scholarly journals Synchronous papillary endometrial and ovarian cancer in a 64-year-old woman

2021 ◽  
Vol 11 (1) ◽  
pp. 252
Author(s):  
Ganesh B. Bharaswadkar ◽  
Nalan Babacan
Keyword(s):  
Ovarian Cancer ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Ovarian Tumors ◽  
Fallopian Tubes ◽  
Metachronous Cancer ◽  
Morphological Unit ◽  
Younger Age ◽  
Synchronous Malignancies ◽  
Female Genital

Obesity, nulliparity, and comparatively younger age may attribute a “hormonal field effect” which leads to the development of synchronous endometrioid cancers. The morphological unit consisting of the uterus, fallopian tubes, and ovary as part of the Mullerian system may explain the synchronous appearance of these malignancies. Synchronous endometrial and ovarian cancer (SEOC) is defined as the simultaneous presence of these dual cancers at the time of diagnosis as opposed to metachronous cancer where these two cancers are diagnosed at different chronologic time points. Synchronous malignancies in the female genital tract are very rare entities. Synchronous endometrial and ovarian tumors must be differentiated from either primary endometrium or ovarian tumors with metastasis. The landmark criteria for diagnosing such cases have been laid down by Ulbright and Roth.

scholarly journals Molecular Biology of Ovarian Cancer: From Mechanisms of Intraperitoneal Metastasis to Therapeutic Opportunities

Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1661
Author(s):  
Krzysztof Książek
Keyword(s):  
Ovarian Cancer ◽  
Molecular Biology ◽  
Cause Of Death ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Gynecological Tumors ◽  
Female Genital

Ovarian cancer (OC) is one of the most frequent malignancies of the female genital tract, and is still the leading cause of death from gynecological tumors [...]

scholarly journals Spectrum of histopathological lesions in the fallopian tubes

2013 ◽  
Vol 3 (5) ◽  
pp. 356-360 ◽  
Author(s):  
S Gon ◽  
A Basu ◽  
B Majumdar ◽  
TK Das ◽  
M Sengupta ◽  
...  
Keyword(s):  
Genital Tract ◽  
Histopathological Examination ◽  
Female Genital Tract ◽  
Secondary Malignancies ◽  
Fallopian Tubes ◽  
Serial Sections ◽  
Pathology Laboratory ◽  
Surgical Specimen ◽  
Neoplastic Lesions ◽  
Female Genital

Background: Fallopian tubes are common surgical specimen in the pathology laboratory; still there is a lack of data to describe the frequency of various histological fi ndings. The aim and objectives of this study was to describe the various histopathological fi ndings of fallopian tubes. Materials and Methods: Two thousand fi ve hundred and seventy fi ve cases where fallopian tubes were removed either separately or along with other female genital tract organs were studied retrospectively and their histopathological fi ndings documented. Results: Ectopic pregnancy comprised maximum number of cases closely followed by salpingitis. Primary neoplastic lesions were rare as compared to secondary malignancies. Serial sections of fallopian tube and sections from representative areas are essential for a pathologist so that the diagnosis of these pathological entities is not missed. Conclusion: Though the fallopian tubes remain unremarkable in majority of the surgical pathological specimens, it must be subjected for histopathological examination to demonstrate the pathological lesions. Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 356-360 DOI: http://dx.doi.org/10.3126/jpn.v3i5.7858

scholarly journals Synchronous primary tumors of the endometrium and ovary

1970 ◽  
Vol 2 (3) ◽  
pp. 189-192 ◽  
Author(s):  
S Karki ◽  
U Chapagain
Keyword(s):  
Genital Tract ◽  
Endometrial Hyperplasia ◽  
Female Genital Tract ◽  
Premenopausal Women ◽  
Ovarian Tumors ◽  
University Teaching ◽  
Primary Tumors ◽  
Atypical Endometrial Hyperplasia ◽  
Ovarian Cancers ◽  
Female Genital

