scholarly journals Pengaruh Pemberian Ekstrak Daun Gaharu (Grynops versteegii) terhadap Stres Transportasi pada Broiler Jantan

2021 ◽  
Vol 21 (2) ◽  
pp. 165-171
Author(s):  
Ujang Suryadi ◽  
Anang Febri Prasetyo ◽  
Erfan Kustiawan ◽  
Urfa Khoirotun Khisan

ABSTRACT. Penelitian bertujuan mengetahui pengaruh penambahan ekstrak daun Gaharu (Grynops verstegii) sebelum transportasi terhadap stres transportasi dan penyusutan bobot badan pada broiler jantan. Materi yang digunakan sebagai sampel yaitu 60 ekor dari 200 ekor broiler jantan yang dipelihara, dan ekstrak daun Gaharu dari hasil destilasi. Penelitian menggunakan metode eksperimental dengan Rancangan Acak Lengkap (RAL) dengan uji lanjut Duncan’s. Broiler jantan yang digunakan dalam penelitian terbagi menjadi 4 perlakuan level pemberian ekstrak daun Gaharu yang berbeda. Pemberian ekstrak daun Gaharu berdasarkan pada bobot badan (BB) broiler, yaitu P0 (tanpa pemberian ekstrak daun Gaharu sebagai kontrol ), P1 (250 mg/kg BB), P2 (300 mg/kg BB), P3 (350 mg/kg BB), setiap perlakuan memiliki lima ulangan dan setiap ulangan menggunakan 3 ekor. Parameter yang diamati adalah penyusutan bobot badan, frekuensi denyut jantung, suhu tubuh, dan frekuensi Pernafasan. Hasil penelitian menunjukkan bahwa penambahan ekstrak daun Gaharu (Grynops verstegii) tidak berpengaruh nyata (P0,05) terhadap persentase susut bobot badan broiler, frekuensi denyut jantung, suhu tubuh dan frekuensi pernafasan. Disimpulkan bahwa pemberian ekstrak daun Gaharu sebelum transportasi pada broiler tidak berpengaruh terhadap penurunan stres setelah transportasi hal ini ditunjukkan oleh perubahan suhu tubuh, frekuensi pernafasan, peningkatan denyut jantung dan penyusutan bobot badan yang tidak berbeda nyata (P0.05) dibandingkan dengan kontrol.  (The effect of agarwood leaf extract (Grynops versteegii) on transport stress in male broilers) ABSTRAK. This study aims to determine the effect of adding agarwood leaf extract a source of antioxidants before transportation on body weight loss and the physiological conditions of broilers. The materials used were 60 male broilers as samples and agarwood leaf extract obtained through the extraction process using the distillation method. This study used experimental methods with a completely randomized design (CRD) with Duncan's test. The broilers used in the study consisted of 4 treatment groups with different levels of Gaharu leaf extract, they were P0 (control), P1 (250 mg/kg body weight, P2 (300 mg/kg body weight), P3 (350 mg/kg body weight), each treatment was repeated five times and each repetition used 3 individuals. The parameters observed were weight loss, heart rate frequency, increase in body temperature, and respiratory rate. The results showed that the addition of agarwood leaf extract (Grynops verstegii) had no significant effect (P 0.05) on the percentage of broiler body weight loss, heart rate frequency, increased body temperature and respiratory frequency. It was concluded that the addition of agarwood leaf extract before transportation could not reduce body weight loss and the physiological conditions of broilers.


2018 ◽  
Vol 15 (2) ◽  
pp. 40-45
Author(s):  
Marina O. Galieva ◽  
Ekaterina A. Troshina ◽  
Nataliya V. Mazurina ◽  
Anna P. Volynkina ◽  
Andrey V. Artiushin ◽  
...  

