scholarly journals Evaluation of knowledge, attitude and practices of postgraduate medical students towards clinical research in a tertiary care teaching hospital

2021 ◽  
Vol 10 (7) ◽  
pp. 800
Author(s):  
Sukhmeen Kaur Johar ◽  
Deepali L. Jaybhaye ◽  
Shruti Chandra ◽  
Prashant S. Mishra
Keyword(s):  
Clinical Trial ◽  
Medical Education ◽  
Graduate Students ◽  
Clinical Research ◽  
Tertiary Care ◽  
Willingness To Participate ◽  
Clinical Trial Registry ◽  
Cross Sectional ◽  
Post Graduate ◽  
Research Activities

Background: Clinical research is a component of medical and health research that facilitates valuable knowledge regarding diagnosis, prevention as well as treatment of a disease. Nowadays, the practise of medicine is evidence-based and combining medical education with clinical research provides a channel for translating scientifically advanced knowledge into better public health. The aim of the study was to assess knowledge (K), attitude (A), and practices (P) about clinical research among post graduate medical students.Methods: After obtaining institutional ethics committee approval, a cross-sectional and questionnaire-based study was conducted. A pre-structured and validated KAP questionnaire comprising of 25 questions (knowledge-15, attitude-5 and practices-5) was shared online through google forms with post graduate students. The responses to the questions were later marked correct or incorrect. The data was collected and compiled using Microsoft excel and expressed in percentage (%). Data analysis was performed using SPSS version 25.0.Results: 102 students responded to the questionnaire completely. Out of which males (55.9%) pre-dominated and majority of the PG students belonged to I year accounting for 40.2%. About 61.76% PG students were aware about a clinical research unit in the college. Majority of the students acknowledged the necessity of conducting clinical research and exhibited good knowledge about key concepts of clinical trials.  Even responses to questions pertaining to attitude towards clinical research were also majorly positive. On the contrary, more than 90% students had neither attended any workshop on ICH-GCP guidelines nor registered their academic study under clinical trial registry of India. However, 73.5% of them expressed their willingness to participate in a clinical trial in future.Conclusions: Although, assessment of knowledge and attitudes about clinical research among post graduate students showed positive results but discrepancies were observed in its practise. As such, this necessitates incorporation of clinical research activities into existing medical education system.

scholarly journals Assessment of knowledge, attitudes and practice among the post graduate students of dentistry and physiotherapy towards adverse drug reactions reporting and pharmacovigilance at a tertiary care centre at Indore, India

2018 ◽  
Vol 7 (4) ◽  
pp. 626
Author(s):  
Gopal Gudsurkar ◽  
Vikalp Tiwari ◽  
Pooja Solanki Mishra
Keyword(s):  
Graduate Students ◽  
Graduate Student ◽  
Single Point ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Post Graduate ◽  
Adr Reporting ◽  
Post Graduate Student

Background: Pharmacovigilance knowledge and training in post graduate student doctors is key factor for proper implementation of PvPI. Often the dentists and physiotherapists who are also one of the main stakeholders for ADR reporting are neglected for training and knowledge regarding pharmacovigilance. This study was planned to evaluate the knowledge and awareness of pharmacovigilance in post graduate students in tertiary care centre in Indore.Methods: It was a single point cross sectional questionnaire-based study conducted in a tertiary care Institute MGM Medical College and M.Y. Hospital in the state of Madhya Pradesh at Indore. It was conducted among post graduate student doctors from dentistry and physiotherapy. Total of 55 questionnaires were distributed, 50 of them were returned back and were analysed.Results: Overall knowledge level was average. 90% knew about ADR while 80% were aware about PVPI. 10% knew about local AMC at Indore while only 04% knew global centre for Pharmacovigilance is at Sweden Uppsala. 88% thought Med watch as global database for ADR against only 12% knew its Vigibase. 90% thought ADR reporting is necessary. 96% thought it should be included in UG curriculum. 98% had not reported any ADR till date while 84% had not seen an ADR form.Conclusions: Post graduate doctors are the prime candidates to impart the importance of pharmacovigilance. The study strongly suggested that there was a great need to create awareness and impart training among the post graduate doctors to improve the reporting of ADRs.

