scholarly journals SEROPREVALENCE AND RISK FACTORS ASSOCIATED WITH HPV INFECTIONS AMONG PATIENTS IN KOGI EAST SENATORIAL ZONE

2020 ◽  
Vol 4 (3) ◽  
pp. 645-655
Author(s):  
OLOBO F. AWULU ◽  
Mariam Aminu ◽  
A. B. SULEIMAN ◽  
DANIEL MAKOLO
Keyword(s):  
Risk Factors ◽  
Sexual Debut ◽  
Transmitted Disease ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
Hpv Infection ◽  
Sexual Partners ◽  
Multiple Sexual Partners ◽  
Sexually Transmitted ◽  
Factors Associated

Analysis of prevalence and risk factors for Human Papilloma Virus (HPV) is the basis for prophylactic strategies against HPV infections. This study was to determine the seroprevalence of human papillomavirus, sociodemographic and risk factors associated with acquiring the virus among the study population. A total of 195 samples were collected by simple random sampling technique from three major hospitals in the zone. Serum from blood samples was used for ELISA and analyzed for IgM. Overall prevalence of 3.08% (6/195) was established for HPV infection. Patients with early sexual activity and those with multiple sexual partners were likely to be infected than their counterparts with 15.8%: 3/19 (χ 2 =16.4, df=3, p=0.001) and 50%: 2/4 (χ 2 =30.2, df=1, p=0.005) respectively. The infection was more among those who got married at age range of 26-30 years with prevalence of 5.4%: 2/37 (χ 2 =1.30, df = 5, p=0.82). On the basis of sex, female were found to have higher prevalence of 3.6%: 6/167(χ 2 =1.04, df = 1, p=0.6). Subjects with sexually transmitted disease (STD) had a higher prevalence of 8%: 2/25(χ 2 =2.45, df=2, p=0.32). The study shows that infection with HPV was strongly associated with age of sexual debut and number of sexual partners. It also reveals the occurrence of HPV infection in Kogi East, Nigeria. Hence, there is need for routine screening, public education and vaccination to prevent the spread of the virus which is a threat to public health.

scholarly journals 945. Prevalence of HIV Associated Non-AIDS Conditions and Associated Risk Factors among Hospitalized HIV-infected Patients in India

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S504-S505
Author(s):  
Amyeo A Jereen ◽  
Celia Kucera ◽  
Saniya Pervin ◽  
Muralidhar Varma ◽  
Radhakrishnan Rajesh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Transmitted Disease ◽  
Multivariate Logistic Regression Analysis ◽  
Patient Risk ◽  
Sexually Transmitted ◽  
Factors Associated ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Artery Disease ◽  
Associated Risk Factors

Abstract Background HIV-associated non-AIDS (HANA) conditions are becoming common as People Living with Human Immunodeficiency Virus (PLWHIV) age. However, data estimating the prevalence of HANA conditions and associated risk factors is lacking in developing countries. This study evaluates reasons for hospitalizations among PLWHIV in Udupi, India in the antiretroviral era, and describes associated risk factors. Methods Demographic and clinical data were extracted from medical charts of 1280 HIV-infected patients 18 years and older who were admitted to Kasturba Hospital, Manipal, India between January 1, 2013 and December 31, 2017, for a total of 2157 hospitalizations. Primary reasons for hospitalization were categorized into AIDS-defining vs Non-AIDS-defining and HANA vs Non-HANA conditions (Fig 1). Multivariate logistic regression analysis was performed to estimate demographic and clinical factors associated with hospitalizations due to AIDS-defining illness and HANA conditions. Categorization of Reasons for Hospitalization Results Patients’ median age was 45 (18-80) years; 70% male. Median age of patients with AIDS-defining illness (45% of hospitalizations) was lower at 44 (18-75) years compared with HANA (15% of hospitalizations) at 48 (21-80) years. Age (OR, 95% CI) (0.985, 0.974-0.995), admission CD4 (0.998, 0.997 - 0.998), history of hypertension (HTN) (0.59, 0.42-0.82), stroke (0.49, 0.24 - 0.93), diabetes (1.56, 1.10 - 2.19), and AIDS-defining cancers (1.74, 1.05 - 2.89) were associated with AIDS-defining hospitalizations (Fig 2). Additionally, age (1.016, 1.001 - 1.031), history of HTN (1.70, 1.16 - 2.46), coronary artery disease (CAD) (4.02, 1.87- 9.02), chronic kidney disease (CKD) (2.30, 1.15 - 4.61), stroke (2.93, 1.46 - 5.96), Hepatitis B (3.32, 1.66- 6.72), Hepatitis C (16.1, 2.84 - 314), sexually transmitted disease (STD) (3.76, 1.38- 10.8), and HANA-associated cancer (2.44, 1.28- 6.42) were associated with HANA hospitalizations (Fig 3). Patient Risk Factors for AIDS-related Hospitalization Patient Risk Factors for HANA-related Hospitalization Conclusion Prevalence of HANA conditions was lower than AIDS-defining illnesses possibly because of a younger population. Patients with AIDS-defining illnesses were also likely to have HANA conditions. Early detection and effective treatment of both HIV and HANA conditions is essential to decrease hospitalizations in low-resource settings. Disclosures All Authors: No reported disclosures

