scholarly journals Effect of kumis on the secretion of the pancreatic gland

2021 ◽  
Vol 32 (2-3) ◽  
pp. 134-140
Author(s):  
B. S. Maksudov
Keyword(s):  
Gastrointestinal Tract ◽  
Secretory Function ◽  
Pancreatic Gland ◽  
Number Of Authors

Kumis is a drink that energetically affects the activity of the gastrointestinal tract. A number of authors (Zarnitsyn, Grigorieva, Udintsev, Kandrashkin, Zorin, etc.) have established many details in the influence of kumis on the secretory function of the stomach.

Does Your Gut Taste? Sensory Transduction in the Gastrointestinal Tract

Physiology ◽  
1998 ◽  
Vol 13 (6) ◽  
pp. 275-280 ◽  
Author(s):  
Helen E. Raybould
Keyword(s):  
Gastrointestinal Tract ◽  
Absorptive Capacity ◽  
Endocrine Cells ◽  
Sensory Transduction ◽  
Regulatory Mechanisms ◽  
Neural Pathways ◽  
Secretory Function ◽  
Gastrointestinal Motor

The primary sensors in the gut are endocrine cells. They release peptides and amines that stimulate intrinsic and extrinsic neural pathways affecting gastrointestinal motor and secretory function. These regulatory mechanisms alter the digestive and absorptive capacity of the intestine to match the entry of a meal from the stomach.

scholarly journals A Multiphase Flow in the Antroduodenal Portion of the Gastrointestinal Tract: A Mathematical Model

2016 ◽  
Vol 2016 ◽  
pp. 1-18 ◽  
Author(s):  
P. V. Trusov ◽  
N. V. Zaitseva ◽  
M. R. Kamaltdinov
Keyword(s):  
Mathematical Model ◽  
Gastrointestinal Tract ◽  
Multiphase Flow ◽  
Human Body ◽  
Digestive System ◽  
System Model ◽  
Food Density ◽  
Secretory Function ◽  
Functional Disorders ◽  
Food Particles

A group of authors has developed a multilevel mathematical model that focuses on functional disorders in a human body associated with various chemical, physical, social, and other factors. At this point, the researchers have come up with structure, basic definitions and concepts of a mathematical model at the “macrolevel” that allow describing processes in a human body as a whole. Currently we are working at the “mesolevel” of organs and systems. Due to complexity of the tasks, this paper deals with only one meso-fragment of a digestive system model. It describes some aspects related to modeling multiphase flow in the antroduodenal portion of the gastrointestinal tract. Biochemical reactions, dissolution of food particles, and motor, secretory, and absorbing functions of the tract are taken into consideration. The paper outlines some results concerning influence of secretory function disorders on food dissolution rate and tract contents acidity. The effect which food density has on inflow of food masses from a stomach to a bowel is analyzed. We assume that the future development of the model will include digestive enzymes and related reactions of lipolysis, proteolysis, and carbohydrates breakdown.

scholarly journals Preclinical safety evaluation of drone brood homogenate and justification of pharmacological action

Pharmacia ◽  
2021 ◽  
Vol 68 (4) ◽  
pp. 771-777
Author(s):  
Bohdana Pavliuk ◽  
Iryna Stechyshyn ◽  
Mariana Chubka ◽  
Taras Hroshovyi
Keyword(s):  
Metabolic Syndrome ◽  
Gastrointestinal Tract ◽  
Gastric Mucosa ◽  
Large Scale ◽  
Toxic Substance ◽  
Active Pharmaceutical Ingredient ◽  
Pharmacological Action ◽  
Secretory Function ◽  
The Metabolic Syndrome ◽  
Drone Brood

The problem of studying the metabolic syndrome, as well as its integration into other pathological processes, despite large-scale research, remains relevant. The complexity of the interaction of different links in pathogenesis requires scientists to find new tools and methods for both diagnosis and treatment. Drone brood homogenate, which is a multifactorial pharmacological agent in terms of chemical composition, seems to be promising to study for today. And the lack of contraindications and a wide age range makes it an excellent object of research. The current study evaluated the pharmacological aspects of safety: acute toxicity, effects on the functional and motor activity of the gastrointestinal tract, as well as local irritation of the gastric mucosa, the secretory function of the stomach. All experiments were performed according to the classical methods. The specific pharmacological activity of the drone brood homogenate was determined in comparison with metformin in the experimental fructose metabolic syndrome. Animals obtained from the Vivarium of I.Horbachevsky Ternopil National Medical University were used to implement the set goals. Working with animals was met all bioethical requirements. The study found that the lyophilized drone brood homogenate does not have a local irritant effect and does not cause ulcers on the surface of the gastric mucosa, does not affect the secretory function of the stomach and motor-evacuatory activity of the gastrointestinal tract and is a low-toxic substance, indicating the possibility of its long-term safe use. As expected, glucose, insulin, and HOMA index were significantly increased in animals that were simulated metabolic syndrome. The use of drone brood homogenate by animals contributed to a relatively positive effect on selected indicators of the metabolic syndrome. Accordingly, drone brood homogenate is a promising active pharmaceutical ingredient for the normalization of biochemical disorders in metabolic syndrome.

