scholarly journals Premature ovarian failure incidence, risk factors and its relation to BMI and infertility

2019 ◽  
Vol 8 (3) ◽  
pp. 947
Author(s):  
Smita Baheti ◽  
Anjana Verma ◽  
Medhavi Sharma
Keyword(s):  
Risk Factors ◽  
Menstrual Cycle ◽  
Premature Ovarian Failure ◽  
Ovarian Failure ◽  
Outpatient Department ◽  
Medical College ◽  
Incidence Risk ◽  
Menstruating Women ◽  
Menstrual Disturbances

Background: Premature ovarian failure (POF) is cessation in the normal functioning of the ovaries in women younger than age 40 years. It is estimated to affect1% of women younger than 40 years and 0.1% of those under 30 years. Premature ovarian failure is a common cause of infertility in women.Methods: Patient attending outpatient Department of Obstetrics and Gynecology with age less than 40 years and complaint of menstrual disturbances, symptoms of menopause were enrolled for the study for duration of 1year. This study is planned to calculate the incidence, risk factors, relation to BMI and infertility in patients attending outpatient department at Geetanjali medical college and hospital, Udaipur for all enrolled patient coming with complaints of menstrual disturbances. FSH levels were send for all the patients and those with FSH level more than 20 at day 2/3 for menstruating women and random FSH level for amenorrhea patient more than 20 were classified in to study group and all those women with FSH less than 20 are taken as control group.Results: Present study strongly suggests that simple laboratory test FSH and symptoms of missed and irregularity of menstrual cycle help in early and prompt diagnosis of premature ovarian failure. And early diagnosis helps in avoiding unnecessary medications and helps in improving long term morbidity.Conclusions: Disturbances in menstrual cycle like amenorrhea and infrequent cycles are the symptoms which are associated with premature ovarian failure after ruling out pregnancy and other hormonal and structural causes.

Postoperative flat anterior chamber: incidence, risk factors, and effect on the long-term success of trabeculectomy

2013 ◽  
Vol 57 (6) ◽  
pp. 520-528 ◽  
Author(s):  
Takeshi Ono ◽  
Kenya Yuki ◽  
Daisuke Shiba ◽  
Takayuki Abe ◽  
Keisuke Kouyama ◽  
...  
Keyword(s):  
Risk Factors ◽  
Anterior Chamber ◽  
Incidence Risk ◽  
Flat Anterior Chamber

Acute kidney injury following coronary angiography: a nationwide study of incidence, risk factors and long-term outcomes

2018 ◽  
Vol 31 (5) ◽  
pp. 721-730 ◽  
Author(s):  
Dadi Helgason ◽  
Thorir E. Long ◽  
Solveig Helgadottir ◽  
Runolfur Palsson ◽  
Gisli H. Sigurdsson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Coronary Angiography ◽  
Kidney Injury ◽  
Long Term Outcomes ◽  
Nationwide Study ◽  
Incidence Risk

scholarly journals Incidence, risk factors, and longitudinal outcome of seizures in long-term survivors of pediatric brain tumors

Epilepsia ◽  
2015 ◽  
Vol 56 (10) ◽  
pp. 1599-1604 ◽  
Author(s):  
Nicole J. Ullrich ◽  
Scott L. Pomeroy ◽  
Kush Kapur ◽  
Peter E. Manley ◽  
Liliana C. Goumnerova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Brain Tumors ◽  
Pediatric Brain Tumors ◽  
Longitudinal Outcome ◽  
Incidence Risk ◽  
Long Term Survivors ◽  
Pediatric Brain

Tachycardiomyopathy Complicated by Focal Atrial Tachycardia: Incidence, Risk Factors, and Long-Term Outcome

2014 ◽  
Vol 25 (9) ◽  
pp. 953-957 ◽  
Author(s):  
WEIZHU JU ◽  
BING YANG ◽  
MINGFANG LI ◽  
FENGXIANG ZHANG ◽  
HONGWU CHEN ◽  
...  
Keyword(s):  
Risk Factors ◽  
Atrial Tachycardia ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Incidence Risk ◽  
Focal Atrial Tachycardia

Study of incidence of premature ovarian failure in patient attending outpatient department for infertility in a tertiary care centre

2019 ◽  
Vol 8 (10) ◽  
pp. 3926
Author(s):  
Qazi Jaweria Amber ◽  
Tushar Tatyaba Palve
Keyword(s):  
Premature Ovarian Failure ◽  
Wide Spectrum ◽  
Tertiary Care ◽  
Ovarian Failure ◽  
Outpatient Department ◽  
Obstetrics And Gynecology ◽  
Premature Menopause ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Presenting Symptoms

