scholarly journals Study of drug utilization and antimicrobial prescription pattern of indoor paediatrics cases in tertiary care hospital

2017 ◽  
Vol 7 (1) ◽  
pp. 98
Author(s):  
Vivek Virbhan Bamel ◽  
Savita Ramesh Shahani ◽  
Nimain C. Mohanty
Keyword(s):  
Drug Utilization ◽  
Tertiary Care ◽  
Systemic Steroid ◽  
Care Hospital ◽  
Prescription Pattern ◽  
Mortality And Morbidity ◽  
Institutional Ethics ◽  
Tract Infections ◽  
Respiratory Conditions ◽  
Antimicrobial Prescription

Background: Infectious disease represent a major cause of mortality and morbidity in India. Pattern of use of antibiotics need to be studied separately as they vary from adult, however there is limited data is available, Therefore the aim of our study is to observe the drug utilization and antimicrobial prescription pattern and drug utilization in department of pediatrics at our tertiary care hospital.Methods: This was a prospective observational study carried out among indoor patients admitted to paediatric ward after obtaining approval by Institutional Ethics Committee. Written informed consent obtained from a parent or legal guardian of participants.Results: 100 patients were enrolled. The maximum number of antibiotics were prescribed from cephalosporin class (75; 43.6%) out of which ceftriaxone (42;56%), Cefixime (20;26.6%), cefotaxim (11;14.6%), cefpodoxime (3;4%), cefazolin (1;1.33%). The majority of cephalosporins were prescribed in Gastrointestinal tract infections (60.66%) followed by respiratory (27.2%) and least in cvs (2.66%), secondly higher group of antimicrobial prescribed was from Aminopenicillin class accounting of (36; 21.9%) which includes amoxiclav (35;97.2%), ampicillin (1;2.7%) and other beta lactamase (3;1.7%) consisting meropenem (2;66.7%), piperacillin with tazobatcam (1;33.3%). The majority of aminopenicillin were prescribed in respiratory tracts infections and very less in other systems. Miscellaneous drugs used in respiratory conditions were bronchodilator, systemic steroid and nasal decongestant; in CNS disorders antiepileptic and diuretics; in cardiovascular disease NSAID, inotropic, antihypertensive, diuretics; in genitourinary tract infections alkalizing agent and steroid and in GIT disorders minerals, rehydration fluids, antispasmodic probiotic were used.Conclusions: We conclude that commonly prescribed drugs were from 3rd generation cephalosporins followed from extended spectrum penicillin with β lactmase inhibitor. Majority of the antimicrobials are used empirically.

scholarly journals Study of antibiotic prescription pattern in PICU of a tertiary care hospital

2018 ◽  
Vol 7 (12) ◽  
pp. 2319
Author(s):  
Vivek Virbhan Bamel ◽  
Savita Ramesh Shahani
Keyword(s):  
Respiratory Tract ◽  
Antibiotic Prescription ◽  
Tertiary Care ◽  
Care Hospital ◽  
National Guidelines ◽  
Mortality And Morbidity ◽  
Institutional Ethics ◽  
Causes Of Mortality ◽  
Tract Infections ◽  
Written Informed Consent

Background: Infectious disease is one of the importance causes of mortality and morbidity in India, therefore pattern of use of antibiotics requires separate study as they differ from adult, Therefore the aim of our study is to observe the antibiotic prescription in the tertiary care hospital.Methods: A prospective observational study was carried out in the children admitted in PICU. The study was started after obtaining the approval from Institutional Ethics Committee. Written informed consent was obtained from a parent or legal guardian of participants.Results: There were 50 patients were enrolled. The maximum antibiotics were prescribed from cephalosporin class (42; 40.38%) which included ceftriaxone, cefixime, cefotaxim, cefpodoxime. The majority of cephalosporins were prescribed in miscellaneous cases followed by respiratory tract infections, gastrointestinal tract, Central nervous tract infections and nil in CVS cases, secondly higher number of antibiotics prescribed was metronidazole and from Aminopenicillin class which includes amoxiclav and ampicillin and another beta lactamase which includes ureidopenicilin and carbepenem. The majority of aminopenicillin were prescribed in miscellaneous group infections followed by respiratory tract infections.Conclusions: From this study, it can conclude that commonly antibiotic were from 3rd generation cephalosporins followed by metronidazole and other β lactamase inhibitor and all of the antibiotics were prescribed as per the national guidelines.

scholarly journals Evaluation of the Prescription Pattern of Antimicrobial Agents in Hospitalised Paediatric Patients in a Tertiary Care Hospital of Kathmandu, Nepal

