scholarly journals CARDIOPROTECTIVE POTENTIAL OF PLANTS AND PLANT-DERIVED PRINCIPLES – A REVIEW

Author(s):  
NIKITHA G ◽  
RAJENDRA SANDUR V

Cardiovascular diseases (CVDs) are a class of diseases involving heart or blood vessels. Coronary artery diseases include angina, myocardial infarction (MI), stroke, heart failure, hypertensive heart disease, cardiomyopathy, and arrhythmias. CVDs are the leading cause of death globally. Risk factors include high blood pressure, smoking, obesity, poor diet, blood cholesterol, and lack of exercise. It is approximated that 90% of CVDs is preventable. High blood pressure results in 13% of CVD deaths, whereas tobacco outcomes in 9%, diabetes and lack of exercise in around 6%, and obesity in 5%. Due to certain medications such as anticancer drugs like doxorubicin, adverse effects result in MI. Since ancient times, medicinal plants have been widely used in the treatment of diseases. This information may serve as a primer in identifying novel prophylactic as well as therapeutic studies of plant-derived principles. The parts of the plants such as seeds, leaves, flowers, roots, and bark contain these phytoconstituents which are obtained through different extraction processes. Phytoconstituents are broadly classified into alkaloids, saponins, polyphenols, essential oils, carotenoids, glycosides, omega fatty acids, and flavonoids. Each class is responsible for its own pharmacological effects. The underlying mechanism in which they exert the action is different. This review presents an overview of the MI and therapeutic strategies of plant-derived principles that are available to mitigate the effect of MI.

Author(s):  
Monika Semwal

Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and significant swelling. Other symptoms may include weight gain, feeling tired, and foamy urine. Complications may include blood clots, infections, and high blood pressure. Causes include a number of kidney diseases such as focal segmental glomerulosclerosis, membranous nephropathy, and minimal change disease. It may also occur as a complication of diabetes or lupus. The underlying mechanism typically involves damage to the glomeruli of the kidney. Diagnosis is typically based on urine testing and sometimes a kidney biopsy. It differs from nephritic syndrome in that there are no red blood cells in the urine. Treatment is directed at the underlying cause. Other efforts include managing high blood pressure, high blood cholesterol, and infection risk. A low salt diet and limiting fluids is often recommended. About 5 per 100,000 people are affected per year. The usual underlying cause varies between children and adults.


1930 ◽  
Vol 26 (12) ◽  
pp. 1248-1248
Author(s):  
N. Kramov

Abstracts. Internal illnesses. Cholesterol and blood pressure. Westphal found 71% of high blood pressure cases with elevated blood cholesterol. Askenazy found the same thing. Thomas, injecting cholesterol into rabbits, observed an increase in blood pressure.


2017 ◽  
Vol 2017 ◽  
pp. 1-8
Author(s):  
Zong-Bao He ◽  
You-Kui Lv ◽  
Hui Li ◽  
Qiong Yao ◽  
Ke-Ming Wang ◽  
...  

Atlantoaxial disorders are often correlated with hypertension in practice. In order to study the relationship between atlantoaxial disorder and hypertension, we attempted to construct an animal model. In this work, we presented an animal model where their atlantoaxial joints were misaligned. We investigated the changes of blood pressure before and after treatments of the modeled rats. We had the following results. (1) SBP and DBP of each surgery group were significantly higher than those of control and sham groups. (2) After the second operation (the fixture was removed), SBP and DBP of both surgery groups decreased and got closer to the control and sham groups after 7 days. (3) Heart rates got significantly higher in both surgery groups, compared to control and sham groups. (4) The blood Ach levels of the surgery groups were significantly lower than those of control and sham groups. With these results, we concluded that we successfully constructed cervical atlantoaxial disorder models in rats that showed hypertension symptom. However, the underlying mechanism connecting atlantoaxial disorder and hypertension still requires further study.


2009 ◽  
Vol 54 (S1) ◽  
pp. 94-99 ◽  
Author(s):  
Amy Z. Fan ◽  
Tara W. Strine ◽  
Shravani Reddy Muppidi ◽  
Kurt J. Greenlund ◽  
Janet B. Croft ◽  
...  

