scholarly journals A study on adverse events following ChAdOx1 nCoV-19 CovishieldTM vaccination among beneficiaries at tertiary care centre, Hyderabad, India

2021 ◽  
Vol 8 (11) ◽  
pp. 5389
Author(s):  
Sunil Pal Singh Chajhlana ◽  
Anjaiah Kanusali ◽  
Guru Prasad Manderwad ◽  
Vineesh Allenki ◽  
Shashidhar Kamineni
Keyword(s):  
Side Effects ◽  
Adverse Events ◽  
Tertiary Care ◽  
Vaccine Uptake ◽  
Vaccine Hesitancy ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Independent Evidence ◽  
Validated Questionnaire

Background: COVID-19 vaccine in present pandemic situation has been emerged as a blessing in disguise. Studies found to be associated with vaccine side-effects and it is an important factor that influences the confidence of vaccine uptake in general population. Present study was designed to provide an independent evidence on ChAdOx1 nCoV-19 vaccine side effects.Methods: A cross sectional study was conducted between January 2021 and February 2021 at our tertiary care centre among health care workers vaccinated using a validated questionnaire. Study subjects were contacted through phone to know about any adverse events following immunization for 0-24 hours, 24-48 hours and 48-72 hours. Data collected was entered and analysed with MS excel software 2007 and Epi info 3.5.3.Results: Healthcare workers participated were 1364. Majority of the symptoms following immunization were highest in age group of 18-28 years. Reported symptoms were pain at the site of injection- 619 (45.4%), fever- 423 (31%), Body pains- 318 (23.3%), headache- 189 (13.9%), tiredness- 142 (10.4%), swelling at the site of injection- 40 (2.9%), dizziness- 30 (2.2%), redness at the site of injection- 25 (1.8%), joint pains- 23 (1.7%), rash- 06 (0.4%), Breathlessness- 03 (0.2%) respectively.Conclusions: Overall results found the occurrence of side-effects which are in terms of manufacturer’s data and it has been noticed in young age. This study imparts the confidence for taking vaccination and further studies are required to minimize vaccine hesitancy (VH) and strengthen the public to boost their confidence in present vaccination drive.

scholarly journals Adverse events following immunization: orchestrated outcome of mothers' knowledge and behavior on vaccination practices

2021 ◽  
Vol 8 (2) ◽  
pp. 802
Author(s):  
Neel M. Mishra ◽  
Sandeep Dhingra ◽  
K. M. Adhikari
Keyword(s):  
Side Effects ◽  
Adverse Events ◽  
Tertiary Care ◽  
Vaccine Hesitancy ◽  
Western India ◽  
Care Hospital ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Attitudes And Practices ◽  
Validated Questionnaire

Background: Adverse events following immunization (AEFI) are a common occurrence in children after vaccination and can lead to loss of trust in the immunization program. Fear of AEFIs is a major factor implicated in ‘Vaccine Hesitancy’ as seen in countries with high vaccination coverage and low burden of vaccine preventable diseases. The study aimed at assessing the knowledge, attitudes and practices of mothers regarding AEFI and its impact on vaccination of their childrenMethods: A descriptive, cross sectional survey was conducted at the immunization clinic of a tertiary care hospital of western India. Mothers attending the immunization clinic were interviewed using a validated questionnaire. A sample size of 221 was derived based on the incidence of common AEFIs.Results: Awareness of AEFI was present in 86.4% participants while only 28% mothers confirmed that information regarding AEFIs was given to them at the time of immunization. Though awareness of minor side effects like fever (98%) and local reaction (85%) was good, less than 15% of the mothers were aware of serious AEFIs such as seizures and anaphylaxis. Only 66% mothers indicated that they would first consult their doctor in case of an adverse effect. Knowledge regarding true contraindications to vaccination was poor.Conclusions: Awareness of the possibility of AEFI was good and trust in immunization as a vital health intervention was intact. Awareness about serious AEFIs which necessitate prompt management was inadequate while that for minor side effects was satisfactory. Healthcare seeking behavior of mothers to serious AEFIs was appropriate.

scholarly journals Towards more patient-centred endometriosis care: a cross-sectional survey using the ENDOCARE questionnaire

