scholarly journals Comparative Study on Phytochemical Composition and In Vitro Radical Scavenging Activity of Ethanolic Extracts of Landolphia lanceolata and Nutraceutical-C24/7

2018 ◽  
Vol 10 ◽  
pp. 36-44
Author(s):  
Carole Nweze Chibuzo ◽  
Abdurrasheed Yusuf Hauwa ◽  
Ahmed Zubairu
Keyword(s):  
Vitamin C ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Vitamin B ◽  
Scavenging Activity ◽  
Dpph Radical ◽  
Fruit Extract ◽  
Phytochemical Composition ◽  
Ethanolic Extracts

This study investigated the phytochemical composition andin-vitroradical scavenging activity of ethanolic extracts of Nutraceutical-C24/7 andLandolphialanceolatafruit. Phytochemical screening ofLandolphialanceolatafruit extractindicated the presence of phenols, flavonoids, saponins, alkaloids, terpenoids, tannins, triterpenoids and steroids. While nutraceutical-C24/7 showed precence of with exception of saponins, terpenoids and triterpenoids. Some of the identified Phytochemicals and vitamins concentrations quantified were higher inLandolphialanceolatafruit extractthan nutraceutical-C24/7 with statistically significant difference (p<0.05) with the former having flavonoids 0.062±0.00mg/ml, phenol 0.097±0.00mg/ml, vitamin C 206±42mg/dL, vitamin B154.16±0.00mg/dL and vitamin B20.11±0.00mg/dL while, Nutraceutical-C24/7 extract had flavonoid 0.117±0.00mg/ml, phenol 0.032±0.00, vitamin C 102.24±0.00mg/dL, vitamin B123.36±0.00mg/dL, and vitamin B20.067±0.00mg/dL. The study also showed that at higher concentration, DPPH radical, ferric ion, and hydrogen peroxide the extracts radical scavenging activity increased. The study showed that the extracts scavenging activities at different concentrations had higher percentage inhibition on DPPH radical, reducing power of ferric ion capabilities and reducing composition of hydrogen peroxide indicated that ethanolic extract ofLandolphialanceolatafruits showed statistically significant different (p<0.05) when compared with ethanolic extract of Nutraceutical-C24/7. Standard vitamin C percentage inhibition for DPPH radical compared well with that ofLandolphialanceolatafruit extract at higher concentration with no statistical significant different (p>0.05).The indigenous functional foodLandolphialanceolatafruit can be concluded to be a good antioxidant that can scavenge, inhibit and quench free radicals. This suggests thatLandolphialanceolatamay be considered a good source and alternative antioxidant for developing countries like Nigeria.

scholarly journals Evaluation of Free Radical Scavenging Activity in Ethanolic Extract from Promising Accessions of Curcuma aeruginosa RoxB.

Molekul ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. 133 ◽  
Author(s):  
Waras Nurcholis ◽  
Nurul Khumaida ◽  
Muhamad Syukur ◽  
Maria Bintang
Keyword(s):  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Pharmaceutical Products ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Dpph Radical ◽  
Ic50 Values

This study evaluated the free radical scavenging activity in ethanolic extracts from 20 accessions of Curcuma aeruginosa. The radical scavenging activity of the extract accessions was investigated with 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. IC50 values for DPPH radical scavenging activity ranged from 89.81 to 505.65 µg mL-1. Based on IC50 values, twenty accessions of C. aeruginosa can be divided into three groups: strong (two accessions); moderate (seventeen accessions); and low (one accession) of DPPH scavenger. Sukoharjo (SH) and Muara Bungo (MB) showed promising accessions for antioxidant potential, thus these accessions important to selection for future breeding program in pharmaceutical products.

scholarly journals Radical Scavenging Activity Combination of Sambiloto (Andrographis paniculata Nees.) and Patikan Kebo (Euphorbia hirta L.) Ethanolic Extracts on 2,2-Diphenyl-1-Picrylhidrazyl (DPPH)

2018 ◽  
Vol 23 (3) ◽  
pp. 79
Author(s):  
Andayana Puspitasari Gani ◽  
Suwidjiyo Pramono ◽  
Sudibyo Martono ◽  
Sitarina Widyarini
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Andrographis Paniculata ◽  
Scavenging Activity ◽  
Flavonoid Content ◽  
Euphorbia Hirta ◽  
Ic50 Value ◽  
Ethanolic Extracts ◽  
Dpph Radical Scavenging

Research of radical scavenging activity of sambiloto (Andrographis paniculata Nees) and patikan kebo (Euphorbia hirta L) ethanolic extracts and their combination toward 2,2-Diphenyl-1-Picrylhidrazyl (DPPH) has conducted. Subjects of this experiment comprise sambiloto ethanolic extract, patikan kebo ethanolic extract, dechlorophyllated extract of sambiloto and combinations among those three. Dechlorophyllation by electrocoagulation method is done to reduce chlorophyll content thereby increasing the level of active compound in the sambiloto extract. The results of dechlorophyllation showed that only total flavonoid content in the extract of sambiloto increased, meanwhile the radical scavenging activity results showed that patikan kebo ethanolic extract has the lowest IC50 value (22,36 µg/mL) compared to sambiloto ethanolic extract (IC50 value 499,03 µg/mL). Extract combination may increase DPPH radical scavenging activity of the sambiloto extract (IC50 value 76,06 µg/mL) but not higher than that of patikan kebo single extract.