Background: To assess the incidence of premature ovarian failure in cases attending infertility outpatient Department of Obstetrics and Gynecology in a tertiary care centre. A total of 350 patients attending infertility opd were screened over period of 150 days from which authors observed premature menopause in 10 cases accounting for an incidence of 2.8%. POF affects approximately one in 10,000 women by age 20; one in 1,000 women by age 30; one in 100 women by age 40.  Premature ovarian failure is a common cause of infertility in women.Methods: Patient attending outpatient Department of Obstetrics and Gynecology with age less than 40 years and infertility, symptoms of menopause were enrolled for the study for duration of 150 days.Results: Present study authors found a total of 2.8% of patient presenting in our outpatient department for infertility had Premature ovarian failure.80% of them were symptomatic suffering with symptoms of hormonal deficiencies .100% of patient with infertility diagnosed as premature ovarian failure had low AMH and High FSH and LH levels indicating poor prognosis.Conclusions: Patient presenting with infertility and amenorrhoea can be cases of premature menopause. Here it is essential to investigate and treat the patient. Infertility might be one of the early presenting symptoms if not the first one. These patients if treated and diagnosed early can have a better living. Considering the wide spectrum of functional derangements in patient with early menopause and benefits of early hormone replacements these patients should be diagnosed and treated early.

scholarly journals PREMATURE OVARIAN FAILURE, ITS CONSEQUENCES, MORTALITY AND IMPACT ON THE CARDIOVASCULAR SYSTEM

2021 ◽  
Vol 9 (1) ◽  
pp. 147-156
Author(s):  
S.V. Lopukhov ◽  
◽  
E.V. Filippov ◽  
Keyword(s):  
Cardiovascular Diseases ◽  
Premature Ovarian Failure ◽  
Correct Diagnosis ◽  
Vascular Diseases ◽  
Ovarian Failure ◽  
Pharmacological Therapy ◽  
The Body ◽  
Risk Of Death ◽  
Increased Risk

This review focuses on the topic of premature ovarian failure (POF) as highly relevant in modern medicine (up to 2% of women in the population suffer from this disease). However, patients with premature ovarian failure not only are still not receiving any treatment, but even making this diagnosis is very difficult. Even after a correct diagnosis is made, these patients are not followed up, despite the fact they have already developed a hormonal imbalance. These women develop two groups of complications: short-term complications associated with a rapid estrogen deficiency in the body, and much more dangerous long-term complications affecting multiple organs and even systems. But in the meanwhile, women with premature ovarian failure are under increased risk of death from all causes, in particular from coronary heart disease (CHD), respiratory diseases, genitourinary diseases and from external causes. And this is despite the fact that cardio-vascular diseases (CVD) are already the leading cause of death among women worldwide. It is women with POF that are at the highest risk of development of cardiovascular diseases, compared to women with normal menopause. These patients, therefore, constitute one of the most important groups to be targeted by screening and prevention strategies primarily for cardiovascular diseases. These strategies should include the use of risk stratification tools to identify women that need lifestyle modifying and pharmacological therapy to prevent development of such diseases in them. This is the only way to maintain a high quality of life in these women over the long term.

scholarly journals Role of centchroman versus danazol in treatment of benign breast disorders

2021 ◽  
Vol 8 (2) ◽  
pp. 616
Author(s):  
Hanuman Ram Khoja ◽  
Bodu Ram Barala ◽  
Saurabh Sharma ◽  
Prabha Om ◽  
Devendra Saini
Keyword(s):  
Side Effects ◽  
Menstrual Cycle ◽  
Dynamic Structure ◽  
Physiological Changes ◽  
Lump Size ◽  
Medical College ◽  
Menstrual Irregularities ◽  
Lh Rh

Background: The breast is a dynamic structure that undergoes cyclical changes throughout the menstrual cycle. Any aberration from normal physiological changes in breast produces different problem in breast. Many drugs are used for treatment for these disorders like Danazol, Bromocriptine, Tamoxifen and LH-RH analogue but still no consensus for any drug is present.Methods: The aim of our study was to analyze the effectiveness of drug Centchroman and its comparison with Danazol in treatment of benign breast disorders in respect to symptoms relief, decrease in nodularity and lump size, recurrence, cost and side effects of drug. This prospective study was conducted on 250 patients of benign breast disorders attending surgical OPD between May 2018 to September 2019 in SMS medical college and Hospital, Jaipur.Results: Tolerance and improvements in symptoms in centchroman group was more than danazol (100% vs 92.8%) with less recurrence in former group. While side effects varied between the two groups with menstrual irregularities more common in centchroman group.Conclusions: The study shows that centchroman is safe, more effective and less expensive to Danazol for the treatment of benign breast disorders in long term.

