scholarly journals Efeitos do exercício físico sobre a pressão e rigidez arterial em pacientes com diabetes mellitus tipo 2: revisão de literatura

2016 ◽  
Vol 14 ◽  
pp. 290
Author(s):  
Mirian Rebeca Alves Moura ◽  
Paula Taysa da Rocha Bezerra ◽  
Melyssa Lima de Medeiros ◽  
Rodrigo Marcel Valentim da Silva
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Arterial Stiffness ◽  
Physical Exercise ◽  
Arterial Pressure ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type

Introduction: Diabetes mellitus type 2 increases the mortality and the risk of premature morbidity related to cardiovascular disease. High blood pressure stands out as the main morbidity in this diabetic patient and arterial stiffness by one of the common complications associated with the disease, both of which can precipitate the occurrence of vascular disorders. In this context, the physical exercise is considered an important component in the treatment of these patients, as it helps in the control of cardiovascular risk factors. Objective: To investigate the effects of the physical exercise on pressure and arterial stiffness in patients with type 2 Diabetes mellitus. Methods: This is a literature review conducted in the period March-April 2015 in MEDLINE, LILACS, SciELO, PubMed and Cochrane databases. The keywords used were "Type 2 Diabetes Mellitus", "Exercise", "Arterial Stiffness" and "Arterial Pressure", combined by the boolean operator "and" being considered for this review only studies published between 2009 and 2015. Results: A total of 146 publications, were select 8 studies that investigated the effects of physical exercise on blood pressure and arterial stiffness in patients with type 2 Diabetes mellitus. Of these, 6 studies investigated the effects of physical exercise on blood pressure, which was completed in 4 of them, that it was effective in promoting protective effects of blood pressure. With respect to arterial stiffness, analyzed in four studies, it was found that aerobic training was able to generate reductions in their values after 3 months of intervention, which however were not maintained after longer periods. Conclusion: The physical exercise can be appointed as a promising strategy for arterial pressure control in patients with diabetes mellitus type 2. With regard to arterial stiffness, it is assumed that structural vascular changes manifested in the disease process present irreversible characteristics and therefore can not be modified even after long periods of intervention.

scholarly journals A prospective and observational study on complications of type 2 diabetes mellitus in correlation with body mass index

2019 ◽  
Vol 7 (12) ◽  
pp. 4723
Author(s):  
R. Siddarama ◽  
G. Thrinath ◽  
J. Bhagyasree ◽  
S. Afshaan Anjum ◽  
R. Anjanamma
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Observational Study ◽  
Diabetic Complications ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type ◽  
Macrovascular Complications ◽  
Complications Of Diabetes

Background: The aim of this study is to observe the prevalence of complications of diabetes mellitus (Type 2) among patients and to minimize their occurrence through patient education. The study helps to assess the clinical data of patients with diabetes mellitus (Type 2) along with the analysis of patterns, frequencies and predictive factors of microvascular, macrovascular complications and to educate and minimize the complications of diabetes mellitus among patients.Methods: Prospective and observational study was conducted among the type 2 diabetes mellitus patients at Sree Diabetes Clinic for a period of 6 months. The patients were interviewed using the patient data collection form which included demographic details, chief complaints and different diagnostic tools to detect type of complications. Both micro and macrovascular complications were evaluated.Results: A total of 150 type 2 diabetic cases were collected. Out of these 38(25.33%) patients were having BMI <25, and 112(74.67%) were having BMI ≥25 (overweight and obese). Out of 150 diabetic cases collected, a total of 131 diabetic complications were found. Out of these, 64(42.6%) were neuropathy, 3(2%) were nephropathy, 20(13.3%) were retinopathy and 17(11.3%) were having cardiovascular complications. Out of 112 patients with BMI ≥25, 60(54%) were found to have diabetic complications and out of 38 patients with BMI <25, 18(47%) were found to have diabetic complications. 90 out of 150 patients had a history of hypertension and 17 out of 150 patients had an abnormal lipid level.Conclusions: In this study, author found that obesity is a major risk factor for the development of diabetes mellitus and its complications.

scholarly journals ASSOCIATION OF TYPE 2 DIABETES MELLITUS WITH ABO AND RH BLOOD GROUP