scholarly journals Assessment of clinical trials registered at clinical trial registry of India over past decade: an audit

2016 ◽  
Vol 3 (4) ◽  
pp. 238 ◽  
Author(s):  
Shruti S Bhide ◽  
Firoz Tadvi ◽  
Mitesh Maurya ◽  
Sunil Bhojne ◽  
Pragya Chandrakar
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Pharmaceutical Industry ◽  
Clinical Research ◽  
Clinical Studies ◽  
Descriptive Statistics ◽  
Trial Registry ◽  
Clinical Trial Registry ◽  
Post Graduate ◽  
The Past

<p class="abstract"><strong>Background:</strong> Clinical trial registry of India (CTRI) was launched in 2007. In this audit we attempted to assess the clinical research scenario over the past decade by looking at the information about clinical studies registered at the CTRI from 2007 to 2016.</p><p class="abstract"><strong>Methods:</strong> We accessed the official website of the CTRI i.e. www.ctri.nic.in and the required information was downloaded and descriptive statistics were used.</p><p class="abstract"><strong>Results:</strong> We found that the number of studies went on increasing from 31 in 2007 to 7060 in 2016 (as on 22<sup>nd</sup> June 2016). Majority studies were of interventional in nature as compared to observational and bioavailability and bioequivalence (BABE) studies. Pharmaceutical industry sponsored studies were comparatively higher in number than any other sponsored studies. However their number went on decreasing, while increase in registration of post graduate thesis and investigator sponsored studies was observed.</p><p><strong>Conclusions:</strong> Though a decrease in Pharmaceutical industry sponsored studies was observed the overall clinical research scenario appears to have improved due to investigator initiated studies and post graduate thesis.</p>

scholarly journals Willingness to Participate in Vaccine-Related Clinical Trials among Older Adults

2018 ◽  
Vol 15 (8) ◽  
pp. 1743 ◽  
Author(s):  
Divyanshu Raheja ◽  
Evelyn Davila ◽  
Eric Johnson ◽  
Rijalda Deović ◽  
Michele Paine ◽  
...  
Keyword(s):  
Older Adults ◽  
Clinical Trials ◽  
Clinical Research ◽  
Elderly Person ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Willingness To Participate ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Research Findings

The purpose of this study is to understand among a convenience sample of 400 adults aged 60 years of age or older (1) reasons for being willing or unwilling to participate in a vaccine clinical research study and (2) overall perceptions about vaccine clinical research. A cross-sectional study using a sample of older adults residing in the metro-Atlanta area and surrounding neighborhoods was conducted. The study questionnaire contained 37 questions, including questions about socio-demographics and perceptions about clinical trial processes. Statistical analysis was conducted using logistic regression. The adjusted modeling results indicated that sex, distance to research clinic, and being informed about the research findings played a role in the likelihood of an elderly person participating in a vaccine study. Males were more likely to participate in clinical trials as compared to females (OR: 2.486; CI: 1.042–5.934). Most participants were willing to travel up to 25 miles from the research clinic. Of the respondents, 45% were unlikely to participate if the results of the current trial are not shared. Improving access to clinical trials in terms of distance traveled and ensuring streamlined processes to inform participants about the results of the trial in the future would increase willingness to participate in vaccine clinical trials. The survey could serve as a useful tool for conducting vaccine studies and other clinical trials by understanding the barriers specific to the elderly.

scholarly journals Cross sectional study to assess the awareness of pharmacovigilance among post graduate residents of tertiary care medical college hospital of central India

