scholarly journals A Multiphase Flow in the Antroduodenal Portion of the Gastrointestinal Tract: A Mathematical Model

2016 ◽  
Vol 2016 ◽  
pp. 1-18 ◽  
Author(s):  
P. V. Trusov ◽  
N. V. Zaitseva ◽  
M. R. Kamaltdinov

A group of authors has developed a multilevel mathematical model that focuses on functional disorders in a human body associated with various chemical, physical, social, and other factors. At this point, the researchers have come up with structure, basic definitions and concepts of a mathematical model at the “macrolevel” that allow describing processes in a human body as a whole. Currently we are working at the “mesolevel” of organs and systems. Due to complexity of the tasks, this paper deals with only one meso-fragment of a digestive system model. It describes some aspects related to modeling multiphase flow in the antroduodenal portion of the gastrointestinal tract. Biochemical reactions, dissolution of food particles, and motor, secretory, and absorbing functions of the tract are taken into consideration. The paper outlines some results concerning influence of secretory function disorders on food dissolution rate and tract contents acidity. The effect which food density has on inflow of food masses from a stomach to a bowel is analyzed. We assume that the future development of the model will include digestive enzymes and related reactions of lipolysis, proteolysis, and carbohydrates breakdown.

2012 ◽  
Vol 17 (3) ◽  
pp. 56-59
Author(s):  
M. S. Grigorovich

The significance of the problem of acute intestinal infections (AII) to date is associated with both their prevalence and high rate of adverse effects in the outcome of the disease. In modern literature there is enough information about the frequent occurrence in AII patients microbiota disorders, immune system imbalances, identifying signs of reactive changes ofpancreatic tissue and functional disorders of biliary tract, lactase deficiency, long-term disorders of functional activity of the digestive system. The data about AII as one of the factors of forming the gastrointestinal tract pathology, including irritable bowel syndrome have been accumulated.


2020 ◽  
Vol 1 (1) ◽  
pp. 54-60
Author(s):  
Mahesh Prasad Sah ◽  
Bijendra Shah ◽  
Gouri Chauhan ◽  
OP Singh

Ayurveda defines human body is made of different gross and subtle channels called srotas. Srotas are the channels through which different elements undergo transformation, transmutation, circulation and transportation. The srotas is an integral part of the body, serving as a route to conduct or convey a substance from one place to other. There are 13 major srotas mentioned. The Srotas or channels which carry Anna or Food is called Annavaha Srotas. Some authorities equate the Annavaha Srotas with the some parts of digestive system or the gastrointestinal tract. Agni, the transformative energy, in the Annavaha srotas digest and transforms the food into components suitable for the body. Impairment of function of agni is root the cause of the disease, which manifest either in Annavaha srotas or other srotas in the body. Thus, correction of agni is the prime in treatment of any disease. Elimination of vitiated doshas by Pancakarma procedure viz Vaman and Virechana has shown to have impact on agni through various guna in the drugs used in these therapy. Sodhana procedures has a significant role in improving the function of agni and restoring the health.


2021 ◽  
pp. 93-104
Author(s):  
Yu. N. Panaseiko

Functional disorders of the digestive system (including gallbladder dyskinesia) are widespread among the adult population of the Russian Federation. Their combination in a fairly large percentage of cases with degenerative-dystrophic diseases of the spine, and the probable vertebrogenic causality of a number of the gastrointestinal tract pathological conditions lead to the need using new approaches in diagnosis and treatment, including non-drug methods. This clinical case shows the possibility of osteopathic diagnostics and correction in gallbladder dyskinesia.


2020 ◽  
Vol 21 (21) ◽  
pp. 8133
Author(s):  
Martin Marônek ◽  
René Link ◽  
Giovanni Monteleone ◽  
Roman Gardlík ◽  
Carmine Stolfi

The human virome, which is a collection of all the viruses that are present in the human body, is increasingly being recognized as an essential part of the human microbiota. The human gastrointestinal tract and related organs (e.g., liver, pancreas, and gallbladder)—composing the gastrointestinal (or digestive) system—contain a huge number of viral particles which contribute to maintaining tissue homeostasis and keeping our body healthy. However, perturbations of the virome steady-state may, both directly and indirectly, ignite/sustain oncogenic mechanisms contributing to the initiation of a dysplastic process and/or cancer progression. In this review, we summarize and discuss the available evidence on the association and role of viruses in the development of cancers of the digestive system.


Author(s):  
M. A. Khanday ◽  
Fida Hussain ◽  
Khalid Nazir

The development of cold injury takes place in the human subjects by means of crystallization of tissues in the exposed regions at severe cold temperatures. The process together with the evaluation of the passage of fluid discharge from the necrotic regions with respect to various degrees of frostbites has been carried out by using variational finite element technique. The model is based on the Pennes' bio-heat equation and mass diffusion equations together with suitable initial and boundary conditions. The results are analyzed in relation with atmospheric temperatures and other parameters of the tissue medium.


