scholarly journals Chubby mothers-maternal and perinatal outcome in high body mass index

Author(s):  
Kavitha Garikapati ◽  
K. B. Gayathri ◽  
K. Naga Lalitha

Background: Obesity is a state of excess adipose tissue mass. Body mass index (BMI) is a crucial predictor of nutritional status of pregnant women. High BMI may lead to various adverse maternal and perinatal outcomes. This study is designed to see the effect of maternal BMI on pregnancy outcome and perinatal outcome according to Asian standards.Methods: This is an institutional retrospective, descriptive study of 100 pregnant women conducted in the department of obstetrics and gynaecology of a rural tertiary centre Dr. PSIMS and RF, Chinaoutpalli, Gannavaram, Vijayawada, AP, India from June 2017 to July 2019.Results: It was observed that as BMI increased risk of complications increased like hypertension disorders in pregnancy, gestational diabetes mellitus, preterm labour. Also risk of macrosomia, operative delivery, Neonatal intensive care unit (NICU) admissions increased.Conclusions: As maternal BMI is a good predictor has strong correlation with pregnancy complications and outcomes, measures should be taken to motivate for pre pregnancy counselling regarding weight management and close surveillance in antenatal period to diagnose at the earliest any complications.

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 194s-194s ◽  
Author(s):  
R. Carey ◽  
R. Norman ◽  
D. Whiteman ◽  
A. Reid ◽  
R. Neale ◽  
...  

Background: High body mass index (BMI > 25 kg/m2) has been found to be associated with an increased risk of many cancers, including cancers of the colon and rectum, liver, and pancreas. Aim: This study aimed to estimate the future burden of cancer resulting from current levels of overweight and obesity in Australia. Methods: The future excess fraction method was used to estimate the future burden of cancer among the proportion of the Australian adult population who were overweight or obese in 2016. Calculations were conducted for 13 cancer types, including cancers of the colon, rectum, kidney, and liver. Results: The cohort of 18.7 million adult Australians in 2016 will develop ∼7.6 million cancers over their lifetime. Of these, ∼402,500 cancers (5.3%) will be attributable to current levels of overweight and obese. The majority of these will be postmenopausal breast cancers (n = 72,300), kidney cancers (n = 59,200), and colon cancers (n = 55,100). More than a quarter of future endometrial cancers (30.3%) and esophageal adenocarcinomas (35.8%) will be attributable to high body mass index. Conclusion: A significant proportion of future cancers will result from current levels of high body mass index. Our estimates are not directly comparable to past estimates of the burden from overweight and obesity because they describe different quantities - future cancers in currently exposed vs current cancers due to past exposures. The results of this study provide us with relevant up-to-date information about how many cancers in Australia could be prevented.


2018 ◽  
Vol 25 (15) ◽  
pp. 1646-1652 ◽  
Author(s):  
Lars E Garnvik ◽  
Vegard Malmo ◽  
Imre Janszky ◽  
Ulrik Wisløff ◽  
Jan P Loennechen ◽  
...  

Background Atrial fibrillation is the most common heart rhythm disorder, and high body mass index is a well-established risk factor for atrial fibrillation. The objective of this study was to examine the associations of physical activity and body mass index and risk of atrial fibrillation, and the modifying role of physical activity on the association between body mass index and atrial fibrillation. Design The design was a prospective cohort study. Methods This study followed 43,602 men and women from the HUNT3 study in 2006–2008 until first atrial fibrillation diagnosis or end of follow-up in 2015. Atrial fibrillation diagnoses were collected from hospital registers and validated by medical doctors. Cox proportional hazard regression analysis was performed to assess the association between physical activity, body mass index and atrial fibrillation. Results During a mean follow-up of 8.1 years (352,770 person-years), 1459 cases of atrial fibrillation were detected (4.1 events per 1000 person-years). Increasing levels of physical activity were associated with gradually lower risk of atrial fibrillation ( p trend 0.069). Overweight and obesity were associated with an 18% (hazard ratio 1.18, 95% confidence interval 1.03–1.35) and 59% (hazard ratio 1.59, 95% confidence interval 1.37–1.84) increased risk of atrial fibrillation, respectively. High levels of physical activity attenuated some of the higher atrial fibrillation risk in obese individuals (hazard ratio 1.53, 95% confidence interval 1.03–2.28 in active and 1.96, 95% confidence interval 1.44–2.67 in inactive) compared to normal weight active individuals. Conclusion Overweight and obesity were associated with increased risk of atrial fibrillation. Physical activity offsets some, but not all, atrial fibrillation risk associated with obesity.


2017 ◽  
Vol 1 (24) ◽  
pp. 2186-2192 ◽  
Author(s):  
Marianna Thordardottir ◽  
Ebba K. Lindqvist ◽  
Sigrun H. Lund ◽  
Rene Costello ◽  
Debra Burton ◽  
...  

