scholarly journals Asthmatic status in pediatric practice. Clinical case

2019 ◽  
Vol 36 (4) ◽  
pp. 88-96
Author(s):  
N. A. Ilyenkova ◽  
L. V. Stepanova ◽  
O. S. Konopleva ◽  
O. V. Alekseeva ◽  
S. Yu. Pastukhova
Keyword(s):  
Bronchial Asthma ◽  
Clinical Case ◽  
Self Control ◽  
Public Health Care ◽  
Severe Exacerbation ◽  
Severe Attack ◽  
Medical Observation ◽  
Global Issue ◽  
Sickness Rate ◽  
Rational Therapy

Bronchial asthma (BA) is a global issue of public health care that is connected with a stable tendency to sickness rate growth. In Russia, mortality rate from BA exacerbation is one of the highest in the world. The most severe attack of BA is considered as asthmatic status (AS) and needs resuscitation measures. Despite the fact that death from BA occurs as a result of acute severe attack (often asthmatic status), it is almost always the consequence of previous incorrect treatment or the absence of proper medical care and observation. The paper presents a clinical case of asthmatic status in a twelve-year old child, which was complicated by spontaneous pneumothorax. The cause of the development of threatening status in a child with bronchial asthma was the absence of basic anti-inflammatory therapy and proper medical observation. The absence of rational therapy and regular observation, rendered to BA patient by a physician of primary care link with training of self-control and self-observation habits, can cause the development of the most severe exacerbation asthmatic status. A timely hospitalization of AS patients to resuscitation and intensive care unit according to indications will promote faster transfer to pediatric department.

scholarly journals The effectiveness of sanatorium and health resort treatment of bronchial asthma patients in the South coast of Crimea depending on the evergreen cypress’s blossoming period

2016 ◽  
Vol 13 (1) ◽  
pp. 11-15
Author(s):  
S N Belyaeva ◽  
V M Savchenko ◽  
M I Govorun ◽  
M E Pirogova
Keyword(s):  
Bronchial Asthma ◽  
Pollen Season ◽  
Complete Blood Count ◽  
South Coast ◽  
The South ◽  
Health Resort ◽  
Medical Observation ◽  
Asthma Patients ◽  
The Crimea ◽  
Physical Abilities

Background. To study the influence of evergreen cypress blossoming period on the effectiveness of sanatorium and health resort treatment (HRT) of bronchial asthma (BA) patients in the South Coast of Crimea (SCC). Methods. The analysis of the data of 71 patients with BA, the residents of the Crimea was conducted. The survey of BA patients included the questioning, medical observation, physical examination, complete blood count, sputum cytology, lung function examination, motor (physical) abilities by 6 minute steptype test and quality of life. Results. Aeropalinological measurement in the SCC (Yalta) showed that the evergreen cypress’s blossoming period is continuing from February to April inclusive. The highest concentrations of cypress pollen were registered in March and in the first half of April. Efficiency of HRT of BA patients in the SCC did not depend on the pollen season of evergreen cypress. Conclusion. Pollen season of evergreen cypress (February - April inclusive) is not a contraindication for HRT of BA patients in the SCC.

The pharmacotherapy of professional serious bronchial asthma

2020 ◽  
pp. 576-577
Author(s):  
N. V. Vakurova ◽  
T. A. Azovskova ◽  
G. F. Vasukova
Keyword(s):  
Bronchial Asthma ◽  
Combined Therapy ◽  
Tiotropium Bromide ◽  
Severe Exacerbation ◽  
Functional Parameters ◽  
Long Acting

In patients with severe bronchial asthma (BA) of professional origin, with the additional appointment of Tiotropium bromide on the background of combined therapy with inhaled glucocorticosteroids and long-acting b2-agonists, functional parameters improve, the proportion of days with good BA control increases, the total number of exacerbations decreases and the period increases to the first severe exacerbation.

