scholarly journals Cutaneous manifestations in obese patients and non-obese controls in a tertiary care centre: a case-control study

2019 ◽  
Vol 5 (4) ◽  
pp. 695
Author(s):  
Raghuveer Chekuri ◽  
Thameena Mohamed
Keyword(s):  
Acanthosis Nigricans ◽  
Tertiary Care ◽  
Control Group ◽  
Obese Patients ◽  
Striae Distensae ◽  
Tertiary Care Centre ◽  
Cutaneous Manifestations ◽  
High Prevalence ◽  
Skin Conditions ◽  
And Function

<p class="abstract"><strong>Background:</strong> Obesity has emerged as one of the most serious public health concerns in the 21<sup>st</sup> century. It is responsible for varied changes in structure and function of different components of skin. Skin care of obese patients deserves particular attention, not only because of high prevalence of cutaneous alteration but mainly because many of these disorders are preventable and could be treated, improving patient’s quality of life.</p><p class="abstract"><strong>Methods:</strong> Two hundred patients with BMI ≥30 kg/m<sup>2</sup> and two hundred age and sex matched controls (BMI: 18.5-24.9 kg/m<sup>2</sup>) were included in this study.<strong></strong></p><p class="abstract"><strong>Results:</strong> Compared to the control group, obese patients were having higher prevalence of various skin conditions of which most common were acanthosis nigricans, acrochordons, striae distensae, frictional hyperpigmentation and infections.</p><p class="abstract"><strong>Conclusions:</strong> There is increased incidence and severity of cutaneous manifestations like acanthosis nigricans, acrochordons, striae distensae, frictional hyperpigmentation and infections in obese patients than control subjects. These can be used as markers for the early detection of various components of metabolic syndrome.</p>

scholarly journals Various presentations of cutaneous tuberculosis at a tertiary care centre: a one year prospective study

2018 ◽  
Vol 4 (4) ◽  
pp. 559
Author(s):  
N. S. Jayanthi ◽  
V. Anandan ◽  
S. Kopika
Keyword(s):  
Prospective Study ◽  
Tertiary Care ◽  
Tertiary Care Centre ◽  
Cutaneous Manifestations ◽  
Cutaneous Tuberculosis ◽  
Pulmonary Manifestations ◽  
High Prevalence ◽  
Rare Manifestation ◽  
One Year ◽  
High Index Of Suspicion

<p class="abstract"><strong>Background:</strong> Cutaneous tuberculosis is a rare manifestation of tuberculosis accounting for about 1.5% of all the extra pulmonary manifestations, though the prevalence of pulmonary tuberculosis is high in India. The aim of the study was to prospectively analyze the various clinical presentations of cutaneous TB and their age and sex distribution among the OPD attending patients over a period of one year.</p><p class="abstract"><strong>Methods:</strong> Prospective study, conducted during July 2016 to June 2017. Clinically suspected cases of cutaneous tuberculosis were subjected to lesional biopsy and the results obtained were analyzed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 36 clinically suspected cases, 24 turned out to be cutaneous tuberculosis and apart from these, 5 cases were referred from other departments as cutaneous tuberculosis. The predominant presentation was lupus vulgaris in 12 patients, followed by tuberculous verrucosa cutis in 8 cases, tuberculous ulcers in 3 cases and the remaining 2 cases were erythema induratum of Bazin. Among them, 13 were men accounting to about 52% and 7 were children which accounted for 28% and the remaining 5 were women which added to 20%.</p><p class="abstract"><strong>Conclusions:</strong> Though the cutaneous manifestations of tuberculosis is very rare, the recent years have shown a rising incidence especially among children and therefore requires a high index of suspicion in them since India has very high prevalence of tuberculosis as such.</p>

Study of Clinical Profile Associated with Obesity amongst Dermatology Patients In A Tertiary Care Centre

2020 ◽  
Vol 7 (4) ◽  
pp. 97-103
Author(s):  
Dr. Nausheen Syed ◽  
Dr. Supriya R. Vikhe Patil ◽  
Dr. Nilesh Rafaliya ◽  
Dr. Ramesh Gosavi
Keyword(s):  
Primary Care Physicians ◽  
Bacterial Infections ◽  
Acanthosis Nigricans ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Striae Distensae ◽  
Tertiary Care Centre ◽  
Skin Change ◽  
Adiposis Dolorosa ◽  
Skin Tag

