Histopathological study of nasal lesions: 2 years study

ackground: Majority of the nasal lesions are polypoid. It is difficult to comment upon the nature of the nasal lesion- whether neoplastic or non-neoplastic. Hence histopathological examination is essential for both ENT surgeons as well as pathologists. Aim to study the incidence of different nasal lesion. Also, to find out frequency of inflammatory, benign and malignant conditions of nasal lesions and to compare various histopathological lesions of nasal mass in relation to age, sex and site distribution.Methods: The present study was undertaken in histopathology laboratory of Department of Pathology, P.D.U. medical college and hospital, Rajkot for period of 2 years from October 2013 to September 2015. A histopathological study of total 100 cases of nasal lesions was done. Tissue were processed and studied.Results: Out of 100 cases, 59 were males and 41 were females. Male to Female ratio was 1.44:1. Maximum numbers of nasal lesions were detected in age group of 11-20 years with 24 (24.00%) cases. Out of these 100 cases, 80 (80.00%) were non neoplastic and 20 (20.00%) were of neoplastic origin. In neoplastic lesions, 12(12.00%) were benign, 1 (1.00%) was borderline and 7 (7.00%) were malignant nasal lesions. Non neoplastic lesions were composed of the majority of cases followed by benign neoplastic lesions.Conclusions: Most of malignant neoplastic lesions were occurs after 40 years of age. Incidence of malignant neoplastic lesions was increase with advanced age.

Download Full-text

Clinicopathological study of sinonasal masses

Bangladesh Journal of Otorhinolaryngology ◽

10.3329/bjo.v16i1.5776 ◽

1970 ◽

Vol 16 (1) ◽

pp. 15-22 ◽

Cited By ~ 5

Author(s):

Abu HenaMohammad Parvez Humayun ◽

AHM Zahurul Huq ◽

SM Tarequddin Ahmed ◽

Md Shah Kamal ◽

Kyaw Khin U ◽

...

Keyword(s):

Histopathological Examination ◽

Malignant Lesion ◽

Malignant Tumour ◽

Neck Surgery ◽

Female Ratio ◽

Medical College ◽

Male To Female ◽

Study Setting ◽

Head Neck Surgery ◽

Head Neck

Objective: To observe the incidence, clinical presentation and to perform comparative studyof different sinonasal masses. Study design: Prospective study. Setting: Department ofotolaryngology and Head-Neck Surgery & ENT OPD of Chittagong Medical College Hospital.Patients & methods: 50 patients are included in this study (39 male & 11 female) between theages of 3 years and 80 years who were treated between August 2006 to January 2007. Studybased on history, clinical, radiological, laboratory and histopathological examination. Results:Mean age for male was 35.12 years and for female was 22.63 years. Male to female ratio was3.5:1. Highest frequency was noted in second decade. Most of patient (78%) were from poorclass. Frequency of inflammatory nasal masses were more in second decade, benign tumourin fourth and fifth decade, malignant tumour in second decade (OAN & NHL) and fifth andsecond decades (others). Rhinosporidiosis were most frequent inflammatory nasal masses.Nasal obstruction was the commonest and orbitus symptoms were less frequent symptoms.But orbital symptoms were more prevalent in malignant lesion. Conclusion: sinonasal massesare found in all age group. Rhinosporidiosis are appearing to be the commonest nasal masses.The prevalence of nasal polyp is also high. Among the malignant sinonasal masses thepercentage of squamous cell carcinoma is high.DOI: 10.3329/bjo.v16i1.5776Bangladesh J Otorhinolaryngol 2010; 16(1): 15-22

Download Full-text

DEMOGRAPHIC STUDY OF DEATHS DUE TO ROAD TRAFFIC ACCIDENTS, EXAMINED IN DR. S.N. MEDICAL COLLEGE, JODHPUR (RAJ.)

