scholarly journals Co-infection of COVID-19 and dengue: a case report

2021 ◽  
Vol 8 (8) ◽  
pp. 1213
Author(s):  
Desak P. G. S. Seputra ◽  
Kadek S. D. Saraswati ◽  
Anak A. I. S. K. Dewi
Keyword(s):  
Health Care Workers ◽  
Dengue Infection ◽  
Regional Hospital ◽  
World Region ◽  
Global Pandemic ◽  
Care Workers ◽  
The World ◽  
Dual Burden ◽  
Diagnostic Delays ◽  
Improve Clinical Outcome

COVID-19 has now spread to most countries, causing a global pandemic. As the COVID-19 pandemic is still ongoing, some part of the world region with tropical climate is facing a dual burden of infection with the presence of concurrent endemic infectious disease. This endemic dengue infection and the COVID-19 pandemic may turn out into a fatal and hazardous combination. In addition, dengue and COVID-19 possess clinical and laboratory features that are sometimes difficult to differentiate. The possibility of COVID-19 and dengue co-infection has also been a noticeable issue. We present a case of 19-year-old male with COVID-19 and dengue co-infection admitted at Wangaya Regional Hospital Denpasar, Bali. Co-infection of COVID-19 and dengue requires special attention from all health care workers in dengue-endemic countries in order to avoid diagnostic delays and improve clinical outcome. It is also necessary to conduct further research which explores the potential of co-infection between coronavirus and arbovirus. 

scholarly journals Standardised, quantitative neutralisation responses to SARS-CoV-2 Variants of Concern by convalescent anti-sera from first wave infections of UK Health Care Workers and Patients

2021 ◽  
Author(s):  
Diego Cantoni ◽  
Martin Mayora-Neto ◽  
Angalee Nadesalingam ◽  
David A. Wells ◽  
George W. Carnell ◽  
...  
Keyword(s):  
Health Care Workers ◽  
Healthcare Workers ◽  
World Health Organisation ◽  
World Health ◽  
Care Centre ◽  
International Standard ◽  
Care Workers ◽  
The World ◽  
Antibody Titres ◽  
The Uk

One of the defining criteria of Variants of Concern (VOC) is their ability to evade pre-existing immunity, increased transmissibility, morbidity and/or mortality. Here we examine the capacity of convalescent plasma, from a well defined cohort of healthcare workers (HCW) and Patients infected during the first wave from a national critical care centre in the UK, to neutralise B.1.1.298 variant and three VOCs; B.1.1.7, B.1.351 and P.1. Furthermore, to enable lab to lab, country to country comparisons we utilised the World Health Organisation (WHO) International Standard for anti-SARS-CoV-2 Immunoglobulin to report neutralisation findings in International Units. These findings demonstrate a significant reduction in the ability of first wave convalescent plasma to neutralise the VOCs. In addition, Patients and HCWs with more severe COVID-19 were found to have higher antibody titres and to neutralise the VOCs more effectively than individuals with milder symptoms. Widespread use of the WHO International Standard by laboratories in different countries will allow for cross-laboratory comparisons, to benchmark and to establish thresholds of protection against SARS-CoV-2 and levels of immunity in different settings and countries.

scholarly journals COVID-19: first long-term care facility outbreak in the Netherlands following cross-border introduction from Germany, March 2020

2020 ◽  
Author(s):  
Mitch van Hensbergen ◽  
Casper D.J. den Heijer ◽  
Petra Wolffs ◽  
Volker Hackert ◽  
Henriette L.G. ter Waarbeek ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Long Term Care ◽  
Care Facility ◽  
Regional Hospital ◽  
Term Care ◽  
Long Term Care Facility ◽  
Cross Border ◽  
Care Workers

Abstract Background: The Dutch province of Limburg borders the German district of Heinsberg, which had a large cluster of COVID-19 cases linked to local carnival activities in February, before any cases were reported in the Netherlands. However, Heinsberg was not included as an area reporting local or community transmission per the national case definition at the time. In early March, two residents from a long-term care facility (LTCF) in Sittard, a Dutch town located in close vicinity to the district of Heinsberg, started experiencing respiratory symptoms and were admitted to the regional hospital at which they were tested for COVID-19. Introduction of the virus could have occurred following the carnival activities in the surrounding area by LTCF visitors or health care workers.Methods: Surveys and semi-structured oral interviews were conducted with all present residents by health care workers during regular points of care for information on new or unusual signs and symptoms of disease. Both throat and nasopharyngeal swabs were taken from residents suspect of COVID-19 for the detection of SARS-CoV-2 by Real-time Polymerase Chain Reaction and whole genome sequencing was performed using a SARS-CoV-2 specific amplicon-based Nanopore sequencing approach. Additionally, twelve random residents were sampled for possible asymptomatic infections.Results: Since the start of the outbreak, nineteen (19%) residents tested positive for COVID-19. Eleven samples were sequenced, along with three random samples from COVID-19 patients hospitalized in the regional hospital at the time of the LTCF outbreak. Conclusions: All samples were linked to COVID-19 cases from the cross-border region of Heinsberg, Germany. Symptoms were reported only in about two third of the cases, and tended to be generally mild. We therefore recommend low-level screening of HCWs and residents following a confirmed COVID-19 case, even in the absence of symptoms. Since the LTCF residents who tested positive did not meet the criteria for suspect cases of COVID-19 at the time, this highlights the importance of cooperation among cross-border partners in order to establish a coordinated implementation of infection control measures in the region on top of national guidelines to limit the spread of infectious diseases such as COVID-19.

