scholarly journals Moderate to severe maternal anaemia in pregnancy and its impact on perinatal outcome in tertiary care hospital

Author(s):  
Ashram Khatana ◽  
Suniti Verma ◽  
Ram Narain Sehra ◽  
Kanti Yadav

Background: Anaemia is the commonest medical disorder in pregnancy and has a varied prevalence, etiology and degree of severity in different populations. The purpose of this study was to evaluate the prevalence of maternal anaemia in pregnancy and its impact on perinatal outcome.Methods: This was a prospective observational study conducted in department of obstetrics and gynecology JLN Hospital Ajmer, Rajasthan, India from October 2015 to December 2016. Total 325 pregnant women were included in the study who fulfilled the inclusion criteria and found to have moderate to severe anaemia.Results: Prevalence of anaemia in pregnancy was 80% in present study. Perinatal mortality was 13.3% in moderate anaemia and in severe anaemia 42%. In present study maximum 56% of cases were in the age group of 20-25 years, and maximum number of cases were primigravida (33.84%). Out of 225 cases of moderate anaemia only 50 cases (22.22%) had antenatal check-up once or twice. Out of 225 cases of moderate anaemia, 66.66% cases were rural and 33.33% cases were of urban group. Fetal outcome in present study was in form of 49.23% premature birth with 33.12% perinatal mortality.Conclusions: Maternal anaemia in pregnancy is associated with illiteracy, low socioeconomic status, multiparity, inadequate antenatal care and rural geographic area.  Severe anaemia was associated with high perinatal mortality.

Author(s):  
Sonali J Ingole ◽  
Shilpa N Chaudhary

Introduction: Over the years, continuous efforts have been made for improving reproductive health status of women. In India, Ministry of Health and Family Welfare (MoHFW) has set Maternal Near Miss (MNM) review operational guidelines. Aim: Analysis of the incidence and causes of MNM cases in tertiary care hospital. Materials and Methods: This retrospective observational study was undertaken at a tertiary care hospital from January 2010 to September 2018. MNM cases were identified according to the criteria given by MoHFW, MNM review operational guidelines. Following parameters (variables) were noted viz., age, parity, obstetric haemorrhage, severe anaemia, sepsis, therapeutic interventions, etc., and analysed. Quantitative data was analysed by calculating means, ratios and proportions, using SPSS software (Version 21.0). Results: There were total 36,366 deliveries during the study period. A total of 315 Maternal Near Miss cases were noted. Hypertensive disorders n=133 (42.2%) in pregnancy was the leading cause of MNM events at the hospital. This was followed by obstetric haemorrhage n =97 (30.79 %), and severe anaemia constituting n=36 (11.42%), and Sepsis n=30 (9.52%). Mortality index was highest in the sepsis group n=5 (14.28%) followed by severe anaemia n=3 (7.69%). Conclusion: Hypertensive disorders were most common cause of near miss cases followed by obstetric haemorrhage. Sepsis was commonest cause of maternal mortality. Early identification of hypertensive disorders in pregnancy, obstetric haemorrhage, severe anaemia and sepsis; and prompt treatment of these causes may help in reducing near miss and maternal mortality.


2016 ◽  
Vol 15 (1) ◽  
pp. 90-94
Author(s):  
Srabani Chakrabarti ◽  
Kajari Mandal ◽  
Swapan Pathak ◽  
Arabinda Patra ◽  
Subrata Pal