scholarly journals CLINICAL AND ULTRASOUND PARALLELS IN DIAGNOSIS OF GASTROESOPHAGEAL REFLUX DISEASE AND AUTOIMMUNE THYROIDITIS

2020 ◽  
pp. 69-73
Author(s):  
Aleksey Oparin ◽  
Natalia Yarantseva ◽  
Anatoliy Oparin
Keyword(s):  
Gastrointestinal Tract ◽  
Thyroid Gland ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Thyroid Hormones ◽  
Reflux Disease ◽  
Ultrasound Examination ◽  
Clinical Course ◽  
Control Group ◽  
Secretory Function

The aim of the work: to study the relationship of ultrasound parameters of the thyroid gland with the clinical course, the level of thyroid hormones and indicators of the motor-secretory function of the gastrointestinal tract in patients with gastroesophageal reflux disease (GERD) and autoimmune thyroiditis (AIT). Materials and methods. The study involved three groups of patients. The first group consisted of 22 patients with isolated GERD. The second group included 20 patients suffering from GERD in combination with AIT in the hypothyroid stage. And the third group included 20 patients suffering from isolated AIT in the hypothyroid stage. The control group consisted of 15 apparently healthy individuals of the same age and sex. All patients underwent a comprehensive examination, which included the necessary set of clinical, laboratory and instrumental research methods in accordance with the local treatment protocols such as collection of complaints and anamnesis, patient examination, physical examination, clinical and biochemical analyzes, ECG, EGD, intragastric pH-metry. The patients underwent ultrasound examination of the motor-evacuation function of the esophagus and stomach with water load and an ultrasound examination of thyroid gland. The functional activity of thyroid gland was assessed by determining the level of thyroid hormones (TSH, T4 free, T3) by ELISA and the presence of antibodies to. Results. The study involved three groups of patients: patients with isolated gastroesophageal reflux disease, patients with a combined course of GERD and AIT in the hypothyroid stage and patients with isolated AIT in the hypothyroid stage. The most pronounced complaints, a higher level of thyroid-stimulating hormone and the most pronounced ultrasound changes are noted in patients with combined pathology. Ultrasound examination of the lower third of esophagus and stomach in patients of all three groups showed the presence of regurgitation, expansion of the lumen of the lower third of esophagus and an increase in the diameter of esophageal opening of diaphragm in varying degrees, in contrast to patients in the control group. Thus according to the results of thyroid sonography and ultrasound examination of the motor function of the lower third of esophagus and stomach, the most pronounced changes were found in the second group of patients who had a combined course of GERD and AIT. Conclusions. 1. A clear correlation was established between the clinical course, an increase in the level of thyroid hormones and ultrasound picture of thyroid gland and indicators of the motor-secretory function of the gastrointestinal tract in patients with GERD and AIT; It was shown that disorders in the activity of thyroid hormones affect the formation of motor-secretory disorders in patients with GERD with concomitant AIT which mutually aggravates the course of this comorbid pathology; Ultrasound diagnostics can be used as an evaluative method in this category of patients.

Habitat Association of Klebsiella Species

1985 ◽  
Vol 6 (2) ◽  
pp. 52-58 ◽  
Author(s):  
Susan T. Bagley
Keyword(s):  
Drinking Water ◽  
Gastrointestinal Tract ◽  
Surface Waters ◽  
Industrial Effluents ◽  
Opportunistic Pathogen ◽  
Habitat Associations ◽  
Habitat Association ◽  
Klebsiella Species ◽  
Almost All ◽  
Polluted Waters

AbstractThe genus Klebsiella is seemingly ubiquitous in terms of its habitat associations. Klebsiella is a common opportunistic pathogen for humans and other animals, as well as being resident or transient flora (particularly in the gastrointestinal tract). Other habitats include sewage, drinking water, soils, surface waters, industrial effluents, and vegetation. Until recently, almost all these Klebsiella have been identified as one species, ie, K. pneumoniae. However, phenotypic and genotypic studies have shown that “K. pneumoniae” actually consists of at least four species, all with distinct characteristics and habitats. General habitat associations of Klebsiella species are as follows: K. pneumoniae—humans, animals, sewage, and polluted waters and soils; K. oxytoca—frequent association with most habitats; K. terrigena— unpolluted surface waters and soils, drinking water, and vegetation; K. planticola—sewage, polluted surface waters, soils, and vegetation; and K. ozaenae/K. rhinoscleromatis—infrequently detected (primarily with humans).

