scholarly journals Synthesis, Characterization and Crystal Structures of Schiff Base Copper Complexes with Urease Inhibitory Activity

2021 ◽  
Vol 68 (4) ◽  
pp. 961-969
Author(s):  
Shuang Han ◽  
Yuan Wang
Keyword(s):  
Copper Complexes ◽  
Molar Conductivity ◽  
X Ray Diffraction ◽  
Inhibitory Effects ◽  
X Ray ◽  
Effective Activity ◽  
Square Planar ◽  
Vis Spectroscopy ◽  
Elemental Analyses ◽  
Urease Inhibitory

Urease inhibitors can inhibit the decomposition rate of urea, and decrease the air pollution caused by ammonia. In this paper, four new copper(II) complexes [CuL(ONO2)]n (1), [Cu2L2(μ1,3-N3)2] (2), [CuBrL] (3), and [CuClL] (4), where L = 5-bromo-2-(((2-methylamino)ethyl)imino)methyl)phenolate, have been synthesized and characterized. The complexes were characterized by elemental analyses, IR and UV-Vis spectroscopy, molar conductivity, and single crystal X-ray diffraction. X-ray analysis reveals that Cu atoms in complexes 1 and 2 are in square pyramidal coordination, and those in complexes 3 and 4 are in square planar coordination. The molecules of the complexes are linked through hydrogen bonds and π···π interactions. The inhibitory effects of the complexes on Jack bean urease were studied, which showed that the complexes have effective activity on urease.

scholarly journals Copper(II) and Zinc(II) Complexes Derived from N,N’-Bis(4-bromosalicylidene)propane-1,3-diamine: Syntheses, Crystal Structures and Antimicrobial Activity

2021 ◽  
Vol 68 (1) ◽  
pp. 102-108
Author(s):  
Yu-Mei Hao
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Activity ◽  
Candida Parapsilosis ◽  
Antibacterial Activities ◽  
X Ray Diffraction ◽  
Deprotonated Form ◽  
X Ray ◽  
Square Planar ◽  
Vis Spectroscopy ◽  
Elemental Analyses

A mononuclear copper(II) complex, [CuL] (1), and a phenolato-bridged trinuclear zinc(II) complex, [Zn3Cl2L2(DMF)2] (2), where L is the deprotonated form of N,N’-bis(4-bromosalicylidene)propane-1,3-diamine (H2L), have been prepared and characterized by elemental analyses, IR and UV-Vis spectroscopy, and single crystal X-ray diffraction. The Cu atom in complex 1 is in square planar coordination, while the terminal and central Zn atoms in complex 2 are in square pyramidal and octahedral coordination, respectively. The antibacterial activities of the complexes have been tested on the bacteria Staphylococcus aureus and Escherichia coli, and the yeast Candida parapsilosis.

Bimetallomesogens: Synthesis and Mesomorphic Properties of Coppercomplexes of 3,3'-(2-hydroxypropane-1,3-diyl)bis(azan-1- yl-1-ylidene)bis(2-(4-alkoxyphenyl)prop-1-en-1-ol)

2010 ◽  
Vol 428-429 ◽  
pp. 140-143
Author(s):  
Chung Jung Chen ◽  
Chung K. Lai
Keyword(s):  
Copper Complexes ◽  
Crystallographic Analysis ◽  
Planar Geometry ◽  
X Ray Diffraction ◽  
Scanning Calorimetry ◽  
X Ray ◽  
Square Planar ◽  
New Type ◽  
Optical Textures ◽  
Mesomorphic Properties

A new type of 3,3'-(2-hydroxypropane-1,3-diyl) bis(azan-1-yl-1-ylidene)bis(2-(4-alkoxy phenyl)prop-1-en-1-ol) and their copper complexes were prepared and mesomorphic properties characterized. The mesomorphic properties of these copper complexes were studied by differential scanning calorimetry (DSC), polarized optical microscopy (POM) and powder X-ray diffraction. X-ray structural crystallographic analysis showed that these bimetallic compounds have two copper centers coordinated with central square planar geometry. These molecules all have total two 1a or five alkoxy sidechains 1b appended around the central core. The mesomorphic behavior exhibited was found to be dependent on the sidechain density. All compounds in 1a exhibited smectic mesophases, however, compounds in 1b exhibited hexagonal columnar phases (Colh), which were characterized by optical textures and confirmed by powder x-ray diffraction.

