scholarly journals Spectrum and review of MRI findings in hypophysitis

2018 ◽  
Vol 6 (11) ◽  
pp. 3789
Author(s):  
Niharika Kadiyala ◽  
Arunan Murali ◽  
Venkata Sai
Keyword(s):  
Pituitary Gland ◽  
Mass Effect ◽  
Surgical Decompression ◽  
The Body ◽  
Posterior Pituitary ◽  
Imaging Studies ◽  
Radiological Findings ◽  
Mri Findings ◽  
Granulomatous Hypophysitis ◽  
Immunological Markers

Inflammation of the pituitary infundibulum and pituitary gland (hypophysis) is called hypophysitis. The causes may be primary (lymphocytic hypophysitis, granulomatous hypophysitis, xanthomatous hypophysitis, necrotizing hypophysitis) or secondary due to spread of disease from elsewhere in the body. Authors report three cases of primary hypophysitis with radiological findings ranging from simple thickening of the infundibulum, posterior pituitary (infundibuloneurohypophysitis), thickening of the entire gland and infundibulum (panhypophysitis) and mass forming lesion in the anterior pituitary gland (adenohypophysitis). Diagnosis is arrived based on combined findings of clinical features, endocrinological assessment, Immunological markers, imaging studies and histopathology (if necessary). Conservative, supportive treatment is usually the treatment of choice with surgical decompression reserved for cases with extensive mass effect. Authors conclude that hypophysitis should be considered as a differential diagnosis for lesions of the pituitary.

scholarly journals Granulomatous infective spondylitis in a patient presenting with progressive difficulty in walking: the differential between tuberculosis and brucellosis

2019 ◽  
Vol 12 (11) ◽  
pp. e232540
Author(s):  
Eleni Papachristodoulou ◽  
Loukas Kakoullis ◽  
Stylianos Louppides ◽  
George Panos
Keyword(s):  
Cerebrospinal Fluid ◽  
Spinal Canal ◽  
Granulomatous Inflammation ◽  
Mass Effect ◽  
Surgical Decompression ◽  
Lower Limbs ◽  
Imaging Studies ◽  
History Of ◽  
Infective Spondylitis ◽  
Infectious Spondylitis

We report a case of infectious spondylitis in a 52-year-old woman who presented with progressive difficulty in walking. The patient had a 2-month long history of neurological symptoms, which progressed rapidly to paraplegia, following her admission. Imaging studies demonstrated the presence of vertebral lesions as well as additional tissue with inflammatory elements in the spinal canal, which caused a mass effect. In combination with the presence of increased cells and protein in the cerebrospinal fluid (CSF), the differential was steered towards causes of infectious spondylitis, primarily tuberculosis. However, brucellosis was also considered, as it is endemic in our area. Prompt surgical decompression produced biopsy samples, which confirmed the presence of granulomatous inflammation. The patient was started on an empiric regimen covering both for tuberculosis and brucellosis, and gradually regained full mobility in her lower limbs. The differential of infectious spondylitis is discussed, with an emphasis on the differentiation between tuberculosis and brucellosis.

Melatonin Modulates Lactation by Regulating Prolactin Secretion Via Tuberoinfundibular Dopaminergic Neurons in the Hypothalamus- Pituitary System

2020 ◽  
Vol 21 (8) ◽  
pp. 744-750 ◽  
Author(s):  
Hongyang Li ◽  
JingyaWei ◽  
Fengtao Ma ◽  
Qiang Shan ◽  
Duo Gao ◽  
...  
Keyword(s):  
Pineal Gland ◽  
Pituitary Gland ◽  
Antioxidant Capacity ◽  
Dopaminergic Neurons ◽  
Growth And Development ◽  
Endocrine System ◽  
Mammary Glands ◽  
Prolactin Secretion ◽  
The Body ◽  
Stimulation Of

In-depth studies have identified many hormones important for controlling mammary growth and maintaining lactation. One of these is melatonin, which is synthesized and secreted by the pineal gland to regulate circadian rhythms, improve antioxidant capacity, and enhance immunity. Prolactin is secreted by the pituitary gland and is associated with the growth and development of mammary glands as well as initiation and maintenance of lactation. The hypothalamus-pituitary system, the most important endocrine system in the body, regulates prolactin secretion mainly through dopamine released from tuberoinfundibular dopaminergic neurons. This review provides a reference for further study and describes the regulation of lactation and prolactin secretion by melatonin, primarily via the protection and stimulation of tuberoinfundibular dopaminergic neurons.