2020 ◽  
Vol 2020 (3) ◽  
Author(s):  
A M F Schreurs ◽  
M van Hoefen Wijsard ◽  
E A F Dancet ◽  
S Apers ◽  
W K H Kuchenbecker ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Diagnostic Delay ◽  
Care Centre ◽  
Cross Sectional Survey ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Tertiary Centre ◽  
Validated Questionnaire ◽  
Physical Comfort ◽  
Patient Centredness

Abstract STUDY QUESTION What is the performance of the patient-centredness of endometriosis care in a secondary and a tertiary care setting and how can it be improved? SUMMARY ANSWER Overall, patient-centredness was comparable in the two endometriosis care centres, but differed regarding ‘physical comfort’ and ‘continuity and transition’; both centres can learn how to improve several of their targets from the other’s strengths. WHAT IS KNOWN ALREADY The ENDOCARE questionnaire (ECQ) is a validated questionnaire for assessing the important quality dimension ‘patient-centredness’. Patient-centredness is associated with quality of life, although this should be explored further by larger-scale studies. STUDY DESIGN, SIZE, DURATION A cross-sectional survey, relying on the ECQ, was performed (during 2015 and 2016) among 407 women with surgically diagnosed endometriosis. PARTICIPANTS/MATERIALS, SETTING, METHODS This study was conducted in a secondary and a tertiary care centre in the Netherlands. A total of 209 Dutch-speaking women who had endometriosis surgery (2013–2014), completed the ECQ after a postal invitation and, if needed, postal reminders. The assessed outcomes were: overall patient-centredness, the patient-centredness for each of its 10 dimensions, and the patient-centred strengths and targets for improvement. Case-mix adjusted patient-centredness scores (PCS) were compared and strengths and targets for improvement were identified with a matrix modelling importance against experience. The need to improve the targets was quantified with quality impact indices. MAIN RESULTS AND THE ROLE OF CHANCE No difference was demonstrated between the overall PCS of the secondary and tertiary centres (respectively: 4.8 and 4.5; P = 0.15). No difference was found in PCS per dimension between the two clinics except for the secondary care centre performing better regarding ‘physical comfort’ (respectively: 4.5 and 3.0; P = 0.01) and ‘continuity and transition’ (respectively: 6.0 and 4.2; P = 0.01). The two centres had nine targets for improvement in common. The secondary and tertiary centres, respectively, had five and seven additional centre-specific targets for improvement. Cross-centre learning is encouraged as 9 out the 12 additional centre-specific targets were strengths in the other centre. The main improvement targets were being able to contact the centre in case of emergency (both centres), the involvement of a significant other (secondary centre), diagnostic delay (secondary centre), personal follow-up (tertiary centre) and disclosing the level of competence of healthcare providers (tertiary centre). LIMITATIONS, REASON FOR CAUTION Responders did not differ from non-responders in their stage of endometriosis, educational level, rating of endometriosis care and degree to which their complaints are suppressed. Endometriosis is a chronic condition and patient-centredness might be experienced differently at other points of the endometriosis care trajectory. WIDER IMPLICATION OF THE FINDINGS The ECQ is a useful tool to assess patient-centredness in both secondary and tertiary care centres. Further research should focus on how to improve endometriosis care. STUDY FUNDING/COMPETING INTEREST(S) No external funding was used. V.M. and C.B.L. report grants from Guerbet, grants from Merck and grants from Ferring outside the submitted work. All authors declare that they have no competing interests concerning this publication.

scholarly journals Awareness, perceptions and dental services utilization by patients a tertiary care centre during COVID-19 pandemic

2020 ◽  
pp. 634-643
Keyword(s):  
Tertiary Care ◽  
Control Measures ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Dental Services ◽  
Cross Sectional ◽  
Services Utilization ◽  
Preventive Practices ◽  
Validated Questionnaire ◽  
Dental Services Utilization

