Study of Clinical Profile Associated with Obesity amongst Dermatology Patients In A Tertiary Care Centre

2020 ◽  
Vol 7 (4) ◽  
pp. 97-103
Author(s):  
Dr. Nausheen Syed ◽  
Dr. Supriya R. Vikhe Patil ◽  
Dr. Nilesh Rafaliya ◽  
Dr. Ramesh Gosavi
Keyword(s):  
Primary Care Physicians ◽  
Bacterial Infections ◽  
Acanthosis Nigricans ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Striae Distensae ◽  
Tertiary Care Centre ◽  
Skin Change ◽  
Adiposis Dolorosa ◽  
Skin Tag

Background: Obesity is a global epidemic. Obesity is associated with a number of dermatoses, including acanthosis nigricans, skin tag, keratosis pilaris, hyperandrogenism and hirsutism, striae distensae, and adiposis dolorosa. Objective: To elucidate the various skin changes in obesity and to determine if it is considered as an obesity marker. Methodology: 100 patients, aged 18 years or above satisfying the inclusion and exclusion criteria were drawn for a period of 18 months. Results: Out of 100 patients 54% were female, in their third and fourth decade. By occupation most of the females were housewives (40%) and the majority of males were farmers (14%). Type 2 diabetes mellitus was the most common systemic illness (24%). Pseudoacanthosis nigricans was the most prevalent skin change. 51% of patients had skin tags. 48% had striae distensae as a skin change. 10.86% male and 14.81% female patients had stasis dermatitis, 6% had leg venulectasias and 2% had leg ulcer. 26% had plantar hyperkeratosis. 41% of our patients had one or other types of fungal infections. Bacterial infections were detected in 15% cases, folliculitis being the commonest. Conclusion: Obesity is strongly related to several skin alterations that could be considered as markers of excessive weight. The dermatoses that showed a statistically significant relationship with obesity were Pseudo acanthosis nigricans, Skin tag, Striae, Plantar hyperkeratosis and Fungal infections. Prevention of obesity is important to prevent these dermatoses and dermatologists must work with primary care physicians and patients to reduce the harmful effects of obesity on the skin.

scholarly journals Cutaneous manifestations in obese patients and non-obese controls in a tertiary care centre: a case-control study

2019 ◽  
Vol 5 (4) ◽  
pp. 695
Author(s):  
Raghuveer Chekuri ◽  
Thameena Mohamed
Keyword(s):  
Acanthosis Nigricans ◽  
Tertiary Care ◽  
Control Group ◽  
Obese Patients ◽  
Striae Distensae ◽  
Tertiary Care Centre ◽  
Cutaneous Manifestations ◽  
High Prevalence ◽  
Skin Conditions ◽  
And Function

<p class="abstract"><strong>Background:</strong> Obesity has emerged as one of the most serious public health concerns in the 21<sup>st</sup> century. It is responsible for varied changes in structure and function of different components of skin. Skin care of obese patients deserves particular attention, not only because of high prevalence of cutaneous alteration but mainly because many of these disorders are preventable and could be treated, improving patient’s quality of life.</p><p class="abstract"><strong>Methods:</strong> Two hundred patients with BMI ≥30 kg/m<sup>2</sup> and two hundred age and sex matched controls (BMI: 18.5-24.9 kg/m<sup>2</sup>) were included in this study.<strong></strong></p><p class="abstract"><strong>Results:</strong> Compared to the control group, obese patients were having higher prevalence of various skin conditions of which most common were acanthosis nigricans, acrochordons, striae distensae, frictional hyperpigmentation and infections.</p><p class="abstract"><strong>Conclusions:</strong> There is increased incidence and severity of cutaneous manifestations like acanthosis nigricans, acrochordons, striae distensae, frictional hyperpigmentation and infections in obese patients than control subjects. These can be used as markers for the early detection of various components of metabolic syndrome.</p>

scholarly journals Cutaneous manifestations of diabetes mellitus: a clinical study

2018 ◽  
Vol 4 (3) ◽  
pp. 352
Author(s):  
Nancy Bhardwaj ◽  
Samarjit Roy ◽  
Rashmi Jindal ◽  
Sohaib Ahmad
Keyword(s):  
Diabetes Mellitus ◽  
Bacterial Infections ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Diabetic Control ◽  
Diabetic Patients ◽  
Tertiary Care Centre ◽  
Cutaneous Manifestations ◽  
Female Ratio ◽  
Cutaneous Infections

