodontitis and Oral/Oropharyngeal Cancer

2016 ◽  
Vol 27 (3) ◽  
pp. 261-266 ◽  
Author(s):  
Renata Costa de Moraes ◽  
Fernando Luiz Dias ◽  
Carlos Marcelo da Silva Figueredo ◽  
Ricardo Guimarães Fischer
Keyword(s):  
Oral Cavity ◽  
Chronic Periodontitis ◽  
Oropharyngeal Cancer ◽  
Risk Indicators ◽  
Control Group ◽  
Case Group ◽  
Pocket Depth ◽  
Clinical Attachment Loss ◽  
Probing Pocket Depth ◽  
Significant Difference

Abstract The aim of this case control study was to assess the association between the extent and severity of chronic periodontitis and oral cavity and/or oropharyngeal cancer. The case group comprised 35 patients (mean age 56.1±8.4), diagnosed for oral and/or oropharyngeal cancer. The control group comprised 40 individuals (mean age 55.4±9.4) without diagnostic of cancer. All individuals were subjected to a periodontal examination, including bleeding on probing, plaque index, gingival index, probing pocket depth (PPD), clinical attachment loss (CAL), and decayed, extracted and filled teeth index (DMFT). The case group had significantly more sites with plaque. GI and BOP had similar values in both groups. The median PPD and CAL values were significantly higher for the case group. Chronic generalized periodontitis was predominant in 80% of patients with oral and/or oropharyngeal cancer. Eighty nine percent of the patients in the case group presented severe chronic periodontitis. There was no significant difference between groups for median values of DMFT. The extent and severity of chronic periodontitis remained as risk indicators for oral cavity and/or oropharyngeal cancer even after the adjustments for traditional confound factors, i.e. smoking and alcohol consumption.

scholarly journals Presence of Staphylococcus spp. and Candida spp. in the human oral cavity

2002 ◽  
Vol 33 (3) ◽  
pp. 236-240 ◽  
Author(s):  
Clélia Aparecida de Paiva Martins ◽  
Cristiane Yumi Koga-Ito ◽  
Antonio Olavo Cardoso Jorge
Keyword(s):  
Oral Cavity ◽  
Candida Spp ◽  
Human Oral Cavity ◽  
Staphylococcus Spp

Results of clinical and laboratory research in the complex treatment of mild chronic periodontitis us-ing photodynamic therapy

2021 ◽  
pp. 33-37
Author(s):  
V.O. Samusenkov ◽  
V.N. Tsarev ◽  
E.V. Ippolitov ◽  
M.S. Podporin ◽  
K.S. Grishaeva
Keyword(s):  
Photodynamic Therapy ◽  
Oral Cavity ◽  
Chronic Periodontitis ◽  
Antimicrobial Effect ◽  
Laboratory Research ◽  
Laboratory Evaluation ◽  
Complex Treatment ◽  
Periodontal Tissues ◽  
Methods Of Treatment ◽  
Microbiological Research

The study analyzed the results of clinical evaluation of the effectiveness of photodynamic therapy for mild chronic periodontitis, as well as clinical and laboratory evaluation of the effectiveness of photodynamic therapy for this pathology, including microbiological research. Observations were carried out for a period of up to 1 year, during which photodynamic therapy proved to be one of the most effective methods of treatment that have an antimicrobial effect, which positively affects the condition of periodontal tissues, as well as has a beneficial effect on the microbiocenosis of the oral cavity.

Role of antimicrobial peptides system in inflammatory periodontal diseases non-specific oral cavity protection

2021 ◽  
Vol 66 (7) ◽  
pp. 422-427
Author(s):  
N. V. Davidovich ◽  
N. V. Solovieva ◽  
A. S. Galieva ◽  
S. Yu. Lepeshkin ◽  
E. N. Bashilova ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Antimicrobial Peptides ◽  
Chronic Periodontitis ◽  
Pathogenic Bacteria ◽  
Periodontal Diseases ◽  
Control Group ◽  
Periodontal Pathogens ◽  
Local Immunity ◽  
Microbial Invasion

