Cholesterol and blood pressure

1930 ◽  
Vol 26 (12) ◽  
pp. 1248-1248
Author(s):  
N. Kramov

Abstracts. Internal illnesses. Cholesterol and blood pressure. Westphal found 71% of high blood pressure cases with elevated blood cholesterol. Askenazy found the same thing. Thomas, injecting cholesterol into rabbits, observed an increase in blood pressure.

2008 ◽  
Vol 101 (6) ◽  
pp. 776-786 ◽  
Author(s):  
Esther Boelsma ◽  
Joris Kloek

Hypertension or high blood pressure is a significant health problem worldwide. Typically, lifestyle changes, including adopting a healthy diet, are recommended for people with an elevated blood pressure. Lactotripeptides are bioactive milk peptides with potential antihypertensive properties in man. These peptides, as part of a food product or as nutraceutical, may contribute to the prevention and treatment of hypertension. This paper reviews the current evidence of the blood pressure control properties of lactotripeptides in man. Blood pressure-lowering effects of lactotripeptides are typically measured after 4–6 weeks of treatment. However, in some cases, a blood pressure response has been observed after 1–2 weeks. Maximum blood pressure reductions approximate 13 mmHg (systolic blood pressure) and 8 mmHg (diastolic blood pressure) after active treatment compared with placebo, and are likely reached after 8–12 weeks of treatment. Effective dosages of lactotripeptides range from 3·07 to 52·5 mg/d. Evidence indicates that lactotripeptides are only effective at elevated blood pressure; no further lowering of normal blood pressure has been observed. Concomitant intake of antihypertensive medication does not seem to influence the potency of lactotripeptides to lower blood pressure. Similarly, ethnicity has not been found to influence the extent of lactotripeptide-induced blood pressure lowering. Based on the currently available data, lactotripeptides appear to be safe and effective. Thus, they can be part of a healthy diet and lifestyle to prevent or reduce high blood pressure.


2009 ◽  
Vol 54 (S1) ◽  
pp. 94-99 ◽  
Author(s):  
Amy Z. Fan ◽  
Tara W. Strine ◽  
Shravani Reddy Muppidi ◽  
Kurt J. Greenlund ◽  
Janet B. Croft ◽  
...  

Author(s):  
NIKITHA G ◽  
RAJENDRA SANDUR V

Cardiovascular diseases (CVDs) are a class of diseases involving heart or blood vessels. Coronary artery diseases include angina, myocardial infarction (MI), stroke, heart failure, hypertensive heart disease, cardiomyopathy, and arrhythmias. CVDs are the leading cause of death globally. Risk factors include high blood pressure, smoking, obesity, poor diet, blood cholesterol, and lack of exercise. It is approximated that 90% of CVDs is preventable. High blood pressure results in 13% of CVD deaths, whereas tobacco outcomes in 9%, diabetes and lack of exercise in around 6%, and obesity in 5%. Due to certain medications such as anticancer drugs like doxorubicin, adverse effects result in MI. Since ancient times, medicinal plants have been widely used in the treatment of diseases. This information may serve as a primer in identifying novel prophylactic as well as therapeutic studies of plant-derived principles. The parts of the plants such as seeds, leaves, flowers, roots, and bark contain these phytoconstituents which are obtained through different extraction processes. Phytoconstituents are broadly classified into alkaloids, saponins, polyphenols, essential oils, carotenoids, glycosides, omega fatty acids, and flavonoids. Each class is responsible for its own pharmacological effects. The underlying mechanism in which they exert the action is different. This review presents an overview of the MI and therapeutic strategies of plant-derived principles that are available to mitigate the effect of MI.


