scholarly journals Research progress of near-infrared fluorescence immunoassay

2019 ◽  
pp. 001-007
Author(s):  
Ma Ai Jin
Keyword(s):  
Rapid Detection ◽  
Near Infrared ◽  
Infrared Detection ◽  
Research Progress ◽  
Recent Improvement ◽  
Basic Principles ◽  
Detection Technology ◽  
Food Borne ◽  
Highly Sensitive ◽  
Application Potential

Near-infrared fl uorescence immunoassay has been widely studied in the bio analytical fi eld. This review mainly introduces the basic principles of near-infrared spectroscopy and near-infrared detection technology, and summarizes the properties, characteristics and recent improvement of optical properties and signal intensity of three near-infrared fl uorescence probes (i.e. organic fl uorophores, quantum dots and rare earth compounds). We describe the applications of near-infrared fl uorescence technology in immunoassay, and prospect the application potential of lateral fl ow assay (LFA) based on this probe in the rapid detection of pathogens. Our team intends to establish a new platform which has highly sensitive near-infrared fl uorescence probes (NIFPs) combined with portable and simple immunochromatographic test strips (ICTSs) for rapid detection of food borne viruses. This will provide technical support for a rapid detection on the port.

scholarly journals Research Progress of Near-Infrared Fluorescence Immunoassay

Micromachines ◽  
2019 ◽  
Vol 10 (6) ◽  
pp. 422 ◽  
Author(s):  
Xiao-Hui Chang ◽  
Jie Zhang ◽  
Lin-Huan Wu ◽  
Yan-Kun Peng ◽  
Xiang-Ying Yang ◽  
...  
Keyword(s):  
Rapid Detection ◽  
Near Infrared ◽  
Fluorescent Dyes ◽  
Fluorescence Probes ◽  
Research Progress ◽  
Near Infrared Fluorescence ◽  
Detection Technology ◽  
Food Borne ◽  
Bio Imaging ◽  
Walled Carbon Nanotubes

Near-infrared fluorescence probes (NIFPs) have been widely used in immunoassay, bio-imaging and medical diagnosis. We review the basic principles of near-infrared fluorescence and near-infrared detection technology, and summarize structures, properties and characteristics of NIFPs (i.e., cyanines, xanthenes fluorescent dyes, phthalocyanines, porphyrin derivates, single-walled carbon nanotubes (SWCNTs), quantum dots and rare earth compounds). We next analyze applications of NIFPs in immunoassays, and prospect the application potential of lateral flow assay (LFA) in rapid detection of pathogens. At present, our team intends to establish a new platform that has highly sensitive NIFPs combined with portable and simple immunochromatographic test strips (ICTSs) for rapid detection of food-borne viruses. This will provide technical support for rapid detection on the port.

scholarly journals Vibrational Spectroscopy in Assessment of Early Osteoarthritis—A Narrative Review

2021 ◽  
Vol 22 (10) ◽  
pp. 5235
Author(s):  
Chen Yu ◽  
Bing Zhao ◽  
Yan Li ◽  
Hengchang Zang ◽  
Lian Li
Keyword(s):  
Early Diagnosis ◽  
Vibrational Spectroscopy ◽  
Near Infrared ◽  
Early Stage ◽  
Diagnostic Methods ◽  
Research Progress ◽  
Nondestructive Technique ◽  
Promising Tool ◽  
Detection Technology ◽  
Early Oa

Osteoarthritis (OA) is a degenerative disease, and there is currently no effective medicine to cure it. Early prevention and treatment can effectively reduce the pain of OA patients and save costs. Therefore, it is necessary to diagnose OA at an early stage. There are various diagnostic methods for OA, but the methods applied to early diagnosis are limited. Ordinary optical diagnosis is confined to the surface, while laboratory tests, such as rheumatoid factor inspection and physical arthritis checks, are too trivial or time-consuming. Evidently, there is an urgent need to develop a rapid nondestructive detection method for the early diagnosis of OA. Vibrational spectroscopy is a rapid and nondestructive technique that has attracted much attention. In this review, near-infrared (NIR), infrared, (IR) and Raman spectroscopy were introduced to show their potential in early OA diagnosis. The basic principles were discussed first, and then the research progress to date was discussed, as well as its limitations and the direction of development. Finally, all methods were compared, and vibrational spectroscopy was demonstrated that it could be used as a promising tool for early OA diagnosis. This review provides theoretical support for the application and development of vibrational spectroscopy technology in OA diagnosis, providing a new strategy for the nondestructive and rapid diagnosis of arthritis and promoting the development and clinical application of a component-based molecular spectrum detection technology.