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i8.1364 ◽

2020 ◽

Vol 4 (8) ◽

Author(s):

Kana Ram Patel ◽

Jagdish Jugtawat ◽

Shalender Kumar ◽

P.C. Vyas

Keyword(s):

Head Injury ◽

Traffic Accidents ◽

Road Traffic ◽

Head Injuries ◽

Subdural Hemorrhage ◽

Age Group ◽

Road Traffic Accidents ◽

Female Ratio ◽

Medical College ◽

Male To Female

Accidents are not due to external factors all the time but often they occur due to failure of control of self-conscience and free thoughts. Road Traffic Accidents is still the major cause of death worldwide including India. A retrospective study has been conducted in Dr. S.N. Medical College, Jodhpur (Raj.), in the year 2019 to study the pattern and distribution of Head Injuries of fatal road traffic accidents and to prepare the demographic profile of it. Out of total 901 cases, male to female ratio was 9:1, and commonest age group affected was 21-30 years (39.8%). Among total victims, Hindus were 748 (83%) and rests were Muslims 103 (11.4%) and other religions. Head injury was the most common injury, present alone in 509 cases (56.4%) and in 392 (43.6) cases along with other injuries. Skull fractures were found in 451 (50.5), in which linear/fissure fracture (32.9%) was most common. Most common bone fractured was temporal bone. The commonest variety of intracranial hemorrhage was subdural hemorrhage and craniotomy was done in 29 (3.2%) cases. Keywords: Accidents, Road traffic, Head injury, Fractures.

Download Full-text

A study on clinical characteristics of herpes zoster in a tertiary care center

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20170081 ◽

2017 ◽

Vol 3 (1) ◽

pp. 79

Author(s):

Rachana R. ◽

Shivaswamy K. N. ◽

Anuradha H. V.

Keyword(s):

Herpes Zoster ◽

Clinical Characteristics ◽

Care Center ◽

Tertiary Care ◽

Age Groups ◽

Age Group ◽

Female Ratio ◽

Varicella Zoster ◽

Medical College ◽

Male To Female

Background: Herpes zoster (HZ), also known as shingles, derived from the Latin word Cingulum, for “girdle”. This is because a common presentation of HZ involves a unilateral rash that can wrap around the waist or torso like a girdle. HZ results due to reactivation of an earlier latent infection with the varicella zoster virus (VZV) in dorsal root ganglia. It occurs at all age groups, common over 60 years of age. It is estimated that in non-immune populations, approximately 15 cases per 1000 people occur per year. The objective of the study was to study the clinical characteristics in patients with uncomplicated herpes zoster.Methods: A total of 72 patients attending dermatology OPD at Ramaiah medical college between June 2013 to September 2014 were recruited after obtaining informed consent. A detailed history regarding onset of rash, pain, progression, duration and distribution of the lesions were recorded. Demographic information including age, sex, and any other co morbidities noted. Tzanck smear and serology for HIV was done where-ever necessary.Results: Of the 72 patients, females outnumbered males [M=35(48.61%), F=37 (51.39%)] with male to female ratio of 0.9 to 1. The mean age of presentation was 58±18 years. Majority of the patients (54%) were in the age group of 51 to 70 years followed by 31-50 years (25%). Least number of cases (9%) was in the age group of 21 to 30 years. Of the 72 subjects, thoracic involvement was noted in 30.6%, followed by lumbar (22%), and trigeminal (16%). Cervical (4%) and sacral (2%) involvement was the least. Conclusions: Herpes zoster commonly occurs in old age and the presenting symptom being pain and burning sensation. Thoracic dermatome is the commonest site. Immunocompromised states like diabetes, malignancy and HIV can increase the risk of developing herpes zoster.

Download Full-text

CLINICOPATHOLOGICAL STUDY OF GASTRIC BIOPSIES

10.36106/ijsr/8534692 ◽

2021 ◽

pp. 38-40

Author(s):

Manu Jethalya ◽

Saurabh Totla

Keyword(s):

Clinical Presentation ◽

Early Stage ◽

Gastric Biopsy ◽

Histopathological Study ◽

Age Group ◽

Malignant Tumours ◽

Early Management ◽

Medical College ◽

Neoplastic Lesions ◽

Gastric Biopsies

Background: Stomach is an important site for variety of lesions especially malignant tumours. Gastric biopsies along with clinical prole of cases play an important role in the diagnosis of gastric neoplasm and therefore aids in early management. Aim and Objectives: To study the histopathology of Gastric biopsies and correlate them with clinical presentation, age, sex and to differentiate them between neoplastic and non neoplastic lesions. Materials and Methods: The prospective study was done in the Department of Pathology Geetanjali Medical College and Hospital, Udaipur between 1stJanuary 2019 to 30thJune 2020. A total of 83 gastric biopsies were included in the study and were analyzed along with their clinical proles. Results: A total of 83 gastric biopsies were included in the study. Most commonly affected age group was 50-69 years with 41 patients (49.40%) followed by 40-49 years with 14(16.87%). Out of 83 cases, 58 (69.88%) were males & 25 (30.12%) were females, 26 (31.33%) cases were non neoplastic & 57 (68.67%) cases were neoplastic.Conclusion: The gastric biopsy not only permits exact diagnosis of specic entity but also helps to plan for early medical or surgical therapy. The histopathological study detects mucosal lesions at an early stage especially atrophy, metaplasia and dysplasia as to prevent progress of these lesions to invasive cancer.