Background: Obesity is a global epidemic. Obesity is associated with a number of dermatoses, including acanthosis nigricans, skin tag, keratosis pilaris, hyperandrogenism and hirsutism, striae distensae, and adiposis dolorosa. Objective: To elucidate the various skin changes in obesity and to determine if it is considered as an obesity marker. Methodology: 100 patients, aged 18 years or above satisfying the inclusion and exclusion criteria were drawn for a period of 18 months. Results: Out of 100 patients 54% were female, in their third and fourth decade. By occupation most of the females were housewives (40%) and the majority of males were farmers (14%). Type 2 diabetes mellitus was the most common systemic illness (24%). Pseudoacanthosis nigricans was the most prevalent skin change. 51% of patients had skin tags. 48% had striae distensae as a skin change. 10.86% male and 14.81% female patients had stasis dermatitis, 6% had leg venulectasias and 2% had leg ulcer. 26% had plantar hyperkeratosis. 41% of our patients had one or other types of fungal infections. Bacterial infections were detected in 15% cases, folliculitis being the commonest. Conclusion: Obesity is strongly related to several skin alterations that could be considered as markers of excessive weight. The dermatoses that showed a statistically significant relationship with obesity were Pseudo acanthosis nigricans, Skin tag, Striae, Plantar hyperkeratosis and Fungal infections. Prevention of obesity is important to prevent these dermatoses and dermatologists must work with primary care physicians and patients to reduce the harmful effects of obesity on the skin.

scholarly journals Study of cutaneous manifestations in patients with polycystic ovarian syndrome attending a tertiary care centre

2019 ◽  
Vol 5 (3) ◽  
pp. 481
Author(s):  
Chinmai Yerram ◽  
Garimella Venkateswara Rao ◽  
Krishna Rajesh Kilaru
Keyword(s):  
Acanthosis Nigricans ◽  
Polycystic Ovary ◽  
Acne Vulgaris ◽  
Tertiary Care ◽  
Positive Family History ◽  
Age Groups ◽  
Tertiary Care Centre ◽  
Cutaneous Manifestations ◽  
Medical College ◽  
History Of

<p class="abstract"><strong>Background:</strong> Polycystic ovary syndrome (PCOS) is a multisystem metabolic disorder, which has a significant impact on the quality of life as well as fertility.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372429/#ref1"><sup>1</sup></a><sup>,</sup><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372429/#ref2"><sup>2</sup></a> Acne, hirsutism, androgenetic alopecia, acanthosis nigricans, seborrhea are commonly associated with cutaneous manifestations of PCOS. To identify cutaneous manifestations, their incidence and frequency in patients with PCOS in different age groups.</p><p class="abstract"><strong>Methods:</strong> An institutional based prospective study. <em>Seventy PCOS patients attending out-patient departments of DVL and Obstetrics and Gynaecology, NRI Medical College and General Hospital, Guntur, </em>fulfilling the inclusion criteria were included in the study and examined for the presence of cutaneous manifestations in the two year study period between January 2017 and December 2018.<strong></strong></p><p class="abstract"><strong>Results:</strong> In the present study, 70 patients with PCOS were taken up and the commonest age group affected was 21-25 years (42.8%). Positive family history of PCOS was observed in 12.8%. The commonest cutaneous manifestation was acne vulgaris (57.14 %). Obesity was present in 47.14% of the patients and all of them were found to have striae. Hirsutism was observed in 47.14% of the total patients studied and the majority of them had terminal hair in the chin region and upper lip. Acanthosis nigricans was present in 34.28%, seborrhoea in 21.42% and acrochordons in 17.14% of the patients. Of the 70 patients, 15.7% were overweight and 47.14% were obesity.</p><p class="abstract"><strong>Conclusions:</strong> The cutaneous manifestations of PCOS reserves major role in its management by Dermatologist. Recognizing PCOS in women presenting with hyperandrogenism offers a significant opportunity to begin a life-long conversation about prevention and treatment of a condition that has a multi-system impact on affected women.</p>

Carnitine deficiency in chronic obstructive lung disease: A study in a tertiary care centre

2021 ◽  
Vol 6 (3) ◽  
pp. 183-187
Author(s):  
M Ravindranath ◽  
C H Raju
Keyword(s):  
Lung Disease ◽  
Obstructive Lung Disease ◽  
Tertiary Care ◽  
Chronic Obstructive Lung Disease ◽  
Carnitine Deficiency ◽  
Control Group ◽  
Chronic Obstructive ◽  
X Rays ◽  
Tertiary Care Centre ◽  
Regular Diet

