scholarly journals Drug utilisation and self medication pattern of anti-fungal drugs in dermatology outpatient department of a tertiary care hospital

Author(s):  
Pooja Deb ◽  
Ipseeta Mohanty ◽  
Indu Slathia ◽  
Vandana Verma

Background: Fungal infections have become increasingly prevalent. Self-medication is a common health care practice to treat fungal diseases or for symptomatic relief. Because of self-medication drug-sensitive fungal pathogens have gradually developed resistance. Aims and objectives of the study was to define the pattern of antifungal drug use and self-medication pattern for common fungal infections of skin in dermatology outpatient.Methods: The present study was an Observational, descriptive, cross sectional study conducted at Dermatology OPD of MGM Medical College, Kamothe. All adult patients with fungal infections of the skin attending the Dermatology OPD were enrolled. A study performa was specifically designed to record information related to demographic, disease profile and medications prescribed.Results: A total of 200 patient’s prescriptions were analysed. Percentage of drugs prescribed by generic name was found to be 20.26%, Percentage of drugs prescribed from National Essential Drug List 2015 was found to be 79.74%. There were no encounters with antibiotic and parenteral preparations. Only 5.16% of the drugs prescribed were fixed dose combination (FDC) as compared to 94.93% as Monotherapy. Most frequently prescribed anti-fungal agents were the azoles; amongst which Imidazoles (53.33%) were the commonest. Most commonly prescribed individual antifungal was oral Terbinafine (64.81%) and topical was Eberconazole (58.49%). The dosage form most frequently encountered was Cream (92.45%). The prevalence of self-medication for dermatological conditions among patients was 62.26%. Most of the drugs for self-medication were topical (creams) FDC of antifungal and steroids. Around 78% of the self-medication information was obtained from the chemists.Conclusions: The study documented physician preference for Monotherapy than FDC. Prescribers need to be made aware for prescribing generic and essential drugs, thus ensuring rational utilization. They also need to counsel and discourage patients from self-medication.

2020 ◽  
Vol 58 (232) ◽  
Author(s):  
Aashish Kumar Bhattarai ◽  
Anna Acharya ◽  
Prabin Kumar Karki

Introduction: Lipids contribute to atherosclerosis and obesity that can lead to different cardiovascular diseases. Statins are hydroxymethylglutaryl reductase inhibitors that effectively lower the cholesterol level. It is widely prescribed in the treatment of hypercholesterolemia. Thus it optimizes the lipoprotein profile. The selection of a particular drug by the practitioner should be primarily based on clinical outcome. This study was conducted to find the type of statins that are most preferred by the doctors for treating dyslipidemia and preferred the fixed-dose in a tertiary care hospital. Methods: This was a descriptive cross-sectional study conducted among the practicing doctors of Kathmandu Medical College from July to August 2020. Ethical approval was taken from the Institutional Review Committee of the college (Ref: 207202006). Convenient sampling was done. A semi-structured questionnaire was used with consent. The data were analyzed with Social Statistical Package for the Social Sciences version 20. Results: Statins, with the score 4.25 was accounted for most preferred for the treatment of dyslipidemia. Among different statins, atorvastatin with a score of 4.48 was most popular followed by rosuvastatin 2.9 score and simvastatin 2.1 scores. Conclusions: Statins were the most preferred agents for the treatment of dyslipidemia. Although different types of statins ought to have similar efficacy in treating dyslipidemia, atorvastatin was found to be popular and the most commonly prescribed one. The most common side effect reported with statins was myopathy.


2021 ◽  
pp. 191-194
Author(s):  
Kishore M S ◽  
Narendra Kumar ◽  
S Sindhu

Background: The expanding and challenging eld of psychopharmacology is constantly seeking new and improved drugs to treat psychiatric disorders. Psychotropic drugs utilization in actual clinical practice, effectiveness and safety in the real-life situation needs continuous study. Therefore, the study was undertaken to analyze the prescription pattern of psychotropic drugs. Methods: A Cross sectional study was conducted in the psychiatry out-patient department of a tertiary care hospital for 4 months. Diagnosis was made according to ICD-10 criteria. Prescription pattern was analyzed using World Health Organization (WHO) drug indicators. Results: Psychotropic drugs constituted 74.85% of the prescribed medication. Average number of the psychotropic drugs per prescription was 2.53. Percentage of prescriptions with injectable drugs accounted for 5.13%. 59.28% of the drugs were prescribed by generic names, while the rest were branded. 28% of prescriptions contained psychotropic FDCs (Fixed dose th combination). 78.65% of the drugs were from the WHO's 18 List of Essential Medicines. Among the total psychotropic drugs prescribed, antipsychotics (43.87%) were the most commonly prescribed class of drugs followed by antidepressants (23.32%), anxiolytics (22.13%) and the mood stabilizers (9.88%) were the least. Conclusions: Prescription pattern of the psychotropic drugs were in accordance to the recommendations of various treatment guidelines. Antipsychotics were the most commonly prescribed psychotropic drugs.