Download Full-text

A COMPARATIVE STUDY OF TYMPANOPLASTY WITH OR WITHOUT MASTOIDECTOMY IN TUBOTYMPANIC TYPE OF CHRONIC SUPPURATIVE OTITIS MEDIA

10.36106/ijsr/7822895 ◽

2021 ◽

pp. 71-73

Author(s):

Mrinalini Raman ◽

Khushbu Rani ◽

Kameshwar Prasad Singh ◽

Debarshi Jana

Keyword(s):

Developing Countries ◽

Otitis Media ◽

Age Group ◽

Hearing Improvement ◽

Suppurative Otitis Media ◽

Female Ratio ◽

X Ray ◽

Medical College ◽

Cortical Mastoidectomy ◽

Male To Female

Background: CSOM is one of the most common ear diseases in developing countries. Lack of an aerating mastoidectomy at the time of the initial tympanoplasty may be a signicant source of failure in patients with chronic non-cholesteatomatous otitis media so cortical mastoidectomy along with tympanoplasty has for long been considered the surgical procedure of choice. The purpose of our study is to ascertain the effectiveness of tympanoplasty with or without cortical mastoidectomy. Methods: Our study was carried out in the Department of Otorhinolaryngology, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar. It included 50 patients of CSOM tubotympanic type of age between 15 years to 45 years and of either sex who were diagnosed and treated in E.N.T Department during the study period February 2019 to January 2020. Out of 50 patients who underwent surgery in 25 cases tympanoplasty with mastoidectomy was done and tympanoplasty without mastoidectomy was performed in 25 cases. Results: Commonest age group was 15-19 years. Male to female ratio was 1.6:1. In x-ray bilateral mastoids Schuller's view, 24 patients (48%) had sclerotic mastoids and 26 patients (52%) showed pneumatic mastoids. Clinical improvement, graft uptake and postoperative hearing improvement was similar in both the groups. Conclusions: Most common age group of presentation with CSOM tubotympanic type is 15-25 years. CSOM tubotympanic type appears to be more common in males. Hearing improvement following tympanoplasty alone and tympanoplasty with mastoidectomy were comparable in both the groups. Mastoidectomy with tympanoplasty does not give additional benet in terms of hearing improvement.

Download Full-text

Histopathological Study of Skin Adnexal Tumours—Institutional Study in South India

Journal of Skin Cancer ◽

10.1155/2014/543756 ◽

2014 ◽

Vol 2014 ◽

pp. 1-4 ◽

Cited By ~ 2

Author(s):

Ankit Sharma ◽

Deepak G. Paricharak ◽

Jitendra Singh Nigam ◽

Shivani Rewri ◽

Priyanka Bhatia Soni ◽

...

Keyword(s):

Malignant Tumors ◽

Neck Region ◽

Body Part ◽

Sebaceous Carcinoma ◽

Benign Tumors ◽

Histopathological Study ◽

Age Group ◽

Female Ratio ◽

Medical College ◽

Adnexal Tumors

Objective. The aim of this study was correlation of skin adnexal tumors with age, sex, and location and determining its incidence in the Department of Pathology at Dr. D. Y. Patil Medical College and Hospital, Kolhapur, Maharashtra.Material and Methods. 56 cases were included in this study from Jan 2004 to June 2010 with respect to incidence of adnexal tumors, age, and sex distribution. All slides were stained with haematoxylin and eosin and then findings were corroborated with special stains like PAS and reticulin wherever required.Results. 80.36% (45/56) were benign and 19.64% (11/56) were malignant adnexal tumors. The sweat gland tumors constituted the largest group (42.86% 24/56) cases followed by the hair follicle tumors (35.71%, 20/56) of cases and sebaceous gland tumors (21.43%, 12/56) cases. Overall male : female ratio was 1.07 : 1. The commonest age group was 51–60 years and the commonest affected body part was head and neck region (64.28%, 36/56) followed by trunk (14.28%, 8/56). Clear cell hidradenoma and pilomatricoma were commonest benign tumors and sebaceous carcinoma was the only malignant tumor seen.Conclusion. The incidence of benign skin adnexal tumors was more as compared to the malignant tumors. Malignant tumors were seen in older age group, usually over 50 years of age.