scholarly journals Evaluation of Antioxidant Activity of fresh Lemon (Citrus lemon L.) peel in Marrakech, Kenitra cities of Morocco and Taiz of Yemen

2020 ◽  
Vol 10 (6) ◽  
pp. 585
Author(s):  
Khaled Abdu ◽  
Rahma Erahioui ◽  
Amina Moutawalli ◽  
Ahmed Zahidi ◽  
Khadija Khedid ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Methanolic Extract ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Scavenging Activity ◽  
Dpph Radical ◽  
Dpph Radical Scavenging Activity ◽  
Lemon Peel ◽  
Dpph Radical Scavenging

<p class="Mabstract">The principal objective of this study was to appraise the variation of antioxidant activity, total phenols, and total flavonoids of fresh lemon peel from regions located Marrakech and Kenitra in Morocco and a region Taiz in Yemen. The test of polyphenol was performed from extracts that were measured using the Folin-Ciocalteu technique. Also, an analysis of Flavonoid was performed of was measured by using the aluminum chloride. The Free radical scavenging activity of lemon extracts was measured by 2,2′-Diphenyl-1-picrylhydrazyl hydrate (DPPH).</p><p class="Mabstract">The DPPH radical scavenging activity of ethanolic extract of fresh lemon peel found to be highest at 200μl concentration, which was 77. 15 %; 67. 88 %; 37.74%. Through it, 50% inhibition (IC50) was obtained to be 92. 04; 153. 55 and 215.407 μg/ml in Marrakech, Kenitra, and Taiz, respectively. As well, the values radical scavenging activity of methanolic extract of the same concentration, which are 82, 77 %, 53, 33 %, and 47,5%. Through it, 50% inhibition (IC50) was obtained to be 145. 6; 179. 17 and 274.899 μg/ml in Marrakech, Kenitra, and Taiz, respectively. But regarding the values radical scavenging activity of essential oil of the same concentration, which is 63.77 %, 42.19 %, and 80.25%. Through it, 50% inhibition (IC50) was obtained to be 155.54; 271.158 and 101.31 μg/ml in Marrakech, Kenitra, and Taiz, respectively. According to the results obtained in our study, the antioxidant activity increases with increased polyphenols and IC50 deficiency in Marrakech, Kenitra, and Taiz<strong>.</strong></p>

Determination of Free Radical Scavenging Potential in Cucumis melo (L). Fruit Extract

2021 ◽  
pp. 5084-5088
Author(s):  
Vidya R ◽  
Kalaivani K
Keyword(s):  
Free Radical ◽  
Cucumis Melo ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Free Radical Scavenging ◽  
Scavenging Activity ◽  
Fruit Extract

The human body has an elaborate antioxidant defence system. Antioxidants are manufactured within the body and may even be extracted from the food like fruits, vegetables, seeds, nuts, meats and oil. Fresh fruits and vegetables are a rich source of antioxidant vitamins such as A, C and E, that prevent cellular damage associated with many diseases. This present investigation was designed to evaluate the radical scavenging activity of ethanolic extract of Cucumis melo fruit. The in vitro free radical scavenging effect of the Cucumis melo (L) fruit extract was assessed by using 1,1 – diphenyl 2-picryl hydrazyl radical (DPPH), ABTS (2, 2’-Azinobis (3-ethyl Benz Thiazoline-6-Sulfonic acid) hydroxyl radical, reducing power and nitric oxide scavenging assay. The scavenging activity of the fruit extract was tested at different concentrations. C.melo fruit extract showed concentration dependant free radical scavenging activity. Ethanol extract of Cucumis melo fruit (EECMF) exhibited maximum scavenging activity against DPPH (64.46%), ABTS (70.52%) hydroxyl radical (62.57%), and nitric oxide (61.18%) in comparison with standard antioxidants. The reducing power of ethanol extract of C.melo fruit was found to be 0.11 at 0.2mg/ml and increased to 0.49 at 1mg/ml. These results clearly indicate that ethanolic extract of C.melo fruit has great potential of free radical scavenging activity and it may be used as a bioactive source of natural antioxidants for pharmacology of functional foods.

scholarly journals Evaluation of the DPPH radical scavenging activity of Kadaliphala (Musa paradisiaca. Linn) and Go-Ksheera (Cow milk) W.S.R. to the concept of Samyoga Viruddha

2020 ◽  
Vol 11 (3) ◽  
pp. 415-418
Author(s):  
Shwetha K ◽  
Shobha Bhat K
Keyword(s):  
Vitamin C ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Cow Milk ◽  
Scavenging Activity ◽  
Dpph Radical ◽  
Dpph Radical Scavenging Activity ◽  
Musa Paradisiaca ◽  
The Individual ◽  
Dpph Radical Scavenging

