scholarly journals Intraventricular haemorrhage in very preterm neonates

2018 ◽  
Vol 5 (4) ◽  
pp. 1414
Author(s):  
Saurabh Kapoor ◽  
Ravi Sharma ◽  
Anil Kumar Sapare ◽  
Rajiv Aggarwal
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Neonatal Sepsis ◽  
Neonatal Intensive Care ◽  
Tertiary Care ◽  
Significant Risk ◽  
Intraventricular Haemorrhage ◽  
Preterm Neonates ◽  
Care Hospital

Background: The objective of the current study was to evaluate the incidence of intraventricular haemorrhage and its associated risk factors in preterm neonates.Methods: This cohort study done at Neonatal Intensive Care Unit of a tertiary care hospital in south India enrolled 104 preterm neonates with either gestational age <32weeks and/or birth weight <1500 grams at birth. These babies were serially screened for intraventricular haemorrhage by doing a neurosonogram on day3 and day 14 of life.Results: Incidence of IVH was found to be 18.2%. Amongst these cases 52.6% babies had Grade I, 36.8% babies had Grade II and 10.6% babies had Grade III intraventricular hemorrhage with ventriculomegaly, as per Papile grading system. It was seen that hypotension needing use of inotropes and neonatal sepsis were significantly associated with IVH.Conclusions: The incidence of IVH in babies born with gestational age <32weeks and/or birth weight <1500 grams was 18.2% in our study. Neonatal sepsis and hypotension requiring use of inotropes were found to be the significant risk factors in this population.

TO STUDY THE INCIDENCE AND RISK FACTORS OF RETINOPATHY OF PREMATURITY IN A TERTIARY CARE HOSPITAL IN NORTHERN INDIA

2021 ◽  
pp. 48-50
Author(s):  
Kajaldeep Kaur ◽  
Gursharn Singh
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Tertiary Care ◽  
Preterm Neonates ◽  
Care Hospital ◽  
Northern India ◽  
Retinal Examination

BACKGROUND: Retinopathy of prematurity (ROP) is a multifactorial retinal vaso-proliferative disorder which remains a leading cause of childhood blindness worldwide despite improvements in neonatal care and management guidelines. This study was conducted to determine the incidence of ROP among preterm neonates and to determine the risk factors. METHODS: All preterm infants with birth weight <1750 gm and gestation <34 weeks were screened for ROP at 4 weeks of birth for rst screening. Prenatal and postnatal risk factors, neonatal problems, treatment given, procedures and interventions done during stay in neonatal intensive care unit were recorded as per the proforma. The data from the study was systematically collected, compiled and statistically analyzed with SPSS Statistics-26 version to draw relevant conclusions. RESULTS: The incidence of ROP in 89 infants who were screened was 44%. The mean gestational age of babies with ROP was 32 weeks. In our study, pneumonia, apnea, sepsis, thrombocytopenia, NEC, shock, acidosis, IVH, BPD, the use of Bubble CPAP, Venti-CPAP and mechanical ventilator, the vasopressor use and blood transfusion were signicant risk factors. CONCLUSIONS: The incidence of ROP was signicantly higher in babies <34 weeks. It was observed in our that lower the birth weight and lower the gestational age, higher is the risk for the development of ROP. Careful and timed retinal examination of all at risk infants will minimize the development of ROP and later on blindness.

scholarly journals Retinopathy of Prematurity in A Tertiary Care Hospital in Eastern Nepal

2008 ◽  
Vol 47 (169) ◽  
Author(s):  
Srijana Adhikari ◽  
B P Badhu ◽  
N K Bhatta ◽  
R S Rajbhandari ◽  
B K Kalakheti
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Screening Criteria