Risk factors associated with human papillomavirus infection status in a Korean cohort

2013 ◽  
Vol 142 (8) ◽  
pp. 1579-1589 ◽  
Author(s):  
H. LEE ◽  
D.-H. LEE ◽  
Y.-M. SONG ◽  
K. LEE ◽  
J. SUNG ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Contraceptive Use ◽  
Transmitted Disease ◽  
Multivariate Regression Analysis ◽  
Hpv Infection ◽  
Sexually Transmitted ◽  
Papillomavirus Infection ◽  
Behavioural Factors ◽  
Epidemiological Characteristics

SUMMARYBy surveying extensive epidemiological behavioural and sexual risk factors in a Korean twin cohort, risk factors for human papillomavirus (HPV) infection were investigated in South Korea. A total of 912 vaginal specimens were collected from the Healthy Twin Study, consisting of twins and their families. A range of epidemiological, behavioural, and sexual activity characteristics were evaluated using multivariate logistic regression analyses of family and twin relationships, adjusted to elucidate the risk factors for HPV infection. Of the various epidemiological characteristics, the possibility of extramarital affairs [odds ratio (OR) 2·48, 95% confidence interval (CI) 1·02–6·02] significantly increased the prevalence of HPV infection. Our multivariate regression analysis indicated that oral contraceptive use (OR 40·64, 95% CI 0·99–1670·7) and history of sexually transmitted disease (OR 2·56, 95% CI 0·93–7·10) were strongly associated with an increase in HPV infection. On the other hand, more frequent vaginal douching (OR 0·32, 95% CI 0·13–0·77) significantly decreased the prevalence of HPV infection. Our results suggested that HPV infection is associated with both biological and behavioural factors.

scholarly journals Epidemiology of ectopic pregnancy at Laquintinie Douala hospital (Cameroon): prevalence survey, clinical profile, therapeutic and transfusion issues

2020 ◽  
Vol 10 (1) ◽  
pp. 44
Author(s):  
Henri Essome ◽  
Thomas O. Egbe ◽  
Gregory E. Halle ◽  
Théophile N. Nana ◽  
Merlin Boten ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ectopic Pregnancy ◽  
First Trimester ◽  
Sexual Partners ◽  
Age Group ◽  
Prevalence Survey ◽  
Multiple Sexual Partners ◽  
Sexually Transmitted ◽  
First Trimester Of Pregnancy ◽  
Therapeutic Profile

