Seroprevalence of Hepatitis B and C Viruses among Blood Donors in Sulaimani Major Blood Bank for the Years 2006 and 2007: A Comparative Study

2008 ◽  
Vol 13 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Ali Hattem Hussein ◽  
Author(s):  
Anusha P ◽  
Bankar Nandkishor J ◽  
Karan Jain ◽  
Ramdas Brahmane ◽  
Dhrubha Hari Chandi

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.


2018 ◽  
Vol 25 (08) ◽  
pp. 1245-1251
Author(s):  
Mustansar Billah ◽  
Syed Muhammad Raza Shah ◽  
Muhammad Mujtaba Hashir

Objectives: To determine the frequency of HBV and HCV among blood donorscoming voluntarily at the blood bank of Ibne- Siena hospital and research centre, Multan,Pakistan, to ascertain the disease burden in the community for their future prevention andcontrol. Study Design: It was a descriptive, cross- sectional study on blood units donated byhealthy individuals coming voluntarily for blood donation, and willing to get their blood testedfor HBV, HCV. Setting: Community medicine department of Multan medical and dental collegeMultan, and blood bank of affiliated tertiary hospital, Ibn-e- Siena hospital Multan. Period: Sixmonths period from Jan 2016 to June 2016. Materials and Methods: Data of the blood donorswas collected. Present study was based on previous well maintained records of hospital bloodbank. During the reported period, a total of 1195 blood donors attended the blood bank, andthey all were screened for HBsAg and anti-HCV. SPSS- 16 was used to analyze the data, fordetermination of frequencies of Hepatitis- B, and C according to the age and gender. Results:Total numbers of blood donors were 1195. 1191 were males, and 4 were females. All thefemales were negative for both HBV, and HCV. Males positive for HBV were 18 (1.5 %), andthose Positive for HCV were 27 (3.2%).


2014 ◽  
Vol 1 (12) ◽  
pp. 1471-1479
Author(s):  
Prakash M Patil ◽  
Sneha Jawalkar ◽  
Shruti Kulkarni ◽  
Mayank Kumar ◽  
Shannawaz Mohd

2021 ◽  
Author(s):  
Tahira Shamim ◽  
Laila Sumreen

Abstract Hepatitis is commonly transmitted during blood transfusion. The study aimed to find the prevalence of hepatitis B & C among blood donors in Bahawalpur and try to find relation of prevalence with socio-demographic variables. The study was conducted in Bahawal Victoria Hospital Bahawalpur (BVH). The data was collected by trained nurses working in blood bank in supervision of investigator through a structured record review check list developed by investigator in English. The investigator checked data for completeness and cross check from registers. The collected data had been coded before analysis. Descriptive analysis was done to determine the prevalence of hepatitis B & C virus in the study population and its distribution categorized by independent variables i.e. age, gender, marital status, residence and education status of blood donor. The results of study indicated that both Hepatitis B & C are prevalent among 20 – 23 years old persons, males, uneducated people, married and people residing in rural areas of Bahawalpur visiting blood bank of Bahwal Victoria Hospital (BVH) Bahawalpur. So, by providing education to uneducated population and teaching sanitation and careful measures for avoiding hepatitis to married and people residing in rural areas could be a helpful tool in decreasing and controlling hepatitis in this area.


2021 ◽  
Vol 8 (14) ◽  
pp. 840-843
Author(s):  
Harjot Kaur ◽  
Parul Garg ◽  
Nirmaljot Kaur ◽  
Harmandeep Singh ◽  
Guneet Kaur Bakshi ◽  
...  

BACKGROUND Blood transfusion has been a boon to medical science, but at the same time, it exposes millions of people to transfusion transmitted infections (TTI). TTI are the infections that are transmissible from one person to another through parenteral administration of blood / blood products. Various TTIs are hepatitis C (HCV), hepatitis B (HBV), syphilis, human immunodeficiency viruses (HIV) and malaria. With increasing use of blood transfusion, chances of transmission of TTIs is very common but proper screening of donor blood has reduced the chances of TTI. The present study was done to know the seroprevalence of HCV, HBV, HIV and syphilis and their coinfections. METHODS A retrospective study was conducted by reviewing the records from January 2015 to December 2019 at a blood bank of Guru Ram Das Institute of Medical Sciences and Research at Amritsar, Punjab. Number of donors included in the study were 43,037. All the donors who came to blood bank were tested for TTIs by enhanced chemiluminescent immunoassay. METHODS A retrospective study was conducted by reviewing the records from January 2015 to December 2019 at a blood bank of Guru Ram Das Institute of Medical Sciences and Research at Amritsar, Punjab. Number of donors included in the study were 43,037. All the donors who came to blood bank were tested for TTIs by enhanced chemiluminescent immunoassay. RESULTS Number of donors tested for TTI was 43,037. Out of 43037, 1739 patients had serological evidence of TTIs, out of which 1669 (96.19 %) had mono-infection and 70 (4.04 %) had coinfections. HCV & HBV (28 / 70) was the most common combination, followed by HCV & HIV (20 / 70), HCV & syphilis (9 / 70), HIV & syphilis (5 / 70), HBV & syphilis (3 / 70) and HBV & HIV (1 / 70). Two donors had HIV, HCV & syphilis coinfections and two donors had HIV, HBV & HCV coinfections. CONCLUSIONS The present study documents the high prevalence of TTI out of which hepatitis C is the most common followed by hepatitis B. Among coinfections, two most prevalent coinfections are HCV & HBV and HCV & HIV and it is important to screen for these coinfections due to their impact on the course of disease as well as quality of life. This shows the increasing evidence of transfusion transmissible infection in blood donors in spite of advanced and vigilant screening of donated blood prior to transfusion. So, strategies should be devised for monitoring the implementation of post donation counselling for recruitment of safe donors. KEYWORDS Coinfections, Transfusion Transmitted Infections, Seroprevalence


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