scholarly journals Incidence, Risk Factors and Impact on Long-Term Outcome of Postoperative Delirium After Transcatheter Aortic Valve Replacement

2021 ◽  
Vol 8 ◽  
Author(s):  
Victor Mauri ◽  
Kevin Reuter ◽  
Maria I. Körber ◽  
Hendrik Wienemann ◽  
Samuel Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Transcatheter Aortic Valve Replacement ◽  
Postoperative Delirium ◽  
Vascular Complications ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Transcatheter Aortic Valve ◽  
Incidence Risk ◽  
Male Sex

Background: The aim of the present study was to analyze incidence, risk factors, and association with long-term outcome of postoperative delirium (POD) after transcatheter aortic valve replacement (TAVR).Methods: Six hundred and sixty one consecutive patients undergoing TAVR were prospectively enrolled from January 2016 to December 2017. POD was assessed regularly during ICU-stay using the CAM-ICU test.Results: The incidence of POD was 10.0% (n = 66). Patients developing POD were predominantly male (65%), had higher EuroSCORE II (5.4% vs. 3.9%; P = 0.041) and were more often considered frail (70% vs. 26%; P < 0.001). POD was associated with more peri-procedural complications including vascular complications (19.7 vs. 9.4; P = 0.017), bleeding (12.1 vs. 5.4%; P = 0.0495); stroke (4.5 vs. 0.7%; P = 0.025), respiratory failure requiring ventilation (16.7% vs. 1.8%; P < 0.001), and pneumonia (34.8% vs. 7.1%; P < 0.001). Consequently, patients with POD had significantly longer ICU- (7.9 vs. 3.2 days P < 0.001) and hospital-stay (14.9 vs. 9.0 days; P < 0.001), and higher in-hospital mortality (6.1 vs. 2.1%; P = 0.017). Logistic regression analysis identified male sex (odds ratio (OR) 2.2 [95% confidence interval (CI) 1.2–4.0); P = 0.012], atrial fibrillation [OR 3.0 (CI 1.6–5.6); P < 0.001], frailty [OR 4.3 (CI 2.4–7.9); P < 0.001], pneumonia [OR 4.4 (CI 2.3–8.7); P < 0.001], stroke [OR 7.0 (CI 1.2–41.6); P = 0.031], vascular complication [OR 2.9 (CI 1.3–6.3); P = 0.007], and general anesthesia [OR 2.0 (CI 1.0–3.7); P = 0.039] as independent predictors of POD. On Cox proportional hazard analysis POD emerged as a significant predictor of 2-year mortality [HR 1.89 (CI 1.06–3.36); P = 0.030].Conclusion: POD is a frequent finding after TAVR and is significantly associated with reduced 2-year survival. Predictors of delirium include not only peri-procedural parameters like stroke, pneumonia, vascular complications and general anesthesia but also baseline characteristics as male sex, atrial fibrillation and frailty.

scholarly journals Assessment of risk factors and prediction of premature ovarian failure

2021 ◽  
Author(s):  
L. V. Tkachenko ◽  
I. A. Gritsenko ◽  
K. Yu. Tikhaeva ◽  
N. I. Sviridova ◽  
I. S. Gavrilova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Flow ◽  
Early Diagnosis ◽  
Premature Ovarian Failure ◽  
Follicle Stimulating Hormone ◽  
Diagnostic Value ◽  
Ovarian Failure ◽  
Ovarian Volume ◽  
Pathological Conditions ◽  
Instrumental Methods

The problem of premature ovarian failure (POF) is currently in the spotlight of obstetricians and gynecologists worldwide. Early diagnosis of this pathology is necessary to prevent the development of serious pathological conditions. The systematization of modern ideas about laboratory and instrumental methods for POF diagnosing, assessing diagnostic value of parameters such as follicle stimulating hormone, anti-Mullerian hormone as well as the count of antral ovarian follicles, intraovarian blood flow and ovarian volume using ultrasound techniques, which can then be used as prognostic criteria for POF comprise a very important modality. Based on the findings obtained, early detection may lead to proposing new prognostic strategies.

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