Selection of Rational Trends in Development of an Automated System for Controlling the Operation of Electronic Facilities Under Electronic Conflict Conditions

Researchers in the humanities almost always have to deal with the problem of statistical processing of results and their interpretation. This is a rather laborious and painstaking work, which can be greatly simplified through the use of multifunctional statistical criteria. Within the framework of the study related to the problem of self-design of educational and professional ac-tivities of students, the analysis of the effectiveness of the introduction of technological elements using multifunctional criteria was carried out: φ* criterion – Fisher’s angular transformation and binomial criterion m. The statistical significance of the results of the introduction at a certain stage of the technology of the workshop is revealed, which makes it possible to study and apply the ele-ments of self-management in the educational and professional activities of students. For promising purposes, it is proposed to create an automated system that implements the selection of the appropriate criterion for the problem to be solved and the verification of the statistical hypothesis put forward by the researcher.

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Instrumentation for automated solid phase peptide synthesis

Fmoc Solid Phase Peptide Synthesis ◽

10.1093/oso/9780199637256.003.0017 ◽

1999 ◽

Author(s):

Linda E. Cammish ◽

Steven A. Kates

Keyword(s):

Amino Acid ◽

Peptide Synthesis ◽

Solid Phase ◽

Solid Phase Peptide Synthesis ◽

Reaction Vessel ◽

Automated System ◽

Polymeric Support ◽

Simple Filtration ◽

Subsequent Activation ◽

Selection Of

The concept of solid phase peptide synthesis introduced by Merrifield in 1963 involves elongating a peptide chain on a polymeric support via a two-step repetitive process: removal of the Nα-protecting group and coupling of the next incoming amino acid. A second feature of the solid phase technique is that reagents are added in large excesses which can be removed by simple filtration and washing. Since these operations occur in a single reaction vessel, the entire process is amenable to automation. Essential requirements for a fully automatic synthesizer include a set of solvent and reagent reservoirs, as well as a suitable reaction vessel to contain the solid support and enable mixing with solvents and reagents. Additionally, a system is required for selection of specific solvents and reagents with accurate measurement for delivery to and removal from the reaction vessel, and a programmer to facilitate these automatic operations is necessary. The current commercially available instruments offer a variety of features in terms of their scale (15 mg to 5 kg of resin), chemical compatibility with 9-fluorenylmethyloxycarbonyl/tert-butyl (Fmoc/tBu) and tert-butyloxycarbonyl/ benzyl (Boc/Bzl)-based methods, software (reaction monitoring and feedback control), and flexibility (additional washing and multiple activation strategies). In addition, certain instruments are better suited for the synthesis of more complex peptides such as cyclic, phosphorylated, and glycosylated sequences while others possess the ability to assemble a large number of peptide sequences. The selection of an instrument is dependent on the requirements and demands of an individual laboratory. This chapter will describe the features of the currently available systems. As the field of solid phase synthesis evolved, manufacturers designed systems based on the synergy between chemistry and engineering. A key component to an instrument is the handling of amino acids and their subsequent activation to couple to a polymeric support. The goal of an automated system is to duplicate conditions that provide stability to reactive species that might decompose. Standard protocols for automated synthesis incorporate carbodiimide, phosphonium, and aminium/uronium reagents, preformed active esters, and acid fluorides. For further details on coupling methods, see Chapter 3. A second issue related to coupling chemistry is the time required to dissolve an amino acid and store this solution.

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Development of a modular automated system for maintenance and differentiation of adherent human pluripotent stem cells

10.1101/079335 ◽

2016 ◽

Cited By ~ 1

Author(s):

Duncan E. Crombie ◽

Maciej Daniszewski ◽

Helena H. Liang ◽

Tejal Kulkarni ◽

Fan Li ◽

...