Chronic Obstructive Lung Disease (COPD) is a condition where there is poor airflow to the lungs and over a period of time this condition worsen, resulting in severe morbidity. L-carnitine (LC) is a soluble qaurtenary amine and is essential for the tissues and lung tone to function normally. This study was therefore find out the association of L-carnitine in patients with chronic Obstructive Pulmonary Disease. 75 patients who came to the Department of Pulmonology of either sex between 40 to 75 years with confirmed COPD were included into patients group and 75 healthy patients were included into the control group. Blood was collected for Fasting blood sugar, AST, ALP, ALT, Urea, Creatinine, Albumin, pre-albumin, iron , magnesium, sodium, phosphorous, calcium, Acylcarnitines, total and free carnitine levels. X-rays were taken and pulmonary function test was done for all the patients. The mean age of the patients in our study was 62.53 and 61.86 years among the patients and controls respectively. Among the controls the Ph and Fe levels were 3.1 ± 0.9mmol/L and 21.69 ± 3.19 mcg/dL respectively and among the patients the same levels were 2.6 ± 1.9mmol/L and 43.82 ± 8.22mcg/dL respectively. The albumin and the prealbumin in the patients were significantly lower in the patients with 21.81 ± 2.88 and 23.53 ±2.58 mg/dL and in controls they were 32.61 ±3.87 and 26.87 ± 1.93 mg/dL respectively. There was a considerable carnitine deficiencies in COPD patients when compared to the controls and since carnitine can be found in regular diet, people can be educated to have a proper intake of foods containing carnitine in their regular diet.

scholarly journals Evaluation of therapeutic effectiveness of vitamin D3 injections in common warts in a tertiary care centre

2019 ◽  
Vol 5 (3) ◽  
pp. 462
Author(s):  
Sushmalatha Banoth
Keyword(s):  
Vitamin D3 ◽  
Normal Saline ◽  
Tertiary Care ◽  
Treatment Session ◽  
Tertiary Care Centre ◽  
Cutaneous Manifestations ◽  
Multiple Modalities ◽  
Common Warts ◽  
Group A ◽  
Group B

<p class="abstract"><strong>Background:</strong> Warts or verrucae are the benign cutaneous manifestations caused by human papilloma virus. The treatment of wart possess a therapeutic challenge, as a result multiple modalities are existing for the treatment of cutaneous warts, which is cumbersome and may result in cosmetic disfigurement, chances of recurrences. The aim of the present study was to determine the resolution of common warts in response to vitamin D3 injections and to compare the resolution of common warts in the group receiving vitamin D3 with placebo group receiving normal saline.</p><p class="abstract"><strong>Methods:</strong> A total of 26 patients were enrolled and divided into Group A- received lesional injection of 0.2 ml vitamin D3 every 3 weeks for 3 months for the improvement in the size of warts. Group B- received 0.2 ml of normal saline injections as a control. The maximum of three sessions were carried in both groups. Clinical assessment was done by photographic evaluation at baseline, before each treatment session, and after completion of treatment.<strong></strong></p><p class="abstract"><strong>Results:</strong> In group A, 76.92% (10) of the patients showed complete clearance of wart with vitamin D3 injection, while in group B 8% (1) of patients with normal saline showed partial response. This therapy was well tolerated except for the minimal side effects like pain, redness and swelling at the site of injection.</p><p class="abstract"><strong>Conclusions:</strong> Intralesional Vit D3 injections may be a treatment option for warts, which has a good cosmetical acceptance and simple, well tolerated easily administrated in outpatient clinic rather than conventional treatment.</p>

CUTANEOUS MANIFESTATIONS OF HIV IN PEOPLE LIVING WITH HIV/AIDS AT TERTIARY CENTRE

2021 ◽  
pp. 70-72
Author(s):  
Anubhav Agrawal ◽  
Simmi Dube ◽  
Aditya Tejwani
Keyword(s):  
Cell Count ◽  
Tertiary Care ◽  
Skin Lesions ◽  
Cd4 Count ◽  
People Living With Hiv ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Cutaneous Manifestations ◽  
Cd4 Cell Count ◽  
Cd4 Cell