2018 ◽  
Vol 7 (3.3) ◽  
pp. 114 ◽  
Author(s):  
Satyanarayana Nimmala ◽  
Y Ramadevi ◽  
B Ashwin Kumar

Every tissue of human body needs energy and oxygen for its livelihood. In order to supply energy and oxygen, the heart pumps the blood around the body. When heart pushes the blood against the walls of arteries, it creates some pressure inside the arteries, called as blood pressure. If this pressure is more than the certain level we treat it as high blood pressure (HBP). Nowadays HBP is a silent killer of many across the globe. So here we proposed a new data-driven computational model to predict HBP. Blood Pressure (BP) may be elevated because of many changes such as physical and emotional. In the proposed model we have considered AAA++ (age, anger level, anxiety level, obesity (+), blood cholesterol (+)), for experimental analysis. Our model initially calculates the correlation coefficient (CC) between each risk factor and class label attribute. Then based on the impact of each risk factor value and CC, it assigns the corresponding weight to it. Then proposed model uses risk factor value and its weight to predict whether person becomes a victim of HBP or not. We have used real-time data set for experimental analysis. It consists of 1000 records, which are collected from Doctor C, a Medical Diagnostic center, Hyderabad, India. 


Author(s):  
Monika Semwal

Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and significant swelling. Other symptoms may include weight gain, feeling tired, and foamy urine. Complications may include blood clots, infections, and high blood pressure. Causes include a number of kidney diseases such as focal segmental glomerulosclerosis, membranous nephropathy, and minimal change disease. It may also occur as a complication of diabetes or lupus. The underlying mechanism typically involves damage to the glomeruli of the kidney. Diagnosis is typically based on urine testing and sometimes a kidney biopsy. It differs from nephritic syndrome in that there are no red blood cells in the urine. Treatment is directed at the underlying cause. Other efforts include managing high blood pressure, high blood cholesterol, and infection risk. A low salt diet and limiting fluids is often recommended. About 5 per 100,000 people are affected per year. The usual underlying cause varies between children and adults.


Hypertension ◽  
2021 ◽  
Author(s):  
Bethany Barone Gibbs ◽  
Marie-France Hivert ◽  
Gerald J. Jerome ◽  
William E. Kraus ◽  
Sara K. Rosenkranz ◽  
...  

Current guidelines published by the American Heart Association and the American College of Cardiology broadly recommend lifestyle approaches to prevent and treat elevated blood pressure and cholesterol. For patients with mildly or moderately elevated blood pressure and blood cholesterol, lifestyle-only approaches are the first line of therapy. The purpose of this scientific statement is to: (1) highlight the mild-moderate–risk patient groups indicated for lifestyle-only treatment for elevated blood pressure or cholesterol; (2) describe recommendations, average effects, and additional considerations when prescribing lifestyle treatment with physical activity; and (3) provide guidance and resources for clinicians to assess, prescribe, counsel, and refer to support increased physical activity in their patients. An estimated 21% and 28% to 37% of US adults, respectively, have mild-moderate–risk blood pressure and cholesterol and should receive lifestyle-only as first-line treatment. Of the recommended lifestyle changes, increasing physical activity has extensive benefits, including improving both blood pressure and blood cholesterol, that are comparable, superior, or complementary to other healthy lifestyle changes. Physical activity assessment and prescription are an excellent lifestyle behavior treatment option for all patients, including for the large population of mild-moderate–risk patients with elevated blood pressure and blood cholesterol.


1976 ◽  
Vol 51 (s3) ◽  
pp. 695s-696s
Author(s):  
T. Thulin ◽  
R. W. Pero ◽  
C. Bryngelsson ◽  
F. Mitelman ◽  
Å. Nordén ◽  
...  

1. The level of DNA repair synthesis has been compared in males diagnosed as having hypertension (diastolic blood pressure ≥ 100 mmHg), males with slightly elevated blood pressure (>95th percentile corrected for age) and males with normal or subnormal blood pressure (≤30th percentile corrected for age). 2. The hypertensive males and the males with elevated blood pressure could not be distinguished from each other with respect to the levels of chemically induced repair synthesis, but both were significantly increased over the induced repair synthesis values of individuals with normal or low blood pressure. Since it has been shown previously that lymphocytes with high repair synthesis values also have increased levels of both carcinogen-DNA binding and chromosomal aberrations (Nordén, Scherstén, Thulin, Pero, Bryngelsson & Mitelman, 1975), the biological significance of this variable appears to be of value in discriminating between normal and high blood pressure groups.


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