2021 ◽  
Vol 71 (5) ◽  
pp. 1848-51
Author(s):  
Asma Tasneem ◽  
Samina Naeem ◽  
Nasir Uddin ◽  
Maria Farid ◽  
Shehneela Jabeen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Group ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type ◽  
Control Group ◽  
Group B ◽  
Rh Blood Group

Objective: To find out the association of type 2 diabetes mellitus with ABO and Rh blood groups. Study Design: Cross sectional study. Place and Duration of Study: Department of Haematology, Combined Military Hospital Lahore, from Jul to Dec 2020. Methodology: A total 179 patients with type 2 diabetes mellitus and 50 healthy individuals were inducted into the study. Five (5ml) blood from the patients was taken via clean aseptic venipuncture in a tube containing EDTA. HbA1C was generated through automated analyzer Cobas c501 and blood grouping was carried out using tube method by an experienced technician. Results: A total of 179 (77.8%) individuals with diabetes mellitus type 2 and 50 (21.7%) healthy cases were inducted into the study as a control group. A statistically significant difference was observed with blood group B being the most prevalent among them (p=0.001). There was a greater frequency of Rh-negative blood group in patients having diabetes mellitus type 2 as compared to the control group. Conclusion: There is a strong association found between ABO and Rh blood group with diabetes mellitus type 2. Blood group B negative was the most common among the patients having diabetes mellitus type 2. Blood group O positive showed the least association.

scholarly journals Effectiveness of Chrono-Pharmacotherapy Depending on the Salt Sensitivity of Patients with Arterial Hypertension and Diabetes Mellitus Type 2

2019 ◽  
Vol 14 (6) ◽  
pp. 846-851
Author(s):  
V. V. Skibitskiy ◽  
A. A. Kiselev ◽  
A. V. Fendrikova
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Arterial Stiffness ◽  
Diabetes Mellitus Type 2 ◽  
Blood Pressure Monitoring ◽  
Aortic Pressure ◽  
Diabetes Mellitus Type ◽  
Pressure Monitoring ◽  
Central Aortic Pressure

Aim. To study the effect of two regimens of combined antihypertensive therapy during the day on daily monitoring of arterial pressure, central aortic pressure, and arterial stiffness, depending on the salt sensitivity of hypertensive patients with diabetes mellitus type 2. Material and methods. 130 hypertensive patients with type 2 diabetes mellitus were included into the study. They were divided into 2 subgroups: salt-sensitive (group 1) and salt-resistant (group 2), and then randomized to subgroups A and B of ongoing therapy: in the morning ramipril and indapamide retard, bedtime – amlodipine (subgroup 1A and 2A); or in the morning amlodipine and indapamide retard, bedtime – ramipril (subgroup 1B and 2B). Initially and after 24 weeks of antihypertensive therapy, 24-hour blood pressure monitoring was performed, the indices of central aortic pressure and arterial stiffness were determined. Results. After 24 weeks, in all subgroups, there was a significant positive dynamics of the parameters of 24-hour blood pressure monitoring, central aortic pressure and arterial stiffness indices. In the subgroup 1В, it was registered a significant improvement in the majority of parameters of 24-hour blood pressure monitoring (decrease in 24-hours systolic BP by 24.4%, 24-hours diastolic BP by 22.1%; p<0.05), central aortic pressure (decrease in aortal systolic BP by 15.9%, aortal diastolic BP by 20.8%; p<0.05) and vascular wall stiffness parameters (decrease in pulse wave velocity by 13.8%; p<0.05) in comparison with group 1A (decrease in 24-hours systolic BP by 17.5%, 24-hours diastolic BP by 14.6%, aortal systolic BP by 12.7%, aortal diastolic BP by 9.7%, pulse wave velocity by 9.2%; p<0.05 in comparison with the group 1B). In the case of salt-resistant patients, there were comparable positive changes in the parameters of 24-hour blood pressure monitoring, central aortic pressure and arterial stiffness indices against the background of both dosing regimens during the day. Conclusion. In the study, it was demonstrated the more pronounced antihypertensive and vasoprotective efficacy of the combination of thiazide-like diuretic with calcium channel blocker in the morning and ACE inhibitor in bedtime compared to the alternative regimen of prescribed pharmacotherapy in salt-sensitive patients, and comparable efficacy of both regimens in salt-resistant hypertensive patients with diabetes mellitus type 2.