BACKGROUND. COVID -19 pandemic has imposed multiple questions and consideration in the minds of the patients and dental professionals. The understanding of patient’s perceptions and dental services utilization can aid in modifying the pre-existing dental practices. The aim of the present study was to assess the awareness, perceptions and dental services utilization by patients visiting a tertiary care centre during COVID-19. METHODOLOGY. A cross-sectional study on 437 patients was carried using a validated questionnaire consisting of 22 questions on three domains. Strict sterilization protocol and infection control measures were practiced to avoid any contact between the investigator and the patient. RESULTS. Patients were aware of COVID -19 pandemic and were willing (76.7%) to inculcate preventive practices even post-pandemic. Concerns regarding the spread of infection (37.3%) and hygiene/cleanliness (28.6%) were most commonly reported. Patients visited the dental centre primarily for emergency management and preferred their queries being solved on the phone. CONCLUSION. Patients had a positive outlook towards visiting the dental centre for treatment in the near future and did not report any anxiety before visiting a dental centre.

scholarly journals Adenovirus and RNA-based COVID-19 vaccines’ perceptions and acceptance among healthcare workers in Saudi Arabia: a national survey

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e048586
Author(s):  
Mohamad-Hani Temsah ◽  
Mazin Barry ◽  
Fadi Aljamaan ◽  
Abdullah Alhuzaimi ◽  
Ayman Al-Eyadhy ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Healthcare Workers ◽  
Online Survey ◽  
Healthcare Providers ◽  
Vaccine Uptake ◽  
Vaccine Hesitancy ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
Vectored Vaccine ◽  
To Receive

ObjectivesThe aim of this study was to compare the perception, confidence, hesitancy and acceptance rate of various COVID-19 vaccine types among healthcare workers (HCWs) in Saudi Arabia, a nation with Middle East respiratory syndrome coronavirus experience.DesignNational cross-sectional, pilot-validated questionnaire.SettingOnline, self-administered questionnaire among HCWs.ParticipantsA total of 2007 HCWs working in the Kingdom of Saudi Arabia participated; 1512 (75.3%) participants completed the survey and were included in the analysis.InterventionData were collected through an online survey sent to HCWs during 1–15 November 2020. The main outcome measure was HCW acceptance of COVID-19 candidate vaccines. The associated factors of vaccination acceptance were identified through a logistic regression analysis and via measurement of the level of anxiety, using the Generalised Anxiety Disorder 7 scale.ResultsAmong the 1512 HCWs who were included, 62.4% were women, 70.3% were between 21 and 40 years of age, and the majority (62.2%) were from tertiary hospitals. In addition, 59.5% reported knowing about at least one vaccine; 24.4% of the participants were sure about their willingness to receive the ChAdOx1 nCoV-19 vaccine, and 20.9% were willing to receive the RNA BNT162b2 vaccine. However, 18.3% reported that they would refuse to receive the Ad5-vectored vaccine, and 17.9% would refuse the Gam-COVID-Vac vaccine. Factors that influenced the differential readiness of HCWs included their perceptions of the vaccine’s efficiency in preventing the infection (33%), their personal preferences (29%) and the vaccine’s manufacturing country (28.6%).ConclusionsAwareness by HCWs of the several COVID-19 candidate vaccines could improve their perceptions and acceptance of vaccination. Reliable sources on vaccine efficiency could improve vaccine uptake, so healthcare authorities should use reliable information to decrease vaccine hesitancy among frontline healthcare providers.

scholarly journals Assessment of knowledge, attitudes and practice among the post graduate students of dentistry and physiotherapy towards adverse drug reactions reporting and pharmacovigilance at a tertiary care centre at Indore, India

2018 ◽  
Vol 7 (4) ◽  
pp. 626
Author(s):  
Gopal Gudsurkar ◽  
Vikalp Tiwari ◽  
Pooja Solanki Mishra
Keyword(s):  
Graduate Students ◽  
Graduate Student ◽  
Single Point ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Post Graduate ◽  
Adr Reporting ◽  
Post Graduate Student

Background: Pharmacovigilance knowledge and training in post graduate student doctors is key factor for proper implementation of PvPI. Often the dentists and physiotherapists who are also one of the main stakeholders for ADR reporting are neglected for training and knowledge regarding pharmacovigilance. This study was planned to evaluate the knowledge and awareness of pharmacovigilance in post graduate students in tertiary care centre in Indore.Methods: It was a single point cross sectional questionnaire-based study conducted in a tertiary care Institute MGM Medical College and M.Y. Hospital in the state of Madhya Pradesh at Indore. It was conducted among post graduate student doctors from dentistry and physiotherapy. Total of 55 questionnaires were distributed, 50 of them were returned back and were analysed.Results: Overall knowledge level was average. 90% knew about ADR while 80% were aware about PVPI. 10% knew about local AMC at Indore while only 04% knew global centre for Pharmacovigilance is at Sweden Uppsala. 88% thought Med watch as global database for ADR against only 12% knew its Vigibase. 90% thought ADR reporting is necessary. 96% thought it should be included in UG curriculum. 98% had not reported any ADR till date while 84% had not seen an ADR form.Conclusions: Post graduate doctors are the prime candidates to impart the importance of pharmacovigilance. The study strongly suggested that there was a great need to create awareness and impart training among the post graduate doctors to improve the reporting of ADRs.

