scholarly journals Recreational Activities and d-Amphetamine Effects in High and Low Sensation Seekers

2021 ◽  
Vol 9 (8) ◽  
Author(s):  
Thomas Kelly ◽  
Jennifer Klebaur ◽  
Andrea Perry ◽  
Catherine Martin ◽  
Donald Lynam ◽  
...  

This study examined the behavioral effects of d-amphetamine and recreational activities, alone and in combination, in high and low impulsive sensation seekers. Healthy 18-27 year-old participants, scoring in the upper (N=8) or lower (N=8) third of college students on the impulsive sensation-seeking scale of the Zuckerman-Kuhlman Personality Questionnaire, completed eight test days in which sessions were completed before (i.e., baseline) and 60, 120 and 180 minutes after d-amphetamine (0, 10 mg/70 kg) administration. Between sessions, subjects completed recreational activities (movies, music, reading, videogames) identified as high or low in sensation value. Each of four conditions (low and high sensation value activities combined with placebo and active drug) was administered under double-blind conditions on 2 days according to a randomized-block design. Typical stimulant-like cardiovascular and task performance effects were engendered by d-amphetamine; consistent with previous research, the magnitude of drug effects were greater among high sensation seekers. High sensation value activities engendered independent stimulant-like effects on subject ratings. These results suggest that d-amphetamine and high sensation stimulus materials may activate a common neurobiological substrate, likely the mesolimbic dopamine system, and that individual differences in sensation seeking status play a role in vulnerability to stimulant drug abuse.

PEDIATRICS ◽  
1983 ◽  
Vol 71 (1) ◽  
pp. 13-18 ◽  
Author(s):  
Asher Tal ◽  
Chanan Bavilski ◽  
David Yohai ◽  
Jacob E. Bearman ◽  
Rafael Gorodischer ◽  
...  

Thirty-two infants, aged 1 to 12 months, hospitalized with acute wheezing, were studied. They were randomly divided into four treatment groups of eight patients each. The treatments were intramuscular dexamethasone or placebo (double-blind), and salbutamol (oral and inhaled), or none (open), in all four possible combinations. The study was carried out as a randomized block design with eight blocks of four infants each, matched by age and clinical score. Average daily improvements, as reflected by changes in the clinical score and length of hospital stay, was essentially the same for infants treated with placebo, salbutamol alone, and dexamethasone alone. However, combined salbutamol-dexamethasone treatment resulted in more than twice the rate of improvement of the other treatments. The difference was statistically highly significant (P < .01). Furthermore, the response of this combined treatment was observed within 24 hours; none of the ten infants in whom there was no significant improvement within 48 hours and neither of the two patients who developed respiratory failure received the combined salbutamol-dexamethasone treatment. A potentiating effect of corticosteroids on the β-adrenergic responsiveness is a possible explanation for the advantage of this combined treatment in the management of acute wheezing in infancy.


Author(s):  
André Beauducel ◽  
Burkhard Brocke ◽  
Alexander Strobel ◽  
Anja Strobel

Abstract: Zuckerman postulated a biopsychological multilevel theory of Sensation Seeking, which is part of a more complex multi-trait theory, the Alternative Five. The Sensation Seeking Scale Form V (SSS V) was developed for the measurement of Sensation Seeking. The process of validation of Sensation Seeking as part of a multilevel theory includes analyses of relations within and between several levels of measurement. The present study investigates validity and basic psychometric properties of a German version of the SSS V in a broader context of psychometric traits. - The 120 participants were mainly students. They completed the SSS V, the Venturesomeness- and Impulsiveness-Scales of the IVE, the BIS/BAS-Scales, the ZKPQ and the NEO-FFI. - The results reveal acceptable psychometric properties for the SSS V but with limitations with regard to factor structure. Indications for criterion validity were obtained by prediction of substance use by the subscales Dis and BS. The results of a MTMM analysis, especially the convergent validities of the SSS V were quite satisfying. On the whole, the results yielded sufficient support for the validity of the Sensation Seeking construct or the instrument respectively. They also point to desirable modifications.