Background: Pregnancy is a serious pathology of the first trimester of pregnancy and is the leading cause of death. The objective of our work was to determine the hospital prevalence of ectopic pregnancy (EP), to describe the epidemiological, clinical and therapeutic profile given the often-haemorrhagic context at Laquintinie Hospital in Douala.Methods: We carried out a retrospective study over 10 years, from January 1st, 2007 to December 31st, 2016, using the operating theatre registers and the files of patients admitted during this period for ectopic pregnancy in the gynaecology and obstetrics department of the Laquintinie Hospital in Douala.Results: A total of 905 cases of EP for 32,595 deliveries were recorded, for an overall incidence of 2.8%. EP mainly affected the age group of 25 to 35 (60.6%), single people (57.9%) and housewives (46.6%). The risk factors found were similar to those of cervical cancer, namely multiple sexual partners (80.4%), the precocity of sexual intercourse under 18 years (54.1%) and sexually transmitted infections (52.5%). The symptomatic triad (pelvic pain, amenorrhea and metrorrhagia) was found in 46.1% of cases with a respective order of frequency of 96.9%, 77.3% and 63.6% The management was essentially surgical by radical laparotomy (97% of cases). Two of the 07 deaths were due to religious considerations.Conclusions: EP remains a frequent pathology in our environment with a heavy toll of tubal amputations and death.

Quadrivalent human papillomavirus vaccination successfully reduces the prevalence of vaccine-targeted genotypes in a young, vaccine-eligible-age sample of Australian females

Sexual Health ◽  
2020 ◽  
Vol 17 (6) ◽  
pp. 510
Author(s):  
Asvini K. Subasinghe ◽  
John D. Wark ◽  
Samuel Phillips ◽  
Alyssa Cornall ◽  
Julia M. L. Brotherton ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Sexual Debut ◽  
Hpv Vaccination ◽  
Sexual Partners ◽  
Vaccination Status ◽  
Vaccine Uptake ◽  
Early Sexual Debut ◽  
Multiple Sexual Partners ◽  
Hpv Dna ◽  
Factors Associated

Background The prevalence of genital tract vaccine-type human papillomavirus (HPV) is on the decline due to high vaccine uptake through the national HPV immunisation program in Australia. The aim of this study was to investigate HPV vaccine coverage and factors associated with HPV in a vaccine-eligible sample of young Australian females. Methods: Females aged 16–25 years were recruited into the Young Female Health Initiative study, a young women’s health study, via Facebook advertising from 2012 to 2017. Sexually active participants were asked to provide a self-collected vaginal swab for the detection of HPV DNA; positive samples were genotyped. Self-reported HPV vaccination status was confirmed by the National HPV Vaccination Program Register. Outcomes of the study were HPV acquisition and genotype, HPV vaccination status and factors associated with HPV. Results: Overall, 22.8% of samples (95% confidence interval (CI) 17.8–27.8%; n = 62/272) were positive for any HPV DNA, of which 19.1% (95% CI 14.4–23.8%; n = 52/272) were oncogenic types. HPV 16 was detected in three samples (1.1%; 95% CI –0.1%, 2.3%; two not HPV vaccinated and one vaccinated after sexual debut). Early sexual debut (<16 years) and multiple sexual partners were independently associated with an increased risk of any HPV. Conclusions: In a community sample of vaccine-eligible-age females with a high vaccine uptake, the prevalence of vaccine-related HPV genotypes is extremely low. Early sexual debut and multiple sexual partners are positively associated with HPV, underscoring the importance of vaccination at the routinely recommended age of 12–13 years for best vaccine impact.

scholarly journals Prevalence and associated risk factors of abnormal Pap smear in pregnant women

2020 ◽  
Vol 9 (6) ◽  
pp. 2673
Author(s):  
Meenakshi Venkatesh ◽  
Ushadevi .
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Pap Smear ◽  
Hpv Infection ◽  
Indian Women ◽  
Multiple Sexual Partners ◽  
Factors Associated ◽  
Increasing Trend ◽  
Associated Risk Factors ◽  
A Prospective Study

