scholarly journals A study to assess prevalence of treatment default among lung cancer patients registered at a tertiary care hospital

Author(s):  
Lokendra Dave ◽  
Vikas Mishra ◽  
Rakesh C. Gupta ◽  
Neeraj Gour ◽  
Nishant Shrivastava ◽  
...  

Background: Lung cancer is among the five main types of cancer leading to overall cancer mortality contributing about 1.3 million deaths/year globally. Completion of treatment among lung cancer patients is one of key factor for the survival and longevity of patients. So, we have tried to find out prevalence of treatment default through this study.Methods: This is a cross-sectional descriptive study (including retrospective secondary and prospective primary data) using data base of patients of primary lung cancer diagnosed between 1st January 2006 to 31st December 2012 in indoor and outdoor of department of Respiratory Medicine, J.L.N. Medical College, Ajmer, a tertiary level hospital and teaching center.Results: Incidence of lung cancer is significantly higher among young female (10.23%) as compared to young male (8.74 %). Whereas in older group number of male suffering from lung cancer than female. Total 269 (20.7%) patients defaulted from planned treatment and most of them ultimately drop-out from chemotherapy cycles. Intercycle delay of 2 weeks-1m commonly seen.Conclusions: It provides future implication to researchers to explore reasons of these defaults and drop outs so that more evidences can be generated in this direction for the ultimate betterment of lung cancer patients.

Author(s):  
Jayita Pal ◽  
Avradip Santra

Background: Lung cancer is one of the commonest cancer worldwide and also in India. Being a chronic disease, it is expected to result in disability during the course of the illness. Disability in turn results in deterioration of mental health and leads to poor quality of life. The present study intended to assess the degree of disability among lung cancer patients and to find out the covariates of the same.Methods: An institution based cross-sectional study had been conducted over a period of six months among lung cancer patients attending a tertiary care centre. Exit interview had been conducted with a pretested schedule after taking informed consent. Disability had been assessed by WHO Disability Assessment Schedule 2.0 (WHODAS 2.0). Data were entered and analysed in SPSS 20.0 version.Results: A total of 210 patients were recruited in this study. Half of the study population were suffering from higher level of disability. Multivariate analysis revealed degree of disability was higher among the patients who were financially dependent to others, had advanced stage of the disease and when time since diagnosis was more than one month.Conclusions: Holistic approach needs to be taken up to address this alarming issue of disability and its consequences among lung cancer patients. The approach should include various rehabilitative measures, social security schemes by the government and active involvement of non-governmental organisations.


Author(s):  
Jayita Pal ◽  
Avradip Santra

Background: Lung cancer is the commonest cancer worldwide considering its incidence and mortality. It not only affects the life of the patient, but also has significant impact on the life of the primary caregivers too. The study aimed to assess the Quality of Life (QOL) among caregivers of lung cancer patients and to find out its determinants.Methods: It was an institution based cross-sectional study conducted in a tertiary care center of Kolkata with the help of a predesigned, pretested, structured, standardized questionnaire where 210 patient-caregiver dyads were included by complete enumeration method to assess quality of life of the caregivers and its possible predictors.Results: Half of the caregivers experienced poor quality of life (overall QOL score ≤ median score) as assessed by QOLLTI-F (Quality of Life in Life-Threatening Illness-Family Carer Version). Multivariate analyses suggested that gender, religion, area of residence, financial burden, stage and type of lung carcinoma, disability and depression among the patients were important determinants of quality of life of the caregivers.Conclusions: Comprehensive care covering different domains like financial risk protection, psycho-social assistance through governmental and also different non-governmental initiatives, self-help groups are the needs of the hour to address this important public health issue as caregiver’s life is equally important as that of the patient and they are highly interdependent.


2017 ◽  
Vol 06 (04) ◽  
pp. 171-175 ◽  
Author(s):  
Randeep Singh ◽  
Nitesh Rohtagi

Abstract Aims: The primary objective of this study was to estimate the clinicopathological and molecular profile of lung cancer patients along with the evaluation of their clinical characteristics at a tertiary care hospital in Northern India. Subjects and Methods: A total of 421 patients with lung cancer histology who were treated at Max Super Speciality Hospitals were included in the study. The study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki and permission was obtained from the Ethics Committee before the start of the study. Clinical characteristics and molecular profiling data were collected from the patient's medical records. Results: There were 330 (78.4%) men and 91 (21.6%) women with a median age of 62 years (range: 30–93 years). Of the 421 patients, 388 (92.2%) patients had the nonsmall cell lung cancer (NSCLC) histology whereas 33 (7.8%) patients were of SCLC histology. Histology and gender had a significant association with NSCLC and SCLC (P < 0.05). Epidermal growth factor receptor (EGFR) and echinoderm microtubule-associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene testing was done in 120 and 93 patients, respectively. Of the 120 patients, 24 (20%) cases were positive for EGFR mutations whereas EML4-ALK fusion gene was present in 8 (8.6%) out of 93 patients. Conclusions: Our study confirms the importance of molecular testing in the NSCLC patient subgroup with an aim to identify the exact molecular targets that can benefit from the newer generation of targeted therapies.


2017 ◽  
Vol 6 (60) ◽  
pp. 4403-4406
Author(s):  
Anand Kumar ◽  
Luvkush Luvkush ◽  
Sanjay Verma ◽  
Prashant Yadav ◽  
Avadhesh Kumar ◽  
...  

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