Role of Panchakarma in the management of Hypothyroidism

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Dr.Suraj Kumbar ◽  
Dr.Lohith BA ◽  
Dr.Ashvinikumar M ◽  
Dr. Amritha R ◽  
Dr. Shameem Banu
Keyword(s):  
Metabolic Rate ◽  
Pituitary Gland ◽  
Life Style ◽  
The Body ◽  
Management Guidelines ◽  
Quality Of Food ◽  
Sedentary Life ◽  
Sedentary Life Style

We are in technical era where there is more of sedentary life style and stress along with this urbanization is affecting our quality of food and health. This is leading to many lifestyle disorders and hormonal imbalances in our body. Hypothyroidism one among the endocrinal disorder. Thyroid is an endocrinal gland secrets T3 and T4 hormones regulated by TSH which is secreted by Pituitary gland. These hormones have two major effects on the body, 1) To increase the overall metabolic rate in the body 2) To stimulate growth in children. Hypothyroidism is common health issue in India. The highest prevalence of hypothyroidism (13.1%) is noted in people aged 46-54yrs old. With people aged 18-35 yrs being less affected (7.5%). To prevent these hazards Panchakarma is beneficiary to maintain metabolic rate. Here an attempt is made to diagnose hypothyroidism in the light of Ayurveda and management guidelines through Panchakarma.

Disequilibrium in patients with atherosclerosis

Neurology ◽  
1998 ◽  
Vol 51 (2) ◽  
pp. 570-573 ◽  
Author(s):  
Vincent I.H. Kwa ◽  
Laura H. Zaal ◽  
Bernard Verbeeten ◽  
Jan Stam ◽  
Keyword(s):  
Sickness Impact Profile ◽  
Statistical Significance ◽  
Structured Interview ◽  
The Body ◽  
Pontine Nuclei ◽  
Mri Findings ◽  
Initial Manifestation ◽  
Walking Test ◽  
Walking Tests ◽  
Body Care

Objective: To examine the clinical relevance of isolated pontine hyperintense lesions(PHLs) on MRI in patients with atherosclerosis.Methods: Seventeen atherosclerotic patients with isolated PHL on MRI were compared with 17 patients without PHL and were matched for age, sex, and initial manifestation of atherosclerosis. Subjects and observer were blinded to the MRI findings. We assessed symptoms, impairment, and disability with a structured interview and neurologic examination as well as disability scales.Results: On all items, patients with PHL scored worse that did their controls. We found the largest differences in frequencies of symptoms of disequilibrium, difficulties with speech or swallowing, the Timed Walking Test, and the body care and movement subscale of the Sickness Impact Profile. Except for disequilibrium (p = 0.04), these differences did not reach statistical significance. Abnormal tandem-walking tests were more frequent in patients than they were in controls. Pyramidal signs were equally distributed.Conclusions: We propose PHL as a cause of symptoms of disequilibrium in patients with atherosclerosis. Symptoms are probably elicited by dysfunction of the corticopontine fibers, the pontocerebellar fibers, or the pontine nuclei.

The Medial Wall of the Cavernous Sinus: Microsurgical Anatomy

Neurosurgery ◽  
2004 ◽  
Vol 55 (1) ◽  
pp. 179-190 ◽  
Author(s):  
Alexandre Yasuda ◽  
Alvaro Campero ◽  
Carolina Martins ◽  
Albert L. Rhoton ◽  
Guilherme C. Ribas
Keyword(s):  
Pituitary Gland ◽  
Cavernous Sinus ◽  
Thin Sheet ◽  
Single Layer ◽  
Lateral Wall ◽  
The Body ◽  
Medial Wall ◽  
Microsurgical Anatomy ◽  
Pituitary Fossa ◽  
Adjacent Structures

