scholarly journals Adherence to anti-retroviral therapy and factors influencing it among HIV/AIDS adult patients in Agra: a cross-sectional study

Author(s):  
Sunil Kumar Meena ◽  
Rudresh Negi ◽  
Shailendra Singh Chaudhary ◽  
Sunil Kumar Misra

Background: HIV/AIDS remains a significant global public health problem. With approximately 56% HIV patients in India receiving treatment, adherence to drugs is a crucial element for successful management. Sustainable development goals, National Strategic plan for HIV/AIDS and STI (2017-24) and 90-90-90 target pushing towards ending of AIDS epidemic require adequate adherence and this research estimates the adherence, associated factors and reasons for non-compliance.Methods: This analytical cross sectional study was undertaken on 160 HIV patients from an ART Centre. A pre-structured, pilot tested, face validated questionnaire was used and data collected by face to face interviews, through random selection of participants from outpatient department register. Data was analysed using Epi Info software and chi squared test applied.Results: Of the 160 study subjects, 86.8% remained adherent to the treatment with forgetfulness (71.4%) being the most common cause for non-adherence. Statistically significant treatment adherence was observed to be associated with socio-economic status (p=0.021) and period elapsed since diagnosis (p=0.041).Conclusions: Improving adherence to drug therapy through intensive counselling, streamlined drug supply and increased family participation would go a long way in reducing the menace of HIV. 

2019 ◽  
Author(s):  
Demelash Wachamo ◽  
Fisseha Bonja

Abstract Background Opportunistic infections are late complications of HIV infection is the depletion of the immune system. It is a major public health problem and high morbidity AIDS patients die of AIDS-related infections in developing countries like Ethiopia. Identification of opportunistic infections (OIs) is important to develop a specific intervention. Therefore, this study aimed to assess the burden and associated factors of opportunistic infections.Method A facility-based cross-sectional study was conducted on 420 randomly selected HIV/AIDS patients taking anti-retroviral therapy. Data was collected from selected hospitals in Sidama Zone based on population proportion to size. Data was collected by a pre-tested questionnaire and a pre-tested checklist from the medical records of patients. Data entry and analyzed for descriptive and logistic regression models by SPSS v.23. The result declared as statistically significant at p < 0.05.Result The magnitude of opportunistic infections was 39.6%. Major identified OIs was oral candidacies 23.2%, recurrent bacterial pneumonia 21.5%, Herpes zoster 6.3%, and Pulmonary Tuberculosis 6.0%.The magnitude of opportunistic associated with; older age [AOR=2.69, 95% CI: 1.33-5.43], No formal education [AOR=3.12, 95% CI: 1.06-9.25], Low monthly income [AOR=2.27, 95%CI:1.35-3.83], initial CD4 count less than 200 cells/mm3 [AOR=1.91, 95% CI:1.05-3.46), WHO clinical stage II [AOR=2.43, 95% CI:1.34-4.42] and stage III and IV [AOR=4.27, 95% CI: 2.12-8.59], had no extra medicine additional to ART (prophylaxis) had [AOR= 5.91, 95% CI: 3.31-10.56], who interrupt ART medicines [AOR=2.03, 95% CI: 1.09- 3.80] and Khat chewing [AOR=5.48, 95% CI: 2.32-12.96] when compared to their counterparts.Conclusions The overall magnitude of opportunistic infections was high when compared with other studies. Health officials and clinicians need to give attention on the strengthening of the provision if ART with prophylaxis on early-stage and adhrerence, implementation of the TB/HIV collaboration activity, and early initiation of ART to reduce opportunistic infections.


2020 ◽  
Vol 29 (4) ◽  
Author(s):  
Nur Ramadhan ◽  
Yulidar Yulidar ◽  
Abidah Nur ◽  
Zain Hadifah ◽  
Yasir Yasir

