scholarly journals Neurotrophic keratopathy and Wallenberg – Zakharchenko syndrome: a clinical case

2021 ◽  
Vol 14 (3) ◽  
pp. 83-90
Author(s):  
Maggie B. Ezugbaya ◽  
Sergey Y. Astakhov ◽  
Inna A. Riks ◽  
Sanasar S. Papanyan ◽  
Rafik Boutaba ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Trigeminal Nerve ◽  
Systemic Therapy ◽  
Neurological Disease ◽  
Clinical Case ◽  
Pathological Process ◽  
Rare Occurrence ◽  
Correct Treatment ◽  
Lack Of Information ◽  
Neurotrophic Keratopathy

BACKGROUND: Degenerative changes of cornea after transection of the trigeminal nerve were first described by F. Magendie in 1824. Neurotrophic keratopathy is considered to be an orphan disease which lately has been recognized more and more often. According to literature data, neurotropchic keratopathy affects 5 individuals in 10,000. The diagnosis is difficult due to the lack of information about this condition, the rare occurrence and the presence of a large number of etiological factors. AIM: To determine the causes of the neurotrophic keratopathy development and the treatment tactics in a patient with a neurological disease. The article presents a case of neurotrophic keratopathy in a patient with Wallenberg Zakharchenko syndrome. Because of the fact that neurotrophic keratopathy was diagnosed late and the correct treatment did not start in time, further progression of the pathological process in the cornea could not be avoided. Periodic recurrence of neurotrophic keratopathy is associated with an underlying chronic neurological disease. CONCLUSIONS: Neurotrophic keratopathy requires early diagnosis. In certain clinical cases, for the successful treatment of this pathology, it is necessary to prescribe systemic therapy.

Exérese de cementoblastoma benigno em região de sínfise mentoniana – relato de caso

2021 ◽  
Vol 12 (47) ◽  
pp. 55-59
Author(s):  
Sergio Bartolomeu de Farias Martorelli ◽  
Fernando de Oliveira Martorelli ◽  
Felipe Bravo Machado de Andrade ◽  
Allana Macêdo Montarroyos Dencker ◽  
Beatriz Gonçalves Rezende
Keyword(s):  
Young Adults ◽  
Female Patient ◽  
Local Anesthesia ◽  
Clinical Case ◽  
Pathological Process ◽  
Rare Occurrence ◽  
Mandibular Symphysis ◽  
Infectious Process ◽  
Condensing Osteitis ◽  
Children And Young Adults

Cementoma or cementoblastoma is a rare occurrence lesion, which can occur both in the mandible and in the maxilla. It affects children and young adults, with the area most affected by the premolars and molars. The diagnosis is differentiated with osteoblastoma, odontoma, condensing osteitis, cement-ossolifying fibroma, periapical cement dysplasia and hypercementosis. The histopathological aspect is of a mineralized mass similar to the cementum associated with a fibrovascularized stroma, interposed by cementoblasts. This article aimed to report a clinical case of symptomatic and infected benign cementoblastoma, located in the region of the mandibular symphysis in a 65-year-old female patient, whose treatment underwent excision under local anesthesia, with healing promoted by second intention due to the infectious process installed The treatment undertaken culminated in the cure of the pathological process.

scholarly journals Liver fibrosis in a child with open ductus venosus Arantii

2020 ◽  
pp. 130-133
Author(s):  
A. V. Nikitin ◽  
Т. A. Skvortsova ◽  
A. I. Khavkin ◽  
G. V. Volynets ◽  
A. О. Atameeva
Keyword(s):  
Portal Hypertension ◽  
Liver Fibrosis ◽  
Early Diagnosis ◽  
Biochemical Parameters ◽  
Clinical Case ◽  
Clinical Observation ◽  
Pathological Process ◽  
Ductus Venosus ◽  
Laboratory Parameters ◽  
Timely Treatment

The article presents a clinical case of liver fibrosis in a child on the background of open fetal vascular communication — ductus venosus Arantii. The clinical observation reflects the importance of early diagnosis, timely treatment of congenital pathology in children. It was shown that as a result of hepatoprotective therapy, the child showed a positive dynamics of clinical and laboratory parameters: a decrease in the severity of signs of portal hypertension, the size of the liver and spleen, a tendency to normalize biochemical parameters that reflect manifestations of the pathological process in the liver.

