scholarly journals Prevalence and spectrum of dermatophytes in patients attending a tertiary care hospital Srinagar, Kashmir

2021 ◽  
Vol 9 (4) ◽  
pp. 1064
Author(s):  
Tabindah Jahan ◽  
Anjum Farhana ◽  
Farhat Kanth
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Clinical Samples ◽  
Fungal Culture ◽  
Care Hospital ◽  
Cultural Methods ◽  
Lower Socioeconomic ◽  
Fungal Distribution ◽  
Culture Positive

Background: Dermatophyte infections are a global health problem but very neglected in Kashmir. India. This work aimed at determining prevalence and spectrum of dermatophytosis isolated from patients attending tertiary care hospital Srinagar. Kashmir.Methods: A total of 510 samples of skin, hair and nail scrapings were collected and processed using standard microscopy (KOH) and cultural methods as per the standard protocol.Results: Out of 510 samples collected, 272 (53.33%) patients were confirmed cases of dermatophytosis (confirmed clinically and on fungal culture). The prevalence of dermatophytosis was significantly associated with age groups of participants with higher infection among those aged 18-32 which accounted for 35.29%, followed by age group 1-17 with 30.14%. Out of 510 samples, 110 ( 21.56%) were both KOH (microscopy) and culture positive, 162 (31.76%) cases were only culture positive and 130 (25.49%) clinical samples were only positive for fungal elements on microscopy. 133 (26.07%) fungal isolates were obtained which included both dermatophyte and non-dermatophytic fungi(excluded in this study). T. mentagrophytes had highest distribution 40.44% among dermatophytes species and T. Unguium 114 (41.96%) accounted for most common site for dermatophytic infections. Poor hygiene was predominant risk factor in 143 cases (52.57%). Patients from lower socioeconomic status were affected more than others (34.92%).Conclusions: In this study we have focused to determine the prevalence, clinical pattern and pathogenic profile of dermatophytosis according to the age, gender, site, and fungal distribution. Improvization of these conditions more accurately can result in decreased incidence of dermatophytosis in this area. 

Frequency and antibiogram of Acinetobacter species isolated from various clinical samples in a tertiary care hospital

2017 ◽  
Vol 4 (3) ◽  
pp. 263-268
Author(s):  
Tanu Arora ◽  
◽  
Shailpreet K Sidhu ◽  
Pushpa Devi ◽  
Sita Malhotra ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical Samples ◽  
Care Hospital ◽  
Acinetobacter Species

scholarly journals Prevalence of multidrug-resistant and extended-spectrum beta-lactamase producing Gram-negative isolates from clinical samples in a tertiary care hospital of Nepal

2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Aryatara Shilpakar ◽  
Mehraj Ansari ◽  
Kul Raj Rai ◽  
Ganesh Rai ◽  
Shiba Kumar Rai
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Polymyxin B ◽  
Multidrug Resistant ◽  
Confirmatory Test ◽  
Clinical Samples ◽  
Care Hospital ◽  
Gram Negative ◽  
Extended Spectrum ◽  
Esbl Producers

Abstract Background The existence of multidrug-resistant organisms, including extended-spectrum beta-lactamases (ESBLs), is on rise across the globe and is becoming a severe problem. Knowledge of the prevalence and antibiogram profile of such isolates is essential to develop an appropriate treatment methodology. This study aimed to study the prevalence of Gram-negative isolates exhibiting ESBL at a tertiary care hospital and study their antibiogram profile. Methods A cross-sectional study was conducted at Shahid Gangalal National Heart Centre, Kathmandu, Nepal, from June 2018 to November 2018. A total of 770 clinical samples were collected and identified using the conventional biochemical tests following the Clinical and Laboratory Standard Institute (CLSI) guidelines. Antimicrobial susceptibility testing (AST) was performed using the standardized Kirby-Bauer disk diffusion method. The screening test for ESBL producers was performed as recommended by the CLSI and the confirmatory test was performed phenotypically using the E-test. Results Out of the 92 isolates, 84 (91.3%) were multidrug-resistant, and 47 (51.1%) were found to be potential ESBL producers. Of these, 16 isolates were confirmed ESBL producers by the E-test. Escherichia coli and Klebsiella pneumoniae were the predominant isolates and were also the major ESBL producers. Besides polymyxin B (100% sensitive), meropenem and imipenem showed high efficacy against the ESBL producers. Conclusion Multidrug resistance was very high; however, ESBL production was low. Polymyxin B and carbapenems are the choice of drugs against ESBL producers but should be used only as the last line drugs.

scholarly journals Prevalence of Non-Albicans Candida Among the Patients Attending a Tertiary Care Hospital in Kathmandu, Nepal