Abstract Filariasis is still a global public health problem both in the world and in Indonesia. Aceh is include in one of the provinces with the most clinical cases in Indonesia. The aimed of this study was to determine the description of endemicity status and Related Factors to Instantaneous Transmissions period after Transmission Assessment Survey (TAS) 1 in Pidie district. This research is part of the filariasis elimination evaluation study in Indonesia (Multicenter Filariasis Study) Litbangkes Office Center, Ministry of Health in 2017. The research design was cross sectional study. The study was conducted from February to November 2017. The selected research sites were Buloh and Kambuk Payapi Village in Pidie district. Data was collected by interviewin respondent to obtained information about people's knowledge, attitudes and behavior related to filariasis. In addition, finger blood tests were also conducted on respondents who had been interviewed. The number of respondents by finger blood was 627 and 714 were interviewed. The risk of filariasis transmission still occurred with the finding of 10 positive cases of microfilaria as many as 10 people in Kambuk Payapi village  with B.malayi species. The average filarial density was 86.84 / μl blood.  Respondent’s knowledge about filariasis is still low, community attitudes towads the prevention and treatment of filariasis was positive. Only a portion of respondents were involved in mass treatment. Selective treatment and strengthening synergy across sectors and programs must be increased so that elimination of  filariasis can be achieved. In addition, it is necessary to increase public knowledge through various health promotion media to improve community behaviour to achieve  elimination of filariasis. Abstrak Filariasis masih menjadi masalah kesehatan baik di dunia maupun di Indonesia. Aceh termasuk dalam salah satu provinsi dengan kasus klinis kronis terbanyak di Indonesia. Tujuan penelitian ini adalah mengetahui gambaran status endemisitas filariasis dan faktor yang berpengaruh dengan transmisi setelah Transmission Assessment Survey (TAS) 1 di Kabupaten Pidie. Penelitian ini merupakan bagian dari studi evaluasi eliminasi filariasis di Indonesia (studi Multicenter Filariasis) Badan Litbangkes Kementerian Kesehatan tahun 2017. Desain penelitian adalah cross sectional study. Penelitian dilakukan dari Februari-November 2017. Tempat penelitian adalah di desa Buloh dan desa Kambuk Payapi di Kabupaten Pidie. Pengumpulan data dilakukan wawancara responden untuk mendapatkan informasi tentang pengetahuan, sikap, dan perilaku masyarakat terkait filariasis. Selain itu juga dilakukan pemeriksaan darah jari malam hari pada responden yang sudah diwawancarai.  Jumlah responden yang diperiksa darah jari 627 responden dan yang diwawancarai 714.  Resiko penularan filariasis masih terjadi dengan masih ditemukannya kasus positif mikrofilaria sebanyak 10 orang di desa Kambuk Payapi dengan spesies B.malayi. Rata-rata kepadatan filaria adalah 86,84/µl darah. Pengetahuan responden tentang penyebab filariasis masih rendah, sikap masyarakat terhadap upaya pencegahan dan pengobatan filariasis sudah positif. Namun demikian hanya sebagian responden yang ikut terlibat dalam pengobatan masal. Pengobatan selektif dan memperkuat sinergi lintas sektos dan lintas program harus ditingkatkan agar eliminasi filariasis dapat dicapai. Selain itu diperlukan peningkatan pengetahuan masyarakat melalui berbagai media promosi kesehatan untuk meningkatkan prilaku masyarakat untuk mencapai eliminasi filariasis.  


2017 ◽  
Vol 4 (2) ◽  
pp. 317
Author(s):  
Haleema Nuwera ◽  
Anitha S. Prabhu

Background: HIV an abbreviation of human immunodeficiency virus, infection of which in most advanced stage leads to AIDS. HIV/AIDS is both global public health problem and young people are at the centre of global HIV/AIDS pandemic. Lack of information and understanding about HIV/AIDS, increases their susceptibility towards the disease. Hence, this study was conducted to assess the knowledge of HIV/AIDS among the X grade students as well as to know the differences in knowledge across gender.Methods: A cross sectional study was conducted among 250 students studying in X grade of 3 private schools located in Mangalore city, selected by multistage cluster sampling. The study was conducted for duration of 2 weeks using a predesigned and pre-structured questionnaire. Ethical approval from the institution and necessary permission from school authority was obtained prior to initiation of study. Results: Mean age of the study participants was 15.40±0.615. Females were predominant in the age group of 14 and 16 years (100.0% and 53.40% respectively). Majority of them had adequate knowledge of full form of HIV (94.4%), virus as causative agent (85.6%), awareness symbol of HIV/AIDS (86.8%), modes of transmission of HIV (871.6%). Poor knowledge was observed in areas of prevention (60.4%), actions that does not transmit HIV infection (58.0%), availability of blood tests (58.0%) and drugs (42.4%). Males had better knowledge in various areas when compared to females.Conclusions: Stringent efforts are required to improve the knowledge of HIV/AIDS by health education camps and school teachers need to be trained to enhance the knowledge of students.


Author(s):  
T. K. Raja ◽  
T. Muthukumar ◽  
Anisha Mohan P.

Background: Hypertension is one of the non-communicable diseases, which is an important global public health problem and also the most leading cause for cardiovascular disease in both developed and developing countries. The aim and objectives of the study were to estimate the prevalence of hypertension and to assess the associated risk factors among adults of rural population.Methods: A community based cross sectional study was done on 225 study subjects, using systemic random sampling method at Kancheepuram district, Tamil Nadu. Results: The study included 225 participants of which 53% were male and 47% were female. The overall prevalence of hypertension among the study population was 26.2%. Risk among male was greater than female (OR=1.390). Factors like age, body mass index, diet, family history of hypertension had significant association (p<0.05) with hypertension. Conclusions: Regular screening for hypertension among adults should be done in the general OPD as well as in health camps so that they have a knowledge regarding their own blood pressure status. Among those who already have hypertension, anti -hypertensive drugs, timely blood pressure check-up, screening for cardio vascular diseases and self-care management of hypertension need to be promoted. 