Keyword(s):

Stem Cells ◽

Pluripotent Stem Cells ◽

Large Scale ◽

Human Pluripotent Stem Cells ◽

Automated System ◽

Patient Specific ◽

High Throughput Analysis ◽

Large Scale Culture ◽

Induced Pluripotent ◽

Selection Of

AbstractPatient-specific induced pluripotent stem cells (iPSCs) have tremendous potential for development of regenerative medicine, disease modelling and drug discovery. However, the processes of reprogramming, maintenance and differentiation are labour intensive and subject to inter-technician variability. To address these issues, we established and optimised protocols to allow for the automated maintenance of reprogrammed somatic cells into iPSCs to enable the large-scale culture and passaging of human pluripotent stem cells (PSCs) using a customized TECAN Freedom EVO. Generation of iPSCs was performed offline by nucleofection followed by selection of TRA-1-60 positive cells using a Miltenyi MultiMACS24 Separator. Pluripotency markers were assessed to confirm pluripotency of the generated iPSCs. Passaging was performed using an enzyme-free dissociation method. Proof of concept of differentiation was obtained by differentiating human PSCs into cells of the retinal lineage. Key advantages of this automated approach are the ability to increase sample size, reduce variability during reprogramming or differentiation, and enable medium to high-throughput analysis of human PSCs and derivatives. These techniques will become increasingly important with the emergence of clinical trials using stem cells.

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Social engineering in the national agriculture economy on example of dairy industry development in the Russian Federation

Agricultural Technologies ◽

10.35599/agritech/01.03.08 ◽

2019 ◽

Vol 1 (3) ◽

pp. 51-58

Author(s):

Alexey A Deshevykh ◽

Olga I. Skobel ◽

Svetlana N. Kovalchuk

Keyword(s):

Dairy Industry ◽

Social Engineering ◽

Automated System ◽

Economic Management ◽

Cattle Breeds ◽

Doing Business ◽

The Russian Federation ◽

Agricultural Business ◽

The Impact ◽

Selection Of

Issues on dairy producers’ motivation are not very obvious at the first sight. The main argument for economic activity is profit. Apparent, a large number of "pitfalls", which are subsequently found in the process of doing business, sometimes lead to a halt in the production process. Periods of change of accents in agricultural business that are typical both for the economic branch as a whole, and specifically for the dairy industry, are considered in this paper. It is worth noting that the quality and quantity of specialized information is the basis of any business. This paper considers aspects of the impact of created, destroyed or modified information modules in the field of economic management in general and the impact of information blocks on the dairy industry. The socio-engineering scheme of data collection, planned for use in the automated system of selection of cattle breeds, depending on the ecological and geographical conditions of the breeding region, is proposed in this work. Algorithm of information processes of the designated system with methods of social engineering is formed. This algorithm is designed to collect data on specific and time-stable features of different cattle breeds.

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An automatic wavelet denoising scheme for heart sounds

International Journal of Wavelets Multiresolution and Information Processing ◽

10.1142/s0219691315500162 ◽

2015 ◽

Vol 13 (03) ◽

pp. 1550016 ◽

Cited By ~ 8

Author(s):

Tahar Omari ◽

Fethi Bereksi-Reguig

Keyword(s):

Heart Diseases ◽

Heart Sounds ◽

Automated System ◽

Mother Wavelet ◽

Electronic Stethoscope ◽

Novel Approach ◽

Breath Sounds ◽

Many Sources ◽

Pcg Signals ◽

Selection Of

Phonocardiograms (PCGs), recording of heart sounds, have many advantages over traditional auscultation in that they may be replayed and analyzed for spectral and frequency information. PCG is not a widely used diagnostic tool as it could be. One of the major problems with PCG is noise corruption. Many sources of noise may pollute a PCG signal including lung and breath sounds, environmental noise and blood flow noises which are known as murmurs. These murmurs contain many information on heart hemodynamic which can be used particularly in detecting of heart valve diseases. An automated system for heart murmurs processing can be an important tool in diagnostic of heart diseases using a simple electronic stethoscope. However, the first step before developing any automated system is the segmentation of the PCG signals from which the murmurs can be separated. A robust segmentation algorithm must have a robust denoising technique, where, wavelet transform (WT) is among the ones which exhibits very high satisfactory results in such situations. However, the selection of level of decomposition and the mother wavelet are the major challenges. This paper proposes a novel approach for an automatic selection of mother wavelet and level of decomposition that can be used in heart sounds denoising. The obtained results on both simulative and real PCG signals showed that the proposed approach can successfully select the best level of decomposition with the best mother wavelet that can be used in extraction operation of main PCG sound components (S1 and S2) from various types of murmurs.