2018 ◽  
Vol 38 (3) ◽  
pp. 157-162
Author(s):  
Anjan Khadka ◽  
Heleena Rayamajhi ◽  
Shova Shrestha
Keyword(s):  
Antimicrobial Agents ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Paediatric Population ◽  
Care Hospital ◽  
Prescription Rate ◽  
Upper Respiratory Tract ◽  
Prescription Pattern ◽  
Tract Infections ◽  
Antimicrobial Prescription

Introduction: Infectious diseases are one of the most frequent reasons for hospital admission for children and antimicrobials are commonly used to treat them. There is higher prevalence of irrational prescriptions of antimicrobials in such population. This study was conducted to survey the pattern of antimicrobial prescription in Paediatric inpatient. Material and Methods: This was retrospective, descriptive, observational study. The data was collected from prescription records. The paediatric population included in the study was categorised into three age groups. A total of 87 prescriptions were studied and the information was recorded in performa. Data were recorded in MS Excel and Graph Pad Prism version 6 was used for analysis. Results: The number of male child was outnumbered by female child. The average age of the patient on antimicrobial prescription was 5.34 ± 2.18 years. The mean duration of hospital stay was 6.17 ± 2.01 days. The common indications for antimicrobial prescriptions were upper respiratory tract infections, diarrhoeal illness, urinary tract infections, enteric fever, etc. The antimicrobials prescription rate was 1.33. Oral route was found to be commonly used than parenteral route. The generic prescription rate was 33.6%. The most common drug prescribed was ceftriaxone followed by amoxicillin + clavulanic acid, ciprofloxacin, metronidazole and amikacin. The 62.5% of antimicrobials were prescribed from National Essential List of Medicines. Conclusion: This study highlights the prescription pattern of antimicrobial agents in hospitalised Paediatric population in a tertiary care hospital.

scholarly journals A Prospective Observational Studies on Drug Utilization Evaluation and Rational Use of Corticosteroids in Tertiary Care Hospital

2020 ◽  
Vol 10 (5-s) ◽  
pp. 119-126
Author(s):  
Syeda Masarrath Unissa ◽  
Sana Kareem ◽  
Sumaiya Faheem Ahmed ◽  
Syed Imran Ul Haq ◽  
S Ahmedullah Hussaini Quadri
Keyword(s):  
Drug Interactions ◽  
Drug Utilization ◽  
Observational Studies ◽  
Demographic Data ◽  
Tertiary Care ◽  
Psychiatric Disease ◽  
Care Hospital ◽  
Prescription Pattern ◽  
Wide Range ◽  
Drug Utilization Evaluation

Background: Corticosteroids are widely prescribed Drugs in Hospitals, forming a part of standard treatment of modern medicine for a wide range of diseases, associated with inflammation and immune activation. Apart from beneficial effects they also produce number of adverse effects. In the present study, Prospective Observational studies on DUE (Drug utilization evaluation) and rationality of Corticosteroids has been Performed. Objectives: To Investigate the Drug utilization evaluation, Prescription pattern and Rationality of corticosteroids in various department of tertiary care teaching hospital. Methodology: A prospective observational study was conducted on 100 patients receiving corticosteroids in the various departments of Osmania general Hospital, Hyderabad. Patients prescribed corticosteroids therapy was included in the study. Exclusion of those patients with age less than 18, psychiatric disease, pregnant women and patients not willing to sign on consent form. Result: This study included 100 Patients out of which 68 were Male and 32 were female. In Age wise distribution, 15  Patients prescribed with corticosteroid in age group 18-28 years, 20  patients in 29- 38 years, 12 in 32-48 years, 16  in 49-58 years, 22 in 59-68 years, 11  in 69-78 years and 4  in above 80 years. This data showed that commonly male populations are more prone to diseases. As per the demographic data our finding shows that Budesonide was the most frequent prescribed corticosteroid (31.75%) followed by Hydrocortisone (26.19%), Dexamethasone (15.08%), Prednisolone 13.49%, Betamethasone (7.94%), Methyl prednisolone (5.56%). Out of 100 prescriptions total 10 ADRs and 25 Drug interactions were detected in this study. The majority of drug interactions were minor 24 followed by major 1. Conclusion: The Prescription pattern of corticosteroids was found to be rational as there is no Major drug interaction. Commonly geriatric population was more prone to diseases, for which steroids were used. Hence close observation is required to ensure safety, effectiveness and well-balanced therapeutic management with corticosteroids, both patients and prescribers should be more aware of the appropriate dose, dosage regimen, Drug - Drug interactions, ADRs and overall guidelines for corticosteroids prescribing. Keywords: Corticosteroids, Drug utilization evaluation, Prescription pattern.