Author(s):  
Sarang A Deshmukh ◽  
Yashasvi Agarwal ◽  
Harshita Hiran ◽  
Uma Bhosale

 Objective: The objective of the study was to evaluate antimicrobial prescription pattern in outpatient departments.Method: This was a prospective, cross-sectional and observational study over 12 weeks total 400 prescriptions of either gender and age; containing antimicrobial agents (AMAs) were analyzed for demographic data and the WHO prescribing indicators.Results: Most of prescription were given to men (n=262). The most common group of AMA used was Cephalosporins (n=141, 35.25%); of which Ceftriaxone was most commonly prescribed (n=73, 18.25%). 10 AMAs were from the WHO essential medicine list AMAs. Men outnumbered women in prescribing antibiotics (n=262 vs. 138). Most of AMAs receivers were between 26 and 35 years (n=128, 32%). Amoxicillin+Clavulanic acid fixed-dose combination was most common (n=84, 21%). Most of the prescriptions were containing four drugs per prescriptions (n=130, 32.5%). Only 10% of the prescription was given by generic name and rest 90% were given by brand name. Oral dosage form of AMAs was predominant (n=340, 85%). Vitamins and supplement were most common comedication received by patients.Conclusion: Antibiotic use was found to be reasonable and rational in most of the cases. However, still, prescribers should improve prescribing practices and make it more rational.


2014 ◽  
Vol 52 (8) ◽  
pp. 810-818 ◽  
Author(s):  
Kiatichai Faksri ◽  
Wanlop Kaewkes ◽  
Kunyaluk Chaicumpar ◽  
Prajuab Chaimanee ◽  
Suwin Wongwajana

Author(s):  
Shyam Govind Rathoriya ◽  
Ankit Kumar Jain ◽  
Kavita A. Shinde

<p class="abstract"><strong>Background:</strong> Dermatophytoses are the infection of keratinized tissues such as the epidermis, hair, and nails caused by a group of closely related filamentous fungi known as dermatophytes.</p><p class="abstract"><strong>Methods:</strong> It was a hospital based cross-sectional study. A total number of 150 clinically diagnosed cases of skin, hair and nail infections were randomly selected from all the age groups and of both the sexes, attending Dermatology Outpatient department of CMCH, Bhopal from January 2016-December 2017.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of total 150 subjects, most common clinical type of dermatophytosis, identified in our study, was tinea corporis in 53 (35.3%) subjects followed by tinea cruris in 34 (22.6%) subjects. 134 (89.3%) subjects were tested positive by direct microscopy (KOH mount) and 69 (46.0%) by culture. Highest KOH mount positivity was seen in patient suffering from tinea corporis (94.3%) followed by tinea cruris (94.1%). Culture positivity was highest with tinea corporis (54.7%) followed by tinea lesions on more than one site (47.3%) and tinea cruris (47.0%). In our study, total 69 culture positive samples were isolated and the most common species isolated was T. rubrum in 41 (59.42%) cases.</p><p><strong>Conclusions:</strong> The present study gives valuable insight regarding clinical and mycological pattern of superficial fungal infections in this region as well as shows the importance of mycological examination of dermatophytosis samples for planning effective management. </p>


Author(s):  
Madhulika Johnson ◽  
Dinesh Kumar Badyal

Background: Self-medication is practiced universally. Having medical knowledge plays a vital role in its prevalence. It is more prevalent in higher education course students especially medical students. However, it is increasing in dental and paramedical students. Hence, this study was conducted to evaluate self-medication among medical, dental and para-medical students in a tertiary care hospital.Methods: A cross sectional questionnaire based study was conducted among 449 undergraduate students. They were divided into three groups. A questionnaire was developed based on literature. The questionnaire was validated and finalised. The paper questionnaire was administered to students. The data collected from questionnaires was analysed. The results were expressed as percentages and frequencies.Results: The male female ratio of students who filled questionnaire was 65:35. All the students (100%) reported that they practice self-medication. The most common reason for self-medication was prior experience (36%) in group A as well as in group B (46%), but in group C, 39% mentioned no serious problem. Main information source was family members in all the groups (A 57%, B 53%, C 29%) followed by advice from senior/friends. Fever was most common symptom reported (29%) by group A followed headache (28%) in group C and cough and cold (23%) in group B. The commonest group of drugs used is cough syrups (25%) in group B, followed by analgesics (23%) in group C and antipyretics (21%) in group A.Conclusions: Self-medication is growing among dental and paramedical students too. It is necessary to educate them about self-medication to prevent future disastrous consequences as well as to make them aware of appropriate use of self-medication.


