Pharmacokinetic and analgesic properties of the injectable dosage form of a new imidazobenzimidazole derivative RU-1205 with kappa agonist activity
2015 ◽
Vol 61
(5)
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pp. 636-639
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Keyword(s):
Pharmacokinetic properties of imidazobenzimidazole derivative compound RU-1205 were investigated after subcutaneous administration to rabbits as a substance and a dosage form (lyophilisates for injection) at a dose of 25 mg/kg. The lyophilisate was characterized by high values of the relative bioavailability. In tests, the “hot plate” and “vinegar cramps” the dosage form and the substance exhibited the same analgesic effect.
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2018 ◽
Vol 11
(1)
◽
pp. 328
Keyword(s):
2018 ◽
Vol 3
(2)
◽
pp. 13
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Keyword(s):
2021 ◽
pp. 153-164
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2020 ◽
pp. 10-22
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2017 ◽
Vol 11
(7)
◽
pp. 1056-1060
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