2016 ◽  
Vol 4 (1) ◽  
pp. 43-46
Author(s):  
Manisha Sharma ◽  
Narayan Dutt Pant ◽  
Pratikshya Pandey
Keyword(s):  
Color Change ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Temperature Tolerance ◽  
Vaginal Swab ◽  
Clinical Samples ◽  
Care Hospital ◽  
Candida Spp ◽  
Test Characteristic ◽  
India Ink

The main objective of this study was to determine the prevalence of non-albicans Candida among the patients attending a tertiary care hospital in Kathmandu, Nepal. Candida spp. isolated from different clinical samples (sputum, urine, vaginal swab, blood, endotracheal (ET) secretion, pus) from 250 patients between the period of February 2013 and December 2015 were included in the study. Of those 250 patients, 20% were immunocompromised. Sabouraud dextrose agar was used for the isolation of Candida spp. and the identification was performed on the basis of colony morphology, Gram’s stain, India ink preparation, germ tube test, temperature tolerance test, characteristic color change in CHROMagar, chlamydospore production, sugar fermentation test and sugar assimilation test.Out of total 300 Candida spp., majority were isolated from sputum (43.33%) followed by urine (40%) and vaginal swab (6.67%). Of total 151 (50.33%) non-albicans Candida, the most common species isolated were C. tropicalis (62.25%) followed by C. glabrata (23.84%). High prevalence of non-albicans Candida among the patients attending a hospital in Kathmandu, Nepal was noted.

scholarly journals Susceptibility of Clinical Isolates of Staphylococcus aureus to Ceftaroline

2021 ◽  
Author(s):  
Harsha Sreedharan ◽  
KB Asha Pai
Keyword(s):  
Staphylococcus Aureus ◽  
Tertiary Care Hospital ◽  
Methicillin Resistance ◽  
Descriptive Analysis ◽  
Tertiary Care ◽  
The United States ◽  
Clinical Isolates ◽  
Diffusion Method ◽  
Clinical Samples ◽  
Care Hospital

Introduction: Methicillin-Resistant Staphylococcus aureus(MRSA) infection is a major global healthcare problem, the prevalence of which varies from 25-50% in India. It is known to cause Skin and Soft tissue Infections (SSI), endovascular infections, endocarditis, pneumonia, septic arthritis, osteomyelitis, and sepsis. Vancomycin is the drug of choice for treating severe MRSA infections. Ceftaroline, a fifth-generation cephalosporin has been approved by the United States Food and Drug Administration (US FDA) for treating acute bacterial SSI caused by susceptible micro-organisms including MRSA, Community acquired respiratory tract infection, MRSA bacteremia and endocarditis. Aim: To assess the susceptibility of clinical isolates of S. aureusto ceftaroline, in a Tertiary Care Hospital. Materials and Methods: This prospective study was conducted in the Department of Microbiology of a Tertiary Care Hospital over a period of two months from June 2019 to July 2019. S.aureus isolates from various clinical samples were screened for methicillin resistance by disc diffusion method using cefoxitin disc and ceftaroline susceptibility of these isolates was assessed by E-strip method. The isolates were classified as ceftaroline susceptible, Susceptibility Dose Dependent (SDD) and ceftaroline resistant respectively as per CLSI guidelines. A descriptive analysis of the data was done and the results were presented as frequencies and percentages. Results: All the S.aureus isolates were found to be susceptible to ceftaroline. Methicillin Sensitive Staphylococcus aureus(MSSA) isolates had lower Minimum Inhibitory Concentration (MIC) when compared to MRSA. The highest MIC among MRSA was 0.5 μg/mL. Conclusion: Ceftaroline can be considered as an effective alternative for treatment of infections caused by MRSA.

scholarly journals Impact of Running a Behavior Therapy Room for Various Categories of Urinary Incontinence Cases in Different Age Groups in Obstetrics-Gynecology Outpatient Department of a Tertiary Care Hospital

2014 ◽  
Vol 48 (4) ◽  
pp. 159-163
Author(s):  
Vanita Jain ◽  
Puja Dudeja
Keyword(s):  
Urinary Incontinence ◽  
Behavior Therapy ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Outpatient Department ◽  
Care Hospital ◽  
Kegel Exercises ◽  
Therapy Room ◽  
Trained Staff