ENTRE ENCUENTRO Y DESENCUENTRO: TEMPORALIDAD EN TERAPIA DE PAREJA

2020 ◽  
Vol 1 (49) ◽  
pp. 69-89
Author(s):  
sofía De la Puerta ◽  
Carolina Correa
Keyword(s):  
Clinical Practice ◽  
Systemic Therapy ◽  
Couple Therapy ◽  
Clinical Case ◽  
Subjective Time ◽  
Present Moment ◽  
Clinical Process ◽  
Heterosexual Couple ◽  
Clinical Vignettes ◽  
One Year

The objective of this work is to understand a clinical process of systemic orientation from the perspective of subjective temporality. The work is based on the theory of subjective time and considers its historical and sociocultural dimension, reviewing its main theoretical constructs that will understand couple relationships and therapeutic processes. A clinical case was analyzed a from the perspective of subjective temporality, based on the main antecedents of the case and using clinical vignettes. Participants were a 36- and 37-year-old heterosexual couple who participated in a couple therapy with two therapists trained in systemic therapy for approximately one year. The sessions were videotaped and analyzed through the theory of subjective temporality. The analysis of the subjective temporality constitutes a contribution to the clinical practice, since it allows to understand and to develop an approach centered in the present moment and that allows analyzing the synchrony and encounter of the members of the system.

scholarly journals CASE OF OCULAR MANIFESTATIONS HYDROXYCHLOROQUINS TOXIC EFFECT

2011 ◽  
Vol 2 (2) ◽  
pp. 12-21 ◽  
Author(s):  
A A Kazaryan ◽  
E Nikolaevna Ponomareva
Keyword(s):  
American Academy ◽  
Clinical Case ◽  
Difficult Problem ◽  
Diabetes Type ◽  
Diabetes Type 1 ◽  
Effective Screening ◽  
Ocular Manifestations ◽  
Lack Of Information ◽  
Uncommon Disease

Based on experience and analysis of a few articles, devoted to this topic, the authors diagnose and describe the clinical case of the rare symptoms' group, associated with taking of hydroxychloroquine by the patient with sarcoidosis and diabetes type 1. The diagnostics of this lesion is difficult problem in the regular ophthalmologic practice, because of the uncommon disease, the lack of information and continuity between specialists, especially rheumatologists and pulmonologists. The recommendations of American Academy of Ophthalmology for effective screening of patients undergoing hydroxychloroquine therapy are given in this report.

scholarly journals Delayed Diagnosis of Unilateral Mandibular Condylar Fracture in a Posterior Edentulous Patient

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Sahani Anupama ◽  
Pilana Vithanage Kalani Shihanika Hettiarachchi
Keyword(s):  
Early Diagnosis ◽  
Clinical Case ◽  
Delayed Diagnosis ◽  
Mandibular Fractures ◽  
Edentulous Patient ◽  
Condylar Fracture ◽  
Physical Finding ◽  
Case Presentation ◽  
Edentulous Patients ◽  
Condylar Fractures

Background. Fractures of the mandible are common in elderly patients, and among them, condylar fractures are the most frequent type. A change in occlusion is the most common physical finding in patients with fractures of the mandible. Therefore, it is challenging to identify mandibular fractures in posterior edentulous patients due to the lack of posterior occlusal contacts. It is crucial to do radiological investigations in such patients to exclude fractures. Case Presentation. This article describes a case of delayed diagnosis of a unilateral mandibular condylar fracture for a week’s duration and treating the condition as temporomandibular pathology in a posterior edentulous, 52-year-old patient. Conclusion. This clinical case highlights the importance of radiological investigations and occlusal analysis for early diagnosis of condylar fractures, particularly in posterior edentulous patients, lacking posterior occlusal contacts.

scholarly journals Recombinant adenovirus causes prolonged mobilization of macrophages in the anterior chamber of mice

2021 ◽  
Author(s):  
Kacie J Meyer ◽  
Danielle Pellack ◽  
Adam J Hedberg-Buenz ◽  
Nicholas Pomernackas ◽  
Dana Soukup ◽  
...  
Keyword(s):  
Recombinant Adenovirus ◽  
Cell Types ◽  
Slit Lamp ◽  
Correct Treatment ◽  
Intraocular Injection ◽  
Lack Of Information ◽  
Corneal Opacities ◽  
Corneal Damage ◽  
Sequential Images

