scholarly journals Prevalence and associated risk factors of abnormal Pap smear in pregnant women

Author(s):  
Meenakshi Venkatesh ◽  
Ushadevi .

Mohindroo N et al, conducted a prospective study  about the prevalence and risk factors associated with abnormal pap smear in pregnant women.1 This study is in need of the hour because carcinoma cervix is on increasing trend due to multiple sexual partners, HPV infection, and use of OCP in young women lead in increase in adenocarcinoma of cervix.2 Indian women face a 2.5% cumulative lifetime risk and 1.4% cumulative death risk from cervical cancer.1

Author(s):  
Neha Mohindroo ◽  
Anoop Sharma ◽  
Santosh Minhas ◽  
Kushla Pathania

Background: The Papanicolaou test is a method of cervical screening used to detect pre-cancerous and cancerous processes. The incidence of cervical cancer in India is alarmingly high and is the leading cause of cancer in women in India accounting for 147 deaths per lakh women. Cervical cytological abnormalities are found in up to 5% of all pregnancies. In Indian settings, published data on abnormal Pap smear in pregnancy is lacking. The present study was designed to know the prevalence of abnormal Pap smear in pregnant women and its associated risk factors.Methods: This prospective study included 450 pregnant and 450 non-pregnant women who fulfilled the inclusion criteria. After a detailed history, clinical examination and investigations, Pap smear was collected as per conventional method and reported using 2014 Bethesda system.Results: 53.6% pregnant and 44.6% non-pregnant subjects had abnormal Pap smear. Out of the abnormal smears in pregnant women, 31.18% had inflammatory cytology, 15.37% had bacterial vaginosis, 4.01% had Trichomonal and 3.34% Monilial pathology. No epithelial cell abnormality was seen. Rural residence, lower class, age at first intercourse less than 21 years and having more than one sexual partner were important risk factors observed in our study and were statistically significant.Conclusions: Bacterial vaginosis, the most common infection detected on Pap smear is strongly associated with previos preterm labour and delivery. This opportunity for screening of cervical cancer and counselling should not be missed in the antenatal period.


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Anteneh Amsalu ◽  
Getachew Ferede ◽  
Setegn Eshetie ◽  
Agete Tadewos ◽  
Demissie Assegu

Background. Hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) positive mother has up to 90% likelihood of mother-to-child transmission (MTCT) of hepatitis B virus (HBV) to newborns in the absence of any prophylaxis or antiviral therapy utilization. However, routine antenatal screening and intervention strategies are not yet practiced in Ethiopia. Therefore, this study was conducted to determine the prevalence, infectivity, and associated risk factors of HBV among pregnant women. Methods. A cross-sectional study was conducted from October 2015 to August 2016 in Yirgalem Hospital. A total of 475 pregnant women were recruited, and data on sociodemography and potential risk factors were collected using a structured questionnaire. In addition, blood samples were tested for HBsAg, and HBsAg positive samples were retested for HBeAg using commercially available strip test. The status of HIV was collected from the records. Results. The seroprevalence of HBsAg was 34 (7.2%), of whom 13 (38.8%) were positive for HBeAg. The prevalence of HIV infection was 10.1% (48/475). Ten out of 34 HBV positive cases (29.4%) were coinfected with HIV. The overall HBV/HIV coinfection rate was 2.1% (10/475). Women with history of multiple sexual partners and being HIV positive were significantly associated with HBsAg positivity. Among the study participants, 35.4% were aware of MTCT of HBV and only 12 (2.5%) have taken HBV vaccine. Conclusions. High prevalence of HBsAg and HBeAg as well as low awareness and practices of HBV prevention methods suggests that perinatal transmission of HBV might be the prevailing mode of HBV transmission in the study area. Thus, screening of all pregnant women, particularly those who had history of multiple sexual partners and HIV coinfection, and provision of health education about HBV prevention methods are inevitable.


2020 ◽  
Vol 4 (3) ◽  
pp. 645-655
Author(s):  
OLOBO F. AWULU ◽  
Mariam Aminu ◽  
A. B. SULEIMAN ◽  
DANIEL MAKOLO