scholarly journals Synthesis, Characterization, Crystal Structures, and Urease Inhibition of Copper(II) and Zinc(II) Complexes Derived from Benzohydrazones

2020 ◽  
Vol 67 (4) ◽  
pp. 1155-1162
Author(s):  
Fu-Ming Wang ◽  
Li-Jie Li ◽  
Guo-Wei Zang ◽  
Tong-Tong Deng ◽  
Zhong-Lu You
Keyword(s):  
Single Crystal ◽  
Urease Inhibition ◽  
X Ray Diffraction ◽  
Inhibitory Effects ◽  
Strong Activity ◽  
X Ray ◽  
Trigonal Bipyramidal ◽  
Metal Atoms ◽  
Vis Spectroscopy ◽  
Crystal Structural

A new copper(II) complex [Cu(L1)(NCS)(CH3OH)] (1) and a new zinc(II) complex [ZnCl2(HL2)] · CH3OH (2), derived from 4-bromo-N’-(pyridin-2-ylmethylene)benzohydrazide (HL1) and 4-methoxy-N’-(pyridin-2-ylmethylene)benzohydrazide (HL2), were prepared and characterized by elemental analysis, IR and UV-Vis spectroscopy and single crystal X-ray diffraction. The hydrazone HL1 coordinates to the Cu atom in enolate form, while the hydrazone HL2 coordinates to the Zn atom in carbonyl form. Single crystal structural analyses indicate that the hydrazones coordinate to the metal atoms through the pyridine N, imino N, and enolate/carbonyl O atoms. The Cu atom in complex 1 is in square pyramidal coordination, and the Zn atom in complex 2 is in trigonal-bipyramidal coordination. The inhibitory effects of the complexes on Jack bean urease were studied, which show that the copper complex has strong activity on urease.

scholarly journals Unprecedented Dinuclear CuII N,O-Donor Complex: Synthesis, Structural Characterization, Fluorescence Property, and Hirshfeld Analysis

Crystals ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 607 ◽  
Author(s):  
Yin-Xia Sun ◽  
Ying-Qi Pan ◽  
Xin Xu ◽  
Yang Zhang
Keyword(s):  
Crystallographic Analysis ◽  
Hirshfeld Surface ◽  
Planar Geometry ◽  
Supramolecular Network ◽  
X Ray Diffraction ◽  
Tetragonal Pyramid ◽  
X Ray ◽  
Square Planar ◽  
Elemental Analyses ◽  
Hirshfeld Analysis

An unprecedented dinuclear CuII complex, [Cu2(L2)2], derived from a salamo-like chelating ligand H2L2, was produced by the cleavage of a newly synthesized, half-salamo-like ligand HL1 (2-[O-(1-ethyloxyamide)]oxime-3,5-dichloro-phenol). This was synthesized and characterized by elemental analyses, IR, UV–Vis and fluorescent spectra, single crystal X-ray diffraction analysis, and Hirshfeld surface analysis. X-ray crystallographic analysis indicated that the two CuII (Cu1 and Cu2) ions bore different (N2O3 and N2O2) coordination environments, the penta-coordinated Cu1 ion possessed a slightly twisted tetragonal pyramid geometry with the τ value τ = 0.004, and the tetra-coordinated Cu2 ion showed a slightly twisted square planar geometry. Interestingly, one oxime oxygen atom participated in the coordination reported previously. Moreover, an infinite two-dimensional layered supramolecular network was formed. Compared with HL1, the CuII complex possessed the characteristic of fluorescence quenching.

scholarly journals Synthesis, Spectral Characterization and X–Ray Diffraction Studies of some Pd(II) Complexes with Schiff Bases

2014 ◽  
Vol 36 ◽  
pp. 272-280
Author(s):  
Julekha A. Shaikh
Keyword(s):  
Thermal Analysis ◽  
Schiff Bases ◽  
Molar Conductivity ◽  
Planar Geometry ◽  
Monoclinic Crystal System ◽  
X Ray Diffraction ◽  
Monoclinic Crystal ◽  
X Ray ◽  
Square Planar ◽  
Metal Ligand