2018 ◽  
Vol 7 (3) ◽  
pp. 386
Author(s):  
Pooja Solanki Mishra ◽  
Gopal Gudsurkar
Keyword(s):  
Graduate Student ◽  
Single Point ◽  
Tertiary Care ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Cross Sectional ◽  
Post Graduate ◽  
Global Database ◽  
Medical College ◽  
Post Graduate Student

Background: Pharmacovigilance knowledge and awareness in post graduate student doctors is key factor for proper implementation of PvPI. This study was planned to evaluate the knowledge &awareness of pharmacovigilance in post graduate students in tertiary care centre in Indore.Methods: It was a single point cross sectional questionnaire-based study conducted in a tertiary care Institute MGM Medical College & M.Y. Hospital in the state of Madhya Pradesh at Indore. It was conducted among post graduate student doctors from various clinical departments. Total of 150 questionnaires were distributed, 115 of them were returned back and were analysed.Results: Overall knowledge level was satisfactory. 91.30% knew about ADR while 95% were aware about PVPI. 13% knew about local AMC at Indore while only 4.34% knew global centre for Pharmacovigilance is at Sweden Uppsala. 86.95% thought Med watch as global database for ADR against only 13% knew its Vigibase. 96.50% thought ADR reporting is necessary. 97.40% thought it should be included in UG curriculum. 95.65% had not reported any ADR till date while 86.95% had not seen an ADR form.Conclusions: Post graduate doctors are the prime candidates to impart the importance of pharmacovigilance. The study strongly suggested that there was a great need to create awareness among the post graduate doctors to improve the reporting of ADRs.

Participation of elderly gynecological cancer patients in clinical trials.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e21520-e21520
Author(s):  
Katharina Prieske ◽  
Fabian Trillsch ◽  
Gulten Oskay-Oezcelik ◽  
Radoslav Chekerov ◽  
Eva-Maria Schoening ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Gynecological Cancer ◽  
Educational Background ◽  
General Information ◽  
Willingness To Participate ◽  
Study Participation ◽  
Long Distance ◽  
Cross Sectional ◽  
Potential Study

e21520 Background: Elderly patients (pts) are underrepresented in clinical trials in gynecological cancer, even though they are disproportionally often affected. This study aimed to evaluate disposition and apprehension of elderly pts towards study participation. Methods: 112 elderly gynecological cancer pts (median age 70; range 65-92) were surveyed in a multicenter cross-sectional study. Besides fitness, state of disease, education and domestic situation, questions aimed at the general willingness to participate in a clinical trial. Personal reasons for rejection and suspected advantages/disadvantages that might evolve from participation were inquired. Results: Willingness to participate in a study was generally high (66.1%, 74/112). 42/112 (37.5%) had given their consent to participation in a study before, 12.5% (6/48) refused even though they were offered participation. Reasons for potential study participation were: ‘better monitoring of the disease’ (51/112), ‘better medical care’ (35/112), ‘to help medical research’ (31/112), ‘better medication’ (27/112) and ‘because of my doctor’s recommendation’ (17/112). Reasons for potential refusal were: ‘too time consuming’ (19/112), ‘fear of side effects’ (17/112), ‘misuse as experimental animal’ (14/112), ‘long distance to clinic’ (11/112) and ‘too little or unclear information’ (7/112). 26.1% (29/112) of pts stated, that they had ‘no objection’ against study participation. The question if pts anticipated having a longer life due to study participation was answered with ‘yes’ or ‘rather yes’ in 33.9% (38/112), 23.2% answered ‘no’ or ‘rather no’ (23.2% undecided). No relation between willingness to participate in a study and general fitness (p = 0.311), education (p = 0.631) or domestic situation (p = 0.195) could be observed. However, with increasing age, willingness decreased (p = 0.029). Conclusions: Elderly pts are generally willing to participate in clinical studies regardless of their fitness or educational background. Benefits of participation seem to be unclear among a majority of potential study participants. Therefore it might be decisive to provide more general information regarding benefits and safety for the elderly pts in a clinical trial.