The system of antimicrobial peptides (AMP) is one of the most ancient mechanisms of the macroorganism resistance to infectious pathogens invasion. The aim of the study was to determine the role of the antimicrobial peptides system and periodontal pathogenic markers in the development and progression of inflammatory periodontal diseases. Gingival pocket washes (91 samples in total) for the research were received from patients with inflammatory periodontal diseases (chronic periodontitis and gingivitis) and intact periodontium. Using ELISA, the content of antimicrobial peptides was determined: human alpha-defensin (HNP 1-3), beta-defensin (HBD 1-3) and cathelicidin (LL-37). Periodontal pathogenic markers were isolated during RT-PCR. The study revealed differences in AMP concentrations by groups: level of HBD 2 in patients with chronic periodontitis was 1,36 times higher than those in the group of patients with chronic gingivitis (p=0,023) and 2,39 times higher than those in the control group (p<0,001), the content of HNP 1-3 in the group of patients with chronic periodontitis was reduced by 1,23 times compared with the indicators of the group of patients with gingivitis (p=0,045) and by 1,97 times compared with the indicators of the control group (p<0,001). The frequency of detection of periodontal pathogenic bacteria genes was 88,0% in patients with periodontitis, 76,92% in patients with gingivitis and 33,3% in the group with intact periodontium. HBD 2 content moderately correlated with the definition of P. gingivalis (r=0,612; p=0,022), T. forsythensis (r= 0,434; p=0,015), A. actinomycetemcomitans (r=0,483; p=0,006), a moderate negative correlation was detected between the content of HNP 1-3 and the release of periodontal pathogens in associations (P. gingivalis with T. forsythensis and T. denticola) (r=-0,388; p=0,031) in the group of patients with chronic periodontitis. Thus, the revealed relationships and correlations indicate shifts in the processes of reparative regeneration of the oral cavity and the regulation of local immunity in response to microbial invasion.

scholarly journals Zoonotic potential of oral microbiota of capuchins monkeys (sapajus libidinosus)

2020 ◽  
Vol 9 (10) ◽  
pp. e1229108182
Author(s):  
Larissa Campos Rodrigues Pinheiro ◽  
Enoque Pereira Costa Sobrinho Junior ◽  
Gildevane Vieira do Nascimento ◽  
Ana Maria Quessada ◽  
Agnys Raquel Sousa Abreu ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Oral Microbiota ◽  
Zoonotic Potential ◽  
Bacterial Strains ◽  
Morganella Morganii ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
In Captivity ◽  
Staphylococcus Spp ◽  
Klebsiella Spp

Sapajus libidinosus is a species of primates, popularly known as capuchin monkey. The oral cavity of the monkeys may have pathogenic microbiota for human. Therefore, the study of the microbiota of these species is of great interest in unique health. The objective of the present article was to carry out a survey of the oral microbiota of Sapajus libidinosus, kept in captivity, in the Zoobotanical Park of Teresina (PI, Brazil). Ten chemically immobilized primates were used. Samples were collected from the oral mucosa along the maxillary muco-gingival transition, and these samples were sent to culture and microbiological identification. Most of the microorganisms found were Gram negative and E.coli was the most frequent, followed by Enterobacter spp, Klebsiella spp, Proteus mirabilis, Citrobacter spp.,Morganella morganii, as well as Gram positive bacteria of the type Staphylococcus spp. The data obtained demonstrated the presence of bacterial strains with potential risk of transmission to other animals kept in the park as well as humans in contact with these animals.

scholarly journals Prevalence of β-lactam (blaTEM) and Metronidazole (nim) Resistance Genes in the Oral Cavity of Greek Subjects

2016 ◽  
Vol 10 (1) ◽  
pp. 89-98 ◽  
Author(s):  
Georgios Koukos ◽  
Antonios Konstantinidis ◽  
Lazaros Tsalikis ◽  
Minas Arsenakis ◽  
Theodora Slini ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Antimicrobial Activity ◽  
Oral Cavity ◽  
Chronic Periodontitis ◽  
Polymerase Chain Reaction Amplification ◽  
High Rate ◽  
Clinical Parameters ◽  
Chain Reaction ◽  
Reaction Amplification ◽  
Polymerase Chain

Objectives:The aim of this study is to investigate the prevalence ofblaTEMandnimgenes that encode resistance to β-lactams and nitroimidazoles, respectively, in the oral cavity of systemically healthy Greek subjects.Materials and Methodology:After screening 720 potentially eligible subjects, 154 subjects were recruited for the study, including 50 periodontally healthy patients, 52 cases of gingivitis and 52 cases of chronic periodontitis. The clinical parameters were assessed with an automated probe. Various samples were collected from the tongue, first molars and pockets >6mm, and analysed by polymerase chain reaction-amplification of theblaTEMandnimgenes, using primers and conditions previously described in the literature.Results:There was a high rate of detection ofblaTEMin plaque and tongue samples alike in all periodontal conditions (37% of plaque and 60% of tongue samples, and 71% of participants). TheblaTEMgene was detected more frequently in the tongue samples of the periodontally healthy (56%) and chronic periodontitis (62%) groups compared to the plaque samples from the same groups (36% and 29%, respectively; z-test with Bonferroni corrections-tests,P<0.05). Thenimgene was not detected in any of the 343 samples analysed.Conclusion:The oral cavity of Greek subjects often harboursblaTEMbut notnimgenes, and therefore the antimicrobial activity of β-lactams might be compromised.

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