World Health Organization’s Vision 2020 program has recognized Retinopathy of Prematurity(ROP) as an important cause of childhood blindness in industrialized and developing countries. Inthe last few years, it has been identifi ed in many under developed countries as well, as a result ofimproved neonatal intensive care. In Nepal, ROP screening is carried out in a few tertiary hospitalsbut there is no published data on this disease. The purpose of this study was to fi nd out the incidence,severity and risk factors of ROP among infants screened in a tertiary care hospital in the EasternRegion of Nepal.A prospective cohort study was carried out in neonates with gestational age of 34 weeks or less and,or birth weight of 1700 gm or less born over the period of one year. Dilated fundus examination ofall babies was done by indirect ophthalmoscopy between 2-4 weeks after birth and followed up tillthe retinal vascularization was complete. Classifi cation of ROP was done according to internationalclassifi cation (ICROP). Maternal and neonatal risk factors were also noted.A total of 55 babies fulfi lled the screening criteria. ROP was present in 25.45% (n=14) of the babies.Threshold disease was noted in 5.45% (n=3) of the babies screened. Low birth weight (p<0.01)and low gestational age (p<0.01) was signifi cantly associated with the incidence of ROP. Oxygensupplementation (p=<0.01) was an independent risk factor.ROP screening should be performed in all preterm low birth weight infants where there is availabilityof good neonatal intensive care units. The examination should be intensifi ed in those having riskfactors like oxygen. Further studies in the other tertiary care hospitals in Nepal would help toestablish the screening criteria for Nepalese infants.Key words: Retinopathy of prematurity, Eastern Nepal, screening

scholarly journals Retinopathy of prematurity: study of incidence, risk factors and outcome in level 3 neonatal intensive care unit in a tertiary care centre

2019 ◽  
Vol 7 (1) ◽  
pp. 90
Author(s):  
Uma Devi Rachamadugu ◽  
Sravani Devana ◽  
Srikanth Sandanala
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Tertiary Care ◽  
Preterm Neonates ◽  
P Value ◽  
Prospective Clinical Study ◽  
Tertiary Care Centre

Background: Advancing technology in antenatal and neonatal care has resulted in better survival of preterm neonates in developing countries in the past few decades. This has resulted in an apparent increase in the incidence of Retinopathy of Prematurity (ROP), which is the most important cause of preventable blindness in infants.Methods: A prospective clinical study was done for 18 months in 400 preterm babies less than 34 weeks of Gestational Age (GA) or less than 1750 gm of Birth Weight (BW). ROP screening was performed. The babies who developed any stage of ROP were taken as cases and the babies who did not have ROP were taken as controls. Statistical analysis was performed using SPSS software (Version 20.0). p value <0.05 was taken as statistically significant.Results: Four hundred babies were thus examined. The overall incidence of ROP in the study group was 10.25% (41 babies). Out of them, 38 babies (92.6%) had stage-1 ROP and 3 babies (7.31%) had stage-2 ROP. three babies (7.31%) required laser treatment. Risk factor analysis revealed that gestational age at birth, low birth weight, need foroxygenation, RDS, clinical sepsis, HIE, AKI, NNS, resuscitation, apnea.Conclusions: Screening should be intensified in the presence of risk factors like resuscitation, oxygen requirement, apnoea and prolonged hospital stay, which can reduce the incidence of severe stages of ROP as shown by this study.

scholarly journals Study of renal profile in septicemic neonates

2018 ◽  
Vol 5 (2) ◽  
pp. 448
Author(s):  
Sharwari J. Bhutada ◽  
Chandrakant M. Bokade
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Neonatal Sepsis ◽  
Age Of Onset ◽  
Tertiary Care ◽  
Neonatal Morbidity ◽  
Morbidity And Mortality ◽  
P Value ◽  
Etiological Agents

Background: Neonatal sepsis can cause multiorgan involvement causing neonatal morbidity and mortality. The kidneys are an important organ affected in septicemic newborns. In this study we evaluated the renal functions and its association with various risk factors along with outcome in septicemic neonates.Methods: This study was a prospective observational study conducted in a tertiary care teaching hospital. The sample size was 276 cases of septicemic new-borns and study duration was 2 years. The profile of acute renal failure (ARF) and various risk factors were studied in a sample of 276 septicemic neonates. Detailed clinical examination and investigations were done to confirm the diagnosis of neonatal sepsis and the occurrence of ARF was studied among these septicemic newborns. Risk factors like birth weight, gestational age, shock, etiological agents, DIC were studied for the occurrence of ARF and mortality in ARF patients among septicemic neonates.Results: 30.07% of septicemic neonates developed ARF. DIC (p value=0.014), shock (p value=<0.0001), gestational age (p value=0.005), birth weight (p value=0.003), were found to be analytically significant for the occurrence of ARF. Birth weight (p value=0.006), age of onset of sepsis (p value=0.019), shock (p value =<0.0001), oliguria (p value =<0.0001), and DIC (p value=0.015) were significant predictors of mortality in ARF among septicemic neonates.Conclusions: Awareness and early identification of various risk factors and ARF in septicemic neonates can prevent morbidity and mortality among neonates. 

