scholarly journals Prescription pattern of antiepileptic drugs in a tertiary care hospital

Author(s):  
Anu Mohan T. ◽  
Anuradha M.

Background: Epilepsy is a chronic neurological disorder which affects about 0.5% to 1% of the population. The older antiepileptic drugs like carbamazepine and phenytoin are the mainstay of treatment of epilepsy. With the development of newer drugs for various type of epilepsy, the prescribing pattern for epilepsy has changed over the last decade. The objective of this study was to evaluate the prescription pattern of antiepileptic drugs in outpatient department of a tertiary care health care centre in Kerala and to assess how adherent they are to the available treatment guidelines of epilepsy.Methods: Data was collected from patients attending the outpatient department of Neurology in Government Medical College, Kozhikode for 2 months from January 2018 to February 2018. A total of 442 patients were enrolled in the study and data regarding the type of epilepsy, the antiepileptic drug prescribed, and the demographic profile were recorded and analysed.Results: Among the study participants, 237 were males (53.6%) and 205 females (46.2%). The study showed that among the 442 participants enrolled, the most common type of epilepsy was focal seizures (64.5%) and the most commonly prescribed drug was carbamazepine (28%), followed by levetiracetam (22%) and valproate (20%). Majority of the patients were treated with a single drug (79.2%).Conclusions: Newer drugs have been increasingly added to the list of antiepileptic drugs, but most of them serve as adjuvant to older ones and the important drugs used as monotherapy are still the older ones.

2015 ◽  
Vol 18 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Farzana Sultana ◽  
Ajijur Rahman ◽  
Tripti Rani Paul ◽  
Md Shahid Sarwar ◽  
Md Anwar Ul Islam ◽  
...  

Irrational prescribing of drugs is a major health concern in developing countries like Bangladesh. A study was therefore undertaken in a hospital, situated in Rajshahi region of Bangladesh, to find the prescribing pattern and to detect the prescription errors to the admitted patients. Prescriptions of 200 patients were collected from various departments of the hospital over a period of three months. Prescription pattern was analyzed using general indicators suggested by WHO and prescribing errors were determined by comparing the prescribed drugs with national standard treatment guidelines, textbooks and authentic online resources. The average number of drugs per prescription was found to be 4.89 and 76.5% prescriptions contained complex regimen. In this study, we found no prescription with generic name. The percentage of prescription with antibiotics was 78% that was 15.95% of total drugs. The injectable preparations used were 17.18% of total 978 drugs. About 769 (3.85 per prescription) prescription errors were identified from 978 prescribed drugs. The name of 35 prescribed drugs was not clear due to illegible hand writing. The dose strength was missing for 279 drugs and 31 drugs had improper abbreviation. The study also identified 409 drug interactions. About 6.5% prescription orders were identified for the patients with kidney and urinary problems and there was no dose adjustment. Frequency of occurrence of prescription errors found during the study can be rated high. The prescription pattern and the prescription errors have indicated the need to establish proper system of recording and analyzing therapy before writing a prescription in order to promote rational drug therapy.Bangladesh Pharmaceutical Journal 18(1): 20-24, 2015


Author(s):  
Rehana Tabassum ◽  
Syed Sajad Hussain ◽  
Sajad Hussain Arif ◽  
Altaf Ramzan ◽  
Samina Farhat

Background: The neurosurgical disorders are amongst the leading cause of global mortality and morbidity. Though surgical intervention is thought to be the main management protocol in the neurosurgical setup but drugs are being equally used especially in the outpatient setting. The present study was carried out in view of the sparse data available on prescribing pattern in neurosurgery.Methods: The present study was conducted by the department of pharmacology in outpatient department of neurosurgery in a tertiary care centre to look into the prescription pattern among these patients.Results: In 268 patients analyzed, mean age was 43.02±15.93 years and 52.23% were females. Majority of our participants (44%) were found to be of young to middle age group (21-40 years). The diagnosis among the study population was spread over large number of diseases. Lumbar Disc Prolapse (LDP) was found to be the leading cause of neurosurgical morbidity, amounting to 32%. As far as the prescription of various drugs in the outpatient of neurosurgery is concerned, Analgesics were the most common drugs prescribed constituting about 48% of the total drugs prescribed followed by GABA analogues and multivitamins which equally formed 41% of the total prescribed drugs.Conclusions: Although the prescription pattern studies among the outpatient neurosurgery patients are very scant, the analysis of prescription studies will be helpful to encourage the rational drug prescribing pattern.