Author(s):  
Cristina Alvarez-Peregrina ◽  
Clara Martinez-Perez ◽  
Cesar Villa-Collar ◽  
Cristina Andreu-Vázquez ◽  
Alicia Ruiz-Pomeda ◽  
...  

Background: Myopia is a public health problem, with estimations that 50% of the world population will be myopic by 2050. Some environmental factors, such as time spent outdoors, doing near work, and using digital devices, influence the development of myopia in children. Home confinement in Spain has increased these risk factors, so this study aims to investigate the impact of home confinement during the COVID-19 outbreak in the vision of school-aged children; Methods: A cross-sectional study in children between 5 and 7 years old that completed a visual screening and a questionnaire about their lifestyles at opticians in Spain in September and October of 2019 and 2020. Statistical analysis to compare lifestyles pre and post confinement, and vision in 2020 versus a similar cohort examined at the same opticians in 2019, was conducted; Results: Spanish children spent less time outdoors and more time doing near work in 2020 than in 2019 (p ≤ 0.001). There was a significant decrease of the spherical equivalent (mean ± standard deviation; 0.66 ± 2.03 D in 2019 vs. 0.48 ± 1.81 D in 2020; p ≤ 0.001); Conclusions: Lifestyles of Spanish children changed during the home confinement at the beginning of 2020. Together with changes in their lifestyles, spherical equivalents have decreased, which implies higher figures of myopia for children aged between 5 and 7.


2021 ◽  
pp. 088626052110051
Author(s):  
Claudia L. de Moraes ◽  
Érika B. dos Santos ◽  
Michael E. Reichenheim ◽  
Stella R. Taquette ◽  
Luciane Stochero ◽  
...  

Community violence (CV) is a global public health problem due to its high frequency and severe consequences. Although CV is one of the leading causes of death among adolescents, little is known about the everyday CV situations that do not lead to death. This study aimed to estimate the frequency of exposure to and involvement in CV situations among adolescent students from public and private schools in the city of Rio de Janeiro, Brazil. This was a cross-sectional study of 693 individuals in their second year of high school selected through stratified multistage random sampling. Information about their exposure to and involvement in CV was collected through a self-completed multidimensional questionnaire in the classrooms. For approximately 30% of the adolescents, someone close to them had been murdered, and 40% had already seen the corpse of a victim of homicide. Seventeen percent reported having been directly involved in CV situations. Approximately 38%, 13%, and 25% had been victims of robberies, interpersonal aggression, and death threats to either themselves or their relatives, respectively. Many of these situations occurred more than once. In general, CV was more frequently reported by boys and by those who did not live with both parents. Adolescents from higher economic classes experienced more interpersonal aggression and felt a greater need to carry a gun. Those who belonged to the lower economic classes and studied in public schools were more exposed to lethal violence than other students. The results call attention to the very high percentage of adolescent students that are involved in CV situations as well as to the differences in violence rates among population subgroups. Such findings should be considered when planning CV prevention and management actions in schools and other socialization spaces for adolescents.


Author(s):  
Desirée Mena-Tudela ◽  
Susana Iglesias-Casás ◽  
Víctor Manuel González-Chordá ◽  
María Jesús Valero-Chillerón ◽  
Laura Andreu-Pejó ◽  
...  

Background: Obstetric violence is a worldwide public health problem, which seems greater in Spain. As no studies were found that identify the most representative healthcare professionals, times, and areas involved in obstetric violence, the objective of this work was to study at what time of maternity, with which professionals, and in what areas women identified obstetric violence. Methods: This descriptive, retrospective, and cross-sectional study was performed from January 2018 to June 2019. The main variables were the area (hospital, primary care, both), the time (pregnancy, birth, puerperium), and the professionals attending to women. Results: Our sample comprised 17,541 participants. The area identified with the most obstetric violence for the different studied variables was hospitals. Women identified more obstetric violence at time of birth. Findings such as lack of information and informed consent (74.2%), and criticism of infantile behavior and treatment (87.6%), stood out. The main identified healthcare professionals were midwives and gynecologists, and “other” professionals repeatedly appeared. Conclusions: Having identified the professionals, times, and areas of most obstetric violence in Spain, it seems necessary to reflect on not only the Spanish National Health System’s structure and management but also on healthcare professionals’ training.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tesfaldet Mekonnen Estifanos ◽  
Chen Hui ◽  
Afewerki Weldezgi Tesfai ◽  
Mekonnen Estifanos Teklu ◽  
Matiwos Araya Ghebrehiwet ◽  
...  