BACKGROUND-The study was conducted to describe systematic clinical manifestations among HIV in PLHA at tertiary care centre. METHODOLOGY- This study was designed as cross sectional study at Department of Medicine, tertiary care centre. A total of 100 HIV infected patients were included detailed enquiry about presence of skin lesions along with CD4 cell count was obtained and entered in pretested questionnaire RESULTS-The mean age of patients with HIV was 43.9±10.2 years and Slight female preponderance was observed with male: 3 female ratio of 0.89:1. Mean CD4 count was 243.2±103.2 cells/mm . Majority of patients had CD4 count in the range of less than 3 200 cells/mm (64%) Staphylococcal skin infections were the most common skin lesions observed in 34% patients. All the patients with cutaneous manifestations presented in present study had low CD4 cell count. However, no statistically signicant association between CD4 count and cutaneous manifestations could be documented (p>0.05). CONCLUSION-Cutaneous manifestations are more prevalent in patients with lower CD4 counts and can also be observed with normal CD4 count levels amongst patients with HIV. Occurrence of cutaneous manifestations was higher in patients with lower CD4 count but the observed difference was not statistically signicant.

CLINICAL PROFILE OF OUTPATIENTS ATTENDING DERMATOLOGY DEPARTMENT DURING COVID-19 LOCKDOWN RELAXATION PERIOD IN A TERTIARY CARE CENTRE IN SOUTH INDIA – A CROSS-SECTIONAL ANALYTICAL STUDY

2021 ◽  
pp. 13-16
Author(s):  
Afthab Jameela Wahab ◽  
Pavithra Gunasekaran ◽  
P. Mohan ◽  
V. Sudha ◽  
L. Balamurugan ◽  
...  
Keyword(s):  
South India ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Dermatology Department ◽  
Cutaneous Manifestations ◽  
Relaxation Period ◽  
Number Of Patients ◽  
Outpatient Practice ◽  
The Impact

Background - The cutaneous manifestations of the novel coronavirus have been well documented. However, there are few studies that relate to the clinical prole of regular dermatology outpatients seeking treatment during the lockdown relaxation period braving the pandemic. With the Aim - view to determine the changes seen in dermatology outpatient practice, this study analysed the clinical prole of new patients attending the Dermatology Outpatient Department (OPD) during the COVID-19 lockdown relaxation period in a tertiary care centre in a metropolitan suburb in South India. New dermatology outpatients during the months of May, June, July and August Method - 2020 were included in the study. Outpatient data for this period was analysed and compared with corresponding data for the same period in the previous two years. There was a Result – decrease in the OP census, number of patients in the extremes of life as well as those with asymptomatic dermatoses. There was an increase in the number of patients with infections, particularly dermatophytosis. There was also a noteworthy absence of dermatological emergencies. Conclusion - In essence, our study shows the impact of COVID-19 pandemic on the routine dermatology outpatient services with signicant changes in the clinical prole of outpatient practice following lockdown relaxation.

scholarly journals Epidural analgesia during labour: its influences on pain relief, progress of labour, mode of delivery, maternal and foetal

2020 ◽  
Vol 9 (2) ◽  
pp. 555
Author(s):  
M. Suneetha ◽  
A. Saritha
Keyword(s):  
Pain Relief ◽  
Epidural Analgesia ◽  
Tertiary Care ◽  
Mode Of Delivery ◽  
Obstetric Care ◽  
Fetal Outcome ◽  
Control Group ◽  
Sitting Position ◽  
Tertiary Care Centre ◽  
Group 2

Background: Today, the availability of regional anaesthesia for labour is considered a reflection of standard obstetric care. This study is to be conducted in a tertiary care centre with all facilities available for proposed end of proving that epidural analgesia is a safe and effective method for both parturient and the foetus in abolishing pain during labour.Methods: A total of 60 parturients were studied. they were randomly divided into two groups Group 1 includes 30 parturients. In this group parturient received epidural analgesia. The loading dose consisted of 10 ml of Bupivacaine 0.1% and Fentanyl 0.0002% (20 mcg). The top up doses were 10 ml of 0.1% Bupivacaine and Fentanyl 0.0002%, administered whenever the parturient complained of pain. When parturients enters into second stage a further 12-15 ml was injected with parturient in sitting position or semi-sitting position. Group 2 - (control group) Includes 30 parturients. In this group parturient was monitored without any analgesia.Results: This prospective study was done to assess the effect of epidural analgesia on the progress of labour and its outcome, to evaluate its efficacy as an analgesic technique and to study the maternal and fetal outcome. The total number of 60 parturients were selected and randomly categorized into two groups. CASE-Those who received epidural analgesia, CONTROL-Those who did not receive any analgesia.Conclusions: Epidural analgesia provides a versatile method of administering effective and satisfactory pain relief to parturient women. The technique should not be considered as a single entity, because the type and the dose of epidural medication can be altered as needed.

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