Author(s):  
DHIVYA K ◽  
SHIVA SHANKARI R ◽  
MOHAMMED ZULKARNANE A ◽  
GAUTAM R

Objective: The objective of conducting prescribing pattern study is to monitor, evaluate, and if necessary, recommend modifications in the prescribing behavior of medical practitioners. Hence, this study was conducted to analyze the drug utilization and prescribing pattern of drugs in orthopedic outpatient department (OPD). Methods: This prospective observational study was conducted in the orthopedic OPD of tertiary care hospital for a period of 3 months. Data were obtained from the prescriptions through one-to-one interviews and recorded in a separately designed case report form. Results: Out of the 260 patients enrolled in the study, 181 were female and 79 were male. The patients between the ages of 50 and 60 years constituted the higher number with a mean age of 52.2 years. The total number of drugs prescribed in the analyzed prescriptions was 1012 which includes orthopedic drugs as well as drugs prescribed to treat various comorbidities. The World Health organization drug prescribing indicators were used to assess the appropriate use of drugs. Conclusion: Our study concludes that drug utilization and prescribing quality should be improved by promoting medical education on current updates. The periodic audit should be conducted by a clinical pharmacist to reduce an error in the prescription as well as to check the compliance of prescription with standard treatment guidelines for rationalizing the therapy.


Author(s):  
Indu Slathi ◽  
Pradeep R. Jadhav ◽  
Pooja Deb ◽  
Shashwat Verma

Background: Cardiovascular diseases are the most frequent cause of morbidity and mortality throughout the world particularly in South Asian population. With advent of newer, highly efficacious heterogeneous drugs and changing treatment guidelines, there’s a need to identify the cardiologist preference and prescribing patterns for rational utilization.Methods: It was an open label, prospective, cross-sectional, descriptive type of study conducted in Cardiology Outpatients at a Tertiary care hospital, Navi Mumbai. The study included 100 patients suffering from cardiovascular diseases attending cardiology outpatient department from October 2016 to March 2017. Informed consent was obtained and the currently prescribed drug details were recorded from prescription. The data was analysed for WHO core prescribing indicators and different types of drugs prescribed.Results: The average number of drug products prescribed was 3.4. Most commonly prescribed drugs were Antiplatelets (23%) followed by Statins (19.71%), β blockers (16%), Nitrates (11.70%), Angiotensin converting enzyme inhibitors (8.03%), Calcium channel blockers (5.50%), Angiotensin receptor blockers (4.70%), Diuretics (2.55%), Anticoagulant (1.83%), α+β blocker (1.46%), Cardiac glycosides ((1.09%), Potassium sparing diuretic and central sympatholytics. Majority of drugs were prescribed as single drugs (79.88%) while 20.11% as fixed dose combination (FDC). The combination of Telmisartan + Hydrochlorthiazide was the commonest prescribed FDC. Majority drugs were prescribed from NEDL 2015, but documented low generic prescribing.Conclusions: Antiplatelet and Statins dominated the prescribing pattern with high prescribing trend from national essential drug list, but showed scope for improvement in encouraging the cardiologist to prescribe by generic name.


2021 ◽  
pp. 12-15
Author(s):  
Smarajit Banik ◽  
Sandip Saha ◽  
Sudipan Mitra ◽  
Ujjwal Pattanayak ◽  
Rajib Sikder ◽  
...  

Background: Diabetes mellitus is one of the important causes of morbidity and mortality. With a rise in non communicable diseases in India, diabetes has become a modern epidemic showing a rising trend in West Bengal also. A large number of diabetes patients come to the diabetes clinic of our tertiary care hospital in North Bengal Medical College and Hospital, Darjeeling, West Bengal. The large proportion of patients presenting with this condition prompted us to study the Sociodemographic and Anthropometric Prole of such patients. Methods: This was a descriptive hospital based cross sectional study involving a total of 344 diabetic patients enrolled in the diabetes clinic of a tertiary care teaching hospital from December 2019 to February 2020. A self-administered questionnaire was used to collect data and was analyzed in Microsoft excel sheet and using SPSS 20.0 software. Results: Among the 344 study participants, we found that 220 (63.95%) were males and 124 (36.05%) were females. Diabetes was more common among those aged 51-60 years 108 (31.40%). Family history was present among 188 (54.65%) of the diabetic patients. Almost 160 (46.51%) patients have diabetes 1.1 – 5 years. Hypertension was present among 216 (62.79%) patients. Almost 218 (63.37%) of the patients were overweight and 84 (24.42%) were obese. Conclusions: The diabetic patients presenting to this tertiary care hospital belong lower socioeconomic strata and having limited education in their age group. There is high proportion of obesity and hypertension among them.


