scholarly journals Pharmacology and Ethnomedicine of the Genus Astragalus

2016 ◽  
Vol 3 ◽  
pp. 46-53 ◽  
Author(s):  
Roman Lysiuk ◽  
Roman Darmohray
Keyword(s):  
Medicinal Plants ◽  
Broad Spectrum ◽  
Antiviral Agents ◽  
Folk Medicine ◽  
Pharmacological Action ◽  
Scientific Data ◽  
Review Article ◽  
Pharmacological Effects ◽  
Herbal Drugs ◽  
Morphological Distribution

The genus Astragalus, consisting of about 3000 species, is a valuable source of herbal drugs. The review article comprises scientific data concerning morphological, distribution and phytochemical characters of the genus. Polysaccharides, saponins, and flavonoids are considered main active principles. Astragalus spp. have long been used as medicinal plants in folk medicine as cardiovascular, antihypertensive, diuretic, choleretic, as well as antimicrobial and antiviral agents. The plants of the genus exhibit a broad spectrum of pharmacological effects, among which major include diuretic, anti-inflammatory, bactericidal, hypotensive, and sedative ones. The review focuses on uses of about 30 Astragalus species in official medicine and ethnomedicine and their pharmacological action.

scholarly journals Pharmacological Effects of Favipiravir on Coronavirus: An Update

2021 ◽  
Vol 14 (02) ◽  
pp. 1087-1095
Author(s):  
Prerna Tejaswi ◽  
Kumar Devashish ◽  
Raj Ranjan Prasad
Keyword(s):  
Research And Development ◽  
Broad Spectrum ◽  
Safety Profile ◽  
Treatment Options ◽  
Specific Treatment ◽  
Antiviral Drugs ◽  
Review Article ◽  
Pharmacological Effects ◽  
Health Crisis ◽  
Novel Virus

The coronavirus pandemic is the worst health crisis of our time. There is a massive upsurge of the cases and no specific treatment options of this novel virus (SARS-CoV-2).Due to no time for research and development of a new drug or a vaccine, old and existing broad spectrum antiviral drugs were tried and tested. Favipiravir showed promising results in mild to moderate COVID-19 infection in small studies. The drug is approved with precaution under emergency use, as its safety profile is still not clear. We have considered every aspect of favipiravir and compiled all the latest information about the drug in this review article.

Herbal Drugs and Natural Products in the light of Nanotechnology and Nanomedicine for Developing Drug Formulations

2020 ◽  
Vol 20 ◽  
Author(s):  
Hiwa M. Ahmed ◽  
Seyed Nabavi ◽  
Sahar Behzad
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Polymeric Nanoparticles ◽  
Vital Role ◽  
Review Article ◽  
The Body ◽  
Biologically Active ◽  
Herbal Drugs ◽  
Herbal Drug ◽  
Drug Formulations

: Natural products and medicinal plants have played a vital role in providing healthcare and ensuring wellbeing for many civilisations since antiquity. It is estimated that around 50% of drugs in the market have a natural product origin especially medicinal plants and herbal drugs, animals, fungi, and marine organisms. Some of these biologically active constituents of extracts have low absorption and distribution which, as a result, leads to loss of bioavailability and efficacy and might hamper their applications in the clinic. To overcome these impediments for the formulation of herbal drugs, food supplements and essential oils, several nanomedical approaches such as liposomes, microemulsions, polymeric nanoparticles, solid lipid nanoparticles (SLNs), liquid crystal systems (LC), and precursor systems for liquid crystals (PSLCs) have been proposed. Nanoparticles have been used to modify and ameliorate the pharmacokinetic and pharmacodynamic properties of different drugs, thus incorporating biotechnological systems may be useful to enhance the bioavailability and bioactivity of herbal drug formulations. Consequently, essential for any natural compounds is the extent of its absorption after being ingested and its ability to be distributed in various tissues or organs of the body. The present review article aims to give an overview regarding the recent advancements in developing herbal drug formulations based on nanoparticle technologies.

Turkish Herbal Medicine in the Treatment of Back Pain

2020 ◽  
pp. 235-251
Author(s):  
Mustafa Eray Bozyel ◽  
Elif Merdamert Bozyel ◽  
Kerem Canli
Keyword(s):  
Back Pain ◽  
Herbal Medicine ◽  
Medicinal Plants ◽  
19Th Century ◽  
Folk Medicine ◽  
Herbal Drugs ◽  
Ancient Times ◽  
Pain Symptoms ◽  
The 19Th Century

The number of plants used for treatments has been steadily increasing since ancient times. There were around 250 herbal drugs used during the Mesopotamian civilization. During the time of the Greeks, 60 medicinal plants were known. During the Arab-Persian civilization, this number increased to about 4,000. At the beginning of the 19th century, the number of known medicinal plants reached 13,000. These herbal drugs are used to treat many diseases, from diabetes to cancer. Back pain and related symptoms rank as the second most common affliction of humankind. One of the proposed methods to control and treat back pain symptoms is traditional folk medicine. This chapter examines the recent ethnobotanical studies to form a compilation on medicinal plants used as Turkish herbal medicine in the treatment of back pain and their local names, parts, and usage forms.