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FORMALIZATION OF THE PROBLEM OF SELECTION OF AUTOMATED SYSTEM

«System analysis and applied information science» ◽

10.21122/2309-4923-2018-1-16-20 ◽

2018 ◽

pp. 16-20

Author(s):

A. V. Petukhov

Keyword(s):

Economic Effect ◽

Operating Conditions ◽

Automated System ◽

Qualitative Assessment ◽

Automated Systems ◽

Customer Requirements ◽

Qualitative And Quantitative ◽

Complete Restoration ◽

Selection Of

The results of many years of research in the field of formalizing the task of selecting automated systems for various areas of design and office activities are given. The purpose of the study is the development of methods for qualitative and quantitative evaluation when choosing an automated system, taking into accounts the operating conditions and customer requirements. Qualitative assessment is based on the theory of choice and decision making, which examines the mathematical models of this type of activity. In view of the fact that in the problem under consideration, many alternatives, which are automated systems, are known, it can be related to the choice problem. The peculiarity of this approach is that it does not require a complete restoration of the principle of optimality, but allows us to confine ourselves to information sufficient to identify the optimal variant. The quantitative assessment is based on the determination of the projected annual economic effect from the introduction of an automated system. The described technique can be used by enterprises and organizations in the evaluation of automated systems at the stage preceding the tender for their purchase.

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SEARCH OF OPTIMAL COMPROMISE BETWEEN REQUIREMENTS IN SPHERE OF INFORMATION PROCESSING AND RESOURCES REQUIRED FOR THESE TASKS

Issues of radio electronics ◽

10.21778/2218-5453-2019-1-78-81 ◽

2019 ◽

pp. 78-81

Author(s):

N. Yu. Kovalchuk

Keyword(s):

Information Processing ◽

Integrated Assessment ◽

System Analysis ◽

Objective Assessment ◽

Automated System ◽

Processing Strategy ◽

Complex Information ◽

Optimal Information ◽

Information Processing Strategy ◽

Selection Of

The possibility of using the fundamentals of system analysis when choosing the optimal information processing strategy in the design of complex information systems with the aim of obtaining a complete and objective assessment of information resources, implemented in the interest of analyzing the technical characteristics of integrated information processing tools of complex automated systems, is considered. Information risk analysis was carried out, i.e. the process of integrated assessment of information processing in an automated system with the transition to quantitative or qualitative indicators. In addition, each indicator represents the probable damage, which depends on the information processing in the system. The process of identifying and reducing risks that can affect the information system is understood as the process of risk management. The results of the analysis are used in the selection of information processing facilities and in evaluating the effectiveness of existing and projected subsystems.

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Communications Management by the Remote System—An Adaptive Approach

Proceedings of the Human Factors Society Annual Meeting ◽

10.1177/107118137702100610 ◽

1977 ◽

Vol 21 (6) ◽

pp. 495-500

Author(s):

Randall Steeb ◽

Denis Purcell

Keyword(s):

Pattern Recognition ◽

Computer Program ◽

Decision Model ◽

Automated System ◽

Training Algorithm ◽

Adaptive Approach ◽

Pattern Recognition Techniques ◽

State Operator ◽

Remote System ◽

Selection Of

Management of communications between a remote or automated system and a supervisory human operator can be a formidable task. The selection of information for transmission is a recurrent, subjective decision involving many factors – machine state, operator capabilities, communications costs, and channel limitations, among others. An adaptive computer program has been developed which incorporates these various factors into a decision model resident in the remote element. The program is designed to capture the supervisory operator's decision policy by using a training algorithm based on pattern recognition techniques. Some exploratory studies of the technique are described.

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Optimum Design of Hydrodynamic Journal Bearings

Journal of Lubrication Technology ◽

10.1115/1.3554974 ◽

1969 ◽

Vol 91 (3) ◽

pp. 516-521 ◽

Cited By ~ 17

Author(s):

A. Seireg ◽

H. Ezzat

Keyword(s):

Journal Bearing ◽

Journal Bearings ◽

Automated System ◽

Optimal Programming ◽

Programming Techniques ◽

Design Systems ◽

Hydrodynamic Journal Bearing ◽

Bearing Design ◽

Lubricant Viscosity ◽

Selection Of

This paper presents an automated system for the selection of the length, clearance, and lubricant viscosity which optimize the performance of a hydrodynamic journal bearing, under specified values or ranges of load and speed. The study illustrates the feasibility of applying optimal programming techniques for the development of bearing design systems.

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