scholarly journals Correction of a rare malformation of the penis in two boys with a single cavernous body and classical bladder extrophy

2021 ◽  
Vol 22 (2) ◽  
pp. 84-91
Author(s):  
Yu. E. Rudin ◽  
D. V. Maruhnenko ◽  
A. Yu. Rudin ◽  
D. K. Aliev ◽  
A. B. Vardak ◽  
...  

Bladder extrophy - is a difficult malformation for the treatment. Aplasia of one of the cavernous bodies of the penis is an extremely rare pathology. In the available literature, we did not meet reports of correction of bladder extrophy in children with a single cavernous body of the penis.From 1990 to 2020, 545 children (364 boys) with extrophy have been repair. Two (0.5 %) boys only had a classic bladder extrophy combined with the aplasia of one cavernous body. The first patient with classical extrophy and multiple malformations (fingers of the right hand, fingers of the right foot, aplasia of the left kidney, left cavernous body, left testicle and hypoplasia of the left half of the scrotum) the penis with the single cavernous body on the right was somewhat thinner, but formed anatomically correctly with the presence of a urethra and closed prepuce. The primary closure of the bladder was performed with bilateral iliac osteotomy and the joint of pelvic bones at the age of 1 year. The patient had the anatomically properly formed bladder sphincter and urethra, penile correction was not required. After the operation, urinary continence had been achieved.The second boy was with classical extrophy and epispadia of the single cavernous body, he was given stage treatment. At the age of 5 days (2004) the primary closure of the bladder and the connection of the pelvic bones were performed. At the age of 4 years (2008) the formation of the urethra was carried out, the correction of the dorsal deformation of the single cavernous body by excision of the chord and the application of multiple superficial cross-cutting on the tunica albuginea. Bladder neck plastic by Kelly technique in combination with bilateral osteotomy of pelvic bones was performed at the age of 7 years in (2011). The boy of 15 years (2019) had a bladder volume of 350-400 ml. Dry 4-5 hours. Urinate freely with a wide stream. Then a two-stage plastic of the distal urethra was performed. We used the Bracka technique with augmentation of the glans penis and implantation a free graft of the mucous lip. We achieved a good result.Using modern penile correction technologies help to socially adapt patients with rare and difficult malformations.

2019 ◽  
Vol 47 ◽  
Author(s):  
Isabel Oliveira Cosentino ◽  
Mario Felipe Alvarez Balaro ◽  
Ana Beatriz Da Silva Carvalho ◽  
Juliane Teramachi Trevizan ◽  
Felipe Zandonadi Brandão ◽  
...  

Background: Seminomas are germ cell tumors mainly originating from spermatogonia in the seminiferous tubules and has been described in several domestic animal species, even though has rarely been described in goats. Moreover, seminomas tumors are not usually metastatic and rarely trigger paraneoplastic syndrome. In this sense, this is a case report of a 12-year-old male Alpine goat, suspected of testicular neoplasm based on clinical examination and ultrasound imaging, diagnosed as a seminoma with metastasis in liver by histopathology upon necropsy.Case: A 12-year-old male Alpine goat presented a 10 month history of progressive weight loss, prostration, and scrotal sac enlargement. The major clinical findings were pale conjunctival mucus, bilateral nasal catarrhal secretion, obstructive dyspnea, an increased abdominal component, crackling at trachea auscultation, silence upon lung auscultation of the ventral area and wheezing upon auscultation of the dorsal area, and enlargement of the left testicle with contralateral atrophy. At the Ultrasonography scan, the enlarged left testicle presented architecture loss, as well as circumscribed masses differing in echogenicity and echotexture with scattered small hyperechoic nodules. The shrunken right testicle showed acoustic shading across the surface suggestive of calcification. Due to the poor prognosis and regard for animal welfare, the goat was euthanized. The main necropsy findings on testicles were: enlarged left testicle with white parenchyma on the dorsal side as well as diffuse yellow elliptical lesions of 0.5-2.5 cm on the surface in association with two circumscribed areas at the cranial and caudal poles, firm upon cutting. The right testicle was half the typical size, slightly pale, firm at cutting of the tunica albuginea, and presented dark parenchyma with abundant calcification dots suggestive of microlithiasis. The histological findings included diffuse tumoral stroma of the left testicle composed of large, polyhedral, discretely demarcated circular cells exhibiting a large nucleus varying in size with little cytoplasm and a high mitotic rate. The right testicle exhibited areas of necrosis and fibrosis of the testicular parenchyma, contiguous with the area of degeneration and normal parenchyma, caseous necrosis, and focal calcification. The liver presented some foci of the same cellular pattern of the seminoma, as described in the parenchyma. The findings summarized at necropsy and histopathological evaluation were seminoma in the left testicle, with metastasis to the liver; degeneration and necrosis of the right testicle with abscess and calcification.Discussion: Seminoma has been described in several species, even though rarely in goats. This report was the second ever seminoma reported in caprine species, and particularly this case presented liver metastasis, showing the pathologic potential of this neoplasia for this species, and it differed from first reported which described ulcerative lesions in, and adhesion of the skin covering the testis. Regarding the US scan, even though this technique cannot be considered as a conclusive diagnostic, it may help to reach a prognosis by the tumor’s characteristics. An US scan along with cytology or biopsy enables an earlier diagnosis of testicular lesions and prognosis. Orchidectomy, when unilateral, can be carried out to increase the animal's productive life.