Background: Primary synchronous cancer of the female genital tract is a relatively uncommon. Simultaneously detected endometrial and ovarian malignancies constitute the commonest occurrence. A set of pathological criteria has been described to differentiate synchronous primaries from metastatic tumors. The purpose of this study was to characterize patients with synchronous primary endometrial and ovarian tumors. Materials and Methods: This was a retrospective study done in Department of Pathology, Tribhuwan University Teaching Hospital from September 2006 to August 2011. The datas were retrieved from computer database. Results: There were totally of 10 cases of simultaneously detected endometrial and ovarian cancers. Out of 10 cases, 7 cases were synchronous primary endometrial and ovarian cancers while three were metastatic. Median age at presentation was 47.4 years. Six (85.8%) of these patients presenting with dual primary tumors were premenopausal. Grade 1 histology was seen in 57% of endometrial and 42% of ovarian tumors. Atypical endometrial hyperplasia was found in 42.8% of cases while none of the cases showed endometriosis. Conclusion: Though limited by relatively small number of cases, younger and premenopausal women were predisposed to developing synchronous primary tumors of the endometrium and ovary. DOI: http://dx.doi.org/10.3126/jpn.v2i3.6019 JPN 2012; 2(3): 189-192

scholarly journals Malignant Tumors of the Female Genital Tract – a Hospital Based Analysis

2016 ◽  
Vol 10 (2) ◽  
pp. 24-28
Author(s):  
R Joshi ◽  
G Baral ◽  
K Malla
Keyword(s):  
Ovarian Cancer ◽  
Cervical Cancer ◽  
Endometrial Cancer ◽  
Genital Tract ◽  
Malignant Tumors ◽  
Female Genital Tract ◽  
Limited Data ◽  
Corpus Uteri ◽  
Female Genital

Aims: The incidence of cancer and the cancer related deaths are increasing worldwide. There is limited data regarding  gynecological cancers in Nepal. This study is conducted to analyze the trends of female genital tract malignancies in Paropakar Maternity and Women’s Hospital (PMWH) and compare it with the national/international data.Methods: This was a retrospective study conducted in Department of Obstetrics/Gynecology and Pathology in PMWH.  All female diagnosed with the genital tract malignancies from July 2013 to July 2015 were included in the study.Results: Among 62 cases, cervical cancer was the commonest (71%) followed by ovarian cancer (14%), endometrial cancer (8%) and choriocarcinoma (3%). Majority of women belonged to 50-59 years for each type of tumors. Four-fifth of endometrial, half of the cervical and one-third of ovarian cancers were among grand-multipara. Sixty nine percent of women received treatment with 22 (9 cervical, 9 ovarian, 3 endometrial and one of corpus uteri)  surgical and 21 primary chemo/radiotherapy but 19 (31%) were lost for follow-up. Squamous type of cervical cancer was the commonest (93%).Conclusions: Cervical cancer was the commonest genital tract malignancy followed by ovarian cancer, endometrial cancer and choriocarcinoma. For each type of tumors, 50-59 years was the common age group and grand multiparity was seen in half of the women with the cervical cancer. Squamous type of cervical cancer was the commonest variety.  

scholarly journals Immune Pathogenesis of Asymptomatic Chlamydia trachomatis Infections in the Female Genital Tract

1995 ◽  
Vol 3 (4) ◽  
pp. 169-174 ◽  
Author(s):  
Steven S. Witkin
Keyword(s):  
Chlamydia Trachomatis ◽  
Genital Tract ◽  
Pregnancy Loss ◽  
Early Stage ◽  
Female Genital Tract ◽  
In Vivo Studies ◽  
Fallopian Tubes ◽  
Female Genital