2009 ◽  
Vol 23 (3) ◽  
pp. 104-112 ◽  
Author(s):  
Stefan Duschek ◽  
Heike Heiss ◽  
Boriana Buechner ◽  
Rainer Schandry

Recent studies have revealed evidence for increased pain sensitivity in individuals with chronically low blood pressure. The present trial explored whether pain sensitivity can be reduced by pharmacological elevation of blood pressure. Effects of the sympathomimetic midodrine on threshold and tolerance to heat pain were examined in 52 hypotensive persons (mean blood pressure 96/61 mmHg) based on a randomized, placebo-controlled, double-blind design. Heat stimuli were applied to the forearm via a contact thermode. Confounding of drug effects on pain perception with changes in skin temperature, temperature sensitivity, and mood were statistically controlled for. Compared to placebo, higher pain threshold and tolerance, increased blood pressure, as well as reduced heart rate were observed under the sympathomimetic condition. Increases in systolic blood pressure between points of measurement correlated positively with increases in pain threshold and tolerance, and decreases in heart rate were associated with increases in pain threshold. The findings underline the causal role of hypotension in the augmented pain sensitivity related to this condition. Pain reduction as a function of heart rate decrease suggests involvement of a baroreceptor-related mechanism in the pain attrition. The increased proneness of persons with chronic hypotension toward clinical pain is discussed.


2012 ◽  
Vol 28 (1) ◽  
pp. 11-18 ◽  
Author(s):  
Marcus Roth ◽  
Philipp Hammelstein

Based on the conception of sensation seeking as a need rather than a temperamental trait ( Hammelstein, 2004 ), we present a new assessment method, the Need Inventory of Sensation Seeking (NISS), which is considered to assess a motivational disposition. Three studies are presented: The first examined the factorial structure and the reliability of the German versions of the NISS; the second study compared the German and the English versions of the NISS; and finally, the validity of the NISS was examined in a nonclinical study and compared to the validity of conventional methods of assessing sensation seeking (Sensation Seeking Scale – Form V; SSS-V). Compared to the SSS-V, the NISS shows better reliability and validity in addition to providing new research possibilities including application in experimental areas.


2010 ◽  
Author(s):  
James D. Sargent ◽  
Susanne Tanski ◽  
Mike Stoolmiller ◽  
Reiner Hanewinkel

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Rika Agustina ◽  
Rita Sunartaty ◽  
Teuku Makmur

Coconut frond ash is one of the wastes from coconut trees which has not been maximally utilized. Coconut frond ash contains MgCl2 and KCl so that it can be used as a salt substitute in the process of preserving fish. In this study coconut frond ash was used as a basic ingredient for making dried mackerel with a long time of drying to storage. The purpose of this study was to determine the effect of drying time on mackerel storage. The research design used was a Randomized Block Design (RCBD) with 2 factors studied. The first factor is the drying time consists of 3 levels, namely P1 = 3 days, P2 = 4 days, P3 = 5 days. The second factor is storage which consists of 3 levels, namely S1 = 30 days, S2 = 60 days, S3 = 90 days. Each treatment was repeated 2 times to obtain 18 experimental units to observed hedonic tests. From the results of the study it can be stated that the treatment has a very significant effect (P≥0.01) on the hedonic test which includes (color, aroma, taste and texture).


2019 ◽  
Vol 6 (1) ◽  
pp. 78
Author(s):  
Muhammad Ade Salim ◽  
Muhammad Nur Ihsan ◽  
Nur Isnaini ◽  
Trinil Susilawati