<p class="abstract"><strong>Background:</strong> Diabetes mellitus is a leading cause of morbidity with adverse effects on various systems including skin. Cutaneous manifestations seen in diabetes aid in its diagnosis and some of them may also correlate with diabetic control, duration and other complications. This study was undertaken to estimate burden of skin disorders among diabetics in a tertiary care centre of Uttarakhand.</p><p class="abstract"><strong>Methods:</strong> The study was conducted at Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India, over a period of one year from January 2016 to December 2016. Three hundred and seventy seven patients irrespective of age and sex were included in the study and those with gestational diabetes were excluded. Patients were examined for mucocutaneous manifestations and evaluated. Structured case reporting form was used to generate data.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 377 patients studies, 114 (30.2%) were in the age group of 51-60 years. Male to female ratio was 1.44:1. Mucocutaneous manifestations were present in 278/377 (73.7%) patients. Common cutaneous manifestations were cutaneous infections [fungal infections (n=106/377; 28.1%), bacterial infections (n=33/377; 8.8%)], pruritus (n=47/377; 12.5%), xerosis (n=39/377; 10.3%), diabetic dermopathy (n=36/377; 9.5%) and diabetic ulcers (n=24/377; 6.4%). Uncommon manifestations were necrobiosis lipoidica diabeticorum, alopecia areata, scleredema diabeticorum and granuloma annulare. Cutaneous reactions due to treatment of diabetes were noted in 4 (1%) patients.</p><p class="abstract"><strong>Conclusions:</strong> As prevalence of cutaneous manifestations is high in diabetic patients, knowledge of these will help in a timely and comprehensive management of both diabetes and dermatoses.</p>

scholarly journals A study of cutaneous manifestations in diabetes mellitus patients in tertiary care centre

2019 ◽  
Vol 5 (3) ◽  
pp. 571
Author(s):  
Kirankanth Vudayana ◽  
K. Sudheer ◽  
Dilipchandra Chintada
Keyword(s):  
Diabetes Mellitus ◽  
Bacterial Infections ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Tertiary Care Centre ◽  
Cutaneous Lesions ◽  
Cutaneous Manifestations ◽  
Cutaneous Infections ◽  
Patients With Diabetes ◽  
Medical Wards

<p class="abstract"><strong>Background:</strong> Diabetes is the most common metabolic disorder with increased prevalence in developing countries like India. It affects almost all organs among which skin is affected by the acute metabolic derangments as well as by chronic degenerative complications. The aims were to study the pattern of cutaneous lesions in patients with diabetes mellitus and to determine the incidence of skin manifestations specific to and associated with diabetics.</p><p class="abstract"><strong>Methods:</strong> Hundred cases of diabetes mellitus with cutaneous manifestations attending skin outpatient department and other patients admitted in medical wards were included in the study.<strong></strong></p><p class="abstract"><strong>Results:</strong> The common skin disorders were cutaneous manifestations (67%), dermatosis more commonly associated with diabetes (36%), neuropathic and ischemic diabetic skin disease (11%).</p><p class="abstract"><strong>Conclusions:</strong> Most common cutaneous manifestation was cutaneous infections followed by dermatosis more commonly associated with diabetes. Among cutaneous infections fungal infections were more common followed by bacterial infections. Cutaneous infections were more common in patients with poor glycaemic control and the association was found to be statistically significant.</p>

Outcome of Fungal Infection in Patients Undergoing Myelosuppressive Chemotherapy in a Tertiary Care Centre During 12 Years (1995-2006).

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 1384-1384
Author(s):  
Marie von Lilienfeld-Toal ◽  
Axel Glasmacher ◽  
Günter Marklein ◽  
Peter Brossart ◽  
Corinna Hahn-Ast
Keyword(s):  
Research Funding ◽  
Fungal Infections ◽  
Lymphoblastic Leukemia ◽  
Tertiary Care ◽  
Underlying Disease ◽  
Aggressive Lymphoma ◽  
Tertiary Care Centre ◽  
Myelosuppressive Chemotherapy ◽  
Mortality And Morbidity ◽  
Related Mortality