Abstract OBJECTIVE: This study was conducted to clarify the boundaries, relationships, and components of the medial wall of the cavernous sinus (CS). METHODS: Forty CSs, examined under ×3 to ×40 magnification, were dissected from lateral to medial in a stepwise fashion to expose the medial wall. Four CSs were dissected starting from the midline to lateral. RESULTS: The medial wall of the CS has two parts: sellar and sphenoidal. The sellar part is a thin sheet that separates the pituitary fossa from the venous spaces in the CS. This part, although thin, provided a barrier without perforations or defects in all cadaveric specimens studied. The sphenoidal part is formed by the dura lining the carotid sulcus on the body of the sphenoid bone. In all of the cadaveric specimens, the medial wall seemed to be formed by a single layer of dura that could not be separated easily into two layers as could the lateral wall. The intracavernous carotid was determined to be in direct contact with the pituitary gland, being separated from it by only the thin sellar part of the medial wall in 52.5% of cases. In 39 of 40 CSs, the venous plexus and spaces in the CS extended into the narrow space between the intracavernous carotid and the dura lining the carotid sulcus, which forms the sphenoidal part of the medial wall. The lateral surface of the pituitary gland was divided axially into superior, middle and inferior thirds. The intracavernous carotid coursed lateral to some part of all the superior, middle, and inferior thirds in 27.5% of the CSs, along the inferior and middle thirds in 32.5%, along only the inferior third in 35%, and below the level of the gland and sellar floor in 5%. In 18 of the 40 CSs, the pituitary gland displaced the sellar part of the medial wall laterally and rested against the intracavernous carotid, and in 6 there was a tongue-like lateral protrusion of the gland that extended around a portion of the wall of the intracavernous carotid. No defects were observed in the sellar part of the medial wall, even in the presence of these protrusions. CONCLUSION: The CS has an identifiable medial wall that separates the CS from the sella and capsule of the pituitary gland. The medial wall has two segments, sellar and sphenoidal, and is formed by just one layer of dura that cannot be separated into two layers as can the lateral wall of the CS. In this study, the relationships between the medial wall and adjacent structures demonstrated a marked variability.

On the content of prolan in the pituitary gland

1934 ◽  
Vol 30 (6) ◽  
pp. 634-634
Author(s):  
P. Badul
Keyword(s):  
Pituitary Gland ◽  
Histological Examination ◽  
Anterior Lobe ◽  
Posterior Lobe ◽  
Posterior Pituitary ◽  
Posterior Pituitary Lobe

The posterior lobe of the pituitary gland in a bull is free of prolan, while in a human it contains prolan. Only here it can be found in that part of the posterior pituitary lobe adjacent to the anterior lobe. In the bull, too, this part of the pituitary gland is completely free of prolan content. Histological examination shows that in humans, this part of the posterior lobe is crossed by bands of cells from the anterior lobe, which consist exclusively of basophilic cells.

Diagnostic Imaging of Child Abuse

PEDIATRICS ◽  
1991 ◽  
Vol 87 (2) ◽  
pp. 262-264
Author(s):  
Keyword(s):  
Child Abuse ◽  
Diagnostic Imaging ◽  
Diagnostic Yield ◽  
Young Infant ◽  
Clinical Information ◽  
The Body ◽  
Pediatric Radiologist ◽  
Imaging Studies ◽  
Skeletal Injury ◽  
Infant And Young Child

The concept of child abuse as a medical entity has its origins in the radiologic studies of the pediatric radiologist Dr John Caffey, as well as many other specialists in the field of diagnostic imaging. When all cases of child abuse and neglect are studied, the incidence of physical alterations documentable by diagnostic imaging is relatively small. However, imaging studies are often critical in the infant and young child with evidence of physical injury, and they also may be the first indication of abuse in a child who is seen initially with an apparent natural illness. As most conventional imaging studies performed in this setting are noninvasive and entail minimal radiation risks, recommendations regarding imaging should focus on examinations, which provide the highest diagnostic yield at acceptable costs. SKELETAL IMAGING Although skeletal injuries rarely pose a threat to the life of the abused child, they are the strongest radiologic indicators of abuse. In fact, in the young infant, certain radiologic abnormalities are sufficiently characteristic to allow a firm diagnosis of inflicted injury in the absence of clinical information. This fact mandates that imaging surveys performed to identify skeletal injury be carried out with the same level of technical excellence utilized in examinations routinely performed to evaluate accidental injuries. The "body gram" or abbreviated skeletal surveys have no place in the imaging of these subtle, but highly specific bony abnormalities. In general, the radiographic skeletal survey is the method of choice for skeletal imaging in cases of suspected abuse. Modern pediatric imaging systems commonly use special film, cassettes, and intensifying screens to minimize exposure.

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