The Interpretation of Solar Spectral Intensities

1988 ◽  
Vol 102 ◽  
pp. 329
Author(s):  
R.W.P. McWhirter
Keyword(s):  
Emission Measure ◽  
Physical Nature ◽  
Atomic Data ◽  
The Sun ◽  
Atomic Properties ◽  
Outer Atmosphere ◽  
Spectral Intensities ◽  
Thin Plasma ◽  
Number Of Authors

The intensity of a specrtal line from an optically thin plasma such as the outer atmosphere of the sun depends on both the atomic properties of the atomic ion responsible for the line and the physical nature of the plasma. In this paper we discuss the various ways in which the measured spectral intensities from the sun are used to discover something about the nature of the sun’s atmosphere. The technique has been referred to as the emission measure method. It has important limitations in terms of the accuracy of the specrtal data as well as the atomic data. We discuss some of these and suggest methods by which they may be assessed. The technique is illustrated by application to real observations from a number of authors.

Control of Secretory Production in the Isopod Hepatopancreas

1972 ◽  
Vol 30 ◽  
pp. 166-167
Author(s):  
John W. Roberts ◽  
E. R. Witkus
Keyword(s):  
B Cells ◽  
Morphological Data ◽  
Secretory Product ◽  
Secretory Function ◽  
Secretory Material ◽  
Blind Ending ◽  
Secretory Production ◽  
Regenerative Cells ◽  
Immature Cells ◽  
And Storage

The isopod hepatopancreas, as exemplified by Oniscus ascellus. is comprised of four blind-ending diverticula. The regenerative cells at the tip of each diverticula differentiate into either club-shaped B-cells, which serve a secretory function, or into conoid S-cells, which serve in the absorption and storage of nutrients.The glandular B-cells begin producing secretory material with the development of rough endoplasmic reticulum during their process of maturation from the undifferentiated regenerative cells. Cytochemical and morphological data indicate that the hepatopancreas sequentially produces two types of secretory material within the large club-shaped cells. The production of the carbohydrate-like secretory product in immature cells seems to be phased out as the production of the osmiophilic secretion was phased in as the cell matured.

The Effect of Androgen Depletion and Replacement on the Epithelium of the Seminal Vesicle of the Aging Rat

1975 ◽  
Vol 33 ◽  
pp. 590-591
Author(s):  
Venita F. Allison
Keyword(s):  
Cell Proliferation ◽  
Seminal Vesicle ◽  
Male Rats ◽  
Target Cells ◽  
Cell Regeneration ◽  
Secretory Function ◽  
Electron Microscopic ◽  
Aging Rat ◽  
Microscopic Studies ◽  
Androgen Depletion

In 1930, Moore, Hughes and Gallager reported that after castration seminal vesicle epithelial cell atrophy occurred and that cell regeneration could be achieved with daily injections of testis extract. Electron microscopic studies have confirmed those observations and have shown that testosterone injections restore the epithelium of the seminal vesicle in adult castrated male rats. Studies concerned with the metabolism of androgens point out that dihydrotestosterone stimulates cell proliferation and that other metabolites of testosterone probably influence secretory function in certain target cells.Although the influence of androgens on adult seminal vesicle epithelial cytology is well documented, little is known of the effect of androgen depletion and replacement on those cells in aging animals. The present study is concerned with the effect of castration and testosterone injection on the epithelium of the seminal vesicle of aging rats.

Casting with resins

1989 ◽  
Vol 4 ◽  
pp. 326-330
Author(s):  
J. Smith ◽  
B. Latimer
Keyword(s):  
Plaster Casting ◽  
Number Of Authors

Fossils are characteristically uncommon, making it impossible to distribute original specimens to all interested investigators. Dissemination of information, therefore, often depends upon the circulation of accurate reproductions. Such reproductions or casts can be made from a variety of materials including plasters and two-part resins. Using resins for the casting of paleontological specimens was discussed by a number of authors, including Burke and Jensen, 1961; Madsen, 1974; Parsons, 1973; Schrimper, 1973; Reser, 1981; and Burke et al., 1983 (see additional references in Hannibal, this volume, chapter 6). Plaster casting is covered by Babcock (this volume, chapter 34).

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