Papéis ocupacionais e diabetes tipo 2 / Occupational Roles and Diabetes Mellitus Type 2

2020 ◽  
Vol 4 (5) ◽  
pp. 785-799
Author(s):  
Beatriz Silva de Magalhães ◽  
Juliana Valéria De Melo ◽  
Fernanda De Sousa Marinho ◽  
Claúdia Regina Lopes Cardoso ◽  
Gil Fernando Da Costa Mendes de Salles
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Occupational Therapy ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type ◽  
Occupational Roles ◽  
The Impact ◽  
Diabetes Tipo 2

O Diabetes Mellitus tipo 2 (DM2), o tipo mais prevalente na população, pode interferir em hábitos e rotinas presentes na vida de um sujeito e consequentemente pode acarretar mudanças nos papéis ocupacionais. Avaliar e intervir nos papéis ocupacionais dos indivíduos é parte do domínio da Terapia Ocupacional. Objetivo: Analisar a produção acadêmica sobre o impacto nos papéis ocupacionais de pessoas com Diabetes Mellitus tipo 2. Metodologia: Trata-se de uma revisão bibliográfica integrativa da literatura, realizada na base de dados PUBMED. Foram criadas três categorias para análise: Entendendo o contexto do paciente com Diabetes Tipo 2; Diabetes Mellitus Tipo 2 e Papéis Ocupacionais; e Rede de suporte. Resultados: Selecionaram-se nove artigos para análise e, desses, um foi relacionado ao processo terapêutico ocupacional. Os demais referiam-se ao impacto nos papéis ocupacionais de maneira indireta. Não foram encontrados estudos que utilizassem a Lista de Identificação de Papéis Ocupacionais para verificar quais destes foram modificados após o diagnóstico. Discussão: Percebeu-se que o contexto do indivíduo com DM2 após o diagnóstico sofre mudanças que impactam nos hábitos e na rotina. Os papéis ocupacionais identificados foram: de maneira direta, Membro da Família e Trabalhador; e de forma indireta, Cuidador e Amigo. Considerações finais: Os papéis ocupacionais podem ser alterados em indivíduos com DM2. Nessa direção, espera-se que essa revisão motive novos estudos que façam uso da Lista de Identificação de Papéis Ocupacionais junto a indivíduos com DM2, para abordar de forma direta essa temática. AbstractDiabetes mellitus type 2 (DM2), the most prevalent type in the population, can interfere with habits and routines present in the life of a subject and consequently can lead to changes in the occupational roles. Assessing and intervening in the occupational roles of individuals is part of the field of Occupational Therapy. Objective: To analyze the academic production on the impact on the occupational roles of people with Type 2 Diabetes Mellitus. Methodology: This work is an integrative bibliographical review of the literature, carried out in the PUBMED database. Three categories were established for analysis: Understanding the context of the patient with Type 2 Diabetes; Type 2 Diabetes Mellitus and Occupational Roles; and Network Support. Results: Nine articles were selected for analysis, of which one was related to the occupational therapeutic process. The others referred to the impact on occupational roles indirectly. No studies were found that used the Role Checklist to verify which roles were modified after diagnosis. Discussion: It was noticed that the context of the individual with DM2 after the diagnosis undergoes changes that impact the habits and routine. The occupational roles identified were: directly, Family Member and Worker; and indirectly, Caregiver and Friend. Conclusion: The occupational roles can be altered in individuals with DM2. In this direction, it is expected that this review will motivate new studies that make use of the Role Checklist with individuals with DM2 to approach this issue in a direct way.Keywords: Role Performance; Diabetes Mellitus Type 2; Role Checklist; Occupational Roles; Occupational Therapy. ResumenLa Diabetes Mellitus tipo 2 (DM2), el tipo más prevalente en la población, puede interferir en hábitos y rutinas presentes en la vida de un sujeto y consecuentemente puede acarrear cambios en los papeles ocupacionales. Evaluar e intervenir en los papeles ocupacionales de los individuos es parte del dominio de la Terapia Ocupacional. Objetivo: Analizar la producción académica sobre el impacto en los papeles ocupacionales de personas con Diabetes Mellitus tipo 2. Metodología: Se trata de una revisión bibliográfica integrativa de la literatura, realizada en la base de datos PUBMED. Se crearon tres categorías para el análisis: Entendiendo el contexto del paciente con Diabetes Tipo 2; Diabetes Mellitus Tipo 2 y Papeles Ocupacionales; y Red de soporte. Resultados: Se seleccionaron nueve artículos para análisis y, de éstos, uno fue relacionado al proceso terapéutico ocupacional. Los demás se refirieron al impacto en los papeles ocupacionales de manera indirecta. No se encontraron estudios que utilizaran la Lista de Identificación de Papeles Ocupacionales para verificar cuáles de éstos fueron modificados después del diagnóstico. Discusión: Se percibió que el contexto del individuo con DM2 después del diagnóstico sufre cambios que impactan en los hábitos y en la rutina. Los papeles ocupacionales identificados fueron: directamente, Miembro de la Familia y Trabajador; y indirectamente, Cuidador y Amigo. Consideraciones finales: Los papeles ocupacionales pueden ser alterados en individuos con DM2. En esta dirección, se espera que esta revisión motive nuevos estudios que hagan uso de la Lista de Identificación de Papeles Ocupacionales junto a individuos con DM2, para abordar de forma directa esa temática.Palabras clave: Rendimiento de Papeles; Diabetes Mellitus tipo 2; Lista de identificación de papeles ocupacionales; Papeles ocupacionales; Terapia ocupacional. 