Mohindroo N et al, conducted a prospective study  about the prevalence and risk factors associated with abnormal pap smear in pregnant women.1 This study is in need of the hour because carcinoma cervix is on increasing trend due to multiple sexual partners, HPV infection, and use of OCP in young women lead in increase in adenocarcinoma of cervix.2 Indian women face a 2.5% cumulative lifetime risk and 1.4% cumulative death risk from cervical cancer.1

Intimate partner violence and factors associated with sexually transmitted infections among Thai women attending gynecology clinics

2020 ◽  
pp. 095646242096613
Author(s):  
Nanthana Thananowan ◽  
Nopporn Vongsirimas ◽  
Porntip Rachapromma
Keyword(s):  
Intimate Partner Violence ◽  
Alcohol Use ◽  
Sexually Transmitted Infections ◽  
Partner Violence ◽  
Intimate Partner ◽  
Sexual Partners ◽  
Thai Women ◽  
Multiple Sexual Partners ◽  
Sexually Transmitted ◽  
Factors Associated

Intimate partner violence (IPV) and sexually transmitted infections (STIs) are significant public health problems worldwide. However, most research on this association and risk of STIs has been conducted in Western countries and may not be generalizable to women living in different contexts, such as Thailand. We aimed to examine prevalence of IPV and identify factors associated with STIs among Thai women. Participants were patients aged 15–49 years attending two gynecology clinics at a university hospital in Bangkok, Thailand. Data were collected through an anonymous structured questionnaire, including sociodemographic characteristics, IPV, childhood abuse (CA), sexual risk behaviors, alcohol use, depressive symptoms, and self-reported STI diagnosis. Multivariate logistic regression analyses were used to examine factors associated with STI diagnosis. Among 400 participants, 84 (21%) had ever experienced at least one type of IPV in the past year. IPV, CA, age at first sex, multiple sexual partners, and alcohol use were significantly associated with STI-positive. Women who reported IPV (OR = 2.65, 95% CI = 1.11–6.28), experienced CA (OR = 5.59, 95% CI = 1.08–28.99), and had multiple sexual partners (OR = 1.39, 95% CI = 1.08–1.79) were significantly more likely to have an STI. Incorporation of IPV screening into general STIs screening is needed for this population to prevent and decrease IPV and STI consequences. Further research is also needed to understand the pathways linking IPV and STI risk to optimize the design of effective prevention interventions.

scholarly journals Hydrolyzed FB1 (aminopentol) detection on urine of HPV positive Mexican women: A preliminary study

2021 ◽  
Author(s):  
M. Ángeles Ramírez-Cisneros ◽  
Vladimir Rivera ◽  
Maria Yolanda Rios ◽  
Cruz Vargas-De-León ◽  
Sonia Dávila ◽  
...  
Keyword(s):  
Transmitted Disease ◽  
Healthy Woman ◽  
Fumonisin B1 ◽  
Hpv Infection ◽  
Multiple Sexual Partners ◽  
Sexually Transmitted ◽  
Surface Receptors ◽  
Preliminary Study ◽  
Main Component ◽  
Membrane Components

Abstract Human Papillomavirus (HPV) infection is the most common sexually transmitted disease in humans. About 200 HPV types have been described and classified into high and low oncogenic risk for its ability to transform the cell. Some main risk factors for HPV infection are multiple sexual partners, multiparity and immunosuppression. However, these factors can not completely explain the HPV prevalence in different world regions. Mexico has a high global burden, being important to determine other external biological factors implicated. The infection is mediated by surface receptors of basal stratum cells that bind to the viral capsid entering the cell by endocytosis. Some cell membrane components such as sphingolipids have a role in structure and membrane permeability. Besides, fumonisins are micotoxins structurally very similar to sphingolipids, fumonisin B1 (FB1) is the most abundant and most similar to some sphingolipids such ceramide. Fumonisins are produced by Fusarium fungus, widely distributed in maize, the main component of Mexican diet. Thus, it is possible that FB1 contamination be a factor to permeabilize the membrane expediting the HPV infection. In this preliminary study, we postulated that mechanism of HPV infection is mediated by contamination with FB1, hence, FB1 could be higher in women HPV positive. Urine samples from patients with HPV infection and healthy woman were analyzed by UPLC-MS, hydrolyzed FB1 was found only in the infected women, in contrast, in HPV negative women was not detected. Additional studies are needed to support the hypothesis of contamination with FB1 as biological risk factor for HPV infection.