scholarly journals Strategy of Rational Therapy of Acute Respiratory Infections in Patients with Comorbidity

2020 ◽  
Vol 8 (2) ◽  
pp. 77-83 ◽  
Author(s):  
T. A. Ruzhencova ◽  
Daria А. Khavkina ◽  
Natalia A. Meshkova ◽  
Pavel V. Chukhliaev ◽  
Alexander A. Garbuzov
Keyword(s):  
Chronic Diseases ◽  
Clinical Case ◽  
Respiratory Infections ◽  
Degradation Products ◽  
Antiviral Treatment ◽  
Acute Respiratory Infections ◽  
Treatment Regimens ◽  
Rational Therapy ◽  
Causal Treatment ◽  
Safe Approach

Abstract. The paper discusses specific features of acute respiratory infections (ARI) progression in patients with comorbidity. The relevance of this study is accounted for by severe progression of ARIs in this group of patients, as well as by specific considerations of combining causal treatment of infections with life-long treatment of chronic diseases.The aim of the study was to use a clinical case to substantiate an optimal treatment strategy for influenza and associated complications in a comorbid patient.Results: the analysis of the clinical case showed that an unfavourable course of ARI in the patient was due to the lack of timely antiviral therapy, adverse effects of paracetamol during statin therapy, exposure to pneumonia pathogen degradation products, general intoxication, and immune response. The compromised medical history contributed to the development of severe complications. The paper proposes a strategy for selecting the most eff ective and safe approach to the treatment of ARIs in a comorbid patient.Conclusions: ARIs in patients with chronic diseases entail increased risks of complications that may arise both due to specific characteristics of the infection and unfavourable combination of drugs. Treatment regimens for infl uenza and other ARIs in comorbid patients should be eff ective and timely. Early antiviral treatment is especially important in patients with comorbidity. When choosing a treatment regimen, it is necessary to assess potential benefi ts of pharmacotherapy as well as associated risks, including those related to previously prescribed medicines. 

scholarly journals Biological drugs in the therapy of atopic dermatitis and bronchial asthma: focus on dupilumab

2021 ◽  
pp. 129-137
Author(s):  
Vera A. Reviakina ◽  
Natalia A. Geppe ◽  
Aleksandr B. Malakhov ◽  
Oleg V. Kaliuzhin ◽  
Natalia G. Astaf'eva ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Targeted Therapy ◽  
Bronchial Asthma ◽  
Inflammatory Disease ◽  
Clinical Case ◽  
Allergic Diseases ◽  
Significant Progress ◽  
Biological Drugs ◽  
The Past

Significant progress has been made over the past decade in the treatment of allergic diseases such as atopic dermatitis and bronchial asthma. Dupilumab, which targets interleukin IL-4 and IL-13, has become an innovative targeted therapy. Immunobiologic therapy with the interleukin inhibitor is indicated for patients with moderate to severe uncontrolled atopic dermatitis, moderate to severe eosinophilic phenotype of uncontrolled Bronchial asthma and patients with poorly controlled severe chronic polyposis rhinosinusitis. A clinical case and recent data on the use of dupilumab for the treatment of type 2 inflammatory disease and prospects for its use are discussed.

scholarly journals Сlinical case of focal alopecia in a child with atopy

2021 ◽  
Vol 23 (1) ◽  
pp. 191-196
Author(s):  
A. A. Barilo ◽  
S. V. Smirnova ◽  
I. M. Olyanina
Keyword(s):  
Allergic Rhinitis ◽  
Bronchial Asthma ◽  
Hair Loss ◽  
Clinical Case ◽  
Skin Prick Testing ◽  
Skin Testing ◽  
Calcineurin Inhibitors ◽  
Hair Follicles ◽  
Autoimmune Response ◽  
High Concentration