scholarly journals Prevalence of Type 2 Diabetes Mellitus among People Attending Medical Camp in a Community Hospital

2020 ◽  
Vol 58 (225) ◽  
Author(s):  
Anu Kushwaha ◽  
Anuj Raj Kadel
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Diabetes Mellitus Type 2 ◽  
Blood Sugar Level ◽  
Community Hospital ◽  
Diabetes Mellitus Type ◽  
Random Blood Sugar

Introduction: Diabetes is a health problem on the rise in developing countries like Nepal. Oftenin the suburban and rural areas, patients are diagnosed in the late stages with complications. Theaim of this study is to find out the prevalence of diabetes type 2 in a community hospital of Nepal. Methods: This is a descriptive cross-sectional study done in a community hospital from January toMarch of 2019 after ethical clearance (Registration number: 150320192) from the institutional reviewcommittee of Kathmandu Medical College. Convenient sampling technique was used. Glucometerusing glucose sticks is used to measure random blood sugar level and relevant questions were askedin a short interview. The data were analyzed using the Statistical Package for the Social Sciences 20version. Results: Out of a total of 114 people, the prevalence of type 2 diabetes mellitus was 5 (4.38%). Amongthose 5 (4.385%) people with type 2 diabetes mellitus, 2 (1.75%) were female and 3 (2.63%) were male.The minimum age of the patient was 17 years and the maximum age was 92 years. Five out of 95patients with mild physical activity had random blood sugar more than 200 mg/dl and five out of46 alcoholic patients had random blood sugar levels more than 200 mg/dl. Only 1 out of 26 smokershad a random blood sugar level of more than 200 mg/dl. Conclusions: Prevalence of diabetes mellitus type 2 in our study population is quite high. Earlydetection of diabetes mellitus type 2 can be a good screening tool for early treatment and preventionof complications.  

KADAR KALSIFEDIOL SEBAGAI PREDIKTOR DERAJAT KEPARAHAN RETINOPATI DIABETIK PADA PASIEN DENGAN DIABETES MELLITUS TIPE 2

2021 ◽  
Vol 8 (3) ◽  
pp. 211-224
Author(s):  
Gilbert Sterling Octavius ◽  
Alvita Suci Edgina ◽  
Stefany Tanto ◽  
Werlison Tobing
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Diabetes Mellitus Type 2 ◽  
Case Control ◽  
Diabetes Mellitus Type ◽  
Cross Sectional ◽  
Prevalence Of Diabetes Mellitus