Key PointsObesity is not associated with MGUS or LC-MGUS. High body mass index during midlife is associated with increased risk of progressing from MGUS and LC-MGUS to MM and other LP diseases.


2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e15066-e15066
Author(s):  
Younak Choi ◽  
Do-Youn Oh ◽  
Tae-Yong Kim ◽  
Kyung-Hun Lee ◽  
Sae-Won Han ◽  
...  

e15066 Background: The obesity is increasing worldwide. High body mass index (BMI) is linked with an increased risk of developing pancreatic cancer (PC). However, in patients with advanced PC (APC), especially those are receiving palliative chemotherapy (the majority of all PC patients), the impact of BMI and its change during disease course on survival has not been fully investigated. Methods: Consecutive patients with APC were enrolled during years 2003-2010, all treated with palliative chemotherapy. The BMI measured at the point of starting the first cycle of palliative chemotherapy was called as “BMI at diagnosis”. “Pre-cancer weight” which means the weight in good health was the sum of “weight at diagnosis” and “weight loss at diagnosis” that the patients’ self- reported at the first visit. “Pre-cancer BMI” was calculated using pre-cancer weight. We got weight data measured at every visit during chemotherapy to investigate BMI change during chemotherapy period. Clinical characteristics and outcomes were analyzed. Results: A total of 425 patients were enrolled (median age, 60.1 years). At diagnosis of APC, the BMI distribution of patients was as follows: <18.5 (45, 10.6%); 18.5-19.9 (67, 15.8%); 20.0-22.4 (156, 36.7%); 22.5-24.9 (107, 25.2%); 25.0-29.9 (49, 11.5%); and ≥30.0 (1, 0.2%). Clinical characteristics were balanced across BMI groups. Median overall survival (OS) was 8.1 months (95% CI, 7.2-9.1). Pre-cancer BMI and BMI at diagnosis had no impact on OS (p = 0.488, p = 0.348, respectively), although patients at BMI range of 22.5-24.9 achieved the longest OS (9.9 months; 95% CI, 8.5-11.3). BMI loss at diagnosis (pre-cancer BMI minus BMI at the diagnosis) and BMI loss during chemotherapy (both stipulated as BMI change ≥1) were associated with shortened OS (HR, 1.300; p = 0.012 and HR, 1.367; p= 0.010, respectively). Conclusions: In patients with APC undergoing palliative chemotherapy, both declines in BMI at diagnosis of APC and during chemotherapy are more hazardous for OS than pre-cancer BMI or BMI at diagnosis itself as absolute values. Further research evaluating strategies to maintain BMI during chemotherapy in this setting is thus warranted.


2017 ◽  
Vol 30 (13) ◽  
pp. 1574-1578 ◽  
Author(s):  
Hatice Kansu-Celik ◽  
Burcu Kisa Karakaya ◽  
Ali Irfan Guzel ◽  
Yasemin Tasci ◽  
Salim Erkaya

2007 ◽  
Vol 35 (8) ◽  
pp. 1289-1294 ◽  
Author(s):  
Malachy P. McHugh ◽  
Timothy F. Tyler ◽  
Michael R. Mirabella ◽  
Michael J. Mullaney ◽  
Stephen J. Nicholas

Background A high body mass index and previous ankle sprains have been shown to increase the risk of sustaining noncontact inversion ankle sprains in high school football players. Hypothesis Stability pad balance training reduces the incidence of noncontact inversion ankle sprains in football players with increased risk. Study Design Cohort study; Level of evidence, 2. Methods Height, body mass, history of previous ankle sprains, and current ankle brace/tape use were documented at the beginning of preseason training in 2 high school varsity football teams for 3 consecutive years (175 player-seasons). Players were categorized as minimal risk, low risk, moderate risk, and high risk based on the history of previous ankle sprain and body mass index. Players in the low-, moderate-, and high-risk groups (ie, any player with a high body mass index and/or a previous ankle sprain) were placed on a balance training intervention on a foam stability pad. Players balanced for 5 minutes on each leg, 5 days per week, for 4 weeks in preseason and twice per week during the season. Postintervention injury incidence was compared with preintervention incidence (107 players-seasons) for players with increased risk. Results Injury incidence for players with increased risk was 2.2 injuries per 1000 exposures (95% confidence interval, 1.1-3.8) before the intervention and 0.5 (95% confidence interval, 0.2-1.3) after the intervention (P < .01). This represents a 77% reduction in injury incidence (95% confidence interval, 31%-92%). Conclusion The increased risk of a noncontact inversion ankle sprain associated with a high body mass index and a previous ankle sprain was eliminated by the balance training intervention.