Alopecia areata is a common inflammatory immune-mediated disorder in which autoimmune response is triggered against hair follicles, thus leading to non-scarring hair loss on the scalp, face and other parts of the skin. Despite numerous studies concerning this issue, today there is no consensus on the etiology and pathogenesis of focal alopecia. In the literature, special attention is paid to association of focal alopecia with autoimmune diseases, such as rheumatoid arthritis, celiac disease, type 1 diabetes, psoriasis, autoimmune thyroiditis, vitiligo. Recent studies have identified the association of focal alopecia with atopic diseases (allergic rhinitis, bronchial asthma, atopic dermatitis) and the early debut of severe forms of hair loss. The aim of this study was to present a clinical case of focal alopecia in an 8-year-old girl with atopic bronchial asthma and seasonal allergic rhinitis. As based on detection of eosinophilia in peripheral blood and a high concentration of total IgE in serum, one may assume that atopic alopecia is the cause of focal hair losses in a child with atopy. The patient underwent skin prick testing, in order to determine sensitization for food components, pollen and fungal allergens. As a result of skin testing, a hyperergic reaction (> 15 mm in diameter) to tree pollen was revealed, a positive response (6-9 mm) to oatmeal, a weakly positive reaction (3-5 mm) to whole chicken egg, carrots, tomato, apple, pear, pollen of meadow, cereal, weed grasses was also revealed. With regard of these allergological data, an individual diet was recommended with the elimination of causally significant allergens (including those eliciting weakly positive reactions), external treatment, i.e., topical calcineurin inhibitors administered for 1 month. One month later, an improvement of the pathological process was registered, and 6 months from the start of therapy, complete restoration of hair follicles was noted in the focus of alopecia. The patient was monitored for a year, no complaints of hair loss were noted. The positive effect of elimination against the background of the appropriate elimination diet with respect to causally significant allergens, was also noted when treating her for respiratory allergy, i.e., the patient did not have seasonal manifestations of hay fever over the next pollination period. This clinical case is demonstrated in order to draw special attention of dermatologists, allergologists, immunologists, general practitioners to the issues of focal alopecia in children against the background of typical allergic diseases.

CLINICAL CASE: CHRONIC BRONCHITIS AS A RISK FACTOR FOR UNCONTROLLED BRONCHIAL ASTHMA

2020 ◽  
Vol 6 (1) ◽  
pp. 43-47
Author(s):  
M. Gaysaev ◽  
E. Gancgorn
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Chronic Bronchitis ◽  
Bronchial Asthma ◽  
Clinical Case ◽  
Acute Stage

M.O. GAISAEV, E.V. GANTSGORN A clinical case of a 55-year-old patient with persistent moderate uncontrolled bronchial asthma and acute stage of chronic bronchitis is described. In the aspect of etiopathogenetic features and modern approaches to the treatment of this pathology, the tactics of the pharmacotherapy performed are analyzed on the example of this patient. The presented clinical case demonstrates the feasibility of a differentiated approach to the treatment of patients with chronic bronchitis as one of the important risk factors for the progression of bronchial asthma.

scholarly journals BRONCHIAL ASTHMA AS A PROBLEM OF OCCUPATIONAL PATHOLOGY (CLINICAL CASE)

2021 ◽  
Vol 2021 (3) ◽  
pp. 56-60
Author(s):  
A. V. Basanets ◽  
O. V. Ermakova
Keyword(s):  
Allergic Rhinitis ◽  
Occupational Health ◽  
Bronchial Asthma ◽  
Occupational Diseases ◽  
Clinical Case ◽  
Lower Lobe ◽  
State Institution ◽  
Animal Origin ◽  
Pulmonary Insufficiency ◽  
Medical Sciences