Ethnoveterinary uses of medicinal plants as herbal drugs for sustainable livestock in southern deserts of Sindh Pakistan

2020 ◽  
Vol 53 (2) ◽  
Author(s):  
Amir Hussain ◽  
Muhammad Zafar ◽  
Shehla Shinwari ◽  
Zabta Khan Shinwari ◽  
Mushtaq Ahmad ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Herbal Drugs

Traditional Herbal Medicines, Newer Herbs and Other Novel Approaches Integrated in Herbal Medicine for Atopic Dermatitis-A Narrative Review

2020 ◽  
Vol 15 (3) ◽  
pp. 194-208
Author(s):  
Pravin Kumar ◽  
Dinesh Kumar Sharma ◽  
Mahendra Singh Ashawat
Keyword(s):  
Atopic Dermatitis ◽  
Herbal Medicines ◽  
Developed Countries ◽  
Skin Lesions ◽  
Scientific Data ◽  
Herbal Drugs ◽  
Biological Drugs ◽  
Alternative Treatment Option

Atopic Dermatitis (AD) is a prolonged reverting skin ailment with characteristically distributed skin lesions. In the previous decades, researchers had shown a marked interest in AD due to its increased prevalence in developed countries. Although different strategies including biological and immune modulators are available for the treatment of AD, each has certain limitations. The researchers had shown considerable interest in the management of AD with herbal medicines. The establishment of herbal drugs for AD might eliminate local as well as systemic adverse effects associated with long term use of corticosteroids and also higher cost of therapy with biological drugs. The present review discusses the traditional East Asian herbal medicines and scientific data related to newer herbal extracts or compositions for the treatment of AD. In vivo animal models and in vitro cell cultures, investigated with herbal medicines to establish a possible role in AD treatment, have also been discussed in the paper. The paper also highlights the role of certain new approaches, i.e. pharmacopuncture, a combination of allopathic and herbal medicines; and novel carriers (liposomes, cubosomes) for herbal drugs on atopic skin. In conclusion, herbal medicines can be a better and safe, complementary and alternative treatment option for AD.

Potential Antiulcer Agents From Plants: A Comprehensive Review

2019 ◽  
Vol 5 (3) ◽  
pp. 170-231
Author(s):  
Minky Mukhija ◽  
Bhuwan Chandra Joshi
Keyword(s):  
Medicinal Plants ◽  
Developed Countries ◽  
Scientific Data ◽  
Antiulcer Activity ◽  
Peptic Ulcers ◽  
Comprehensive Review ◽  
Chemical Structures ◽  
Mucosal Thickness

Background: Peptic ulcer is a deep gastrointestinal erosion disorder that involves the entire mucosal thickness and can even penetrate the muscular mucosa. Nowadays, several plants and compounds derived from it have been screened for their antiulcer activity. In the last few years, there has been an exponential growth in the field of herbal medicine. This field has gained popularity in both developing and developed countries because of their natural origin and less side effects. Objective: This review aims to provide a comprehensive summary of currently available knowledge of medicinal plants and phytoconstituents reported for their anti-ulcer properties. Methods: The worldwide accepted database like SCOPUS, PUBMED, SCIELO, NISCAIR, ScienceDirect, Springerlink, Web of Science, Wiley, SciFinder and Google Scholar were used to retrieve available published literature. Results: A comprehensive review of the present paper is an attempt to list the plants with antiulcer activity. The review narrates the dire need to explore potential chemical moieties that exert an antiulcer effect, from unexploited traditional plants. Furthermore, the present study reveals the intense requirement to exploit the exact mechanism through which either the plant extracts or their active constituents exhibit their antiulcer properties. Conclusion: This article is the compilation of the plants and its constituents reported for the treatment of peptic ulcers. The Comprehensive data will surely attract the number of investigators to initiate further research that might lead to the drugs for the treatment of ulcers. As sufficient scientific data is not available on plants, most of the herbals cannot be recommended for the treatment of diseases. This can be achieved by research on pure chemical structures derived from plants or to prepare new lead compounds with proven beneficial preclinical in vitro and in vivo effects. However, a lot remains to be done in further investigations for the better status of medicinal plants.