ABSTRAKAir kelapa muda varietas viridisdapat dijadikan pengencer aletrnatif semen cair bagi program IB di daerah minim sarana semen beku. Tujuan penelitian ini untuk menguji pengaruh penggunaan air kelapa muda viridissebagai bahan pengencer terhadap kualitas semen cair kambing Boer setelah didinginkan. Dilaksanakanselama 3 bulan di Laboratorium Fakultas Peternakan UBUnit SumberSekar,Malang. Metodenya yaitu eksperimen. Semen dari  3 pejantan Boer umur 3-5 tahun, dikoleksi seminggu sekali dengan VB. Air kelapa mudaviridis umur 5-7 bulan serta tris aminomethane sebagai kontrol. Didesain menggunakan Rancangan Acak Kelompok (RAK) dengan 2 perlakuan yaitu P0 (tris aminomethane + 10% KT) dan  P1 (air kelapa muda viridis + 10% KT) masing-masing diulang 10 kali. Data dianalisis dengan analisis Ragam (Anova) dengan software Genstat 18. Variabelnya yaitu motilitas individu, viabilitas dan abnormalitas. Hasil penelitian yaitu motilitas individu pada P1bertahan sampai 4 hari (40,5± 24,3%), viabilitas terbaik sampai hari ke-5 (42±24,6%), abnormalitas terendah di hari ke-7(1,31± 0,6). Kesimpulannya, Pengencer air kelapa muda viridis dapat mempertahankan kualitas semen cair kambing Boer selama 4 hari untuk motilitas dan 5 hari untuk viabilitas.Kata Kunci:pengencer, air kelapa, varietas viridisABSTRACTYoung viridis coconut water could be used as an alternative to liquid semen diluent for artificial insemination program in the area with limited facility for frozen semen production. This study evaluated the use of young coconut water as a diluent on liquid semen quality of Boer goat after cold storage. This study was carried out for 3 months at Sumber Sekar Laboratory, Faculty of Animal Husbandry, University of Brawijaya, Malang. The semen was collected from 3 Boer bucks aged at 3 to 5 years old. The semen collection was done once a week with the aid of artificial vagina. The diluents used were young Viridis coconut (5 to 7 months old) and tris aminomethane. The method used was an experiment in a randomized block design with 2 treatments and 10 replicates. The treatments used were T0: tris aminomethane + 10% egg yolk (control) and T1:  young Viridis coconut water + 10% egg yolk. Data were analyzed by analysis of variance using Genstat 18 software. The variables measured were sperm individual motility, viability, and abnormality. The results showed that the sperm individual motility in T1 survived up to 4 days (40.5± 24.3%), the best viability at 5 days (42.0±24.6%),  while the lowest abnormality at 7 days (1.31±0.6). It could be concluded that: 1. Tris aminomethane diluent has higher quality with the storage length up to 9 days, 2. Young Viridis coconut water diluent could preserve liquid semen quality of Boer goat up to 4 days for sperm motility and 5 days for sperm viability.Keywords: diluents, coconut water, viridis variety


2011 ◽  
Vol 59 (1) ◽  
pp. 87-102 ◽  
Author(s):  
S. Sood ◽  
N. Kalia ◽  
S. Bhateria

Combining ability and heterosis were calculated for fourteen lines of linseed in a line × tester mating design using twelve lines and two diverse testers in two different environments. The hybrids and parental lines were raised in a completely randomized block design with three replications to investigate seed and fibre yield and their component traits. Genetic variation was significant for most of the traits over environments. Combining ability studies revealed that the lines KL-221 and LCK-9826 were good general combiners for seed yield and most of its components, whereas LMH-62 and LC-2323 were good general combiners for yield components only. Moreover, KL-221 was also a good general combiner for fibre yield. Similarly, B-509 and Ariane were good general combiners for fibre yield and most of its components. Among the specific cross combinations, B-509 × Flak-1 was outstanding for seed yield per plant and B-509 × KL-187 and LC-2323 × LCK-9826 for fibre yield per plant, with high SCA effects. In general, the hybrids excelled their respective parents and the standard checks for most of the characters studied. Based on the comparison of mean performance, SCA effects and the extent of heterosis, the hybrids LC-2323 × LCK-9826 and B-509 × KL-221 appeared to be the most promising for both seed and fibre yield. Other promising combinations were LC-2323 × KL-210 and B-509 × Ariane for seed and fibre yield, respectively. The superiority of LC-2323, LCK-9826, KL-221, B-509 and Ariane as good general combiners was further confirmed by the involvement of these parents in the desirable cross combinations.