Analysis of prevalence and risk factors for Human Papilloma Virus (HPV) is the basis for prophylactic strategies against HPV infections. This study was to determine the seroprevalence of human papillomavirus, sociodemographic and risk factors associated with acquiring the virus among the study population. A total of 195 samples were collected by simple random sampling technique from three major hospitals in the zone. Serum from blood samples was used for ELISA and analyzed for IgM. Overall prevalence of 3.08% (6/195) was established for HPV infection. Patients with early sexual activity and those with multiple sexual partners were likely to be infected than their counterparts with 15.8%: 3/19 (χ 2 =16.4, df=3, p=0.001) and 50%: 2/4 (χ 2 =30.2, df=1, p=0.005) respectively. The infection was more among those who got married at age range of 26-30 years with prevalence of 5.4%: 2/37 (χ 2 =1.30, df = 5, p=0.82). On the basis of sex, female were found to have higher prevalence of 3.6%: 6/167(χ 2 =1.04, df = 1, p=0.6). Subjects with sexually transmitted disease (STD) had a higher prevalence of 8%: 2/25(χ 2 =2.45, df=2, p=0.32). The study shows that infection with HPV was strongly associated with age of sexual debut and number of sexual partners. It also reveals the occurrence of HPV infection in Kogi East, Nigeria. Hence, there is need for routine screening, public education and vaccination to prevent the spread of the virus which is a threat to public health.


Author(s):  
Christopher E. Ekpenyong ◽  
Nsikak E. Udokang ◽  
Comfort A. Inyang

Background: Despite available evidences that pregnant women are specific vulnerable target population for dehydration and the importance of adequate hydration to both the mother and the developing fetus, studies assessing the prevalence and associated risk factors of dehydration among pregnant women are limited. Aim: The aim of the present study was to determine the prevalence and associated risk factors of dehydration among pregnant women in Uyo metropolis, Southern Nigeria. Methods: A total of 316 pregnant women from selected obstetric centers in Uyo Metropolis met the inclusion criteria and were evaluated for socio-demographics, lifestyle-related behaviors and urinary specific gravity using standard instruments. Mean values were calculated and used for the determination of the hydration status of the participants. Univariate analysis was used to assess the relationship between socio-demographic variables and lifestyle related behaviours and prevalence of dehydration. Multiple logistic regression analysis was used to determine odds ratios (ORs) and 95% confidence interval for factors associated with dehydration in pregnancy. Results: About 14.6% of the pregnant women were dehydrated, and factors associated with high prevalence of dehydration were age between 26 and 35 years, being married, urban residence, acquiring a tertiary education and income between 20,000 and 50,000 naira. Others were, null-parity, third trimester of pregnancy, physically active, poor dietary habits, alcohol consumption, inadequate water intake and short sleep duration. Inadequate water intake (1-2 cups of water) (OR=6.10,C.I=2.029-18.360) or 5-7cups of water (OR=4.04,C.I=1.385-11.785), consumption of mostly high carbohydrate diets (OR=3.55,C.I=1.003-12577), consumption of mostly high protein diets (OR=3.25,C.I=1.893-11.844) and craving for strange foods(OR=3.71, C.I=1.563-8.81) significantly increased the odds for dehydration among the participants. Conclusion: Demographic, obstetric and lifestyle-related factors drive the high prevalence of dehydration among pregnant women and should be considered in designing intervention programs to prevent dehydration among pregnant women in our communities.     


2015 ◽  
Vol 21 (1) ◽  
pp. 140-148 ◽  
Author(s):  
Yeny Z. Castellanos‐Domínguez ◽  
Zulma M. Cucunubá ◽  
Luis C. Orozco ◽  
Carlos A. Valencia‐Hernández ◽  
Cielo M. León ◽  
...  

GYNECOLOGY ◽  
2020 ◽  
Vol 22 (6) ◽  
pp. 74-79
Author(s):  
Tamara N. Bebneva ◽  
Galina B. Dikke

Aim. To determine the risk factors for human papillomavirus of high carcinogenic risk (HPV HCR) and cervical diseases (CD) in pregnant women associated with the social status, reproductive and contraceptive behavior. Materials and methods. Design: open-label comparative non-interventional cohort study in parallel groups. The total number of patients 330 people, of whom 148 women were negative for HPV and 182 women were positive. They were divided into 4 groups depending on the presence or absence of CD. Methods: analysis of anamnesis data, general clinical, test Kvant-21 to determine HPV, cytological examination, extended colposcopy. Results. The most significant risk factors for HPV HRS infection were identified: history of mycoplasma infection (OR 5.9) and BV (OR 5.3), alcohol consumption (OR 4.0). A history of STIs (trichomoniasis and chlamydial infection), as well as more than 3 sexual partners (OR 2.7) were also significant. The most significant risk factors for CD in HPV-infected women were: age over 35 years (OR 3.8), a history of bacterial vaginosis (OR 3.0), and lack of regular screening (OR 2.4). The coitarche earlier than 16 years old (OR 2.2) also mattered. There were also found factors indicating a low risk of HPV infection the use of condoms (OR 0.3), and a low risk of CD was indicated by age under 25 years (OR 0.2) and regular screening (OR 0.3). Conclusion. HPV infection with HRS and the prevalence of CMC in pregnant women against the background of HPV infection is associated mainly with social risk factors, to a lesser extent with factors of reproductive and contraceptive behavior.


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