scholarly journals Morbidities and Outcome of a Neonatal Intensive Care in Western Nepal

2017 ◽  
Vol 15 (2) ◽  
pp. 141-145 ◽  
Author(s):  
Sudhir Adhikari ◽  
Kalipatanam Seshagiri Rao ◽  
Ganesh B.K. ◽  
Namraj Bahadur
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Birth Weight ◽  
Neonatal Mortality ◽  
Neonatal Sepsis ◽  
Neonatal Intensive Care ◽  
Tertiary Care ◽  
Neonatal Hyperbilirubinemia ◽  
Preterm Neonates ◽  
Risk Of Mortality

Background: Neonatal mortality rate of developing countries is declining over decades. In the recent years increasing number of preterm and high risk neonates have facilities for tertiary care treatment. The aim of the study was to assess the morbidities and outcome of neonatal intensive care admissions.Methods: It was a retrospective observational study carried out in neonatal intensive care unit of the Manipal Teaching Hospital, Pokhara, Nepal from January 2014 to December 2015. Neonatal details including place of delivery, birth weight, gestation, diagnosis at admission, hospital course and final outcome were recorded in predesigned proforma. Risk of mortality was calculated using odds ratio and 95% confidence interval. Results: There were total 1708 admission during study period and inborn as well as out born neonates were equally admitted. Neonatal hyperbilirubinemia (37.1%), neonatal sepsis 532 (31.2%), prematurity, 314 (18.4%) perinatal asphyxia 112 (6.6%), meconium aspiration syndrome 79 (4.6%) and intrauterine growth restriction 49 (2.8%) were main indications for hospitalization. A total of 1410 (82.6%) the patients were discharged after treatment, 167 (9.7) left against medical advice, 115 (6.7%) died in hospital and 16 (1%) cases were referred. Preterm neonates had twice the risk of mortality than term neonates (OR =2.1664). Birth weight < 2500 grams had three times more risk of neonatal mortality than normal birth weight (OR =3.0783).Conclusions: Neonatal hyperbilirubinemia, prematurity and neonatal sepsis were common morbidities inneonatal intensive care unit.

scholarly journals Risk Factors for Mortality in Neonates with Birth Weight <1500 gm

2012 ◽  
Vol 2 (1) ◽  
pp. 19-22
Author(s):  
Md Abdul Baki ◽  
Afroza Haque ◽  
Fauzia Mohsin ◽  
Jebun Nahar ◽  
Shahida Akhter ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Univariate Analysis ◽  
Significant Risk ◽  
Preterm Neonates ◽  
Hospital Death ◽  
Study Population ◽  
Very High ◽  
Prevention Of Prematurity

Background and objective: Neonates with birth weight <1500 gm constitute approximately 4-7% of all live births. Mortality in this group is very high, contributing to as much as 30% of early neonatal death. This study was done to evaluate the morbidities associated with preterm neonates with birth weight < 1500 gm and possible factors determining the death of these babies. Methods: This study was done at Special Care Baby Unit (SCABU), BIRDEM Hospital from January to October 2010. The medical records of neonates with birth weight <1500 gm admitted in SCABU during the study period were retrospectively reviewed. The outcome measure was in-hospital death. Univariate analysis was done to determine the risk factors of mortality. Results: Total 64 babies with birth weight <1500 gm were admitted during this study period. Mean gestational age was 30.76 (± 2.97) weeks, mean birth weight was 1182 (±283) gm. Jaundice (59.4%), Thrombocytopenia (57.8%), apnoea (53.15), sepsis (45.3%) feeding intolerance (43.8%), and RDS (23.4%) were common co-morbidities in these neonates. Among 64 babies more than one-third died (36%). Risk factors for mortality were gestational age less than 30 wks (OR: 7.73; 95% CI: 2.43-24.53), weight <1000 gm (OR: 4.93; 95% CI: 1.28-18.87), RDS (OR: 13.81; 95% CI: 13.81- 57.86) and baby who required mechanical ventilation (OR: 61.66; 95% CI: 12.54- 303.22). Conclusion: Extreme low birth weight (birth weight <1000 gm), prematurity (gestational age <30 wks) and RDS were the significant risk factors for mortality in this study population. Prevention of prematurity and appropriate management of RDS may reduce the mortality of these neonates. DOI: http://dx.doi.org/10.3329/birdem.v2i1.12356 Birdem Med J 2012; 2(1) 19-22

scholarly journals A study of the incidence of retinopathy of prematurity in a tertiary care centre in Karnataka