ABSTRACT Introduction Urinary incontinence (UI) affects > 60% women. Its management is simple with the use of Kegel exercises. However, very few studies have been done in India about this problem and its solution. Objective To assess the impact of running a behavior therapy room (BTR) for various categories of UI cases in different age groups in obstetrics gynecology outpatient department (OBG-OPD) of a tertiary care hospital. Materials and methods Patients of UI were referred from gynecology OPD to BTR. There was trained staff available in BTR to teach Kegel exercises and related behavior therapy to the patients. Records of the patients were maintained. Follow-up was done through phone calls and personal visits of UI patients. Results A total of 251 cases were registered in BTR over 2 years. Overall 126 patients got relief from urine incontinence and prolapse of pelvic floor organs after BT. Conclusion Establishment of a separate room (BTR) with trained staff can be done in OBG department to teach Kegel exercises and to provide relief to women suffering from UI and pelvic organ prolapse (POP). Recommendation Behavior therapy room should be established in gynecology OPDs of all hospitals. How to cite this article Kaur T, Dudeja P, Sharma M, Jain V, Singh A. Impact of Running a Behavior Therapy Room for Various Categories of Urinary Incontinence Cases in Different Age Groups in Obstetrics-Gynecology Outpatient Department of a Tertiary Care Hospital. J Postgrad Med Edu Res 2014;48(4):159-163.

scholarly journals FREQUENCY AND CAUSES OF PERINATAL MORTALITY IN A TERTIARY CARE HOSPITAL IN PESHAWAR, PAKISTAN

2018 ◽  
Vol 16 (1) ◽  
pp. 15-19
Author(s):  
Maimoona Qadir ◽  
Sohail Amir ◽  
Samina Jadoon ◽  
Muhammad Marwat
Keyword(s):  
Mortality Rate ◽  
Perinatal Mortality ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Mortality Data ◽  
Care Hospital ◽  
Cross Sectional ◽  
Medical Disorders ◽  
Perinatal Mortality Rate

Background: Perinatal mortality rate indicates quality of care provided during pregnancy and delivery to the mother and to the neonate in its early neonatal period. The objective of this study was to determine the frequency and causes of perinatal mortality in a tertiary care hospital in Peshawar, Pakistan. Materials & Methods: This cross-sectional study was conducted at Department of Gynaecology & Obstetrics, Khyber Teaching Hospital, Peshawar, Pakistan from 1st January 2016 to 31st December 2016. The inclusion criteria was all singleton gestation with gestational age of at least 24 weeks presenting with perinatal mortality. Data was collected for the following variables; age groups (up to 20 years, 21-30 years, 31-40 years and > 40 years), booking status (yes/ no), period of gestation (24-31+6, 32-36+6, 37-39+6 and > 40 weeks), Foetal weight ( 3.5 kg) and cause of perinatal mortality. Results: Out of 4508 deliveries there were 288 perinatal deaths, including 228 stillbirths and 60 neonatal deaths, so perinatal mortality rate was 63.8/1000 births. 90.28% women were unbooked. Most common cause was hypertensive disorders of pregnancy (27.78%) followed by antepartum haemorrhage (25.71%) and then mechanical causes (13.88%). Congenital anomalies comprised 11.8% cases, neonatal problems 10.07% and maternal medical disorders for 4.16% cases. Cause of 4.16% cases remained unexplained. Conclusion: Appropriate strategies like control of identifiable causes, proper antenatal and postnatal care, healthy delivery practices and availability of emergency neonatal care facilities can bring down perinatal mortality rates.

scholarly journals Prevalence and antibiotic susceptibility pattern of Klebsiella species isolated from various clinical samples in a tertiary care hospital Coimbatore

2021 ◽  
Vol 8 (10) ◽  
pp. 4886
Author(s):  
Vijayashree V. ◽  
Saikeerthana D. ◽  
Prabha P.
Keyword(s):  
Antibiotic Susceptibility ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Clinical Samples ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Klebsiella Species ◽  
Antibiotic Susceptibility Pattern ◽  
Sensitivity Pattern

Background: The genus Klebsiella of Enterobacteriaceae family is ubiquitous in nature. They cause many nosocomial infections like pneumonia, urinary tract infections, wound infections, bacteremia and septicemia. Multidrug resistance is seen in Klebsiella which serves as the most common cause of increased morbidity and mortality. This study reveals the prevalence and antibiotic sensitivity pattern of Klebsiella species from various clinical samples. The primary objectives are as follows: To isolate and characterize Klebsiella species from various clinical samples. To study the antibiotic susceptibility pattern of Klebsiella isolates.Methods: This prospective study was conducted in our tertiary care hospital during the period from August 2019 to October 2019. A total of 3521 samples were tested during this period. The samples include blood, sputum, urine, and pus.Results: Out of the total samples tested,1106 samples were showing the growth of the organisms. Among this,351 were identified as Klebsiella species and the highest rate of isolation of Klebsiella species is from the sputum sample and also the same was reported high in medical wards. The study also shows that the isolation of Klebsiella species shows male preponderance when compared to females. The antibiotic sensitivity pattern was done by Kirby-Bauer's disc diffusion method and the sensitivity was noted to be higher to amikacin and ciprofloxacin.Conclusions: Thus, this study shows the prevalence rate of Klebsiella species and sensitivity pattern of Klebsiella, which may help select appropriate antibiotics and prevent overuse and misuse of antibiotics.

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