2013 ◽  
Vol 3 (1) ◽  
pp. 29-31
Author(s):  
Swapna Bhattacharjee ◽  
Shekhar Bhattacharjee ◽  
Rukhsana Parvin

Background: Cough variant asthma (CVA) is a subset of asthma where the only symptom is chronic persistent cough. Many cases go unrecognized due to lack of proper evaluation. Response to asthma medication with features supportive of airway hypersensitivity helps in management of this disease. Objective: To find out the proportion of cough variant asthma among the patients attending medicine outpatient department of Enam Medical College, Savar, Dhaka. Materials and Methods: This cross sectional study was conducted in Enam Medical College Hospital, Savar, Dhaka over a period of two years from July 2009 to July 2011. Cough variant asthma was diagnosed mainly on clinical ground as chronic cough without wheezing, fever, weight loss, shortness of breath or sputum or any other apparent cause that persisted for more than eight weeks with absolutely normal physical examination of chest, normal chest radiography and blood count except raised eosinophil count and IgE level. Patients who met these criteria were given 2 weeks course of inhaler beclomethasone propionate and were assessed for improvement. Those who improved after steroid inhalation were categorised as having cough variant asthma. Results: Out of purposively selected 148 patients complaining only of chronic dry cough for more than eight weeks, 92 patients met the primary selection criteria for cough variant asthma. These 92 patients were given 2 weeks trial of 250 ìgm beclomethasone inhalation twice daily. Seventy nine patients reported almost complete recovery from chronic cough after 2 weeks and were categorized as having CVA. Thirteen patients did not improve and were not categorized as CVA. Conclusion: These findings suggest that cough variant asthma is the most common among the patients with chronic cough not due to any apparent cause. The efficacy of inhaled corticosteroid suggests that early intervention is effective in the treatment of this disease. DOI: http://dx.doi.org/10.3329/jemc.v3i1.13871 J Enam Med Col 2013; 3(1): 29-31


Author(s):  
Deepshikha Gupta ◽  
Narendra Joshi ◽  
Suman Mendiratta

Background: Methods: The present study is a single arm interventional study done at a tertiary care hospital in a metropolitan city. The study participants were the females who had infertility due to PCOS and resistant to clomiphene citrate, and participants were given HMG in a sequential manner with Clomiphene citrate and ovulation was observed using the TVS. Results: 79% of the study participants ovulated at the end of the study as a final outcome and only 25 participants who constitute 21% of the total had not ovulated. No cases of ovarian hyperstimulation and multiple gestation was reported. Conclusion: The study thus concludes that CC with low dose HMG is an efficient and safe method for induction of ovulation in females with  CC resistant PCOS related infertility without the dangers of OHSS and other adverse events, also the presence of normal BMI can help in a better rate of ovulation Keywords: HMG, TVS, Infertility


Author(s):  
Madhuri Kulkarni ◽  
Priyanka Ambekar ◽  
Siddharth Athawale

Background: Nutraceuticals use is increasing in a health-conscious society. Because of varying lifestyle diseases, people have changed their outlook towards nutraceuticals. The objective of the study was to study the prescription pattern of nutraceuticals by doctors in paediatric outpatient department of government medical college and hospital, Aurangabad, Maharashtra, India.Methods: This study was done between November 2018 to March 2019. Total of 156 patients were included in the study after obtaining written informed consent from parents of patients. The data was gathered, analysed and results were concluded.Results: Total 156 patients were prescribed nutraceuticals in paediatric outpatient department of which 51.92% female patients and 48.78% male patients received nutraceuticals. In this study, 62% patients received vitamins and 38% patients received vitamins and minerals. 67.31% patient receiving nutraceuticals were above the age of 6 years and 32.69% patients were under the age of 6 years. Among patients receiving nutraceuticals, B complex was received 55.77%. After that calcium lactate + vitamin D tablet were prescribed 21.80%. Ferrous sulfate + folic acid was received by 8.33% patients. Calcium carbonate + vitamin D3 were received by 7.69% patients. Folic acid tablet was received by 5.13% patients and poly-vitamin tablet by 1.28% patients. 100% prescriptions were prescribed in generic names.Conclusions: Nutraceuticals are being increasingly perceived as beneficial to health and are being continuously used in the treatment. The future of nutraceuticals is bright and can transform healthcare in a developing country like India.


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