2018 ◽  
Vol 7 (3.3) ◽  
pp. 114 ◽  
Author(s):  
Satyanarayana Nimmala ◽  
Y Ramadevi ◽  
B Ashwin Kumar

Every tissue of human body needs energy and oxygen for its livelihood. In order to supply energy and oxygen, the heart pumps the blood around the body. When heart pushes the blood against the walls of arteries, it creates some pressure inside the arteries, called as blood pressure. If this pressure is more than the certain level we treat it as high blood pressure (HBP). Nowadays HBP is a silent killer of many across the globe. So here we proposed a new data-driven computational model to predict HBP. Blood Pressure (BP) may be elevated because of many changes such as physical and emotional. In the proposed model we have considered AAA++ (age, anger level, anxiety level, obesity (+), blood cholesterol (+)), for experimental analysis. Our model initially calculates the correlation coefficient (CC) between each risk factor and class label attribute. Then based on the impact of each risk factor value and CC, it assigns the corresponding weight to it. Then proposed model uses risk factor value and its weight to predict whether person becomes a victim of HBP or not. We have used real-time data set for experimental analysis. It consists of 1000 records, which are collected from Doctor C, a Medical Diagnostic center, Hyderabad, India. 


Author(s):  
A. N. Britov ◽  
M. I. Smirnova ◽  
V. M. Gorbunov ◽  
E. M. Platonova ◽  
N. A. Eliseeva ◽  
...  

2021 ◽  
Vol 4 (4) ◽  
pp. 832-837
Author(s):  
Wahid Tri Wahyudi ◽  
Yessi Aprianti ◽  
Dessy Hermawan

ABSTRAK Penyakit degeneratif merupakan penyakit jantung, hipertensi, diabetes, kegemukan dan lainnya. Salah satu penyakit degeneratif di antaranya hipertensi. Hipertensi adalah suatu penyakit darah tinggi merupakan suatu keadaan peredaran darah meningkat secara terus menerus dimana tekanan sistolik  lebih dari 140 mmHg, tekanan diastolik 90 mmHg. selain itu penyebab tekanan darah meningkat terjadi karena faktor usia, jenis kelamin, merokok, stress, kurang olahraga, genetic, alcohohol, konsentrasi garam dan obesitas.  Pengobatan non farmakologis untuk hipertensi yaitu terapi tertawa. Terapi tertawa adalah salah satu terapi untuk mencapai kegembiraan, kesenangan, kebahagiaan, didalam hati yang dikeluarkan melalui mulut dalam bentuk suara tawa, senyuman yang menghiasi wajah, suara hati yang lepas dan bergembira, peredaran darah yang lancar sehingga bisa mencegah penyakit. Adapaun kegiatan yang dilakukan berupa penyuluhan menggunakan leaflet dan SOP pemberian terapi tertawa. Terdapat penurunan Hipertensi setelah dilakukan terapi tertawa pada penderita Hipertensi di Desa Blambangan Umpu. Dengan demikian pemberian terapi tertawa sangat efektif dalam menurunkan Hipertensi. Kata Kunci: Hipertensi, Non Farmakologis, Terapi Tertawa  ABSTRACT Degenerative diseases are non-communicable diseases, which lasted chronic such as heart disease, hypertension, diabetes, obesity, and others. One of the degenerative diseases such as hypertension. Hypertension is a disease of high blood pressure is a state of increased blood circulation in which the systolic pressure is more than 140 mmHg, systolic pressure is 90 mmHg. besides that, the cause of increased blood pressure occurs due to factors of age, sex, smoking, stress, lack of exercise, genetic, alcohol, salt concentration, and obesity. Non-pharmacological treatment for hypertension is laughter therapy. Laughter therapy is a therapy to achieve joy, pleasure, happiness, in the heart that is issued through the mouth in the form of laughter, smiles that decorate the face, loose and happy conscience, and blood circulation that can be adapted to disease. As for the activities carried out in the form of counseling using leaflets and SOP providing laughter therapy. There was a decrease in hypertension after laughing was carried out in patients with hypertension in Blambangan Umpu village. The administration of laughter therapy is very effective in reducing hypertension Keywords: Hypertension, Non-Farmacology, Laughter Therapy


2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
Louis Z. G. Touyz

Liquorice has an active substance, Glycyrrhizin which inhibits the conversion of precursor cortisol to cortisone by inhibiting the enzyme11-betahydroxysteroid dehydrogenase. When imbibed, liquorice acts like hyperaldosteronism which presents with typical symptoms including high blood pressure, low blood potassium, and muscle pain and weakness. This article appraises physiological and pharmacological effects on health of liquorice, critiques products containing liquorice, describes a typical case report of liquorice-induced hypertension, and appraises oral effects from consumption of liquorice products.


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