Author(s):  
Vrushali P. Kale Vrushali Purushottam Kale

According to Ayurveda, Jatharagni plays main role in the digestion process. Jatharagni carries its functions through Pachaka pitta. Grahani is an organ of gastrointestinal tract located between Amashaya and Pakwashaya, where digestion takes place. According to classical literature Pitta is same as Agni. Tridosha also plays very important role in the digestion process. In the recent days, irregular life style affects the digestive system and Jatharagni very badly. Whenever Agni gets (Vikrut) unbalanced due to wrong food habits and lifestyle, it should be understood that along with Agni, Pachaka Pitta will also get disturbed. Agnimandya is the root cause of most of the disorders like Grahani. Grahani organ is the main location of Jatharagni. Grahani is the organ where Pachak Pitta and Samanvayu carry out digestion. The most important function of Grahani is digestion of food with the help of Jatharagni, Pachakpitta, Pittadhara Kala and Samnvayu. Agni inside the body, digest the food give strength and maintain health. Samanvayu regulates the movements of the Grahani and helps in digestion. Hence, in this article we attempt to analyze and correlate patho-physiology of Grahani with respect to Physiological analysis of Agni and disturbed doshas. Etiological factors induces imbalance in Jatharagni, Pachak Pitta and Samanvayu and prolonged imbalance state weakens the Pittadhara Kala, which results in disease Grahani. Health of Grahani entirely depends on balanced state of Jatharagni, Pachaka Pitta, Pittadhara Kala and Samanvayu. The irregular life style, incompatible food habits creates Ama causes Grahani, affecting the digestive system and Jatharagni very badly.


Author(s):  
Aleksey Borisovich Petrukhin

Gastroenterology belongs to one of the leading branches of therapy. In the structure of diseases of the internal organs, diseases of the digestive system occupy a particularly important place due to their high prevalence, which increases with age. As a rule, these diseases have a chronic, progressive, recurrent course, which ultimately leads to severe disorders of the activity of many organs and systems of the body. The article presents the basic requirements for the formation of a clinical diagnosis of diseases of the gastrointestinal tract, which are most common in the practice of a family doctor.


Physiology ◽  
1998 ◽  
Vol 13 (6) ◽  
pp. 275-280 ◽  
Author(s):  
Helen E. Raybould

The primary sensors in the gut are endocrine cells. They release peptides and amines that stimulate intrinsic and extrinsic neural pathways affecting gastrointestinal motor and secretory function. These regulatory mechanisms alter the digestive and absorptive capacity of the intestine to match the entry of a meal from the stomach.


2002 ◽  
Vol 15 (3) ◽  
pp. 399-408
Author(s):  
Zoran Stajic ◽  
Dragan Petrovic ◽  
Dusan Arnautovic

The paper deals with significance of the starting generator (SG) driving torque modeling in the studies of synchronous starting of synchronous machines (SSSM). The detailed mathematical model of SSSM in reversible pumped storage plant (RPSP) "Bajina Basta" is derived. Because it is very difficult to include the detailed model of the SG turbine in the system model, function of SG driving torque is modeled approximately. The most frequent case in SSSM studies is its approximation with a time linear function, until it reaches the value that should provide rotating of both machine rotors with synchronous velocities, which is also used in the paper Afterwards, three different cases are considered: constant, linear and polynomial approximation in terms of SG rotor velocity. Numerical results obtained by applying developed models to a particular case of synchronous starting are compared with the corresponding experimental results. In this way, it is shown that the application of the most frequently used SG driving torque modeling leads to the erroneous results. The advantages of the polynomial approximation suggested in the paper and its validity is demonstrated.


Author(s):  
О. І. Мироненко

Вивчені особливості травлення у поросят післявідлучення, обґрунтовано використання окремих не-традиційних кормових добавок у раціонах поросят.Досліджено динаміку вмісту мінеральних елементів(кальцію, фосфору, калію, натрію, заліза) та їх обміну шлунково-кишковому тракті поросят під дієюокремих кормових добавок. Представлені результатидосліджень кормових добавок із сухого мінеральногоконцентрату, ліпроту та ехінацеї пурпурової з точкизору їх впливу на вміст у шлунку, порожній і клубовійкишках. The peculiarities of the digestive system in piglets after weaning, justified the use of certain non-conventional feed additives in the diets of pigs. The dynamics of the mineral elements (calcium, phosphorous, potassium, sodium, iron) and their metabolism in the gastrointestinal tract of pigs by the action of certain feed additives. The results of studies of dry feed additives mineral concentrate, Liprot and Echinacea purpurea in terms of their influence on the contents of the stomach empty and ileum.


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