Chlamydia trachomatis (CT) infections of the female genital tract, although frequently asymptomatic, are a major cause of fallopian-tube occlusion and infertility. Early stage pregnancy loss may also be due to an unsuspected and undetected CT infection. In vitro and in vivo studies have demonstrated that this organism can persist in the female genital tract in a form undetectable by culture. The mechanism of tubal damage as well as the rejection of an embryo may involve an initial immune sensitization to the CT 60 kD heat shock protein (HSP), followed by a reactivation of HSP-sensitized lymphocytes in response to the human HSP and the subsequent release of inflammatory cytokines. The periodic induction of human HSP expression by various microorganisms or by noninfectious mechanisms in the fallopian tubes of women sensitized to the CT HSP may eventually result in tubal scarring and occlusion. Similarly, an immune response to human HSP expression during the early stages of pregnancy may interfere with the immune regulatory mechanisms required for the maintenance of a semiallogeneic embryo.

scholarly journals Congenital absence of a part of the fallopian tube: a case report

2016 ◽  
Vol 6 (1) ◽  
pp. 320
Author(s):  
Mukta Agarwal ◽  
Hemali H. Sinha ◽  
. Anamika
Keyword(s):  
Case Report ◽  
Fallopian Tube ◽  
Genital Tract ◽  
Rare Case ◽  
Case Reports ◽  
Female Genital Tract ◽  
Fallopian Tubes ◽  
Rare Occurrence ◽  
Rare Case Report ◽  
Female Genital

Congenital malformations of female genital tract are frequently seen in Gynaecological clinics, incidence being upto 5-6% in cases of infertility. Most of these anomalies are related to uterus and vagina, abnormalities related to ovaries and fallopian tubes are of rare occurrence and the exact incidence of these anomalies are not known, only a few incidental case reports are available in literature. Here, we present a rare case report of absent mid- tubal segment of fallopian tube in a patient of infertility.

scholarly journals An Over-View of Tuberculosis of Female Genital Tract With Reference To Experience in a Medical College in Rural Set-Up in West Bengal: A Retrospective Two Year Study

2012 ◽  
Vol 11 (3) ◽  
pp. 185-190
Author(s):  
J Datta ◽  
TK Ghosh ◽  
S Ghosh ◽  
D Guha
Keyword(s):  
Genital Tract ◽  
Medical Science ◽  
Female Genital Tract ◽  
Cystic Teratoma ◽  
Clinical Findings ◽  
Fallopian Tubes ◽  
Medical College ◽  
Benign Cystic Teratoma ◽  
Set Up ◽  
Female Genital

Aim: To determine frequency of female genital tract (FGT) tuberculosis (TB) in the gynecological biopsies received in the Department of pathology of a peripheral medical college. Methods: This is a retrospective study conducted in the Department of Pathology of Burdwan Medical College & Hospital. Histopathological records of two year (2008-2010) were retrieved and searched for the cases of female genital tract TB. Relevant histopathological findings and clinical data were recorded and analyzed. Results: There were 1537 cases of gynecological biopsy and 9 cases were diagnosed as FGT tuberculosis based on histopathological and clinical findings. Ovarian benign cystic teratoma was seen in one case along with ipsilateral tuberculous salpingitis, one case showed B/L ovarian tuberculosis with involvement of both the tubes. Bilateral fallopian tubes were involved in 2 cases and endometrial tuberculosis was diagnosed in 5 cases with 1 case showing simultaneous involvement of the cervix. In one case omental biopsy received along with tubal specimen showed tuberculous granulomas. Conclusion: FGT tuberculosis was usually seen in  age 16-28 years and constituted 0.59% of total gynecological cases. Fallopian tubes, ovaries and endometrium and cervix were affected with the involvement of peritoneum or omentum, commonest being tuberculous endometritis. Histopathology, in association with clinical findings still remains gold standard for the diagnosis of FGT tuberculosis in our country despite advancement in diagnostic modalities; however, incidental histological detection in clinically unanticipated cases is not an uncommon event. DOI: http://dx.doi.org/10.3329/bjms.v11i3.11719 Bangladesh Journal of Medical Science Vol. 11 No. 03 July’12  

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