The synthesis, spectroscopic and X – Ray Diffraction studies of some Pd(II) complexes with bidentate Schiff bases are reported here. These Schiff bases were derived by condensing aldehydes like 2-hydroxy-1-naphthaldehyde, 5-chloro salicyladehyde with amines like 4-nitro aniline, 4-methyl aniline and 4-methoxy aniline. The complexes were characterized on the basis of elemental analysis, molar conductivity, spectral (IR, 1H and electronic) as well as thermal analysis. All the Pd (II) complexes exhibit square planar geometry with 1:2 (metal : ligand) stoichiometry. The X- ray diffraction studies suggest monoclinic crystal system for these complexes.

scholarly journals Zinc Complexes Derived from 5-Bromo-2-(((2-isopropylamino)ethyl)imino)methyl)phenol: Microwave-Assisted Synthesis, Characterization, Crystal Structures and Antibacterial Activities

2021 ◽  
Vol 68 (4) ◽  
pp. 921-929
Author(s):  
Wei-Guang Zhang ◽  
Ji-Hong Liang
Keyword(s):  
Antibacterial Activities ◽  
Molar Conductivity ◽  
Zinc Complexes ◽  
Microwave Assisted Synthesis ◽  
Tetrahedral Coordination ◽  
X Ray Diffraction ◽  
X Ray ◽  
Microwave Assisted ◽  
Elemental Analyses

Three new zinc complexes [Zn3L2(μ2-η1:η1-CH3COO)2(μ2-η2:η0-CH3COO)2] (1), [ZnCl2(HL)] (2) and [ZnBr2(HL)] (3), where L = 5-bromo-2-(((2-isopropylamino)ethyl)imino)methyl)phenolate, HL = 5-bromo-2-(((2-isopropylammonio) ethyl)imino)methyl)phenolate, have been synthesized under microwave irradiation. The complexes were characterized by elemental analyses, IR, UV-Vis spectra, molar conductivity, and single crystal X-ray diffraction. X-ray analysis revealed that the Zn atoms in complex 1 are in square pyramidal and octahedral coordination, and those in complexes 2 and 3 are in tetrahedral coordination. The molecules of the complexes are linked through hydrogen bonds and π···π interactions. In order to evaluate the biological activity of the complexes, in vitro antibacterial against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa was assayed.

scholarly journals A series of Keggin- and Wells-Dawson-polyoxometalate-based compounds constructed from oxygen-functional imidazole derivatives

2019 ◽  
Vol 74 (2) ◽  
pp. 159-169 ◽  
Author(s):  
Jun Ying ◽  
Hai-Chen Mou ◽  
Jia-Ni Liu ◽  
Gui-Ying Liu ◽  
Xue-Bin Ji ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Layer Structure ◽  
X Ray Diffraction ◽  
X Ray ◽  
Imidazole Derivatives ◽  
Hydrogen Bonding Interactions ◽  
Square Planar ◽  
Elemental Analyses ◽  
Photocatalytic Activities ◽  
A Chain

AbstractThrough the use of two kinds of imidazole derivatives containing different O-functional units, three new Keggin- and one Wells-Dawson-polyoxometalate (POM)-based compounds, namely [Cu2La4(HPW12O40)] (1), [CuLa4(H2O)2(HPMo12O40)] (2), [Cu2La7(H2O)(H2P2W18O62)]·La(3), [Ag2(Lb4)(HPMo12O40)]·Lb·H2O (4)(La= (4-(2,5-dihydro-1H-imidazol-1-yl)benzaldehyde), and Lb=(4-(2,5-dihydro-1H-imidazol-1-yl)benzoic acid), were synthesized and characterized using single-crystal X-ray diffraction, elemental analyses, and infrared spectroscopy. The polyoxoanions occupy holes framed by two symmetrically oriented CuLa2 units in 1. In compound 2, the square-planar CuLa4 units form a two-dimensional (2D), supramolecular grid through π···π stacking interactions. The POMs occupy vacancies in this grid. In compound 3, the CuLa3 subunits connect the neighboring P2W18 units and an “S”-type chain is formed. Through hydrogen bonding interactions, the chains are connected to form a layer. In compound 4, the POM anions are linked by AgLb2 subunits to form a chain. All the chains are tied together to construct a layer structure with weak hydrogen bonding interactions between the terminal carboxylic acid functional groups of ligands Lb. The electrocatalytic and photocatalytic activities of all these four compounds were also studied.