scholarly journals Case reports on erosive pustular dermatosis of scalp: a cross sectional study at a tertiary care centre

2020 ◽  
Vol 6 (2) ◽  
pp. 260
Author(s):  
Avanitaben D. Solanki ◽  
Neha S. Nagrani ◽  
Dhara V. Patel ◽  
Neela M. Patel ◽  
Jigna P. Barot ◽  
...  
Keyword(s):  
Case Reports ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Neutrophilic Dermatosis ◽  
Repeated Treatment ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Proper Diagnosis ◽  
Folliculitis Decalvans

<p class="abstract">Erosive pustular dermatosis of the scalp (EPDS) has been reported as a rare chronic and progressive non-infectious inflammatory condition of the actinically damaged scalp characterized by crusts, erosions and pustules. It tends to occur on the scalp of older people who have usually been treated for diffuse actinic damage and actinic keratoses. The list of possible differential diagnosis is long and includes tinea capitis, folliculitis decalvans, neutrophilic dermatosis, autoimmune vesiculobullous disorders, malignancy etc. Notoriously difficult to treat, these cases tend to be chronic and progressive. These patients often present after repeated treatment to various scalp dermatosis that doesn’t result in clearing instead persistence and perpetuation of the process. A cross sectional prospective study was conducted in department of dermatology in a tertiary care centre in which six cases of EPDS attending outpatient department from 2017 to 2019 were included. EPDS is more common but under recognized condition, hence less cases are reported till date. Increased awareness of and proper diagnosis of this condition changes the approach towards these patients, protects the scalp from involuntary insults and other precipitating factors that hinders with a better outcome.</p>

CLINICOEPIDEMIOLOGICAL STUDY OF CHILDHOOD PSORIASIS PATIENTS AND ITS ASSOCIATION WITH HLA-CW6 IN A TERTIARY CARE CENTRE OF EASTERN INDIA

2021 ◽  
pp. 10-11
Author(s):  
Akhilesh Behra
Keyword(s):  
Tertiary Care ◽  
Epidemiological Data ◽  
Clinical History ◽  
Cross Sectional Study ◽  
Care Centre ◽  
Eastern India ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Plaque Type ◽  
Worldwide Population

BACKGROUND- Psoriasis is chronic common papulosquamous disorder. Its aetiology included various environmental and genetic factors. In genetics, HLA-Cw6 is most commonly associated with psoriasis. Childhood psoriasis is also common in worldwide population. However, very few studies done on epidemiological data and HLA-Cw6 analysis in childhood psoriasis patients. AIMS AND OBJECTIVE- Clinicoepidemiological study of childhood psoriasis patients and its association with HLA-Cw6 in a tertiary care centre of Eastern India MATERIALAND METHOD- We conducted a cross-sectional study in a tertiary care centre and recruited 20 patients of psoriasis with age group below 18 years after taking proper consent. Clinical history and blood was taken from them and HLA-Cw6 analysis was done by PCR method. Data compilation was done by Microsoft excel using SPSS software. RESULTS- A total of the 20 childhood psoriasis patients, 9 were males and 11 were females. Generalized plaque type psoriasis (N=19) is commonest followed by guttate psoriasis (N=1). None of the patients had arthalgia. Family history was present in only 3 patients. Higher numbers of childhood psoriasis patients (N=14) were positive for HLA-Cw6. Also Higher numbers of females (N=10) were positive for HLA-Cw6. ve patients had nail changes. CONCLUSION- We found HLA-Cw6 is strongly associated with childhood psoriasis and also HLA-Cw6 frequency is higher in female than male childhood psoriasis patients.

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