2021 ◽  
Vol 8 (6) ◽  
pp. 1033
Author(s):  
Manjunathaswmy R. ◽  
Anjana H. Rao ◽  
Vinayaka P. Hegade ◽  
Pradeep Kumar ◽  
Ravindra B. Patil
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Tertiary Care ◽  
Argon Laser ◽  
Preterm Neonates ◽  
Multiple Gestation ◽  
Care Centre ◽  
Tertiary Care Centre

Background: Retinopathy of prematurity is a preventable cause of childhood blindness. Proper understanding of the classification, risk factors and treatment methods is a must in tackling this disease. The aim of this study was to know the incidence of ROP in preterm infants in a tertiary care centre and to improvise the selection criteria in future in Indian babies.Methods: A retrospective study of all infants admitted to the NICU from 2016 to 2018 who met the criteria for ROP screening were included in the study. Examination of the eyes was done by a trained technician using a Ret Cam digital imaging in collaboration with KIDROP, Narayana Nethralaya and later interpreted by trained ophthalmologists using the concept of teleopthalmology. Babies were followed up and screened accordingly. Qualified infants were treated with argon laser photocoagulation within 48h of diagnosis. They were followed until the disease was successfully treated.Results: In current study, incidence of ROP was found to be 10.2%. The gestational age ranged from 28-36 weeks with a mean of 30.5±1.5 weeks. In current study, the most prevalent prenatal risk factor was multiple gestation and postnatal risk factors was anemia, low birth weight ,low gestational age and the use of oxygen therapy.Conclusions: Screening for ROP, in India, should be performed in all preterm neonates who are born <34 weeks gestation and/or <1800 grams birth weight; as well as in babies 34-36 weeks gestation or 1800-2000 grams birth weight if they have risk factors for ROP.

scholarly journals Incidence and risk factors of retinopathy of prematurity in Goa, India: a report from tertiary care centre

2019 ◽  
Vol 6 (3) ◽  
pp. 1228
Author(s):  
Sarvesh Kossambe ◽  
Shilpa Joglekar ◽  
Annely D'lima ◽  
M. P. Silveira
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Laser Photocoagulation ◽  
Very Low Birth Weight ◽  
Care Center ◽  
Tertiary Care ◽  
Preterm Neonates ◽  
Tertiary Care Centre

Background: To report the incidence and risk factors leading to the development of retinopathy of prematurity (ROP) from a tertiary care center in the western Indian state of Goa, India.Methods: This was a prospective observational study carried out in a level II neonatal intensive care unit (NICU) for a period of 18 months. Babies born at < 34 weeks’ gestation and having a birth weight of <1500gm were screened for ROP and laser photocoagulation was done for those who developed threshold ROP. Group differences between any ROP and threshold ROP were analysed using the chi-square test.Results: Out of the 244 preterm neonates screened, 37 developed ROP (15.16%), and 14 out of them (5.73%) developed threshold ROP requiring laser photocoagulation. Very low birth weight, prematurity, apnea, anemia, sepsis, respiratory distress syndrome, bronchopulmonary dysplasia, blood transfusions, exchange transfusions and days taken to reach full enteral feeds and regain birth weight were significantly associated with the development of ROP.Conclusions: This is the first report of ROP from Goa where less than 1 in 5 babies developed ROP. This is similar to that reported across the rest of the country. Judicious oxygen use, ventilation strategies, transfusions guidelines, control of sepsis, early enteral feeds and adequate nutrition may help prevent the development of ROP in the future.

scholarly journals The Incidence and Risk Factors of Retinopathy of Prematurity in Sick Newborn Care Unit in a Tertiary Care Hospital in Eastern India - A Cross-Sectional Observational Study