2016 ◽  
Vol 5 (2) ◽  
pp. 277
Author(s):  
Usman Usman ◽  
Neltje Nobertine Palinggi ◽  
Kamaruddin Kamaruddin ◽  
Makmur Makmur ◽  
Rachmansyah Rachmansyah

Penelitian ini dilakukan untuk mendapatkan informasi tentang kebutuhan optimum kadar protein dan lemak pakan terhadap pertumbuhan dan komposisi badan ikan kerapu macan ukuran konsumsi. Sembilan pakan uji dibuat dalam bentuk moist pelet dengan tiga dosis protein (46%, 49%, dan 52%) dan tiga dosis lemak (9%, 11%, dan 13%). Ikan uji dipelihara dalam 27 keramba jaring apung ukuran 1 m x 1 m x 2 m selama 140 hari, diberi pakan uji secara satiasi dua kali sehari dan diset dalam rancangan acak kelompok pola faktorial berdasarkan kelompok ukuran bobot awal ikan yaitu (i) 122,0±4,2 g; (ii) 144,0±7,1 g; dan (iii) 172,9±10,5 g. Hasil penelitian menunjukkan bahwa laju pertumbuhan spesifik dan sintasan ikan relatif sama (>0,05) di antara perlakuan. Efisiensi pakan cenderung meningkat dengan meningkatnya kadar protein dan lemak pakan. Tingkat efisiensi pemanfaatan protein cenderung menurun dengan meningkatnya kadar protein pakan, tetapi meningkat dengan meningkatnya kadar lemak pakan. Hasil analisis proksimat badan ikan menunjukkan bahwa kadar bahan kering dan lemak ikan relatif tidak dipengaruhi (P>0,05) oleh peningkatan kadar protein pakan, namun kadar bahan kering dan lemak ikan tersebut sedikit naik dengan meningkatnya kadar lemak pakan. Kadar protein dan abu ikan relatif tidak dipengaruhi oleh perubahan kadar protein dan lemak pakan. Berdasarkan hasil penelitian ini tampak bahwa pakan dengan kadar protein 49% dan lemak sekitar 11% mampu memberikan pertumbuhan dan komposisi badan ikan kerapu macan yang baik.This experiment was conducted to investigate the optimum dietary protein and lipid level for growth and body composition of tiger grouper. Nine dietary experiments were formulated to moist pellet contain three levels of protein (46%, 49%, and 52%) and three levels of lipid (9%, 11%, and 13%). The fish were fed twice daily to satiation for 140 days in twenty seven net cages of 1 m x 1 m x 2 m, were set up factorial randomized block design based on fish size group i.e. (i) 122.0±4.2 g, (ii) 144.0±7.1 g, and (iii) 172.9±10.5 g. The results shown that specific growth rate and survival rate were not significant different (P>0.05) for all treatments. Feed efficiency increased when protein and lipid content increased. Protein efficiency decreased when protein diets increased and increased when lipid diets increased. No interaction occurred between protein and lipid content to all observable biological variables. Dry matter and lipid content of test fish were not affected by protein diets increase but by lipid diet content. Protein and ash of test fish were not affected by either protein or lipid contained in diet. To assure high growth rates and high quality of fish product, it is suggested to feed tiger grouper with diet containing 49% protein and 11% lipid. 


Author(s):  
Nihad H. Mutlag ◽  
Ameer S. A. Al-Haddad

A field study was conducted to evaluate the efficiency of four microbial insecticides viz. Beauveria bassiana; HaNPV (Helicoverpa armigera Nuclear Polyhedrosis virus); (Bacillus thuringiensisvar.kurstaki 2 gm/L); HaNPV+Bt; neem oil; neem cake and D.D.V.P EC 76% @0.05% at Research Farm SHIATS,Allahabad during rabi season of 2011-2012. The experiment was laid out in randomized block design with seven treatment and replicated thrice. The observation larval populations of H. armigera were recorded one day before treatment was recorded at 3,7, and 10 days after treatments. The larva population of H. armigera appeared in the third week of February (8 the Standard week) and reached its peak of 14.65 larvae in first week of April and decline rapidly with maturation of crop. There was only one peak in the larval population observation in the 1st week. Bacillus thuringiensis was the most effective chemical by D.D.V.P.76%@0.05% . Among the microbial insecticides. HaNPV ,was the most effective followed by HaNPV+Bt and neem cake . The combination treatments were less effective than the individual treatment neem oil and B. bassiana were the least effective treatment in reducing the larval population of Heliverpa armigera.


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