Aims. To study of the polymorphisms of the TPN2 and GNB3 genes in obese patients and their effect on weight loss in patients on sibutramine therapy. Materials and methods. The research study included 118 patients with exogenous-constitutional obesity who received Reduxin (sibutramine + CMC) at the dose of 10 mg. Term follow-up was 3 months. A genetic study was performed to assess ТРН2 and GNB3 gene polymorphisms. The response to the therapy was evaluated after 3 months by the dynamics of body weight. Results. In the study the G703T polymorphism of the GNB3 gene showed that during 3 months of observation, carriers of the TT genotype had a greater decrease in body weight in comparison with carriers of the allele C -8 kg (-12; -5) vs. -5 kg (-8; -3), p = 0.018. In carriers of different variants of the genotype of the TPH2 gene (polymorphism C825T), there was no difference in body weight dynamics with sibutramine therapy. There was no correlation between the foresaid polymorphisms of the TPH2 and GNB3 genes with the indices of blood pressure and heart rate. Conclusions. 1. The result of sibutramin therapy may depend on genetic factors: in carriers of the TT-genotype C825T of the GNB3 gene the body weight loss was higher than among the carriers of the C allele. 2. Changes in blood pressure and heart rate did not show any statistically significant relationship with polymorphisms of the TPH2 and GNB3 genes.



2018 ◽  
Vol 15 (2) ◽  
pp. 40-45
Author(s):  
Marina O Galieva ◽  
Ekaterina A Troshina ◽  
Nataliya V Mazurina ◽  
Anna P Volynkina ◽  
Andrey Artiushin ◽  
...  

AIMS. To study of the polymorphisms of the TPN2 and GNB3 genes in obese patients and their effect on weight loss in patients on sibutramine therapy. MATERIALS AND METHODS. The research study included 118 patients with exogenous-constitutional obesity who received Reduxin (sibutramine + CMC) at the dose of 10 mg. Term follow-up was 3 months. A genetic study was performed to assess ТРН2 and GNB3 gene polymorphisms. The response to the therapy was evaluated after 3 months by the dynamics of body weight. RESULTS. In the study the G703T polymorphism of the GNB3 gene showed that during 3 months of observation, carriers of the TT genotype had a greater decrease in body weight in comparison with carriers of the allele C – -8 kg (-12; -5) vs. -5 kg (-8; -3), p = 0.018. In carriers of different variants of the genotype of the TPH2 gene (polymorphism C825T), there was no difference in body weight dynamics with sibutramine therapy. There was no correlation between the foresaid polymorphisms of the TPH2 and GNB3 genes with the indices of blood pressure and heart rate. CONCLUSIONS. 1. The result of sibutramin therapy may depend on genetic factors: in carriers of the TT-genotype C825T of the GNB3 gene the body weight loss was higher than among the carriers of the C allele. 2. Changes in blood pressure and heart rate did not show any statistically significant relationship with polymorphisms of the TPH2 and GNB3 genes.



2019 ◽  
Vol 19 (2) ◽  
pp. 113-121
Author(s):  
Lendrawati Lendrawati ◽  
Rudi Priyanto ◽  
Mohamad Yamin ◽  
Anuraga Jayanegara ◽  
Wasmen Manalu ◽  
...  