Introduction: Anaemia in pregnancy is still a major concern in reducing maternal morbidity and mortality in India particularly in rural population. Haemoglobinopathies are important contributors to anaemia in pregnancy in rural India particularly in tribal population. Beta thalassemia is the commonest type of haemoglobinopathy all over the world. Thalassemia and other haemoglobinopathies are highly prevalent among the tribal communities in West Bengal. Bankura is one of the districts of West Bengal where more tribal population are present. So detection and prevention of thalassemias is one of the major public health problems in this part of the state of West Bengal. Study done by Manna et al4 showed that about 10% of the population is carrier of haemoglobin disorder. This study was taken up to document the recent prevalence status of hemoglobinopathies particularly Thalassemias and coexistence of iron deficiency anaemiasObjective: To find out prevalence of haemoglobinopathies and to compare the prevalence of different types of Thalassemias among the antenatal mothers.Materials and Methods: This study was carried out in Bankura Sammilani Medical College (BSMC), Bankura West Bengal among 3500 tribal and non-tribal antenatal mothers. Cation exchange-high performance liquid chromatography (CE-HPLC) is being used for investigation for hemoglobinopathies and thalassemias. Together with a complete blood count, the CE-HPLC is effective in categorizing hemoglobinopathies as traits, homozygous disorders and compound heterozygous disorders.Results: In our study 275 mothers had haemoglobinopathy. The commonest disorder we encountered was Beta Thalassemia trait (57.5%), followed by HbE carrier (36%), homozygous HbE disease (1%), HbS carrier (4%), HbE Beta Thalassemia (1.5%).Bangladesh Journal of Medical Science Vol.15(1) 2016 p.90-94


2012 ◽  
Vol 1 (2) ◽  
pp. 17-20
Author(s):  
Mahamuda Begum ◽  
Shamim Ara ◽  
Shahnaz Begum ◽  
Segupta Kishwara ◽  
Khondaker Abu Rayhan ◽  
...  

Background: Birthing process is the journey of the spirit/ soul. The Placenta is the home for this spirit/ soul for nine months. Placenta has a huge role to play throughout the pregnancy acting as the kidneys, lungs and intestines all in one1. Placenta is an organ that is essential to the survival and growth of the fetus of the mammals. Anaemia in pregnancy is common and one of the risk factors in pregnancy. Maternal anaemia result in fetal hypoxemia and also stimulates placental growth. In anaemia, significant changes both in gross morphology and in histology of the placenta can occur. Type of study: Descriptive. Place of study: Department of Anatomy, Dhaka Medical College, Dhaka. Study period: July 2005 to June 2006. Methods: Sixty (60) placentas of Bangladeshi pregnant women were studied. Out of 60 placentas, anaemic and control group were 40 and 20 respectively. The study was designed to determine, morphological changes of placenta which is influenced by maternal anaemia. Macroscopic dimension of the placenta were measured with observation and dissection method. The samples were divided into group A (control), group B1 (mild anaemia), group B2 (moderate anaemia) and group B3 (severe anaemia). The severe group was not found in present study. Result: In anaemia, placental diameters, surface area and thickness were increased. Conclusion: There were morphological changes of the placenta in association with maternal anaemia. However, comprehensive work considering the physiological, biochemical, genetic as well as further gross, light, electron microscopic and morphometric placental studies are needed in order to support the findings of present study. DOI: http://dx.doi.org/10.3329/jssmc.v1i2.12161 Journal of Shaheed Suhrawardy Medical College Vol.1, No.2, December 2009 p.17-20


Author(s):  
Rashmi Kumari ◽  
Usha Kumari ◽  
Krishna Sinha

Aim: To assess the maternal anaemia, intra-uterian growth restriction and neonatal outcome. Materials and methods: a prospective, observational study conducted in Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College and Hospital, Bhagalpur, Bihar India. A total of 240 consecutive clinically suspected cases of IUGR with singleton pregnancies at 34-40 weeks of gestation were included in the study.  Their socio-demographic profile and hemoglobin levels were recorded. A descriptive analysis of the data was performed. Results: Of 240 study subjects with IUGR at 34-40 weeks, 70.4% were anaemic, (48.8% had mild, 20.8% had moderate, 0.83 % had severe anaemia) while 29.6% were not anaemic. Significantly, the ratio of anaemic to non anaemic in antenatal IUGR pregnancies was 2.48:1. A birth weight of less than 2.5 kgs was recorded in 84% of pregnancies with moderate anaemia and 83.8% pregnancies with mild anaemia. Out of the 240 clinically diagnosed cases of IUGR 71.25% (n=171) were from the rural background and 28.75% (n=69) were urban area. Conclusion:  Mild to severe anaemia in IUGR may increase the chances of low birth weight and adverse neonatal outcomes but larger studies with standardized definitions and measurements of exposure outcomes to bring about uniformity are required to determine an accurate assessment of association between low maternal hemoglobin and IUGR


2015 ◽  
Vol 7 (1) ◽  
pp. 22-25
Author(s):  
Afshaan Ambreen ◽  
Farhatulain Ahmed ◽  
Attia Sheikh ◽  
Muhammad Rashid Ayub ◽  
Numeera Faryad ◽  
...  