Abstract Background Youth in general and young females, in particular, remain at the center of HIV/AIDS epidemic. To avoid and prevent HIV infection, comprehensive knowledge as well as correct understanding of transmission and prevention strategies are crucial. Thus, the aim of this study is to explore the predictors of comprehensive knowledge on HIV/AIDS and accepting attitude towards PLWHIV. Methods A cross-sectional study was conducted using data from the 2016 Uganda Demographic Health Survey. A two-stage probability sampling method was applied and data were collected using a standard questionnaire. Of the total 8674 women aged 15–49 years, 1971 eligible women aged 15–24 years were included in this analysis. Data analysis was done using SPSS version 23. A Chi-square test followed by logistic regression analysis was used to explore the relationship between specific explanatory variables and outcome variables. The results were reported using odds ratios with 95% confidence interval. P value less than 0.05 was considered as statistically significant. Results Overall, 99.3% of the unmarried women aged 15–24 years were aware of HIV/AIDS, but only 51.9% had comprehensive knowledge on HIV/AIDS. Around 70% of the respondents were aware that "using condoms every time when having sex" and "having only one faithful uninfected partner" can prevent HIV transmission. About 68% of the unmarried women rejected at least two common local misconceptions about HIV/AIDS. An alarmingly small (20.6%) proportion of the respondents had a positive acceptance attitude towards PLWHIV. All variables were significantly associated with having comprehensive knowledge on HIV/AIDS in the unadjusted logistic regression analysis. After adjustment, older age (20–24 years), being educated, wealthier, and ever been tested for HIV/AIDS became predictors of adequate comprehensive HIV/AIDS knowledge. Moreover, respondents with adequate comprehensive knowledge of HIV/AIDS were more likely (OR 1.64, 95% CI 1.30–2.08) to have a positive acceptance attitude towards PLWHIV than their counterparts. Conclusion Our study demonstrated a remarkably high level of awareness about HIV/AIDS among study participants, but the knowledge and positive acceptance attitude towards PLWHIV were not encouraging. Thus, endeavors to expand and strengthen educational campaigns on HIV/AIDS in communities, health facilities, and schools are highly recommended. Attention should particularly focus on young-aged and disadvantaged women with low educational level, poor socioeconomic status and those who have never been tested for HIV/AIDS.


Author(s):  
Chutima Rattanawan ◽  
Suraiya Cheloh ◽  
Asma Maimahad ◽  
Malatee Tayeh

Anemia is a global public health problem. The prevalence of anemia among different ages, genders or ethnic groups must be clarified in order to solve problems. This study proposed to determine the prevalence and factors related to anemia among the Muslim school-age population in Nakhon Si Thammarat, Thailand. Socio-demographic and anthropometric data were collected by a structured questionnaire. Blood samples were collected from 200 school-age subjects. The thalassemia screening was performed with KKU-OF and KKU-DCIP reagents. The prevalence of anemia in this study was 36.5%, divided into males and females, 33.3% and 39.1%, respectively. The means of Hb, Hct, MCV, MCH, and MCHC in the anemic group were significantly lower. The positive results for KKU-OF or KKU-DCIP or both were 15.0%, 2.5%, and 1.0%, respectively. The result of positive OF test was a significantly independent factor for anemia. The number of family members was 5 to 7 and more than 7 persons are related factors for anemia in this study. In summary, the contribution of thalassemia and socio-economic factor are associated factors to anemia in this population. These findings should be addressed in public health strategies for the control of anemia of school-aged Muslims in the region.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mariam Mohsen Aly ◽  
Marwa Aly Elchaghaby

Abstract Background The use of antibiotics in dentistry as prophylaxis and treatment is frequent. Their misuse has led to a major public health problem globally known as antibiotic resistance. This study aimed to assess the pattern of antibiotic prescription and its prophylactic use for systemic conditions. Besides, this study evaluated the awareness and adherence to antibiotic prescription guidelines and antibiotic prophylaxis guidelines along with awareness of antibiotic resistance across pediatric and general dentists. Methods An overall of 378 pediatric and general dentists meeting the required eligibility criteria, fulfilled a pre-designed validated questionnaire. Data were collected, tabulated, and statistically analyzed. Results A significant statistical difference was found among the pediatric and general dentists regarding antibiotics prescription for most of the oral conditions where Amoxicillin with clavulanic acid was the most frequently prescribed antibiotic among the two groups (53% pediatric dentist and 52% general dentist). The majority of pediatric and general dentists, on the other hand, were aware of antibiotic resistance and prescribing recommendations. Conclusions The present study showed a tendency to overprescribe and overuse antibiotics in certain dental conditions among the participants. The vast majority of dentists, especially general dentists do not have adherence to professional guidelines for antibiotics prescription in children despite their awareness of antibiotic resistance and prescription guidelines.


Sign in / Sign up

Export Citation Format

Share Document