High toluene exposure risk increases risk of olfactory dysfunction in furniture workers
BACKGROUND<br />Few studies have investigated the impact on olfactory functioning of<br />occupational exposure to toluene, an industrial solvent used in paints and<br />cleaning fluids. The estimated olfactory dysfunction prevalence is 0.5–<br />5%. Patients frequently do not complain about olfactory dysfunction.<br />However, occupational exposure to chemicals may affect workers’ health<br />and safety, because of their continuous inhalation. This study aimed to<br />examine the relationship between toluene exposure and olfactory<br />dysfunction in furniture workers.<br />METHODS<br />This was a cross-sectional study involving 65 workers. Data collection<br />was by observation and interview on demographic characteristics, history<br />of habits, and symptoms of chronic rhinitis. Risk of exposure scores were<br />evaluated from potential hazard, exposure level, duration of employment,<br />type of work, use of masks, ventilation of work space, and education and<br />training. Olfactory function was tested using Sniffin’ Sticks, and<br />determination of environmental toluene level was by personal sampling.<br />The odds ratio was used to test correlations between variables.<br />RESULTS<br />Only 44 subjects could be analyzed, 37 (84.1%) of whom had olfactory<br />dysfunction. Workers with high toluene exposure had a significantly 12.5-<br />fold risk of olfactory dysfunction in comparison with those with low<br />exposure (OR=12.5; CI 95% 1.35 – 115.79).<br />CONCLUSIONS<br />Toluene exposure increases risk of olfactory dysfunction in furniture<br />workers. Olfactory function testing should be considered for initial<br />screening or periodic testing of furniture workers. Low toluene levels with<br />a high proportion of olfactory dysfunction indicate that olfactory dysfunction<br />is an early negative impact of chemical inhalation.