2016 ◽  
Vol 9 (3) ◽  
pp. 120-125 ◽  
Author(s):  
Sarah R Chwah ◽  
Amanda Reilly ◽  
Beverley Hall ◽  
Anthony J O’Sullivan ◽  
Amanda Henry

Aims To compare pregnancy care, maternal and neonatal outcomes of women with Body Mass Index (BMI) >30 enrolled in a Weight Intervention Group versus other models of antenatal care. Methods Retrospective, case-control study of mothers with BMI >30 managed with a specialised programme versus age-matched women enrolled in standard models of care. Results One thousand, one hundred and fifteen of 9954 pregnant women with singleton pregnancies, had a BMI >30, of whom 9.6% enrolled in the intervention group. Compared to controls, the intervention group had superior implementation of local high BMI guidelines, including; nutritional /weight gain advice (86% vs. 46%, p < 0.001), regular weighing (80% vs. 33%, p < 0.001), lactation consultant referrals (8% vs. 1%, p = 0.02), third trimester anaesthetic review and ultrasound (50% vs. 20.9%, p = 0.04 and 55% vs. 43%). Initiation of breastfeeding was higher in the intervention group (100% vs. 90%, p = 0.001). No significant difference was noted in Caesarean rate (30% vs 32%) and birthweight (3538 g vs 3560 g). Conclusions Women with high BMI enrolled in a specialised antenatal management programme received increased care, and had superior breastfeeding initiation rates. However, engagement was poor, and no significant differences were noted in antenatal or postnatal complications, mode of birth or neonatal outcome.


Author(s):  
Engin Yurtcu ◽  
Sibel Mutlu ◽  
Enis Ozkaya

OBJECTIVE: To investigate the effects of pre-pregnancy body mass index and weight gain during pregnancy on perinatal outcomes and delivery mode. STUDY DESIGN: In this retrospective cohort study, 722 pregnant women giving birth between 2018-2019 were screened from our hospital database. First, they were divided into four groups according to their pre-pregnancy body mass index (low-weight/normal-weight/overweight/obese), and then they were redivided into three groups according to pregnancy weight gain (≤7/8-15/≥16 kg). Prenatal body mass index and pregnancy weight gain were compared concerning maternal-neonatal results and mode of delivery. RESULTS: According to pre-pregnancy body mass index, among the obese pregnant group, gestational diabetes mellitus (p<0.001), preeclampsia (p=0.029), preterm delivery (p=0.011) and cesarean delivery (p=0.061) rates were more common. As the body mass index increases, neonatal intensive care requirement (p=0.0020) and low 1st minute APGAR scores (p=0.019) were detected more frequently. However, as pregnancy weight gain decreased, preterm delivery (p=0.041) increased. Also, birth weight increased (p<0.001) with the weight gain of the pregnant. Pregnant women gaining more than 16 kg were associated either with a lower <2500 g or a higher birth weight risk >4000 g. CONCLUSION: Pre-pregnancy high body mass index is associated with negative obstetric outcomes like gestational diabetes, preeclampsia, preterm delivery, and increased cesarean rates, and poor fetal incidences with a low APGAR score and high neonatal intensive care admission rates.


2021 ◽  
Vol 2 (1) ◽  
pp. 43-47
Author(s):  
Javier Sánchez-Romero

The global epidemic of obesity also affects pregnant women. External cephalic version is a procedure for achieving a cephalic presentation. Obesity has been associated with lower rates of ECV success. The main objective of this article is to analyze the trends in BMI in pregnant women who underwent ECV. A descriptive retrospective analysis of ECV performed in Hospital Clinico Universitario Virgen de la Arrixaca in Murcia (Spain) between 1st of January of 2014 and 31st of December 2018 has been carried out. 417 patients were recruited. The mean maternal BMI was 25.5 kg/m2 at 36 week’s gestation. If BMI is categorized, 2.6% (N=11) of the patients had a BMI below 18.5 kg/m2, 51.1% (N=213) had a BMI between 18.5-24.9 kg/m2, 30.9% (N=129) of the patients had a BMI between 25-29.9 kg/m2 and 14.0% (N=64) had a BMI above 30 kg/ m2. Mean maternal BMI had statistically significant changes between 2014 and 2018 (p<0.001). Maternal BMI has increased over the years in patients who undergo ECV. In patients who undergo ECV, maternal BMI should be related to socio-economic inequalities and social behavior in future researches. It should be also associated with maternal BMI of pregnant women who undergo ECV with ECV success rate and with the type of delivery of those pregnancies. Keywords: External Cephalic Version; Body Mass Index; Pregnant; Obstetrics; Obesity; Overweight. Abbreviations ECV: External Cephalic Version; BMI: Body Mass Index.


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