ABSTRACT Objective The objective of the study is to find the effect of jaundice during pregnancy on fetomaternal outcome over a 10-year period at tertiary care hospital. Materials and methods An analysis of fetomaternal outcome of all case records with jaundice in pregnancy from January 2003 to December 2013 is made. Results The incidence of jaundice in our study is one in 278 pregnancies, with the disease more common in younger age group. Viral hepatitis found to be the commonest cause, HEV being the commonest with a high maternal and perinatal mortality. Obstetric cholestasis being the second most common followed by HELLP syndrome, AFLP and sepsis; Hepatorenal failure, encephalopathy, DIC and PPH were the main causes of maternal mortality. Conclusion Viral hepatitis is most prevalent cause of jaundice in pregnancy, associated with a high maternal and perinatal mortality and morbidity. How to cite this article Ambreen A, Ahmed F, Sheikh A, Ayub MR, Faryad N, Mushtaq S. Jaundice in Pregnancy: A Clinical Study at Fatima Memorial System. J South Asian Feder Obst Gynae 2015;7(1):22-25.


Author(s):  
Prasanna Kumar Shetty ◽  
Akhila G. Menon ◽  
Rekha Rai

Background: Bacterial Vaginosis (BV) is the most common lower genital tract syndrome in women of age group 16 to 25years.BV is a disorder of the vaginal microbial ecosystem characterized by a shift in the vaginal flora, from the normally predominant Lactobacillus species to one dominated by a mixed flora. The prevalence of BV can be around 15-30% and upto 50% in pregnancy. This study aims to study the prevalence of BV and their adverse outcomes on pregnancy.Methods: It is a Cross Sectional Study at Department of Obstetrics and Gynecology, at a tertiary care hospital, for a period of one and half year from November 2016-April 2018.Pregnant women attending antenatal clinic were enrolled after obtaining an informed consent and vaginal swab examination done. The sample size was 200.Results: The prevalence of BV in pregnant females was 18%. The major risk factors for BV in pregnancy were young age, low socioeconomic status and recent sexual activity. All patients who took treatment for BV had good outcome. Amsel criteria had low sensitivity but very high specificity(95%).Individually vaginal PH had a very high sensitivity(91.6%) when compared to the gold standard Gram stain.Conclusions: Routine screening is recommended for all pregnant women with risk factors and with symptoms. Early diagnosis and treatment in pregnant women who are asymptomatic and with no risk factors can prevent adverse outcome.


2018 ◽  
Vol 37 (3) ◽  
pp. 250-253 ◽  
Author(s):  
Deepak Dwivedi ◽  
Veerendra Singh ◽  
Jyoti Singh ◽  
Sangita Sharma

Introduction: Severe anaemia is a leading cause of paediatric morbidity, hospitalization, and mortality and it is very important co morbidity in children with severe acute malnutrition. Severe Acute Malnutrition (SAM) with anaemia has been shown to have 2.62 times higher mortality as compared to SAM with no anaemia. So this study was done to evaluate this co-morbidity further. The aim of present study was to determine the prevalence and type of anaemia and to evaluate the possible aetiologies of anaemia in severe acute malnourished (SAM) children.Material and Methods: In tertiary care hospital a cross sectional study was conducted over a period of 8 month with 100 cases of SAM children and 101 cases of normal children. In both cases disorders of primary haematological problem were excluded. Auto analysers were used to measure blood counts. Blood smear was analysed by pathology consultant of institute and recorded for all patients with anaemia. Grade of anaemia and morphologic type of anaemia was analysed. Data were entered in Excel spreadsheets and analysed using SPSS 20.0.Results: Patient with SAM 42% had moderate anaemia and 19% had severe anaemia in contrast 41.6% and 16.8% in NON SAM child respectively. Predominant morphologic type in SAM patient was macrocytic anaemia (33%), while in controls microcytic anaemia (40.6%) was more prevalent.Conclusion: There was a high prevalence of anaemia in SAM children. Major morphologic type in SAM children was macrocytic anaemia which may indirectly show vitamin B12 or folic acid deficiency in these children.  


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