Abstract Abstract 1384 Poster Board I-406 Invasive fungal infections (IFI) contribute significantly to mortality and morbidity in patients receiving myelosuppressive chemotherapy for hematological malignancies. The present study evaluates the incidence of IFI, the overall survival (OS), the infection-related mortality and changes in treatment of IFI in our department from 1995 until 2006. Data of all consecutive chemotherapy courses were retrospectively collected with a standard questionnaire. EORTC/MSG criteria for IFI were applied with a modification: A positive PCR-result for Aspergillus spp. in bronchoalveolar lavage was also defined as probable IFI. In total, 1693 courses of 592 patients were evaluated. Sixty-three percent were given to treat acute myeloid leukemia, the rest for acute lymphoblastic leukemia or aggressive lymphoma. IFI were observed in 139/592 patients (23%, 95% confidence interval (CI) 20-27%), and in 149/1693 (8.8%, 95%CI 8-10%) courses. IFI-related mortality was 57% in 1995-2001 and 29% in 2002-2006, p<0.001. Accordingly, median OS in patients with IFI increased in the later years: 54 days (95%CI 26–82 days) in 1995-2001 versus 229 days (95% CI 35–423 days) in 2002-2006, p=0.001, figure 1. By multivariate analysis, factors predictive for better OS were controlled disease after chemotherapy (hazard ratio (HR) 0.226, p<0.001), possible IFI (in contrast to proven/probable IFI, HR 0.511, p=0.002), age < 60 years (HR 0.611, p=0.015), and use of novel antifungals (HR 0.493, p=0.002). In conclusion, IFI-related mortality decreased and OS in patients with IFI increased significantly in recent years compared to 1995-2001. In our cohort improved OS was associated with controlled underlying disease, certainty of IFI diagnosis (possible), younger age, and the use of novel antifungal agents. Figure 1 p=0.001 Figure 1. p=0.001 Time period ········ 2002-2006 —— 1995-2001 Number at risk 2002-2006 78 28 18 9 6 2 1995-2001 61 8 6 5 5 5 Disclosures: von Lilienfeld-Toal: MSD: Honoraria, Research Funding. Glasmacher: Celgene: Employment, Equity Ownership. Hahn-Ast: MSD: Research Funding.

scholarly journals Study of Dermatophytosis in a Tertiary Care Centre in Central India

2021 ◽  
Vol 10 (8) ◽  
pp. 484-487
Author(s):  
Nirmal Channe ◽  
Supriya S. Tankhiwale
Keyword(s):  
Fungal Infections ◽  
Tertiary Care ◽  
Central India ◽  
Immunosuppressive Drugs ◽  
Conventional Technique ◽  
Tinea Corporis ◽  
Tertiary Care Centre ◽  
Candida Spp ◽  
Superficial Mycoses ◽  
Dermatophytic Fungi

BACKGROUND Mycoses are assuming greater significance both in developed and developing countries particularly due to advent of immunosuppressive drugs and diseases. Dermatophytosis is most common type of cutaneous fungal infections seen in man, though in past few decades non-dermatophytes are also assuming importance. Present study is undertaken to know the pattern of dermatophytosis from our region. METHODS An observational study was conducted on 150 samples of patients with complaints of superficial mycoses. Samples were processed for microscopy on potassium hydroxide (KOH) mount and culture on Sabouraud’s dextrose agar (SDA) with and without cycloheximide and chloramphenicol. Any growth was identified by conventional technique. RESULTS One hundred and fifty samples consisting of 86 skin and 64 nails were studied. Most samples were seen in rainy season and males were predominantly affected. Adults from age of 21 - 50 years were most commonly affected. Most common clinical presentation was tinea corporis (70.93 %). In dermatophytic causes, T. mentagrophytes (36.21 %), T. tonsurans (27.59 %) followed by T. rubrum (15.52 %) were common isolates. In non-dermatophytic causes, candida spp. followed by aspergillus spp. were commonest isolates. CONCLUSIONS Tinea corporis is found to be the commonest presentation. Along with dermatophytes, non-dermatophytic fungi are also emerging as the cause of superficial mycoses. In non-dermatophytic fungi, candida is the commonest species, which is now a days showing drug resistance; hence, identification of causative agent is important for correct and prompt treatment. KEY WORDS Dermatophytosis, Non-Dermatophytic Fungi, Dermatophytic Fungi

scholarly journals Evaluation of paediatric lymphadenopathy at a rural tertiary care centre

2021 ◽  
Vol 8 (3) ◽  
pp. 507
Author(s):  
Mamatha Pakala ◽  
Shreya Tanneru ◽  
Prasada Thanda ◽  
Prabhakar Vuppala
Keyword(s):  
Bacterial Infections ◽  
Viral Infections ◽  
Tertiary Care ◽  
Cervical Lymphadenopathy ◽  
Clinical Findings ◽  
Tuberculous Lymphadenitis ◽  
Paediatric Surgery ◽  
Tertiary Care Centre ◽  
Serological Tests ◽  
Gold Standard Method

Background: The aim and objectives of the present study was to determine the various etiologies of lymphadenopathy in children in our region and its associated clinical findings and prevalence of malignancy in children presented with significant lymphadenopathy.Methods: Sixty-five patients with significant lymphadenopathy charts were reviewed retrospectively from department of Paediatrics and Paediatric Surgery during the period of September 2018-2020. Patient’s records were evaluated in terms of age, gender, complaints, and characteristics of lymph nodes in terms of site, consistency, discharge, sinus and clinical course of a patient. Physical findings of all the cases were noted. Hematological and serological tests were done to know the source of infection. Clinical findings and laboratory results were corroborated with pathological diagnostic tests like FNAC and Excision biopsies in children with significant lymphadenopathyResults: The etiology was confirmed in 94% children and couldn’t be diagnosed in 6% children presented with significant lymphadenopathy. On evaluation commonest etiology was infection with reactive hyperplasia in 58% of children secondary to bacterial or viral infections, Kawasaki disease, suppurative lymphadenitis in 17%, tuberculous lymphadenitis in 14%, and malignancy in 11%. Majority of children presented with cervical lymphadenopathy. An unusual presentation of Non Hodgkin lymphoma as intestinal obstruction with no significant mass per abdomen, a case of nasopharyngeal carcinoma presented as torticollis due to massive unilateral cervical lymphadenopathy were diagnosedConclusions: The most widely encountered cause of lymphadenopathy in children was infection. Most of them are secondary to non specific viral or bacterial infections. The most important concern in children presenting with complaints of lymphadenopathy is the detection of underlying malignant disease. There was significant malignancy rate in our study in children with lymphadenopathy with few atypical presentations. Excisional biopsy is the gold standard method to confirm the diagnosis.