Author(s):  
Th. Shitarjit Singh ◽  
Pranab Chandra Kalita ◽  
Om Prakash Choudhary ◽  
Arup Kalita ◽  
Probal Jyoti Doley

The present study was designed to elucidate the histomorphology of the testis of adult Zovawk. In the present study, the collagen and reticular fibres were abundant in tunica albuginea and interstitial tissue surrounding the seminiferous tubules. However, few elastic fibers occurred in the capsule and only in the blood vessels of both the testis in Zovawk. The different micrometrical values with regard to thickness of testicular capsule, diameter of seminiferous tubule, height of seminiferous tubule, number of leydig cells, spermatogonia, germs cells per mm2 were found to be higher in the left testicle as compared to right one. There was no-significant difference observed in the right and left testes of Zovawk.


2005 ◽  
Vol 173 (4S) ◽  
pp. 254-254
Author(s):  
Raouf M. Seyam ◽  
Alaa Mokhtar ◽  
Walid Mourad ◽  
Raafat Alsayed ◽  
Kamal Hanash
Keyword(s):  

2014 ◽  
pp. 73-77
Author(s):  
Van Chuong Nguyen ◽  
Thi Kim Anh Nguyen

Background: A Research glomerular filtration rate (GFR) of 61 patients with type 2 diabetes mellitus with renal scanning 99mTc-DTPA glomerular filtration rate at the hospital 175. Objective: (1) To study characteristics of imaging of renal function. (2) Understanding the relationship between GFR with blood sugar, HbA1c, blood pressure and albuminuria in patients with type 2 diabetes. Methods: Descriptive, prospective, cross-sectional study. Clinical examination, Clinical tests and 99mTc-DTPA GFR gamma - camera renography for patients. Result: GFR of the study group was 75,4 ± 22,3 ml/phut/1,73m2, the left kidney was 35,0 ± 13,0 is lower than the right kidney and 39,8 ± 11,9; p <0,01. There is no correlation between GFR with blood glucose and HbA1c, the risk of reduced GFR in hypertensive group associated is OR = 6,5 with p<0,01; albuminuria (+) is OR = 4,2 with p <0,01; and disease duration > 10 years is OR = 3,5 with p <0.01. Conclusion: GFR of the left kidneys is lower than the right kidney; correlation decreased GFR associated with hypertension, albuminuria and disease duration. Keywords: GFR, diabetes, albuminuria


2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
M Swamad ◽  
M K Quraishi ◽  
S Ahmed