scholarly journals Modeling Predictive Age-Dependent and Age-Independent Symptoms and Comorbidities of Patients Seeking Treatment for COVID-19: Model Development and Validation Study (Preprint)

2020 ◽  
Author(s):  
Yingxiang Huang ◽  
Dina Radenkovic ◽  
Kevin Perez ◽  
Kari Nadeau ◽  
Eric Verdin ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Predictive Models ◽  
Model Development ◽  
Hospital Setting ◽  
World Health ◽  
Medical Attention ◽  
Age Related ◽  
Care Workers ◽  
The World

BACKGROUND The COVID-19 pandemic continues to ravage and burden hospitals around the world. The epidemic started in Wuhan, China, and was subsequently recognized by the World Health Organization as an international public health emergency and declared a pandemic in March 2020. Since then, the disruptions caused by the COVID-19 pandemic have had an unparalleled effect on all aspects of life. OBJECTIVE With increasing total hospitalization and intensive care unit admissions, a better understanding of features related to patients with COVID-19 could help health care workers stratify patients based on the risk of developing a more severe case of COVID-19. Using predictive models, we strive to select the features that are most associated with more severe cases of COVID-19. METHODS Over 3 million participants reported their potential symptoms of COVID-19, along with their comorbidities and demographic information, on a smartphone-based app. Using data from the >10,000 individuals who indicated that they had tested positive for COVID-19 in the United Kingdom, we leveraged the Elastic Net regularized binary classifier to derive the predictors that are most correlated with users having a severe enough case of COVID-19 to seek treatment in a hospital setting. We then analyzed such features in relation to age and other demographics and their longitudinal trend. RESULTS The most predictive features found include fever, use of immunosuppressant medication, use of a mobility aid, shortness of breath, and severe fatigue. Such features are age-related, and some are disproportionally high in minority populations. CONCLUSIONS Predictors selected from the predictive models can be used to stratify patients into groups based on how much medical attention they are expected to require. This could help health care workers devote valuable resources to prevent the escalation of the disease in vulnerable populations.

scholarly journals Use of face mask in COVID-19 pandemic-a review

2021 ◽  
Vol 9 (12) ◽  
pp. 3750
Author(s):  
Santosh Kumar Swain ◽  
Pragnya Paramita Jena
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Virus Disease ◽  
Minimum Cost ◽  
Face Mask ◽  
Medical Community ◽  
Care Workers ◽  
Surgical Masks ◽  
The World ◽  
The Face

The current novel corona virus disease 2019 (COVID-19) is a highly infectious disease of the respiratory tract and rapidly spreading all over the world in short span of time. In current COVID-19 pandemic, use of the face mask is becoming usual and ubiquitous for both health care workers and public individuals. Wearing face mask is one of the non-pharmaceutical interventions which need minimum cost and provide dramatic response for preventing the COVID-19 infection. Limited availability of the vaccine and inadequate supply of therapeutic options, face mask use is an important part for public health measures for restricting the COVID-19 spread. Regardless of the debate among medical community regarding global face mask production shortage, a greater number of countries in the world are moving ahead with recommendations or mandates for using face mask in public. As currently global shortage of N95/FFP2 respirators and surgical masks for use by health care workers in the hospitals, simple cloth masks will act as a pragmatic solution for the use of the public. General public often use the surgical mask or even filtering facepiece (FFP) masks irrespective of their need, resulting unnecessary shortage for needy individuals those are exposed to the patients or those are health care workers. So, this review article will clarify the indication of the different types of masks and their rational use in the current COVID-19 pandemic.

scholarly journals A Review of Potential Antiviral Drugs and Vaccines to Treat COVID-19

2020 ◽  
Vol 14 (suppl 1) ◽  
pp. 765-774
Author(s):  
Sanjeet Singh ◽  
Jayaram R.
Keyword(s):  
Health Care Workers ◽  
Social Life ◽  
Patient Monitoring ◽  
Web Of Science ◽  
Drug Repurposing ◽  
Patient Handling ◽  
Care Workers ◽  
The World ◽  
Muscle Ache