Application of Infrared Method for Water Detection in Karst Tunnel

2013 ◽  
Vol 838-841 ◽  
pp. 1387-1392 ◽  
Author(s):  
Xin Ming Guo ◽  
Ge Cui ◽  
Ya Peng Fu ◽  
Yong Fang
Keyword(s):  
Infrared Detection ◽  
Karst Tunnel ◽  
Basic Principles ◽  
Great Opportunity ◽  
Water Detection ◽  
Detection Technology ◽  
Geological Conditions ◽  
Karst Areas ◽  
Geological Prediction ◽  
Infrared Method

Water rush and mud rush are two major problems during the process of tunnel construction, which can lead to big troubles. Advanced geological prediction should be carried out to prevent the emergency of water rush and mud rush during the construction in the karst and water-rich areas. Infrared detection technology is a way to detect the hidden water. In this paper, basic principles of model HY-304 infrared detection meter are described, and it is applied in Shuangbei Tunnel. By analyzing the predicted results and comparing it with the situation of excavation, the instrument is feasible as to water rush in karst areas and infrared detection technology has a great opportunity to be applied in the tunnel engineering under complex geological conditions.

PbS QD-based photodetectors: future-oriented near-infrared detection technology

2021 ◽  
Author(s):  
Xingtian Yin ◽  
Cong Zhang ◽  
Yuxiao Guo ◽  
Yawei Yang ◽  
Yonglei Xing ◽  
...  
Keyword(s):  
Near Infrared ◽  
Low Cost ◽  
Infrared Detection ◽  
High Quality ◽  
Military Industry ◽  
Detection Technology ◽  
Medical Health ◽  
Increasing Demand

With the increasing demand for near-infrared (NIR) detection in the fields of automation, military industry, communications and medical health, how to develop novel high quality and low cost NIR photodetectors has become a research hotspot in recent years.

scholarly journals High-performance near-infrared photodetectors based on gate-controlled graphene–germanium Schottky junction with split active junction

Nanophotonics ◽  
2022 ◽  
Vol 0 (0) ◽  
Author(s):  
Cihyun Kim ◽  
Tae Jin Yoo ◽  
Min Gyu Kwon ◽  
Kyoung Eun Chang ◽  
Hyeon Jun Hwang ◽  
...  
Keyword(s):  
Dark Current ◽  
Interfacial Layer ◽  
High Performance ◽  
Near Infrared ◽  
Infrared Detection ◽  
Schottky Junction ◽  
Internal Electric Field ◽  
Detection Capability ◽  
Junction Device ◽  
Highly Sensitive

Abstract The structure of a gate-controlled graphene/germanium hybrid photodetector was optimized by splitting the active region to achieve highly sensitive infrared detection capability. The strengthened internal electric field in the split active junctions enabled efficient collection of photocarriers, resulting in a responsivity of 2.02 A W−1 and a specific detectivity of 5.28 × 1010 Jones with reduced dark current and improved external quantum efficiency; these results are more than doubled compared with the responsivity of 0.85 A W−1 and detectivity of 1.69 × 1010 Jones for a single active junction device. The responsivity of the optimized structure is 1.7, 2.7, and 39 times higher than that of previously reported graphene/Ge with Al2O3 interfacial layer, gate-controlled graphene/Ge, and simple graphene/Ge heterostructure photodetectors, respectively.

Highly Sensitive Near-Infrared Imaging of Peroxynitrite Fluxes in Inflammation Progress

2021 ◽  
Vol 93 (5) ◽  
pp. 3035-3041
Author(s):  
Zhao Wang ◽  
Weiwei Wang ◽  
Pengzhan Wang ◽  
Xinjian Song ◽  
Zhiqiang Mao ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Imaging ◽  
Near Infrared Imaging ◽  
Highly Sensitive

scholarly journals Enhanced red and near infrared detection in flow cytometry using avalanche photodiodes

2008 ◽  
Vol 73A (8) ◽  
pp. 767-776 ◽  
Author(s):  
William G. Lawrence ◽  
Gyula Varadi ◽  
Gerald Entine ◽  
Edward Podniesinski ◽  
Paul K. Wallace
Keyword(s):  
Flow Cytometry ◽  
Near Infrared ◽  
Avalanche Photodiodes ◽  
Infrared Detection
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