Purpose: Ocular tissues of mice have been studied in many ways using replication deficient species C type 5 adenoviruses (Ad5) as tools for manipulating gene expression. While refinements to injection protocols and tropism have led to several advances in targeting cells of interest, there remains a relative lack of information concerning how Ad5 may influence other ocular cell types capable of confounding experimental interpretation. Here, a slit-lamp is used to thoroughly photodocument the sequalae of intraocular Ad5 injections over time in mice, with attention to potentially confounding indices of inflammation. Methods: A cohort of C57BL/6J mice were randomly split into 3 groups (Virus, receiving unilateral intraocular injection with 5x107 pfu of a cargo-less Ad5 construct; Saline, receiving unilateral balanced salt solution injection; and Naïve, receiving no injections). A total of 52 eyes from 26 mice were photodocumented via slit-lamp at 4 timepoints (baseline, 1, 3, and 10 weeks following initiation of the experiment) by an observer masked to treatments and other parameters of the experimental design. Following the last in vivo exam, tissues were collected. Based on the slit-lamp data, tissues were studied via immunostaining with the macrophage marker F4/80. Results: The masked investigator was able to use the sequential images from each mouse to assign each mouse into its correct treatment group with near perfect fidelity. Virus injected eyes were characterized by corneal damage indicative of intraocular injection and a prolonged mobilization of clump cells on the surface of the iris. Saline injected eyes had only transient corneal opacities indicative of intraocular injections, and Naïve eyes remained normal. Immunostaining with F4/80 was consistent with ascribing the clump cells visualized via slit-lamp imaging as a type of macrophage.

scholarly journals Case report of von willebrand disease after tonsillotomy and adenotomy in a child

2021 ◽  
Vol 20 (1) ◽  
pp. 89-92
Author(s):  
S. S. Makhmudov ◽  
◽  
A. A. Ochilzoda ◽  
F. P. Dzhamolov ◽  
A. Z. Mutalibov ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Practice ◽  
Surgical Treatment ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
Von Willebrand Disease ◽  
Rare Occurrence ◽  
Von Willebrand

The authors present a clinical case of von Willebrand disease detected after tonsillotomy and adenotomy in a child. The peculiarity of this observation lies in the rare occurrence of von Willebrand disease in clinical practice, as well as the manifestation of the clinical manifestations of this pathology against the background of surgical treatment in a child.

Signs of temporomandibular joint dysfunction in individuals with different dentition defects and unequal preservation of antagonist pairs of teeth

2021 ◽  
pp. 52-58
Author(s):  
I.S. Redinov ◽  
Ye.A. Pylaeva ◽  
O.O. Strakh ◽  
B.A. Lysenko
Keyword(s):  
Hearing Loss ◽  
Early Diagnosis ◽  
Temporomandibular Joint ◽  
Pathological Process ◽  
Orthopedic Treatment ◽  
Temporomandibular Joint Dysfunction ◽  
Significant Frequency ◽  
System A ◽  
Lower Jaw ◽  
Opening And Closing

As a result of examination and questionnaire of 143 patients who applied for orthopedic treatment of defects of teeth and dental rows, it was found that signs of dysfunction of temporomandibular joint with preserved dental rows are diagnosed in 36—55% cases, and with defects of dental rows — in 45—90% cases. The absence of eighth teeth in the dental row does not significantly change the functional state of the dental-jaw system. A statistically significant frequency of signs of EHS dysfunction has been identified among individuals having terminal dentition defects.In patients with terminal dentition defects, each 3rd patient is diagnosed with cochleovestibular syndrome, and in each 2nd, sounds are determined in the area of VNHS when the lower jaw moves. It has been found that if 15—13 and 12—11 pairs of antagonist teeth are preserved, the signs of dysfunction are determined in 55—45% cases, if the number of teeth having antagonists is reduced to 10—5 (in 90.0% these are patients with preserved 7—8 pairs of antagonist teeth), then the frequency of dysfunction signs increases to 75.0% (t1-3=1.33; t2-3=2.00), in such patients significantly more often — in 75.0% of cases, mandibular deviation is diagnosed when opening and closing the mouth than in persons with a large number of preserved antagonist teeth, respectively 55.0% (t=2.66) and 45.0% (t=3.93) in 1 and 2 groups. Thus, the identification of such signs as crunching, clicking in the joints, hearing loss or tinnitus, suggests the presence of intra-articular disorders in such patients. The deviation of the jaw from its main trajectory when opening the mouth indicates the possible involvement of the masticators muscles in the pathological process. All this requires the dentist to carry out early diagnosis and timely orthopedic treatment.

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