Author(s):  
Nitant Trivedi ◽  
Hemangini R. Acharya ◽  
Manish J. Barvaliya ◽  
C. B. Tripathi

Background: Objective of the study was to evaluate the prescribing pattern in patients of asthma visiting outpatient departments.Methods: Collected prescriptions were analyzed for demographic variables, proportions of various comorbid conditions, average number of drugs per prescription, average number of anti-asthmatic drugs per prescription, proportion of prescription with antibiotics, fixed dose combinations, and generic/brand names, proportion of formulations utilized, proportion of concomitant medications and possible drug interactions, average cost per prescription, average cost of antiasthmatic drugs per prescription, proportion of irrational prescription and adverse drug reactions.Results: Total 139 prescriptions were evaluated. Deriphyllin was the most commonly prescribed anti-asthmatic drug followed by beta agonist- steroid combination. Majority drugs were prescribed by inhalational route. Deriphyllin, and dexamethasone were prescribed by oral route and salbutamol was by both oral and inhalational route of administration. Antibiotics were prescribed to 24 patients. Possible drug interaction with deriphyllin was found in 15 prescriptions. Average cost per prescription was Rs. 193.4 (95%CI: 171.6-215.3).Conclusions: Prescribing pattern of asthma in our hospital shows more use of anti-asthmatic drugs. Standard treatment guideline should be followed. Role of methylxanthine in long term management of asthma should be justified.


Author(s):  
Ranjodh Jeet Singh ◽  
Kanika Kohli

Background: Self-medication is defined as selection and use of medicines by individuals to treat self-recognized or self-diagnosed conditions or symptoms. Self-medication can lead to various health problems like adverse drug reactions, prolonged suffering, and drug-dependence and increase resistance among various pathogens. Very few studies have evaluated its pattern and prevalence in physiotherapy students. Material and Methods: Study setting: A cross-sectional questionnaire-based study was conducted on the second year MBBS students of Maharishi Markandeshwar institute of Medical sciences and research collaborated with a tertiary care hospital in North India. Study design: A questionnaire consisting of open and close ended questions related to various aspects of self-medication was distributed to the students. An informed consent was given to them and only the students, who gave consent, anonymously filled the questionnaire and participated in this present study. Results: A total of 104 students, two incomplete questionnaires were excluded and remaining 102 were analyzed. The most common ailment for seeking self-medication was common cold and cough (44.11%), sore throat (24.50%), fever (12.74%), pain abdomen, heartburn, diarrhoea, menstrual cramps, gynecological infections (18.62%) are the main factors attributed to predominant ailment which leads them to self medicate. The commonly/frequently used drugs or combination drug therapy included were antipyretics including paracetamol (32.35%), NSAIDs including aspirin(23.52%), antibiotics including antimicrobials(15.68%), Antihistaminics (9.5%), Antifungals including topical ointments/lotions(10.78%%), and other miscellaneous accounting for 7.84%.According to our documented results cost effectiveness (65.68%) has emerged as the prominent reason for self medication, followed by time saving (13.72%), further ease (12.74%) for reaching the drug/medicine as considered by participants as the valid point through pharmacy or leftovers. and last but not least learning opportunities (07.84%) were also accounting as the interesting reason for this pattern of self medication. Conclusions: Our study concludes that self-medication pattern is widely practiced among second year MBBS students of this institute. As the pattern of self medication is very high as documented in this study thus, there is affirm need to make them aware about the advantages and disadvantages of self-medication in order to ensure optimistic usage of pattern of self medication with reduced errors and wholesome advantages.


Author(s):  
Kauser Jabeen ◽  
Muneeb Khan ◽  
Seema Umar ◽  
Najma Shaheen ◽  
Joveria Farooqi

Abstract Burn patients are at great risk of developing fungal wound infections. Fungi are frequently cultured from burn tissue specimens alone or in combination with bacteria. However, the spectrum of fungi in burn patients from Pakistan has not been reported previously. A retrospective laboratory-based study was conducted and data on all positive cultures from burn wounds were included. During the study period, specimens were cultured on appropriate media and incubated for anaerobic and aerobic growth. Clinical and demographic information recorded during clinical reporting was also collected. Seventy tissue cultures were positive for microorganisms. Of these, 27 (39%) had growth of either filamentous mold (17 cases) or Candida species (14 cases). Two cases had growth of both mold and yeast. Aspergillus flavus was the most common mold (9) followed by Fusarium species (3). Candida tropicalis was the most common yeast (7) followed by Candida parapsilosis (4). There was concomitant bacterial growth in 19 cases, predominantly of Staphylococcus aureus (13), Pseudomonas aeruginosa (8), and other Gram-negative rods (6). Of the 35 patients in which treatment history was available, 33 were receiving broad-spectrum antibiotics. A high incidence of fungal isolation was seen in this study. Their findings are consistent with the global increase in fungal infections in burn wounds. High index of suspicion by clinicians and revision of culture protocols in burn patients may be warranted for optimal patient management.


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