2021 ◽  
Vol 8 (18) ◽  
pp. 1299-1303
Author(s):  
Pinaki Sengupta ◽  
Sheuli Kumar ◽  
Mohua Mazumdar ◽  
Soumyadeep Majumdar ◽  
Manideepa Pande
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Oxygen Therapy ◽  
Low Birthweight ◽  
Tertiary Care ◽  
Newborn Care ◽  
Care Hospital ◽  
Cross Sectional

BACKGROUND Retinopathy of prematurity (ROP) is one of the leading causes of ocular morbidity and mortality throughout the world. Prematurity, low–birth, and oxygen therapy are considered to be the common risk factors. The maldeveloped retina in those affected are very much prone to develop refractive error, neo-vasculopathy, and neurosensory detachment. The purpose of our study was to find out the incidence and ascertain the risk factors of retinopathy of prematurity among the neonates attending the sick neonatal care unit and OPD of Calcutta National Medical College & Hospital. METHODS This is an institution based cross-sectional observational study conducted in the sick newborn care unit of a tertiary care hospital. Informed consent was obtained from the parents along with proper birth history. Indirect ophthalmoscopy with a + 20 dioptre (+ 20 D) lens with a paediatric scleral depressor was performed in each eye under the guidance of the neonatologist after pupillary dilatation. If either eye was found to have ROP, the baby was considered as an ROP case in the study and each eye was considered as a single case. RESULTS 50.27 % babies (N = 91) were delivered by Lower Uterine Segment Caesarean Section (LSCS) and 55. 24 % babies were < 32 weeks of gestational age whereas 21.45 % (N = 39) babies were having < 1500 gm birth weight. Phototherapy was needed in 50 % of the babies (N = 92) whereas hyperbilirubinemia was present in 59.66 % of total babies. Bradycardia, apnoea, and sepsis were present in 29.83 % (N = 54), 25.41 % (N = 46), 41.98 % (N = 76) of the babies respectively. When compared in the two independent groups (ROP present and absent), low gestational age and low birth weight of the babies were found to be statistically significant (P < 0.05) for the development of ROP. After adjusting with different factors in the regression model we have found that low birth weight and oxygen therapy after birth were statistically significant with the development of ROP (P < 0.05). CONCLUSIONS ROP screening, specifically for those babies with low-birthweight, low gestational age, and those who received oxygen therapy for other systemic reasons, is mandatory to have an early diagnosis and treatment done. KEYWORDS ROP, Low-Birthweight, Gestational Age, Oxygen Therapy

scholarly journals Factors Associated with the Death of Preterm Babies Admitted to Neonatal Intensive Care Units in Ethiopia: A Prospective, Cross-sectional, and Observational Study

2020 ◽  
Vol 7 ◽  
pp. 2333794X2097000
Author(s):  
Amha Mekasha ◽  
Zelalem Tazu ◽  
Lulu Muhe ◽  
Mahlet Abayneh ◽  
Goitom Gebreyesus ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Gestational Age ◽  
Neonatal Intensive Care ◽  
Significant Risk ◽  
High Rate ◽  
Preterm Neonates ◽  
Cross Sectional ◽  
Data Set ◽  
Tertiary Hospitals

Aim. To determine the risk factors for death among preterm neonates. Methods and materials. The data set used was derived from a prospective, multi-center, observational clinical study conducted in 5 tertiary hospitals in Ethiopia from July, 2016 to May, 2018. Subjects were infants admitted into neonatal intensive care unit. Results. Risk factors were determined using statistical model developed for this study. The mean gestational age was 32.87 (SD ± 2.42) weeks with a range of 20 to 36 weeks. There were 2667 (70.69%) survivors and 1106 (29.31%) deaths. The significant risk factors for preterm death were low gestational age, low birth weight, being female, feeding problem, no antenatal care visits and vaginal delivery among mothers with higher educational level. Conclusions. The study identified several risk factors for death among preterm neonates. Most of the risk factors are preventable. Thus, it is important to address neonatal and maternal factors identified in this study through appropriate ANC and optimum infant medical care and feeding practices to decrease the high rate of preterm death.

Sign in / Sign up

Export Citation Format

Share Document