Download Full-text

A study of association of H. pylori infection and cholelithiasis

International Surgery Journal ◽

10.18203/2349-2902.isj20180377 ◽

2018 ◽

Vol 5 (2) ◽

pp. 701

Author(s):

Virendra S. Athavale ◽

Shivmurti N. Khandalkar ◽

Prachi C. Bhide ◽

Iresh Shetty ◽

Aditya Lad

Keyword(s):

Positive Association ◽

Age Group ◽

Cross Sectional ◽

Female Ratio ◽

Male Predominance ◽

Medical College ◽

The Mean ◽

H Pylori ◽

Male To Female

Background: Aims and objective of the study was to study the association of H. Pylori infection and cholelithiasis.Methods: The study was conducted at Dr. D. Y. Patil Medical College and Hospital, DPU University, for a period of 2 years and is a descriptive cross-sectional type of study using 100 patients.Results: In this study 26 % of total patients were seen in the age group of 21-30 years. The mean age of the patients was 26 years. 78 patients in present study were male (78%) and only 22 were females (22%) male predominance was seen. male to female ratio is 3.5:1. 18 % patients show association with cholelithiasis and 84 patients were detected positive by RUT method.Conclusions: H. pylori infection has a positive association with cholelithiasis and if eradicated, may lead to prevention of gallstones.

Download Full-text

Clinical, histopathological and immunofluorescent study of vesicobullous lesions of skin

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20191341 ◽

2019 ◽

Vol 7 (4) ◽

pp. 1288

Author(s):

Seeram Satish Kumar ◽

Bhagyalakshmi Atla ◽

Guru Prasad Patnala ◽

Kukkala Saraswati Sarat Srinivas ◽

Saraswathi Samantra ◽

...

Keyword(s):

Bullous Pemphigoid ◽

Histopathological Examination ◽

Pemphigus Vulgaris ◽

Direct Immunofluorescence ◽

Pemphigus Foliaceus ◽

Female Ratio ◽

Medical College ◽

Intensive Investigation ◽

Male To Female

Background: Vesiculobullous diseases have been the focus of intensive investigation in recent years. However, these disorders are still associated with substantial morbidity, considerable mortality and impaired quality of life. Accurate diagnosis of vesiculobullous lesions of skin entails evaluation of clinical, histopathologic and immunofluorescence findings.Methods: Hospital based prospective study for a period of 24 months from August 2014 to July 2016 in the Department of Pathology at Andhra Medical College, Visakhapatnam, India. Total of 50 patients aged 3-70 years with vesiculobullous lesions of both sexes attending the Department of Dermatology were selected and analysed clinically, histopathological examination and direct immunofluorescence (DIF).Results: In the present study, majority of patients presented between 51-60 yrs of age (32%) with male to female ratio of 1.08:1 and mean age of 46.02 years. Pemphigus vulgaris constituted the most common vesiculobullous disorder (32%) followed by bullous pemphigoid and pemphigus foliaceous, 18% each. Bullae were located intra epidermally in 68% and sub epidermally in 32% of the patients. DIF was positive in 80% of the cases. Overall clinicopathological correlation was established in 74%. Overall histopathological and direct immunofluorescence correlation was established in 78%. Out of 50 cases, 35 cases (70%) correlated clinically and histo-pathologically with direct immunofluorescence.Conclusions: In the present study, on histopathological examination alone pemphigus foliaceus and pemphigus vulgaris could be differentiated. Direct immunofluorescence was useful in differentiating epidermolysis bullosa acquisita from bullous pemphigoid which have similar histopathological picture. This study proves that direct immunofluorescence is confirmatory as well as diagnostic for vesiculobullous disorders.

Download Full-text

FNAC as a Diagnostic Tool in the Evaluation of Cytomorphological Spectrum of Peripheral Lymphadenopathy along with Histopathological Agreement - An Experience in a Tertiary Teaching Hospital of Northern India

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2020/601 ◽

2020 ◽

Vol 7 (49) ◽

pp. 2937-2942

Author(s):

Sima Chauhan ◽

Simanta Kumar Behera

Keyword(s):