scholarly journals Copper(II) Complexes of 2-(Methylthiomethyl)anilines: Spectral and Structural Properties and In Vitro Antimicrobial Activity

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Temitope E. Olalekan ◽  
Denzil R. Beukes ◽  
Bernardus Van Brecht ◽  
Gareth M. Watkins
Keyword(s):  
Antimicrobial Activity ◽  
Electronic Spectra ◽  
Copper Complexes ◽  
Structural Formula ◽  
Bidentate Ligand ◽  
X Ray Diffraction ◽  
X Ray ◽  
X Ray Crystallography ◽  
Elemental Analyses

Copper(II) complexes of 2-(methylthiomethyl)anilines (1a–1f) have been obtained and characterized by elemental analyses, IR, electronic spectra, conductivity, and X-ray crystallography. The complexes (2a–2f) have the structural formula [CuCl2L] with the bidentate ligand coordinating through sulfur and nitrogen. The single crystal X-ray diffraction data reveal that the copper complex (2f) has a tetragonally distorted octahedral structure with long Cu–Cl equatorial bonds. Magnetic susceptibility measurements indicate the availability of one unpaired electron in the complexes and the conductivity measurements in DMF show their behaviour as nonelectrolytes. The solid reflectance spectra and the electronic spectra of the complexes in DMSO were determined. The ligands and their copper complexes were screened for in vitro antimicrobial activity against S. aureus, B. subtilis, E. coli, and C. albicans. The methoxysubstituted complex (2c) showed more promising antibacterial activity against S. aureus and B. subtilis than other compounds at the concentration tested.

Synthesis and Structure of a Clathrated Two-Dimensional Metal-Organic Framework: [Cd(4,4'-bpy)2(H2O)2](ClO4)2·(L)2·H2O (L = Bis(1-pyrazinylethylidene)hydrazine)

2008 ◽  
Vol 73 (1) ◽  
pp. 24-31
Author(s):  
Dayu Wu ◽  
Genhua Wu ◽  
Wei Huang ◽  
Zhuqing Wang
Keyword(s):  
Metal Organic Framework ◽  
Channel Structure ◽  
Two Dimensional ◽  
X Ray Diffraction ◽  
Guest Molecules ◽  
X Ray ◽  
Square Planar ◽  
Metal Organic ◽  
Aqueous Meoh ◽  
Organic Framework

The compound [Cd(4,4'-bpy)2(H2O)2](ClO4)2·(L)2 was obtained by the reaction of Cd(ClO4)2, bis(1-pyrazinylethylidene)hydrazine (L) and 4,4'-bipyridine in aqueous MeOH. Single-crystal X-ray diffraction has revealed its two-dimensional metal-organic framework. The 2-D layers superpose on each other, giving a channel structure. The square planar grids consist of two pairs of shared edges with Cd(II) ion and a 4,4'-bipyridine molecule each vertex and side, respectively. The square cavity has a dimension of 11.817 × 11.781 Å. Two guest molecules of bis(1-pyrazinylethylidene)hydrazine are clathrated in every hydrophobic host cavity, being further stabilized by π-π stacking and hydrogen bonding. The results suggest that the hydrazine molecules present in the network serve as structure-directing templates in the formation of crystal structures.

Synthesis of 4-(3-coumarinyl)-3-benzyl-4-thiazolin-2-one 4-methylbenzylidenehydrazone and determination of the isomeric structure by X-ray analysis

2003 ◽  
Vol 218 (12) ◽  
Author(s):  
Süheyla Özbey ◽  
Nilgün Karalı ◽  
Aysel Gürsoy
Keyword(s):  
Single Crystal ◽  
Diffraction Analysis ◽  
Spectral Data ◽  
X Ray Diffraction ◽  
X Ray ◽  
Isomeric Structure ◽  
Elemental Analyses

AbstractIn this study 4-(3-coumarinyl)-3-benzyl-4-thi azolin-2-one 4-methylbenzylidenehydrazone 3 was synthesised. An independent proof of the thiazolylhydrazone structure of 3 was achieved by single crystal X-ray diffraction analysis. Elemental analyses and spectral data (IR,

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