CLINICAL STUDY ON URINARY TRACT INFECTION WITH SPECIAL REFERENCE TO BACTERIOLOGY AND THEIR SENSITIVITY PATTERN IN A TERTIARY CARE CENTRE OF NORTH-BENGAL

2021 ◽  
pp. 44-46
Author(s):  
Achintya Narayan Ray ◽  
Sandip Saha ◽  
Smarajit Banik ◽  
Biplab Mondal ◽  
O P. Pandey
Keyword(s):  
Urinary Tract ◽  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Tertiary Care ◽  
Resistance Pattern ◽  
Tertiary Care Centre ◽  
Study Region ◽  
Sensitivity Pattern ◽  
Tract Infections ◽  
North Bengal

Background: Urinary tract infections (UTIs) are the most common bacterial infection encountered in tertiary care settings UTI is one of the most common bacterial infections in humans and a major cause of morbidity. Its antibiotic sensitivity pattern varies with the widespread availability of antimicrobial agents; UTI has become difcult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents. This prospec Methods: tive and observational Study was conducted on patients attending the outpatient and indoor admitted patients at North Bengal Medical College at Darjeeling district of West Bengal. From 2016 to 2018. A total 100 patients were taken who having clinical features of UTI. The study region covers the various districts of North Bengal. Template was generated in MS excel sheet and analysis was done on SPSS 20.0 software. A Results: mong 100 UTI patients, 34 (34%) were male and 66 (66%) were female. The majority of patients (30%) were 46-60 yrs of age. In the study group symptomatic presentation in order of frequency were, dysuria 85%, urgency74%, fever with chill 60%, hypogastric pain and tenderness 70%, ank pain 30%. E.coli & klebsiella were most common isolates among i.e 66% and11.% respectively. Proteus were sensitive to Netlimycine 90%, Imipenem 87%, Meropenem 79%, Amikacin 75% Gentamycin 68 %, levooxacin 82 % of patients. In the present study, females (66%) Conclusions: were mostly affected and the most common organisms were E.Coli and Klebsiella. These organisms were most sensitive to Amikacin, Nitrofurantoin etc. The sensitivity and resistance pattern of uropathogens to common antimicrobial agents must be taken into account when selecting treatment plans for UTI.

scholarly journals Spectrum of gynecological disorders in geriatric women: a tertiary care centre study

2017 ◽  
Vol 6 (11) ◽  
pp. 4869
Author(s):  
Baseerat Kaur ◽  
Shashi Gupta ◽  
Sudesh Kumar ◽  
Shivali Sharma ◽  
Manvi Verma
Keyword(s):  
Pelvic Organ Prolapse ◽  
Older Women ◽  
Genital Tract ◽  
Primary Care Physicians ◽  
Tertiary Care ◽  
Pelvic Organ ◽  
Carcinoma Cervix ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Urogenital Infections

Background: Older women constitute the fastest growing segment of Indian population. Postmenopausal phase is important and primary care physicians should be aware of common gynaecologic concerns and the potential impact of these on the function and quality of life of older women.Methods: A Prospective cross-sectional study was conducted over a period of one year on 100 postmenopausal women aged 65 years or above, who attended OPD or were hospitalised between November 2015 and October 2016.Results: Literacy rate was 30%. Study population was drawn equally from rural and urban population. Genital tract malignancy was the major gynecological disorder (32%), the commonest being the carcinoma cervix. Next in order was carcinoma ovary and carcinoma endometrium. This was followed by pelvic organ prolapse (26%) and urogenital infections (17%). POP was grade 3 in 85% patients.Conclusions: Pelvic organ prolapse, genital tract malignancies and urogenital infections were the major gynecological problems faced by older women. Moreover, postmenopausal bleeding was a possible underlying cause of malignancy, of which carcinoma cervix tops the list, emphasizing the need for a screening programme in Indian women. There is urgent need to develop dedicated geriatric units and to encourage women to receive routine gynecological check-ups in the early post menopausal period that will enable early diagnosis and treatment.

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