Certain diets and their combinations have properties opposite to the tissues of the body  which thereby inhibit and interrupt their normalcy and these are described as Viruddha Ahara (incompatible diets) in Ayurveda.  Various types of Viruddha Ahara have been described in the classical texts of Ayurveda and Samyoga Viruddha (incompatability due to the combination) is one among them. Among the various examples quoted for samyoga viruddha, combination of kadaliphala (Musa paradisiaca. Linn) and Go-Ksheera (Cow milk) is one. The present study discusses the DPPH radical scavenging activity of the individual items and the combination of banana and milk. Materials and methods: The antioxidant activities of banana, milk and combination of banana and milk was determined by DPPH (1,1-diphenyl-2-picrylhydrazine) radical scavenging assay in comparison with vitamin C standard. Results: The Percentage inhibition of the discoloration of DPPH by the sample extract was expressed against vitamin C standard. The % inhibition of banana was 62.86 whereas the milk was having 69.01% inhibition. The % inhibition of the combination was 46.21. Conclusion: DPPH radical scavenging activity of combination of kadaliphala (banana) and Go-Ksheera (milk) found a significant decrease in the percentage of inhibition when compared to the individual sample indicating towards the incompatibility in their combination or Samyoga Viruddha.

scholarly journals Study of Antioxidant Activity of Some Medicinal Plants Having High Content of Caffeic Acid Derivatives

Antioxidants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 412 ◽  
Author(s):  
Agnieszka Tajner-Czopek ◽  
Mateusz Gertchen ◽  
Elżbieta Rytel ◽  
Agnieszka Kita ◽  
Alicja Z. Kucharska ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Caffeic Acid ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Scavenging Activity ◽  
Caffeic Acid Derivatives ◽  
Chicoric Acid ◽  
Ethanolic Extracts

Recently, there has been increasing interest in medicinal plants, due to their content of health-promoting compounds, e.g., caffeic acids derivatives. Hence, the aim of this work was to study the antioxidant activity of extracts obtained from the following medicinal plants: caraway (Carum carvi L.), coltsfoot (Tussilago farfara L.), dandelion (Taraxacum officinale F.H.Wigg.), lovage (Levisticum officinale L.), tarragon (Artemisia dracunculus L.) and white mulberry (Morus alba L.), characterized by their high content of caffeic acid derivatives. The water-ethanolic extracts were characterized on average by about 9 times higher contents of caffeic acid derivatives level than water extracts. Both in water and water-ethanolic extracts, the dominant phenolic acid was 5-CQA (5-O-caffeoylquinic acid) and 3,4-diCQA (3,4-dicaffeoylquinic acid), then CCA-1 (chicoric acid isomer 1), which appeared only in water-ethanolic extracts. Extracts from dandelion contained compounds such as CTA (caftaric acid), CCA-1 (chicoric acid isomer 1) and CCA-2 (chicoric acid isomer 2), which were not detected in other plant extracts examined in this work. The water-ethanolic extracts from coltsfoot and tarragon were characterized by a high content of di-caffeoylquinic acids, especially 3,4-diCQA and 3,5-diCQA, respectively. It has been stated that there is a positive correlation between caffeic acid derivatives and antioxidant activity (radical cation scavenging activity (ABTS) and radical scavenging activity (DPPH)), especially in water-ethanolic extract of medicinal plants.

scholarly journals Antiglycation and Antioxidant Properties of Ficus deltoidea Varieties

2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Nur Sumirah Mohd Dom ◽  
Nurshieren Yahaya ◽  
Zainah Adam ◽  
Nik Mohd Afizan Nik Abd. Rahman ◽  
Muhajir Hamid
Keyword(s):  
Antioxidant Activity ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Protein Carbonyl ◽  
Scavenging Activity ◽  
Dpph Radical ◽  
Dpph Radical Scavenging Activity ◽  
Ficus Deltoidea ◽  
Dpph Radical Scavenging

The present study aimed to evaluate the potential of standardized methanolic extracts from seven Ficus deltoidea varieties in inhibiting the formation of AGEs, protein oxidation, and their antioxidant effects. The antiglycation activity was analyzed based on the inhibition of AGEs, fructosamine, and thiol groups level followed by the inhibition of protein carbonyl formation. The antioxidant activity (DPPH radical scavenging activity and reducing power assay) and total phenolic contents were evaluated. After 28 days of induction, all varieties of Ficus deltoidea extracts significantly restrained the formation of fluorescence AGEs by 4.55–5.14 fold. The extracts also reduced the fructosamine levels by 47.0–86.5%, increased the thiol group levels by 64.3–83.7%, and inhibited the formation of protein carbonyl by 1.36–1.76 fold. DPPH radical scavenging activity showed an IC50 value of 66.81–288.04 μg/ml and reducing power activity depicted at 0.02–0.24 μg/ml. The extent of phenolic compounds present in the extracts ranged from 70.90 to 299.78 mg·GAE/g. Apart from that, correlation studies between the activities were observed. This study revealed that seven varieties of Ficus deltoidea have the potential to inhibit AGEs formation and possess antioxidant activity that might be attributed to the presence of phenolic compounds.

Sign in / Sign up

Export Citation Format

Share Document