scholarly journals A study of etiology and outcome of preterm birth at a tertiary care centre

2017 ◽  
Vol 6 (10) ◽  
pp. 4488
Author(s):  
Shaveta Garg ◽  
Tajinder Kaur ◽  
Ajayveer Singh Saran ◽  
Monu Yadav
Keyword(s):  
Preterm Birth ◽  
Tertiary Care ◽  
Preterm Births ◽  
Active Phase ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Mortality And Morbidity ◽  
High Incidence ◽  
History Of ◽  
Tract Infections

Background: Preterm births are still the leading cause of perinatal mortality and morbidity. It is a major challenge in the obstetrical health care.Methods: This study was conducted over a period of eight months from September 2016 till April 2017 at a tertiary care hospital. All patients who delivered a live baby before 37 weeks of gestation were included in the study.Results: Present study was conducted on 100 eligible women out of which 7 delivered before 30 weeks but majority of them (55%) delivered after 34 weeks of gestation. In our study, most of the patients (66%) presented in active phase of labor which resulted in preterm birth of baby. The most common risk factor of preterm labor was genitourinary tract infections (34%) followed by Preterm Premature rupture of membranes (22%). Past obstetric history of preterm delivery and abortions also had a significant impact on the present pregnancy outcome.Conclusions: Preterm labour and birth still have a high incidence causing significant neonatal mortality and morbidity as well as economic burden on family and hospital. The causes of preterm birth are multifactorial and modifiable. This incidence can be reduced by early identification of established risk factors, as revisited and reemphasized in our study, with the help of universal and proper antenatal care.

scholarly journals Prescribing pattern in outpatient department of neurosurgery in a tertiary care hospital of North India

2019 ◽  
Vol 7 (7) ◽  
pp. 2798
Author(s):  
Rehana Tabassum ◽  
Syed Sajad Hussain ◽  
Sajad Hussain Arif ◽  
Altaf Ramzan ◽  
Samina Farhat
Keyword(s):  
Lumbar Disc ◽  
Tertiary Care ◽  
Outpatient Department ◽  
North India ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Prescribing Pattern ◽  
Prescription Pattern ◽  
Mortality And Morbidity ◽  
Management Protocol

Background: The neurosurgical disorders are amongst the leading cause of global mortality and morbidity. Though surgical intervention is thought to be the main management protocol in the neurosurgical setup but drugs are being equally used especially in the outpatient setting. The present study was carried out in view of the sparse data available on prescribing pattern in neurosurgery.Methods: The present study was conducted by the department of pharmacology in outpatient department of neurosurgery in a tertiary care centre to look into the prescription pattern among these patients.Results: In 268 patients analyzed, mean age was 43.02±15.93 years and 52.23% were females. Majority of our participants (44%) were found to be of young to middle age group (21-40 years). The diagnosis among the study population was spread over large number of diseases. Lumbar Disc Prolapse (LDP) was found to be the leading cause of neurosurgical morbidity, amounting to 32%. As far as the prescription of various drugs in the outpatient of neurosurgery is concerned, Analgesics were the most common drugs prescribed constituting about 48% of the total drugs prescribed followed by GABA analogues and multivitamins which equally formed 41% of the total prescribed drugs.Conclusions: Although the prescription pattern studies among the outpatient neurosurgery patients are very scant, the analysis of prescription studies will be helpful to encourage the rational drug prescribing pattern.

scholarly journals A prospective study of prevalence of anti-microbial susceptibility of bacterial isolates in lower respiratory tract infections

2021 ◽  
Vol 10 (8) ◽  
pp. 915
Author(s):  
Ajaz Husaain ◽  
Qursheed Sultana ◽  
M. Abdur Rab Ansari
Keyword(s):  
Antibiotic Resistance ◽  
Respiratory Tract ◽  
Antibiotic Susceptibility ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Care Hospital ◽  
Lower Respiratory Tract Infections ◽  
Mortality And Morbidity ◽  
Tract Infections