scholarly journals Medicinal Plants, Phytochemicals, and Herbs to Combat Viral Pathogens Including SARS-CoV-2

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1775
Author(s):  
Arumugam Vijaya Anand ◽  
Balasubramanian Balamuralikrishnan ◽  
Mohandass Kaviya ◽  
Kathirvel Bharathi ◽  
Aluru Parithathvi ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Severe Acute Respiratory Syndrome ◽  
Viral Entry ◽  
Antiviral Agents ◽  
Special Focus ◽  
Direct Inhibition ◽  
Viral Pathogens ◽  
Important Health ◽  
Antiviral Activities ◽  
Important Health Issue

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome corona virus-2 (SARS-CoV-2), is the most important health issue, internationally. With no specific and effective antiviral therapy for COVID-19, new or repurposed antiviral are urgently needed. Phytochemicals pose a ray of hope for human health during this pandemic, and a great deal of research is concentrated on it. Phytochemicals have been used as antiviral agents against several viruses since they could inhibit several viruses via different mechanisms of direct inhibition either at the viral entry point or the replication stages and via immunomodulation potentials. Recent evidence also suggests that some plants and its components have shown promising antiviral properties against SARS-CoV-2. This review summarizes certain phytochemical agents along with their mode of actions and potential antiviral activities against important viral pathogens. A special focus has been given on medicinal plants and their extracts as well as herbs which have shown promising results to combat SARS-CoV-2 infection and can be useful in treating patients with COVID-19 as alternatives for treatment under phytotherapy approaches during this devastating pandemic situation.

scholarly journals Novel activities of safe-in-human broad-spectrum antiviral agents

2018 ◽  
Vol 154 ◽  
pp. 174-182 ◽  
Author(s):  
Aleksandr Ianevski ◽  
Eva Zusinaite ◽  
Suvi Kuivanen ◽  
Mårten Strand ◽  
Hilde Lysvand ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Antiviral Agents

Ethnobotanical survey of an -diabe c plants applied in West of Algeria

2019 ◽  
Vol 8 (2) ◽  
pp. 57-62
Author(s):  
W Kouadri Boudjelthia ◽  
K Hammadi ◽  
M Kouidri ◽  
A Noui ◽  
N Djebli
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicine ◽  
Data Base ◽  
Broad Spectrum ◽  
Western Region ◽  
Ethnobotanical Survey ◽  
Valuable Data ◽  
Berberis Vulgaris ◽  
Aerial Parts ◽  
Set Up

This study was carried out in order to set up an inventory list of medicinal plants used in traditional medicine to treat diabetes for which an ethnobotanical test was carried out on 670 diabe c subjects in the Western region of Algeria (Chlef, Mostaganem, Mascara, Oran, Sidi-bel-Abbes, Saida and Tiaret) using a survey. 24 an hyperglycemic medicinal plants were listed of which Berberis vulgaris, Zygophyllum geslini, Erythraea centaurium and Olea eu- ropea represented a broad spectrum of use. Likewise, the an hyperglycemic recipes were prepared mainly in decoc on (45.37%) and infusion (39.62%), and from leaves (42%) and aerial parts (16%). A very valuable data base has been reported for further research, especially for some elds such as phytochemistry and phytopharmacology that aim to identify new natural principles.

scholarly journals Antiepileptic and Antioxidant Activity of Some Medicinal Plants: A Review

2017 ◽  
Vol 9 (10) ◽  
Author(s):  
Jeenu Joseph ◽  
Lincy Joseph ◽  
Mathew George
Keyword(s):  
Medicinal Plants ◽  
Cell Activity ◽  
Acorus Calamus ◽  
Herbal Drugs ◽  
Clinical Testing ◽  
Bacopa Monniera ◽  
Ficus Religiosa ◽  
Antiepileptic Agents

Medicinal plants are the oldest form of healthcare known to mankind. Antioxidants are considered to be important in fighting against the damages done by the free radicals produced due to oxidative stress. Antiepileptic drugs help to minimize or to irradiate the convulsive shocks and seizures as a result of abnormal and excessive nerve cell activity. Standardized, well established in vitro and in vivo methods are available for experimental evaluation of antioxidant and antiepileptic agents. A step wise procedure from in vitro and in vivo seems reasonable to reduce the large quantity of potential drugs to a few promising agents for further clinical testing. This review has focused on some herbal drugs with both antioxidant and antiepileptic property such as Brassica nigra, Bacopa monniera, Ficus religiosa, Convolvulus pluricalis, Jatamansi and Acorus calamus.

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