Current international guidelines for the diagnosis and treatment of acute pancreatitis in children
The article presents current data on the etiology, diagnosis and treatment of acute pancreatitis in children. Over the past 10-15 years, the incidence of pancreatitis has increased and is 3.6-13.3 cases per 100,000 children. According to the results of an international study INSPPIRE a group of researchers involving in to the study of pediatric pancreatitis gave a definition of acute, acute recurrent and chronic pancreatitis and developed clinical guidelines for the management of this pathology in children. Acute pancreatitis is a polyetiological disease, the causes of which may be abnormalities in the development of the pancreatobiliary system, drugs, injuries, infections, systemic diseases. Diagnosis is based on clinical manifestations and laboratory and instrumental data. Clinically acute pancreatitis is manifested by abdominal, dyspeptic and asthenic syndromes. Particular attention is paid to the timely diagnosis of pancreatitis in children with unexplained abdominal pain syndrome. In such cases, it is mandatory to determine the level of amylase and lipase. Transabdominal ultrasound is the screening method among instrumental methods. Computed tomography and magnetic resonance imaging are necessary imaging techniques for suspected pancreatic necrosis. Magnetic resonance cholangiopancreatography, in turn, plays an important role in the diagnosis of anomalies and lesions of the biliary and pancreatic ducts. There are modern classification, diagnostic criteria of acute pancreatitis, laboratory and instrumental methods of the diagnosis and approaches to the treatment in children in the article.