scholarly journals Pandemic and medical education of surgical residents in a tertiary care hospital in India: a cross-sectional study

2021 ◽  
Vol 8 (10) ◽  
pp. 2974
Author(s):  
Raghul Sekar ◽  
Arun Alexander ◽  
Kalaiarasi Raja ◽  
Sunil Kumar Saxena
Keyword(s):  
Medical Education ◽  
Residency Training ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Working Hours ◽  
Maslach Burnout Inventory ◽  
Care Hospital ◽  
Cross Sectional ◽  
Surgical Residents ◽  
Hands On

Background: COVID-19 pandemic has brought tremendous changes in the functioning of residency training. The impact was maximal on surgical residents whose hands-on training was affected. This study aimed to assess the effect of COVID-19 pandemic on medical education and training of surgical residents. Methods: A single institutional cross-sectional survey was conducted in a large tertiary care hospital in India. It included residents in various surgical specialties. The survey was divided into six sections to cover all the aspects of their residency.Results: Out of 106 residents who participated in the study, 95 (59.3%) had worked in the dedicated COVID-19 facility, and 97 (91.5%) feared transmitting the infection to their family members. There was a considerable reduction in both elective and emergency surgeries performed by residents (p<0.05).There was a significant reduction in the working hours per day, helping residents get more time for research work. Further Maslach burnout inventory score was 7.43±2.35 after the pandemic, which shows a statistically significant reduction (p<0.001) in residents' burnout.Conclusions: Surgical residents had to balance their residency training with caring for COVID-19 patients. There had been a decrease in their hands-on training, clinical exposure, and working hours. Both theoretical and practical training of surgical residents has been affected during this pandemic. This survey can be used as a tool to improve the lives of surgical residents in any pandemic situation or during further waves of COVID-19.

scholarly journals Frequency of Depression, Anxiety and Stress among Gynae Residents during Covid Pandemic

2021 ◽  
Vol 15 (7) ◽  
pp. 1894-1897
Author(s):  
Imran Khan ◽  
Muhammad Zaman Afridi ◽  
Zahra Wasim ◽  
Nadia Khan Jawad ◽  
Zubaida Khanum Wazir ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Psychological Impact ◽  
Moderate Level ◽  
Teaching Hospitals ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Post Graduate ◽  
Ethical Approval ◽  
Community Data ◽  
Tertiary Care Hospitals

Objective: To find the frequency of depression, anxiety and stress among Gynae residents during covid pandemic. Methodology: This Cross-sectional survey was carried out in different Teaching Hospitals of Khyber Pakhtunkhwa during the period of six months i.e from August 2020 to January 2021. After the ethical approval from the research community, data was collected from Post Graduate Gynae Residents of Teaching Hospitals. Sample size for the study was 405 participants. Depression, anxiety and gross scale shorten version DASS-21 containing 21 items was standard research to use in study i.e. depression, anxiety and stress was identified on the basis of their cutoff scores i.e. normal scores were ≥10, ≥8 and ≥15 for depression, anxiety and stress respectively. Result: In depression, 136 (34%) participants were normal followed by moderate level having frequency 121 (30.25%). In the anxiety category, 116 (29%) participants were normal followed by moderate level having frequency 101 (25.5). In the category of stress, 179 (44.75%) participants were normal followed by mild levels having frequency 106 (26.50%). Only COVID positive status was statistically significant with depression, anxiety and stress as their P-valve was 0.02 less than 0.05. Conclusion: Considerable number of post graduate Gynae trainees working in different tertiary care hospitals have varying degrees of depression, anxiety and stress due to COVID-19 pandemic. Keywords: COVID-19, Pandemic, Post graduate, Psychological impact, Trainee doctors, Gynae residents, Mental health, Obstetrics, Gynaecology.

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