Sexual risk behaviour among young people in Osogbo, Osun state Nigeria

2005 ◽  
Vol 35 (4) ◽  
pp. 213-215 ◽  
Author(s):  
V O Mabayoje ◽  
P O Akinwusi ◽  
S O Fadiora ◽  
O A Adeyeba ◽  
A O Aderounmu ◽  
...  
Keyword(s):  
Young People ◽  
Sexual Risk ◽  
Sex Education ◽  
Transmitted Disease ◽  
Risk Behaviour ◽  
Sexual Partners ◽  
Sexual Risk Behaviour ◽  
Multiple Sexual Partners ◽  
Sexually Transmitted ◽  
The Mean

By analysing data randomly collected via administration of questionnaire by interview of individuals on sexual risk behaviour to 628 young people living in Osogbo, Nigeria, the results of the questionnaire revealed that the mean age of first sexual encounter was 17.4 years for men and 16.5 years for women. Men tended to have multiple sexual partners more than the women (74.4% and 25.1%, respectively), while there was a highly significant relationship between sexually transmitted disease and multiple sexual partners among singles with P<0.001 and P= 0.000. We concluded that parents and government alike should teach sex education at home, and in schools involving intensive counselling.

scholarly journals Seroprevalence and Risk Factors Associated with Human Immunodeficiency Virus Infection Type 1 in Donors of the National Blood Transfusion Center of Libreville (Gabon)

2021 ◽  
pp. 16-24
Author(s):  
Christian Mangala ◽  
Therese Nkoa ◽  
Denis Maulot-Bangola ◽  
Franck Vivien Vigan Codjo ◽  
Joseph Fokam
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Dental Care ◽  
Blood Donors ◽  
Sexual Partners ◽  
Multiple Sexual Partners ◽  
Factors Associated ◽  
Transfusion Center ◽  
Blood Transfusion Center ◽  
Hiv 1

Background: Transmission of HIV through blood transfusion remains a public health problem, particularly in countries in Sub-Saharan Africa. However, no study has determined the epidemiological data regarding HIV-1 infection in Gabonese blood donors. The objective of this study is to assess the seroprevalence of HIV-1 and the risk factors associated with infection in donors from the National Blood Transfusion Center in Libreville (Gabon). Methods: A cross-sectional study carried out from June to August 2020 in 3669 persons donating blood at the National Blood Transfusion Center (NBTC). The ELISA technique (Evolis®, BioRad), the chemiluminescence technique (Cobas® e601, Roche), and the SD Bioline® HIV 1/2 test (Standard Diagnostics. Inc) were used for the detection of anti-HIV-1/2 antibodies and P24 antigen in donor plasma. Data were analyzed using SPSS software version 21.0, with p˂.05 considered statistically significant.  Results: The seropositivity rate HIV-1 was 0.8% (30/3669) (95% CI: 0.5; 1.1). The study was composed of 79.4% men and 20.6% women. The most representative age group was of 25-34 years with 54.5%. The seropositivity of men, women, and unrelated voluntary donors was 0.7%, 1.2%, and 1.0%, respectively. The risk factors such as the first blood donation (Adjusted Odds Ratio (AOR) = 0.1 [0.0 ;0.4], P= .002), multiple sexual partners (AOR = 6.2 [2.2;17.2], P= .001), primary educational level (AOR = 10.1 [1.4;75], P = .024), and dental care (AOR = 3.6 [1.2;11], P = .024) were significantly associated with HIV infection. About 0.14% of the patients had co-infection. Conclusion: In the Gabonese context, about one out of a hundred blood donors are HIV-infected. These carriers of HIV infection in the blood banks are mainly new donors with multiple sexual partners, limited education, and poor dental care.

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