Abstract We present an interesting case of a 70-year-old female who presented with haematuria on the suspected cancer pathway. Renal ultrasound showed a vascular renal mass on her right kidney measuring 8x7cm with an unremarkable left kidney. She underwent a laparoscopic radical nephrectomy following confirmation of an 8cm renal mass in the right kidney on the contrasted staging CT scan with a repeat review at the multidisciplinary meeting. Post-operatively a subsequent review of the pre-operative CT and ultrasound scan, showed an incidental large left(contralateral) upper quadrant retroperitoneal fatty mass sized 15x10cm, displacing the stomach and spleen. Further investigation in the form of an MRI Abdomen excluded features of a liposarcoma, resulting in the diagnosis of a large retroperitoneal lipoma. This case highlights the significance of selective attention in imaging interpretation. We believe this to be a prime example of the level of meticulousness required as fat-rich tissues have low attenuation on CT-scans, which can be easily missed out. A cautious multi-clinician interpretation of scans should be performed to avoid missing potentially sinister pathology which would impact patient care dramatically. This case has led to more thorough review of future pre-operative imaging by the operating surgical team.


2018 ◽  
Vol 52 (6) ◽  
pp. 455-458
Author(s):  
Rogerio A. Muñoz-Vigna ◽  
Javier E. Anaya-Ayala ◽  
Juan N. Ramirez-Robles ◽  
Daniel Nuño-Diaz ◽  
Sandra Olivares-Cruz

The use of kidney grafts with aneurysmal disease involving the renal arteries for transplantation is very uncommon and relatively controversial. We herein present the case of a 52-year-old woman who volunteered to become a living-nonrelated donor; during the preoperative imaging workup, a computed tomography angiography revealed a 1.5-cm saccular aneurysm in the left kidney, while the contralateral renal artery was normal. We decided to utilize the left kidney for a 25-year-old male patient with end-stage renal disease, and following the ex vivo repair using the recipient epigastric vessels and saphenous veins, we completed the transplantation in the right pelvic fossa. The postoperative period was uneventful, and at 8 months from the surgery, the graft remains functional. The surgical repair of renal artery aneurysms followed by immediate kidney transplantation is a safe technique and an effective replacement therapy for recipients. The incidental finding of isolated aneurysmal disease in renal arteries should not exclude graft potential availability for transplantation following repair.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Satoshi Ieiri ◽  
Kouji Nagata

Abstract Background Pediatric hydronephrosis induced by pelvic-ureteric junction obstruction (PUJO) is treated by dismembered pyeloplasty (DP) via open and laparoscopic surgery. The etiology of PUJO involves both intrinsic stenosis and extrinsic compression of crossing vessels (CVs). PUJO owing to CVs is also treated by DP, as there is no consensus concerning this vascular condition. We encountered a 2-year-old infant with pure extrinsic PUJO combined with horseshoe kidney who successfully underwent laparoscopic transposition for CVs (vascular hitch). Case presentation A 2-year-old boy was prenatally diagnosed with left multicystic dysplastic kidney (MDCK) and right hydronephrosis and received a definitive diagnosis after birth. At 6 months old, renal scintigraphy revealed a non-functioning pattern in the left kidney and an obstructive pattern in the right, showing no response to furosemide loading. The patient also had recurrent urinary tract infection, and his right hydronephrosis gradually worsened. We decided to perform surgery for the right PUJO. Preoperative enhanced computed tomography detected three right renal vessels independently branching from the abdominal aorta. The middle renal vessels were located at the ventral side of the pelvis and coincident with the site of PUJO. These vessels were suspected of being CVs. The patient underwent laparoscopic surgery electively. A 5-mm trocar was inserted at the umbilicus for a 5-mm, 30° rigid scope. Two additional ports were then inserted under laparoscope inspection. The dilated right pelvis and CVs were detected after ascending colon mobilization. To confirm the pathogenesis of PUJO, the CVs were dissected and taped. After taping the CVs, an intraoperative diuretic test was performed using furosemide loading. Peristalsis of the right ureter was recognized, and the extrinsic PUJO owing to the CVs was definitively confirmed. We therefore performed transposition for the CVs (vascular hitch procedure). The CVs were mobilized in the cranial direction and those were wrapped by dilated pelvis. The post-operative course was uneventful. The renal scintigraphy findings improved and showed a favorable response of furosemide loading. Conclusions The laparoscopic vascular hitch procedure is minimally invasive and effective for extrinsic PUJO due to CVs. Anastomotic stricture after Anderson and Hynes DP can be prevented by appropriate patient selection.