Pendahuluan    : Terdapat peningkatan prevalensi pasien diabetes mellitus (DM) dan morbiditasnya, termasuk retinopati diabetik. Retinopati diabetik adalah penyebab paling sering dari kasus baru kebutaan di antara orang dewasa berusia 20-74 tahun yang akan mempengaruhi produktivitas kelompok usia ini jika dibiarkan atau tidak diobati. Tujuan : Mengevaluasi kemungkinan tingkat kalsifediol sebagai prediktor keparahan retinopati diabetik pada pasien dengan diabetes mellitus tipe 2. Metode : Kami mencari di PubMed, Kemajuan Oftalmologi, Laporan Ilmiah dan Ilmu Pengetahuan Langsung menggunakan istilah “25(OH)D3 Level”, “Diabetic Retinopathy”, “Prevalence of Diabetes Mellitus”, “Type 2 Diabetes Mellitus”, dan “Predictor” dalam berbagai kombinasi dan menemukan 7 studi yang digunakan dalam ulasan ini. Hasil                : Kami menemukan 4 literatur yang menyatakan bahwa ada hubungan positif antara level 25 (OH) D3 sebagai prediktor untuk keparahan retinopati diabetik sementara ada 3 literatur yang menyatakan sebaliknya. Enam literatur menggunakan desain cross sectional sedangkan satu dilakukan dengan menggunakan case control. Tingkat pemotongan 25(OH)D3 pada pasien dengan masing-masing 18,9-24,3 ng/ml, 17,4-21,7 ng/ml, dan 14,7-21,1 ng/ml. Kesimpulan      : Sementara penggunaan 25(OH)D3 sebagai prediktor tingkat keparahan retinopati diabetik masih tidak meyakinkan, hubungan proporsional terbalik terlihat antara kedua variabel.

SO036THE EFFECT OF DAPAGLIFLOZIN ON AMBULATORY AORTIC BLOOD PRESSURE AND ARTERIAL STIFFNESS PARAMETERS IN PATIENTS WITH TYPE-2 DIABETES MELLITUS: A DOUBLE-BLIND RANDOMIZED CLINICAL TRIAL

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Eirini Papadopoulou ◽  
Charalampos Loutradis ◽  
Kalliopi Kotsa ◽  
Spiros Karras ◽  
Christos Sambanis ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Clinical Trial ◽  
Type 2 Diabetes Mellitus ◽  
Arterial Stiffness ◽  
Double Blind ◽  
Type 2 Dm

Abstract Background and Aims Arterial stiffness is a prominent risk factor for heart failure and overall mortality in patients with type-2 diabetes mellitus (DM). Sodium-glucose co-transporter 2 (SGLT-2) inhibitors reduce the incidence of heart failure and death in these patients. The aim of this study is to evaluate the effects of dapagliflozin on ambulatory central blood pressure (BP) levels and arterial stiffness parameters in patients with type-2 DM. Method This is a double-blind, randomized, placebo-controlled clinical trial including 85 adult patients with type-2 DM on monotherapy or combination therapy with two of: metformin, sulphonylurea, DDP-4 inhibitor, or insulin. Patients were randomized in a 1:1 ratio to oral dapagliflozin 10 mg per day or placebo for 12 weeks. Study participants underwent 24-h ambulatory BP monitoring with the Mobil-O-Graph NG monitor at baseline and study-end. Results Baseline demographic, clinical and laboratory parameters were similar in the two groups (age 61.74±6.73 vs 60.64±9.35; p=0.534). During follow-up, 24-hour central SBP/DBP significantly decreased in dapagliflozin (117.41±10.52/78.88±7.25 vs 113.30±8.75/77.25±6.54; p=0.002/p=0.047), but not in the placebo group. Corresponding reductions of 24-hour central SBP (-4.12±8.00 vs -0.65±7.77; p=0.046) were greater with dapagliflozin than placebo. Aortic pulse pressure (PP) decreased only in the dapagliflozin group (38.53±7.44 vs 36.05±6.59 mmHg; p=0.004). 24-hour heart-rate adjusted augmentation-index significantly decreased with dapagliflozin. Importantly, there was a significant difference in the change of 24-hour PWV (-0.16±0.32 vs 0.02±0.27; p=0.007) favoring dapagliflozin. Conclusion Treatment with dapagliflozin significantly reduces ambulatory central BP and PWV levels in type-2 diabetics. Improvement in these parameters may substantially contribute to the cardiovascular benefits of SGLT-2 inhibitors.

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