Coronavirus disease 19 (COVID-19) is a challenge to the whole humanity. COVID-19 was first reported in China and rigorous researches are going on for developing vaccine for the pandemic. This review was prepared by following PRISMA guidelines and used the resources from the Web of Science and PubMed. This research focuses on the niches of symptoms and vaccines for COVID-19. The research for vaccine involves research for new vaccine and drug repurposing. Out of various drug repurposing options, Remdesivir, and Favipiravir, Chloroquine and Lopinavir/Ritonavir were found to be the popular ones for treating COVID-19 patients across the world. Even though there are concerns regarding asymptotic patients, the most dominant symptoms of COVID-19 are fever and cough, followed by Dyspnoea and muscle ache. This review concludes that the COVID-19 related research should focus on developing immunity vaccines, and repurposing of drugs. Research on the problems of quarantine life, patient monitoring, and usage of information technology in facing COVID-19 will improve the quality of patient handling during the pandemic. The research on the effectiveness of various models of lockdown and regulation of social life during lockdown periods, improving the safety of health care workers in the workplace will definitely help the governments in their fight against COVID-19.

scholarly journals Disability Training for Health Care Workers: A Global Narrative Systematic Review

2021 ◽  
Author(s):  
Sara Rotenberg ◽  
Danae Rodriguez Gatta ◽  
Azizia Wahedi ◽  
Rachelle Loo ◽  
Emily McFadden ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Health Care Workers ◽  
Self Efficacy ◽  
Health Workers ◽  
Continuing Professional Development ◽  
People With Disabilities ◽  
Care Workers ◽  
The World ◽  
Training Community

Objective: To conduct a systematic review of the literature on disability training to improve knowledge, confidence, self-efficacy and competence among health care workers around the world. Methods: We searched five databases for relevant peer-reviewed articles published between January 2012 and January 2021. Studies that focused on training health care workers to improve knowledge, confidence, self-efficacy, and competence to support people with physical, sensory, or intellectual impairments were included. Data about the details of the intervention (setting, participants, format, impact assessments, etc.) and its effects were extracted. Findings: There is an array of highly local tools to train health workers across stages of their training and careers (pre-service, in-service, and continuing professional development). Studies involving people with disabilities in the training, community placements, simulations, or interactive sessions were found to be most effective in improving knowledge, confidence, competency, and self-efficacy. Conclusion: As part of initiatives to build inclusive health systems and improve health outcomes for people with disabilities, health workers around the world need to receive appropriate and evidence-based training that combine multiple methods and involve people with disabilities.

scholarly journals An Acute Pulmonary Coccidioidomycosis Coinfection in a Patient Presenting With Multifocal Pneumonia With COVID-19

2020 ◽  
Vol 8 ◽  
pp. 232470962097224
Author(s):  
Cameron Casey Chang ◽  
Randolph Senining ◽  
Jessica Kim ◽  
Rajan Goyal
Keyword(s):  
Health Care ◽  
Case Report ◽  
Respiratory Distress ◽  
Health Care Workers ◽  
Endemic Diseases ◽  
Care Workers ◽  
Pulmonary Manifestations ◽  
The World

The ongoing coronavirus disease-2019 (COVID-19) pandemic has been the focus of health care workers as it has affected millions of people and cost hundreds of thousands of lives around the world. As hospitals struggle to identify and care for those afflicted with COVID-19, it is easy to overlook endemic diseases that potentially worsen or mimic the pulmonary manifestations or may coinfect those with COVID-19. In this case report, we present the case of a 48-year-old Hispanic female who was admitted with respiratory distress from an acute COVID-19 infection but was also found to have acute pulmonary coccidioidomycosis infection and was treated successfully.

Can the Use of Bedside Lung Ultrasound Reduce Transmission Rates in The Case of The COVID-19 Patient? - A Narrative Review

POCUS Journal ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 26-28
Author(s):  
Sheena Bhimji-Hewitt MAppSc; DMS, CRGS, RDMS
Keyword(s):  
Health Care Workers ◽  
Lung Ultrasound ◽  
Virus Disease ◽  
Viral Disease ◽  
World Health ◽  
Rapid Review ◽  
Limited Information ◽  
Care Workers ◽  
The World ◽  
Health Organization

Novel Corona Virus Disease-19 (nCov-19, COVID-19) was recognised as a pandemic by the World Health Organization on March 11, 2020. As of June 14, 2020, this contagious viral disease has afflicted 188 out of 195 countries in the world with 7,893,700 confirmed cases and 432,922 global deaths. Canada has 98,787 people infected and 8,146 deaths. COVID-19 is thought to transmit through contact, droplets and aerosolization. A rapid review showed limited information on the benefits of conducting lung ultrasound (LUS) versus chest radiograph (CXR) or studies correlating lung ultrasound to chest computed Tomography (CT) in patients positive for Covid-19. The literature review confirmed that CT and LUS cannot diagnose this disease, but that both can help in the management and staging of this disease. There is no literature to prove that LUS at the bedside may be beneficial from the view of decreased transmission to other health care workers and bystanders due to reduced transit but comparing the transit pathway and contact leads one to propose that this would be so. Pregnant patients with COVID-19, young children and patients in the reproductive stage would also benefit from LUS since there is no radiation dose and the critical patient in distress will benefit from testing at the bedside.

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