2018 ◽  
Vol 7 (3) ◽  
pp. 107-112
Author(s):  
Bouzana Fatima ◽  
Sbahi Khayra ◽  
Kerroumi Slimane ◽  
Attar Abderahmane ◽  
Seghir Madjhouda Omar ◽  
...  

A stone is not only an obstacle, sometimes painful, on the urinary tract justifying an emergency urological gesture to restore their permeability. It is primarily a symptom of crystallogenic pathologies or urinary imbalances of nu-tritional origin whose recurrence is the rule if the cause has not been correctly identified. It is therefore recommended in the patient's interest; analyze the calcul or its fragments to determine its composition and structure, one and / or the other orienting towards the pathology in question. A series of 166 urinary stones were collected nearby the hospitals of western Algeria after urological intervention or spontaneous expulsion and sequential analysis of the nucleus at the surface by Fourier transform infrared spectrophotometry. The male / female ratio was 1.78. The study of the anatomical localization of the stones showed a predominance of the high urinary tract with a rate of 76.9%. 27.3% of the stones were located in the left kidney compared to 25.7% in the right kidney. Analysis of the crystalline composition showed that calcium oxalate was predominant in 65.8% of the calculs and in 58.5% of the nuclei. In all, whewellite was present in 46.9% of cases and weddellite in 18.9%. uric acid anhydrous was the major component of 12.2% of the calculations analyzed. It was present in 23.3% of cases with predominance in subjects over 60 years. Our results show that the lithiasis of the urinary tree in western Algeria tends to evolve in the same direction as that of the industri-alized countries.


PEDIATRICS ◽  
1949 ◽  
Vol 4 (2) ◽  
pp. 197-200
Author(s):  
LLOYD B. DICKEY ◽  
L. R. CHANDLER

A series of 12 cases of Wilms' tumor, in which the diagnosis was confirmed in all instances by examination of the gross or microscopic tissue, is reported, with a survival rate of 33.3%. Four patients are living and well, 4, 8, 10, and 15 years, respectively, after treatment. All recurrences appeared less than 10 months after treatment. The sex incidence, and the sex survival incidence were exactly equal. Six tumors were in the left kidney, and six in the right. Eight of the patients were under 2 years of age when first diagnosed and treated, and all were under 7 years. The history of breast or bottle feeding was irrelevant. In a large number of these and reported cases, the presence of the tumor was the first symptom, and in a considerable number the only symptom. This fact stresses the importance of careful physical examination of infants and young children, regardless of complaint, or of lack of it. The finding of calcification in the tumor is possibly a good prognostic sign. All three patients in whom calcification was noted in the tumor are living and well. Immediate removal of the tumor by transperitoneal nephrectomy, with postoperative radiation to the area, seems to be the advisable treatment.


1980 ◽  
Vol 239 (3) ◽  
pp. F265-F270 ◽  
Author(s):  
R. E. Colindres ◽  
W. S. Spielman ◽  
N. G. Moss ◽  
W. W. Harrington ◽  
C. W. Gottschalk

Acute left renal denervation in anesthetized volume-expanded rats produced an ipsilateral diuresis and natriuresis in 19 animals. A simultaneous decrease of glomerular filtration rate, p-aminohippurate clearance, urinary volume (P < 0.002), and percentage of filtered sodium excreted (4.0 +/- 0.6 (SE) vs. 1.9 +/- 0.4%, P < 0.003) occurred in the right innervated kidney in 10 rats. Prior denervation of the right kidney in the other nine rats prevented the renal hemodynamic changes and the fall of urinary volume and of sodium excretion (3.9 +/- 0.6 vs. 4.3 +/- 0.5%) by the right kidney after left renal denervation. Nerve traffic to the right kidney was measured in six other animals after left renal denervation and was found to increase to a mean value 33.8 +/- 6.3% above control levels (P < 0.007) 0-30 min after denervation, with a further significant increase to 66.2 +/- 16.1% above control levels (P < 0.025) 30-60 min after denervation. These results indicate that the functional changes in the right kidney after contralateral renal denervation in volume-expanded rats are caused by a reflex increase in nerve traffic to the right kidney, possibly as a consequence of an interruption of afferent nerve activity originating in the left kidney.


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