BRONCHIAL ASTHMA AS A PROBLEM OF OCCUPATIONAL PATHOLOGY (CLINICAL CASE) A. V. Basanets, O. V. Ermakova State Institution «Kundiiev Institute of Occupational Health of the National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine Abstract. Aim of the study: to analyze a clinical case of occupational bronchial asthma in a librarian with many years of experience, which was diagnosed in the Clinic of occupational diseases of the State Institution «Kundiiev Institute of Occupational Health of the National Academy of Medical Sciences of Ukraine». Materials and research methods: Patient`s medical history, results of clinical, radiological, laboratory and functional examinations. Research results. The examined patient B., 63 years old, worked as a librarian for more than 40 years. The diagnosis was established: Bronchial asthma, ІІІ stage, moderate-severe course, uncontrolled, persistent, phase of exacerbation, basal and lower lobe pneumosclerosis, pulmonary insufficiency І-ІІ stage. Year-round allergic rhinitis — occupational diseases (in the profession for more than 40 years, has been in contact with dust of plant and animal origin) Diagnoses are confirmed by physical examination data, results of clinical laboratory, functional and imaging examination, and data on working conditions. Conclusion: An analysis of epidemiological data on occupational bronchial asthma in Ukraine in recent years has shown a decrease in the incidence, while this indicator is increasing throughout the world. Given the current situation, special attention should be paid to the need for a serious improvement in the training of family doctors, therapists and pulmonologists in occupational pathology. Improving the quality of preliminary (hiring) and periodic medical examinations is of great importance for improving the diagnosis of occupational bronchial asthma. Key words: occupational bronchial asthma, allergic rhinitis, allergens. Angela V. Basanets State Institution «Kundiiev Institute of Occupational Health | of the National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine Head of the department of occupational pathology Corresponding member of NAMS of Ukraine, professor 75, Saksaganskogo str., 01033, Kyiv, Ukraine [email protected] Аsthma and Allergy, 2021, 3, P. 56–60.

scholarly journals Rational therapy of asthma in children with inhaled corticosteroids

2016 ◽  
Vol 1 (1) ◽  
pp. 63-67
Author(s):  
N. A. Geppe ◽  
N. G. Kolosova ◽  
S. I. Shatalina
Keyword(s):  
Bronchial Asthma ◽  
Inhaled Corticosteroids ◽  
Persistent Asthma ◽  
Initial Therapy ◽  
Rational Therapy ◽  
Asthma In Children ◽  
Effective Drugs

Currently, the most effective drugs for the treatment and management of bronchial asthma (BA) are inhaled corticosteroids (ICS) which, according to global guidelines, are indicated as initial therapy for persistent asthma of any severity.

Experience of using dupilumab in the treatment of severe bronchial asthma: a clinical case

Pharmateca ◽  
2021 ◽  
Vol 10_2021 ◽  
pp. 124-128
Author(s):  
G.R. Sergeeva Sergeeva ◽  
I.V. Tsukanova Tsukanova ◽  
T.V. Demyanova Demyanova ◽  
A.V. Emelyanov Emelyanov ◽  
◽  
...  
Keyword(s):  
Bronchial Asthma ◽  
Clinical Case

scholarly journals Design and Implementation of an Information System for Self-Control of Bronchial Asthma by Patients

2020 ◽  
Vol 5 (2) ◽  
pp. 56-62
Author(s):  
Konrad Glinka ◽  
◽  
Anatoliy Melnyk
Keyword(s):  
Information System ◽  
System Design ◽  
Bronchial Asthma ◽  
Important Task ◽  
Self Control ◽  
Main Function ◽  
Basic Information ◽  
Information System Design ◽  
Design And Implementation ◽  
Selection Of

The aim of this article is to develop information system for people with bronchial asthma. The main function of the information system described in the article is enabling self- control of bronchial asthma by patients. By controlling asthma correctly, patients can reduce the symptoms of asthma. The most important task solved before the information system design was a selection of the asthma parameters which can be monitored and implemented in it. The information system consists of two main elements: a database and an application. The article describes the technologies used to create these elements. Moreover, the article provides information about connection between the database and the application. The article also includes basic information about asthma and describes the information system work.

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