Diagnostic Tool ◽

Histopathological Examination ◽

Age Groups ◽

Histopathological Diagnosis ◽

Anatomical Site ◽

Safe Procedure ◽

Age Group ◽

Female Ratio ◽

Tertiary Teaching ◽

Neoplastic Lesions

BACKGROUND Lymphadenopathy is one of the commonest presentations in clinical practice. Fine Needle Aspiration Cytology (FNAC) is an established, easy, cost effective, diagnostic tool for lymphadenopathies. Judicious application of FNAC can avoid the need of biopsy. We wanted to compare the accuracy of FNAC and histological analysis of peripheral lymphadenopathy among patients visiting the Departments of Oncology, Pathology, Surgery of K.D. Medical College and determine the most prevalent cause of peripheral lymphadenopathy among different age groups of patients. METHODS This study was done among cases of peripheral lymphadenopathy whose FNAC & biopsy were available. 112 cases of lymph node FNACs were carried out in the Dept. of Pathology for a period of one and half years from July 2018 till December 2019. Special stains were used whenever necessary. RESULTS Out of 112 cases studied 68 cases were male and 44 cases were female. Ratio of M : F = 1.5. The commonest anatomical site for lymphadenopathy was cervical (70 %) followed by supraclavicular (13 %) and axillary (10 %). Coming to the spectrum of the disease 103 cases (91.9 %) were non neoplastic lesions and 9 cases 8.03 % were neoplastic lesions. Reactive hyperplastic was the most common condition 51 cases (45.5 %) followed by tuberculosis 34 cases (30.35 %). Out of cases 9 cases (8.03 %) of malignancy, 5 cases (4.4 %) were metastatic deposits & 4 cases (3.57 %) were lymphomas. The peak age group ranged between 21 - 30 years. Cervical location of distribution of lymphadenopathy is noticed to be highest (70 %), which is then followed by, supra clavicular (13 %), axillary (10 %) and inguinal (5 %). (Maximum number of cases were found in the age group of 21 yr. - 30 yr., least number of cases seen in the age group of 61 yr. – 70 yr. Correlative study between cytopathological &and histopathological examination of lymphadenopathy showed diagnostic discordance in three cases and concordance in 109 cases. CONCLUSIONS Apart from reactive hyperplasia, tuberculosis is the commonest cause of lymphadenopathy & males are commonly affected. FNAC is a safe procedure with high degree of sensitivity and specificity and concordance of 96.64 % with histopathological diagnosis. For confirming the diagnosis of lymph nodes, histopathology is the gold standard. KEYWORDS Lymphadenopathy, FNAC, Histopathology, Biopsy, Tuberculosis

Download Full-text

A comparative study of tympanoplasty with or without mastoidectomy in tubotympanic type of chronic suppurative otitis media

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20190029 ◽

2019 ◽

Vol 5 (2) ◽

pp. 314 ◽

Cited By ~ 1

Author(s):

Rachna Vijayan Nambiar ◽

G. Priyadarshini ◽

Aishwarya Tiwari

Keyword(s):

Otitis Media ◽

Additional Benefit ◽

Age Group ◽

Hearing Improvement ◽

Suppurative Otitis Media ◽

Female Ratio ◽

X Ray ◽

Medical College ◽

Cortical Mastoidectomy ◽

Male To Female

Background: CSOM is one of the most common ear diseases in developing countries. Lack of an aerating mastoidectomy at the time of the initial tympanoplasty may be a significant source of failure in patients with chronic non-cholesteatomatous otitis media so cortical mastoidectomy along with tympanoplasty has for long been considered the surgical procedure of choice. The purpose of our study is to ascertain the effectiveness of tympanoplasty with or without cortical mastoidectomy.Methods: Our study was carried out in the Department of Otorhinolaryngology, Aarupadai Veedu Medical College, Pondicherry. It included 50 patients of CSOM tubotympanic type of age between 15 years to 45 years and of either sex who were diagnosed and treated in E.N.T Department during the study period October 2016 to August 2018. Out of 50 patients who underwent surgery in 25 cases tympanoplasty with mastoidectomy was done and tympanoplasty without mastoidectomy was performed in 25 cases. Results: Commonest age group was 15-19 years. Male to female ratio was 1.6:1. In x-ray bilateral mastoids Schuller’s view, 24 patients (48%) had sclerotic mastoids and 26 patients (52%) showed pneumatic mastoids. Clinical improvement, graft uptake and postoperative hearing improvement was similar in both the groups.Conclusions: Most common age group of presentation with CSOM tubotympanic type is 15-25 years. CSOM tubotympanic type appears to be more common in males. Hearing improvement following tympanoplasty alone and tympanoplasty with mastoidectomy were comparable in both the groups. Mastoidectomy with tympanoplasty does not give additional benefit in terms of hearing improvement.

Download Full-text