Background: Lower respiratory tract infections (LRTIs) is one of the most common causes of mortality and morbidity across all age groups. In recent years, antibiotic resistance is constantly increasing. Thus, there is a need to monitor the bacteriological profile of pathogenic organisms. The present study aims to identify bacterial pathogens and their antibiotic susceptibility pattern.Methods: A prospective, observational, single centered study was conducted at tertiary care hospital for a period of 1 year i.e. from March 2016 to March 2017. A total of 733 sputum samples were collected and analyzed in microbiology lab. The samples went subjected to microscopy testing, culture and antibiotic sensitivity using suitable bacteriological methods.Results: From 733 sputum samples, about 51.34% were males and 48.56% were females. Approximately 49.65% of total samples were growth positive. Klebsiella was found to be the predominant microorganism followed by Methicillin sensitive Staphylococcus aureus (MSSA) and streptococcus. The gram-negative bacteria showed highest sensitivity for piperacillin/tazobactam, imipenem and ciprofloxacin. The gram-positive bacteria were found to be more susceptible for vancomycin, teicoplanin and amikacin.Conclusions: LRTIs are contagious form of disease and can rapidly disseminate among community. The irrational use of antibiotics complicates the management due to the antibiotic resistance. Local trend of antibiotic susceptibility pattern should be known as it helps in increasing the appropriate use of the antibiotics, decreasing the mortality and morbidity and reduces the anti-microbial resistance.

scholarly journals DRUG UTILIZATION PATTERN IN GERIATRIC PATIENTS ATTENDING OUT PATIENT DEPARTMENT AT RURAL TERTIARY CARE HOSPITAL IN MAHARASHTRA.

2017 ◽  
Vol 10 (2) ◽  
pp. 314
Author(s):  
Tushar B Nishandar ◽  
Anand S Kale ◽  
Harshal N Pise
Keyword(s):  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Drug Prescription ◽  
Demographic Data ◽  
Tertiary Care ◽  
Outpatient Department ◽  
Essential Medicines ◽  
Care Hospital ◽  
Drug Prescribing ◽  
Prescription Pattern

Objective: To observe a prescription pattern in elderly patients attending outpatient department (OPD) and evaluating prescriptions according to theWorld Health Organization (WHO) prescription indicators.Methods: A cross-sectional observational study was conducted from July to September 2015. Patients of either gender, age 60 years or more, attending OPD in tertiary care hospital were included in the study. Prescriptions of medical practitioners were collected and evaluated for demographic data and the WHO drug prescribing indicators.Results: A total of 600 patients were enrolled in the study. The majority of the patients were in the age group 60-69 years (66.33%) with male preponderance (61%). The average number of drugs per prescription was 3.41. Out of 2045 drugs prescribed, 1261 drugs (61.66%) were prescribed by their generic name and 784 drugs (38.33%) were prescribed by their brand name. 1700 drugs (83.12%) prescribed were from the WHOs essential medicines list 2015. Total encounters involving injectable usage were 0.15%. Drugs acting on the cardiovascular system (21.12%) were the most frequently prescribed, followed by nonsteroidal anti-inflammatory drugs (NSAIDs) (20%). Ranitidine (16.62%) is the most frequently prescribed drug. Conclusions: In this study, drug prescription pattern was rational as per the WHO drug prescribing indicators. However, issues such as polypharmacy and inaccuracies of dose and duration were seen.Keywords: Drug utilization study, Geriatric, Outpatient department, Rational use of medicines.

scholarly journals Drug utilization study of antibiotics in infectious diseases in a tertiary care hospital

2019 ◽  
Vol 8 (3) ◽  
pp. 469
Author(s):  
Kirti Rangdal ◽  
Anand Kanaki ◽  
Ketan Patil
Keyword(s):  
Tract Infection ◽  
Infectious Diseases ◽  
Drug Utilization ◽  
Wide Spectrum ◽  
Tertiary Care ◽  
Care Hospital ◽  
Mortality And Morbidity ◽  
Medical College ◽  
Drug Classes ◽  
Clinical Diagnoses

Background: Infectious diseases represent a major cause of mortality and morbidity in India. Irrational use of antibiotics can cause increase adverse drug reaction, leading to antibiotic resistance and increase in the treatment cost. Hence pattern of use of antibiotics need to be studied, therefore the aim of our study is to observe the antibiotics prescription pattern and drug utilization in department of medicine indoor patients at our tertiary care hospital.Methods: This was a prospective observational study carried out among indoor patients admitted in medicine ward and was conducted between January 2018 to March 2018 in Basaveshwara Teaching and General Hospital attached to M.R. Medical College, Kalaburagi. The data that was obtained was analysed and presented as percentages using descriptive statistics.Results: 100 patients were enrolled. The main reasons for admission were for diagnosis of respiratory tract infection (36%), GIT disorders (24%), Zoonotic disease (10%), Urinary tract infection (19%) and viral fever (11%). Most common antibiotic prescribed was ceftriaxone (40%), followed by piperacillin (26%). Average number of antibiotics per prescription was 1.7.Conclusions: For a wide spectrum of clinical diagnoses variety of drugs were utilized from various drug classes. Results showed that Cephalosporin was extensively used. As antibiotics are most commonly prescribed drugs and report of misuse is not uncommon so proper strategy like educational intervention and antibiotic policy are necessary to control this.

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