ABSTRAK. Penelitian ini bertujuan untuk mengevaluasi respon fisiologis dan penyusutan bobot badan domba lokal jantan terhadap transportasi dengan posisi yang berbeda pada kendaraan. Penelitian ini menggunakan 10 ekor domba lokal jantan yang berumur 8-10 bulan dengan rataan bobot badan 16,11 ± 2,27 kg. Penelitian ini menggunkan Rancangan Acak Lengkap dua  faktor dengan 5 ulangan. Faktor pertama adalah: posisi domba di kendaraan terdiri dari: posisi berdiri dan berbaring. Faktor kedua adalah waktu pengambilan sampel yaitu: sebelum dan setelah transportasi. Semua domba perlakuan diangkut dalam satu mobil Pick up  selama 8 jam perjalanan dengan tingkat kepadatan yang sama yaitu 0,27 m2/ekor. Data bobot badan, suhu rektal, laju respirasi, denyut nadi, hormon kortisol, glukosa, kreatinin, hemoglobin dan hematokrit dikumpulkan sebelum dan setelah transportasi. Hasil penelitian menunjukkan bahwa tidak terdapat interaksi yang nyata (P0,05) antara posisi domba dikendaraan dengan waktu pengambilan sampel pada semua parameter (kecuali denyut nadi). Penempatan domba dengan posisi berdiri dan berbaring selama 8 jam transportasi memperlihatkan respon yang sama terhadap penyusutan bobot badan, suhu rektal, laju pernapasan, hormon kortisol, konsentrasi glukosa, kreatinin, hemoglobin dan hematokrit. Kesimpulan penelitian ini adalah penempatan dengan posisi berdiri dan berbaring di kendaraan selama 8 jam transportasi memperlihatkan respon fisiologis dan penyusutan bobot badan yang sama pada domba lokal jantan.  (Physiological responses and body weight loss of male local sheep during transportation with different position on the vehicle) ABSTRACT. The aim of this study was to evaluate  the physiological responses and body weight loss of  males local sheep to transportation with different positions on the vehicle. Ten males sheep with 16.11±2.27 kg of body weight and 8-10 months in aged were used in this study. Completely Randomized Design with two factors was used in this study. The first factor was  positions on the vehicle (standing and lying down) and the second factors was sampling times (before and after transportation).  All of sheep were transported in one Pick up (Mitsubishi L 300) for 8 hours with similar of density level of 0,27 m2/head. Data on body weight, rectal temperature, respiration rate, pulse, cortisol, glucose, creatinine, hemoglobin and hematocrit were collected before and after transportation. Results showed  there was no significant interaction (P 0.05) between the position of the sheep in the vehicle with the time of sampling in all parameters (except pulse rate). Placing of sheep with standing and lying down position for 8 hours of transportation showed the same responses  for body weight loss, rectal temperature, respiratory rate, cortisol level, glucose concentration, creatinine, hemoglobin and hematocrit. Based on those findings, it can be concluded that  standing and lying position in the vehicle for 8 hours of transportation shows the similar effect on the physiological responses and body weight loss of  local male sheeps. 



2021 ◽  
pp. 1971-1976
Author(s):  
Ujang Suryadi ◽  
Erfan Kustiawan ◽  
Anang Febri Prasetyo ◽  
Shokhirul Imam

Background and Aim: The open house cage is mainly influenced by the environmental heat from the sun and the heat released by the chicken. Heat stress can affect physiological conditions so that it has an impact on decreasing productivity. This study aims to determine the effect of agarwood leaf extract in feed on the physiological condition and production performance of broilers experiencing heat stress and to generate prediction equations for the optimal level of the extract in feed. Materials and Methods: A total of 200 22-day-old broilers (Cobb 500™) underwent four treatments with five replications each, namely, feed without agarwood leaf extract (control) (T0), and feed with 250 (T1), 300 (T2), and 350 mg of agarwood leaf extract/kg body weight (T3). The parameters observed include physiological condition (heart rate, respiratory frequency, and body temperature) as well as production performance (feed consumption, body weight gain [BWG], and feed conversion). Results: The administration of agarwood leaf extract significantly (p<0.05) decreased heart rate and respiratory frequency. However, there was no significant difference (p>0.05) in body temperature, glucose levels, hemoglobin and erythrocyte concentrations, as well as production performance which include weight gain, feed consumption, and feed conversion ratio. Meanwhile, broilers treated with agarwood leaf extract had a significantly lower heart rate and respiratory frequency (p<0.05) compared to the control. However, broilers given agarwood leaf extract showed better body weight, consumption, and ration conversion compared to the control. Conclusion: Agarwood leaf extract in feed reduces heart rate and respiratory frequency but has no significant effect on body temperature and hematological parameters (glucose levels, hemoglobin, and erythrocyte concentrations) as well as production performance (feed consumption, weight gain, and feed conversion). These results indicate that the administration of 350 mg/kg body weight agarwood leaf extract is most effective to reduce feed consumption and increase BWG.



Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1965-P
Author(s):  
TEAYOUN KIM ◽  
JESSICA P. ANTIPENKO ◽  
SHELLY NASON ◽  
NATALIE PRESEDO ◽  
WILLIAM J. VAN DER POL ◽  
...  


2018 ◽  
Vol 44 (1) ◽  
Author(s):  
Ayako Ito ◽  
Aya Nozaki ◽  
Ichiro Horie ◽  
Takao Ando ◽  
Atsushi Kawakami


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